Transmembrane amino acid transporter family protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

amino acid transporter, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X458_LEIDO

TriTrypDb:

LdBPK_310350.1 , LdCL_310008600 , LDHU3_31.0420

Length:

500

Annotations

LeishMANIAdb annotations

An enormously expanded group of various amino acid transporters.. Localization: Cell surface (by feature)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 8
Forrest at al. (procyclic)	no	yes: 8
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 69

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 168
NetGPI	no	yes: 0, no: 169

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	153
GO:0110165	cellular anatomical entity	1	153
GO:0005634	nucleus	5	1
GO:0005737	cytoplasm	2	1
GO:0005886	plasma membrane	3	1
GO:0020016	ciliary pocket	2	1
GO:0020023	kinetoplast	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

Expansion

Sequence features

A0A3S7X458

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X458

Function

Biological processes
Term	Name	Level	Count
GO:0003333	amino acid transmembrane transport	5	16
GO:0006810	transport	3	16
GO:0006811	monoatomic ion transport	4	1
GO:0006812	monoatomic cation transport	5	1
GO:0006820	monoatomic anion transport	5	1
GO:0006865	amino acid transport	5	16
GO:0009987	cellular process	1	16
GO:0015711	organic anion transport	5	1
GO:0015802	basic amino acid transport	6	1
GO:0015819	lysine transport	6	1
GO:0015849	organic acid transport	5	16
GO:0046942	carboxylic acid transport	6	1
GO:0051179	localization	1	16
GO:0051234	establishment of localization	2	16
GO:0055085	transmembrane transport	2	16
GO:0071702	organic substance transport	4	16
GO:0071705	nitrogen compound transport	4	16
GO:1903825	organic acid transmembrane transport	3	16
GO:1905039	carboxylic acid transmembrane transport	4	16

Molecular functions
Term	Name	Level	Count
GO:0005215	transporter activity	1	16
GO:0005342	organic acid transmembrane transporter activity	3	16
GO:0008324	monoatomic cation transmembrane transporter activity	4	1
GO:0008509	monoatomic anion transmembrane transporter activity	4	1
GO:0008514	organic anion transmembrane transporter activity	5	1
GO:0015075	monoatomic ion transmembrane transporter activity	3	1
GO:0015171	amino acid transmembrane transporter activity	5	16
GO:0015174	basic amino acid transmembrane transporter activity	6	1
GO:0015179	L-amino acid transmembrane transporter activity	6	16
GO:0015189	L-lysine transmembrane transporter activity	5	1
GO:0022857	transmembrane transporter activity	2	16
GO:0046943	carboxylic acid transmembrane transporter activity	4	16
GO:0003824	catalytic activity	1	1
GO:0016787	hydrolase activity	2	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	210	214	PF00656	0.434
CLV_NRD_NRD_1	68	70	PF00675	0.508
CLV_NRD_NRD_1	84	86	PF00675	0.502
CLV_PCSK_KEX2_1	68	70	PF00082	0.538
CLV_PCSK_KEX2_1	84	86	PF00082	0.473
CLV_PCSK_PC7_1	64	70	PF00082	0.535
CLV_PCSK_SKI1_1	171	175	PF00082	0.368
CLV_PCSK_SKI1_1	202	206	PF00082	0.574
CLV_PCSK_SKI1_1	226	230	PF00082	0.398
CLV_PCSK_SKI1_1	285	289	PF00082	0.659
DOC_MAPK_FxFP_2	451	454	PF00069	0.438
DOC_MAPK_MEF2A_6	250	259	PF00069	0.557
DOC_MAPK_MEF2A_6	277	286	PF00069	0.451
DOC_PP1_RVXF_1	224	231	PF00149	0.487
DOC_PP2B_LxvP_1	240	243	PF13499	0.372
DOC_PP2B_LxvP_1	429	432	PF13499	0.389
DOC_PP2B_PxIxI_1	431	437	PF00149	0.405
DOC_PP4_FxxP_1	451	454	PF00568	0.402
DOC_USP7_MATH_1	113	117	PF00917	0.428
DOC_USP7_MATH_1	310	314	PF00917	0.495
DOC_USP7_MATH_2	243	249	PF00917	0.550
DOC_WW_Pin1_4	212	217	PF00397	0.381
DOC_WW_Pin1_4	318	323	PF00397	0.556
LIG_14-3-3_CanoR_1	226	231	PF00244	0.383
LIG_14-3-3_CanoR_1	250	259	PF00244	0.545
LIG_14-3-3_CanoR_1	285	294	PF00244	0.402
LIG_14-3-3_CanoR_1	324	328	PF00244	0.562
LIG_BIR_II_1	1	5	PF00653	0.854
LIG_BRCT_BRCA1_1	444	448	PF00533	0.410
LIG_BRCT_BRCA1_1	475	479	PF00533	0.525
LIG_EH1_1	261	269	PF00400	0.356
LIG_eIF4E_1	340	346	PF01652	0.443
LIG_FHA_1	204	210	PF00498	0.416
LIG_FHA_1	227	233	PF00498	0.409
LIG_FHA_1	328	334	PF00498	0.438
LIG_FHA_1	4	10	PF00498	0.756
LIG_FHA_1	475	481	PF00498	0.388
LIG_LIR_Apic_2	97	101	PF02991	0.732
LIG_LIR_Gen_1	179	189	PF02991	0.477
LIG_LIR_Gen_1	299	310	PF02991	0.436
LIG_LIR_Gen_1	312	322	PF02991	0.503
LIG_LIR_Gen_1	395	405	PF02991	0.532
LIG_LIR_Gen_1	455	460	PF02991	0.445
LIG_LIR_Gen_1	476	486	PF02991	0.389
LIG_LIR_Nem_3	147	152	PF02991	0.425
LIG_LIR_Nem_3	179	184	PF02991	0.427
LIG_LIR_Nem_3	299	305	PF02991	0.459
LIG_LIR_Nem_3	395	401	PF02991	0.552
LIG_LIR_Nem_3	445	451	PF02991	0.424
LIG_LIR_Nem_3	468	474	PF02991	0.532
LIG_LIR_Nem_3	476	482	PF02991	0.387
LIG_LIR_Nem_3	494	500	PF02991	0.520
LIG_LIR_Nem_3	61	65	PF02991	0.773
LIG_LYPXL_S_1	452	456	PF13949	0.530
LIG_MLH1_MIPbox_1	475	479	PF16413	0.554
LIG_PALB2_WD40_1	467	475	PF16756	0.641
LIG_PAM2_1	421	433	PF00658	0.271
LIG_PCNA_yPIPBox_3	412	420	PF02747	0.601
LIG_Pex14_1	187	191	PF04695	0.412
LIG_Pex14_2	184	188	PF04695	0.450
LIG_Pex14_2	259	263	PF04695	0.390
LIG_Pex14_2	300	304	PF04695	0.380
LIG_Pex14_2	337	341	PF04695	0.431
LIG_Pex14_2	444	448	PF04695	0.454
LIG_Pex14_2	92	96	PF04695	0.701
LIG_SH2_CRK	102	106	PF00017	0.630
LIG_SH2_CRK	363	367	PF00017	0.350
LIG_SH2_CRK	398	402	PF00017	0.537
LIG_SH2_PTP2	375	378	PF00017	0.413
LIG_SH2_SRC	197	200	PF00017	0.382
LIG_SH2_STAP1	126	130	PF00017	0.263
LIG_SH2_STAP1	149	153	PF00017	0.432
LIG_SH2_STAP1	166	170	PF00017	0.541
LIG_SH2_STAT5	145	148	PF00017	0.400
LIG_SH2_STAT5	152	155	PF00017	0.408
LIG_SH2_STAT5	180	183	PF00017	0.401
LIG_SH2_STAT5	197	200	PF00017	0.381
LIG_SH2_STAT5	251	254	PF00017	0.412
LIG_SH2_STAT5	262	265	PF00017	0.382
LIG_SH2_STAT5	340	343	PF00017	0.403
LIG_SH2_STAT5	348	351	PF00017	0.408
LIG_SH2_STAT5	375	378	PF00017	0.434
LIG_SH2_STAT5	474	477	PF00017	0.537
LIG_SH2_STAT5	478	481	PF00017	0.379
LIG_SH2_STAT5	95	98	PF00017	0.693
LIG_SH3_5	176	180	PF00018	0.592
LIG_SUMO_SIM_anti_2	253	259	PF11976	0.442
LIG_SUMO_SIM_par_1	196	203	PF11976	0.372
LIG_TRAF2_1	313	316	PF00917	0.457
LIG_TYR_ITIM	100	105	PF00017	0.617
LIG_TYR_ITIM	143	148	PF00017	0.450
LIG_TYR_ITIM	260	265	PF00017	0.406
LIG_TYR_ITIM	373	378	PF00017	0.402
LIG_UBA3_1	237	244	PF00899	0.405
LIG_WRC_WIRS_1	188	193	PF05994	0.379
LIG_WRC_WIRS_1	227	232	PF05994	0.467
LIG_WRC_WIRS_1	297	302	PF05994	0.458
LIG_WRC_WIRS_1	405	410	PF05994	0.626
LIG_WRC_WIRS_1	453	458	PF05994	0.454
MOD_CDK_SPxK_1	318	324	PF00069	0.539
MOD_CK1_1	295	301	PF00069	0.450
MOD_CK1_1	3	9	PF00069	0.845
MOD_CK1_1	465	471	PF00069	0.559
MOD_CK2_1	310	316	PF00069	0.428
MOD_CK2_1	49	55	PF00069	0.838
MOD_GlcNHglycan	130	133	PF01048	0.549
MOD_GlcNHglycan	2	5	PF01048	0.641
MOD_GlcNHglycan	270	273	PF01048	0.589
MOD_GlcNHglycan	294	297	PF01048	0.376
MOD_GlcNHglycan	357	360	PF01048	0.601
MOD_GlcNHglycan	444	447	PF01048	0.440
MOD_GlcNHglycan	460	463	PF01048	0.337
MOD_GlcNHglycan	52	55	PF01048	0.621
MOD_GSK3_1	193	200	PF00069	0.433
MOD_GSK3_1	285	292	PF00069	0.421
MOD_GSK3_1	323	330	PF00069	0.571
MOD_GSK3_1	458	465	PF00069	0.549
MOD_N-GLC_1	128	133	PF02516	0.502
MOD_N-GLC_1	462	467	PF02516	0.355
MOD_N-GLC_2	413	415	PF02516	0.536
MOD_NEK2_1	105	110	PF00069	0.551
MOD_NEK2_1	112	117	PF00069	0.409
MOD_NEK2_1	128	133	PF00069	0.337
MOD_NEK2_1	286	291	PF00069	0.345
MOD_NEK2_1	323	328	PF00069	0.572
MOD_NEK2_1	355	360	PF00069	0.435
MOD_NEK2_2	144	149	PF00069	0.409
MOD_NEK2_2	197	202	PF00069	0.494
MOD_PIKK_1	303	309	PF00454	0.444
MOD_PKA_2	323	329	PF00069	0.540
MOD_Plk_1	193	199	PF00069	0.459
MOD_Plk_1	22	28	PF00069	0.695
MOD_Plk_1	462	468	PF00069	0.549
MOD_Plk_1	60	66	PF00069	0.810
MOD_Plk_2-3	27	33	PF00069	0.776
MOD_Plk_4	144	150	PF00069	0.391
MOD_Plk_4	193	199	PF00069	0.436
MOD_Plk_4	226	232	PF00069	0.405
MOD_Plk_4	296	302	PF00069	0.429
MOD_Plk_4	421	427	PF00069	0.389
MOD_Plk_4	452	458	PF00069	0.408
MOD_Plk_4	474	480	PF00069	0.552
MOD_Plk_4	492	498	PF00069	0.386
MOD_ProDKin_1	212	218	PF00069	0.381
MOD_ProDKin_1	318	324	PF00069	0.556
MOD_SUMO_rev_2	35	45	PF00179	0.812
TRG_DiLeu_BaLyEn_6	223	228	PF01217	0.354
TRG_ENDOCYTIC_2	102	105	PF00928	0.626
TRG_ENDOCYTIC_2	13	16	PF00928	0.853
TRG_ENDOCYTIC_2	139	142	PF00928	0.412
TRG_ENDOCYTIC_2	145	148	PF00928	0.427
TRG_ENDOCYTIC_2	151	154	PF00928	0.435
TRG_ENDOCYTIC_2	166	169	PF00928	0.489
TRG_ENDOCYTIC_2	262	265	PF00928	0.407
TRG_ENDOCYTIC_2	314	317	PF00928	0.516
TRG_ENDOCYTIC_2	348	351	PF00928	0.396
TRG_ENDOCYTIC_2	363	366	PF00928	0.354
TRG_ENDOCYTIC_2	375	378	PF00928	0.404
TRG_ENDOCYTIC_2	398	401	PF00928	0.547
TRG_ENDOCYTIC_2	453	456	PF00928	0.509
TRG_ENDOCYTIC_2	478	481	PF00928	0.379
TRG_ENDOCYTIC_2	497	500	PF00928	0.462
TRG_ER_diArg_1	67	69	PF00400	0.766
TRG_ER_diArg_1	84	86	PF00400	0.710

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P285	Leptomonas seymouri	37%	100%
A0A0N0P5D2	Leptomonas seymouri	48%	100%
A0A0N0P613	Leptomonas seymouri	26%	100%
A0A0N0P6F5	Leptomonas seymouri	27%	100%
A0A0N0P6F6	Leptomonas seymouri	42%	100%
A0A0N0P8T9	Leptomonas seymouri	70%	100%
A0A0N0P955	Leptomonas seymouri	44%	100%
A0A0N1I2L5	Leptomonas seymouri	41%	100%
A0A0N1I3F8	Leptomonas seymouri	45%	94%
A0A0N1I3H4	Leptomonas seymouri	49%	91%
A0A0N1I8K7	Leptomonas seymouri	42%	100%
A0A0N1I8W4	Leptomonas seymouri	30%	100%
A0A0N1I9T3	Leptomonas seymouri	44%	100%
A0A0N1IAJ0	Leptomonas seymouri	22%	100%
A0A0N1IMP2	Leptomonas seymouri	66%	99%
A0A0N1PA98	Leptomonas seymouri	36%	81%
A0A0N1PBP2	Leptomonas seymouri	41%	100%
A0A0N1PFD1	Leptomonas seymouri	43%	100%
A0A0S4IV32	Bodo saltans	23%	100%
A0A0S4JAL8	Bodo saltans	22%	90%
A0A0S4JBX6	Bodo saltans	28%	94%
A0A0S4JCF0	Bodo saltans	21%	100%
A0A0S4JHM8	Bodo saltans	27%	100%
A0A0S4JQ87	Bodo saltans	31%	100%
A0A0S4JU02	Bodo saltans	40%	100%
A0A0S4JW15	Bodo saltans	20%	84%
A0A1X0NJR7	Trypanosomatidae	52%	100%
A0A1X0NKS5	Trypanosomatidae	57%	100%
A0A1X0NKV2	Trypanosomatidae	48%	100%
A0A1X0NKW7	Trypanosomatidae	59%	100%
A0A1X0NLA5	Trypanosomatidae	22%	100%
A0A1X0NNX9	Trypanosomatidae	43%	100%
A0A1X0NPV3	Trypanosomatidae	47%	100%
A0A1X0NQH3	Trypanosomatidae	44%	100%
A0A1X0NR26	Trypanosomatidae	45%	100%
A0A1X0NRL3	Trypanosomatidae	49%	100%
A0A1X0NRL7	Trypanosomatidae	44%	100%
A0A1X0NYI3	Trypanosomatidae	46%	100%
A0A1X0P0B5	Trypanosomatidae	22%	91%
A0A1X0P4S1	Trypanosomatidae	24%	100%
A0A1X0P814	Trypanosomatidae	44%	100%
A0A1X0P9N8	Trypanosomatidae	29%	100%
A0A3Q8ID74	Leishmania donovani	47%	100%
A0A3Q8IDG8	Leishmania donovani	47%	100%
A0A3Q8IEP8	Leishmania donovani	48%	100%
A0A3Q8IFZ0	Leishmania donovani	62%	100%
A0A3Q8IG00	Leishmania donovani	44%	100%
A0A3Q8IHG8	Leishmania donovani	94%	100%
A0A3Q8IJH2	Leishmania donovani	48%	100%
A0A3Q8IJX8	Leishmania donovani	44%	100%
A0A3Q8ILE0	Leishmania donovani	45%	100%
A0A3Q8IQG8	Leishmania donovani	29%	100%
A0A3R7JSA0	Trypanosoma rangeli	44%	100%
A0A3R7KDS3	Trypanosoma rangeli	45%	100%
A0A3R7MQD8	Trypanosoma rangeli	22%	100%
A0A3R7N1H9	Trypanosoma rangeli	40%	100%
A0A3R7N2A2	Trypanosoma rangeli	44%	100%
A0A3R7R2W8	Trypanosoma rangeli	44%	100%
A0A3R7RFB5	Trypanosoma rangeli	40%	99%
A0A3R7RQX3	Trypanosoma rangeli	43%	100%
A0A3S5H6T4	Leishmania donovani	80%	100%
A0A3S5H7P4	Leishmania donovani	44%	100%
A0A3S5ISG3	Trypanosoma rangeli	52%	100%
A0A3S7WQ39	Leishmania donovani	44%	100%
A0A3S7X443	Leishmania donovani	100%	100%
A0A3S7X4A1	Leishmania donovani	44%	100%
A0A3S7X4L2	Leishmania donovani	33%	100%
A0A3S7XA86	Leishmania donovani	25%	100%
A0A3S7XCE3	Leishmania donovani	22%	100%
A0A422MW74	Trypanosoma rangeli	41%	97%
A0A422N608	Trypanosoma rangeli	40%	100%
A0A422NBM3	Trypanosoma rangeli	47%	100%
A0A422NBQ2	Trypanosoma rangeli	41%	100%
A0A422NZS1	Trypanosoma rangeli	45%	100%
A1YG32	Pan paniscus	24%	99%
A2VCW5	Rattus norvegicus	24%	100%
A2VE31	Bos taurus	22%	99%
A4H565	Leishmania braziliensis	42%	100%
A4HC75	Leishmania braziliensis	40%	100%
A4HFJ2	Leishmania braziliensis	43%	100%
A4HFT5	Leishmania braziliensis	48%	100%
A4HJ06	Leishmania braziliensis	45%	100%
A4HJ07	Leishmania braziliensis	83%	100%
A4HJ09	Leishmania braziliensis	80%	100%
A4HJ10	Leishmania braziliensis	66%	100%
A4HJ35	Leishmania braziliensis	43%	100%
A4HJ36	Leishmania braziliensis	41%	100%
A4HJ37	Leishmania braziliensis	45%	100%
A4HJ63	Leishmania braziliensis	41%	100%
A4HJF9	Leishmania braziliensis	34%	100%
A4HJG1	Leishmania braziliensis	34%	100%
A4HKQ7	Leishmania braziliensis	43%	100%
A4HNJ6	Leishmania braziliensis	28%	100%
A4HNJ7	Leishmania braziliensis	25%	100%
A4HNQ0	Leishmania braziliensis	29%	100%
A4HTE2	Leishmania infantum	44%	100%
A4HZQ0	Leishmania infantum	45%	100%
A4I2V2	Leishmania infantum	42%	85%
A4I6F1	Leishmania infantum	44%	100%
A4I6F2	Leishmania infantum	48%	100%
A4I6I1	Leishmania infantum	44%	100%
A4I6J8	Leishmania infantum	47%	100%
A4I6J9	Leishmania infantum	99%	100%
A4I6K0	Leishmania infantum	63%	100%
A4I6L3	Leishmania infantum	44%	100%
A4I6L4	Leishmania infantum	44%	100%
A4I6W4	Leishmania infantum	33%	100%
A4I887	Leishmania infantum	48%	100%
A4IC53	Leishmania infantum	26%	100%
A4IC66	Leishmania infantum	25%	100%
A4ICC3	Leishmania infantum	22%	100%
A4ICU5	Leishmania infantum	29%	100%
A6NNN8	Homo sapiens	24%	100%
A7E3U5	Bos taurus	22%	100%
C9ZMB9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
C9ZMD1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
C9ZMD2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZMD3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
C9ZMD4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
C9ZN51	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	51%	100%
C9ZN59	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	100%
C9ZN60	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	100%
C9ZVS1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	95%
C9ZVS2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	93%
C9ZVS3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	94%
C9ZWQ7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZWQ8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZWQ9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZWR0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
C9ZWR1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	92%
C9ZWR7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
C9ZWX2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
C9ZWX3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
C9ZWX4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
C9ZWX5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
C9ZWX6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
C9ZWX7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
C9ZWY0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	100%
C9ZWY1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
D0A362	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
D0AAF6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	50%	100%
D0AAF8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	100%
D0AAG7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
D0AAG8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
E8NHF9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	49%	100%
E8NHS7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	86%
E9AD44	Leishmania major	95%	100%
E9AD45	Leishmania major	48%	100%
E9ADD7	Leishmania major	48%	100%
E9AG08	Leishmania major	27%	100%
E9AG09	Leishmania major	25%	100%
E9AHD7	Leishmania infantum	96%	100%
E9AHD9	Leishmania infantum	47%	100%
E9AHL1	Leishmania infantum	33%	100%
E9AHL2	Leishmania infantum	35%	100%
E9AHL3	Leishmania infantum	33%	100%
E9ALD5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	41%	98%
E9AN82	Leishmania mexicana (strain MHOM/GT/2001/U1103)	21%	100%
E9ASF9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9AUB8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9AVK6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	99%
E9AYW8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	100%
E9AYW9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	44%	100%
E9AZ62	Leishmania mexicana (strain MHOM/GT/2001/U1103)	48%	100%
E9B1I4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
E9B1I6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	61%	100%
E9B1K7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	44%	100%
E9B1K8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	43%	100%
E9B1K9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	47%	100%
E9B1N8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9B1N9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9B1Y0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	100%
E9B345	Leishmania mexicana (strain MHOM/GT/2001/U1103)	43%	100%
E9B761	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9B762	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
F4KBM7	Arabidopsis thaliana	23%	100%
G3UVW3	Mus musculus	24%	100%
O74327	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	100%
P34479	Caenorhabditis elegans	23%	100%
P36062	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	23%	72%
P39981	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	21%	100%
Q28HE5	Xenopus tropicalis	24%	100%
Q28I47	Xenopus tropicalis	23%	100%
Q3U1J0	Mus musculus	24%	100%
Q495N2	Homo sapiens	22%	100%
Q4Q072	Leishmania major	22%	100%
Q4Q236	Leishmania major	30%	100%
Q4Q509	Leishmania major	48%	100%
Q4Q680	Leishmania major	33%	100%
Q4Q683	Leishmania major	33%	100%
Q4Q6H5	Leishmania major	44%	100%
Q4Q6K5	Leishmania major	45%	100%
Q4Q6K6	Leishmania major	46%	100%
Q4Q6M8	Leishmania major	61%	100%
Q4Q6M9	Leishmania major	97%	100%
Q4Q6N0	Leishmania major	96%	100%
Q4Q6N1	Leishmania major	48%	100%
Q4QBX3	Leishmania major	44%	100%
Q4QIH0	Leishmania major	43%	100%
Q4V8B1	Rattus norvegicus	22%	100%
Q503G8	Danio rerio	27%	100%
Q5E9S9	Bos taurus	25%	100%
Q5F468	Gallus gallus	23%	100%
Q5HZH7	Mus musculus	24%	100%
Q5R443	Pongo abelii	25%	100%
Q5R9F5	Pongo abelii	22%	100%
Q5SPB1	Danio rerio	24%	99%
Q5XH90	Xenopus tropicalis	23%	100%
Q6DEL1	Danio rerio	22%	100%
Q6DFE7	Xenopus laevis	26%	100%
Q6JWR2	Rattus norvegicus	23%	100%
Q6WWW3	Rattus norvegicus	24%	100%
Q811P0	Mus musculus	21%	100%
Q8BWH0	Mus musculus	23%	100%
Q8CFE6	Mus musculus	23%	99%
Q8GYS4	Arabidopsis thaliana	22%	91%
Q8IZM9	Homo sapiens	24%	100%
Q8K2P7	Mus musculus	24%	100%
Q8WUX1	Homo sapiens	25%	100%
Q96QD8	Homo sapiens	24%	99%
Q99624	Homo sapiens	24%	99%
Q9DCP2	Mus musculus	25%	99%
Q9H2H9	Homo sapiens	25%	100%
Q9JHE5	Rattus norvegicus	23%	99%
Q9JHZ9	Rattus norvegicus	25%	99%
Q9JM15	Rattus norvegicus	24%	100%
Q9LI61	Arabidopsis thaliana	23%	100%
Q9LYM2	Arabidopsis thaliana	23%	100%
Q9M8L9	Arabidopsis thaliana	25%	100%
Q9NVC3	Homo sapiens	22%	100%
Q9VT04	Drosophila melanogaster	22%	100%
V5AXD0	Trypanosoma cruzi	25%	100%
V5AZP2	Trypanosoma cruzi	45%	83%
V5B9A6	Trypanosoma cruzi	50%	100%
V5BA72	Trypanosoma cruzi	47%	100%
V5BH70	Trypanosoma cruzi	42%	100%
V5BIJ1	Trypanosoma cruzi	50%	89%
V5BMG4	Trypanosoma cruzi	46%	100%
V5BQ72	Trypanosoma cruzi	22%	89%
V5BTX5	Trypanosoma cruzi	25%	99%
V5D7K9	Trypanosoma cruzi	41%	100%
V5DCG4	Trypanosoma cruzi	41%	100%
V5DKR4	Trypanosoma cruzi	42%	100%