Transmembrane amino acid transporter family protein

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

amino acid transporter, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X443_LEIDO

TriTrypDb:

LdBPK_310350.1 , LdCL_310008700 , LDHU3_31.0420

Length:

467

Annotations

LeishMANIAdb annotations

An enormously expanded group of various amino acid transporters.. Localization: Cell surface (by feature)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 8
Forrest at al. (procyclic)	no	yes: 10
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 72

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 182
NetGPI	no	yes: 0, no: 183

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	166
GO:0110165	cellular anatomical entity	1	166
GO:0005634	nucleus	5	1
GO:0005737	cytoplasm	2	1
GO:0005886	plasma membrane	3	1
GO:0020016	ciliary pocket	2	1
GO:0020023	kinetoplast	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1

Expansion

Sequence features

A0A3S7X443

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X443

Function

Biological processes
Term	Name	Level	Count
GO:0003333	amino acid transmembrane transport	5	18
GO:0006810	transport	3	18
GO:0006811	monoatomic ion transport	4	1
GO:0006812	monoatomic cation transport	5	1
GO:0006820	monoatomic anion transport	5	1
GO:0006865	amino acid transport	5	18
GO:0009987	cellular process	1	18
GO:0015711	organic anion transport	5	1
GO:0015802	basic amino acid transport	6	1
GO:0015819	lysine transport	6	1
GO:0015849	organic acid transport	5	18
GO:0046942	carboxylic acid transport	6	1
GO:0051179	localization	1	18
GO:0051234	establishment of localization	2	18
GO:0055085	transmembrane transport	2	18
GO:0071702	organic substance transport	4	18
GO:0071705	nitrogen compound transport	4	18
GO:1903825	organic acid transmembrane transport	3	18
GO:1905039	carboxylic acid transmembrane transport	4	18

Molecular functions
Term	Name	Level	Count
GO:0005215	transporter activity	1	18
GO:0005342	organic acid transmembrane transporter activity	3	18
GO:0008324	monoatomic cation transmembrane transporter activity	4	1
GO:0008509	monoatomic anion transmembrane transporter activity	4	1
GO:0008514	organic anion transmembrane transporter activity	5	1
GO:0015075	monoatomic ion transmembrane transporter activity	3	1
GO:0015171	amino acid transmembrane transporter activity	5	18
GO:0015174	basic amino acid transmembrane transporter activity	6	1
GO:0015179	L-amino acid transmembrane transporter activity	6	18
GO:0015189	L-lysine transmembrane transporter activity	5	1
GO:0022857	transmembrane transporter activity	2	18
GO:0046943	carboxylic acid transmembrane transporter activity	4	18
GO:0003824	catalytic activity	1	2
GO:0016787	hydrolase activity	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	177	181	PF00656	0.337
CLV_NRD_NRD_1	35	37	PF00675	0.420
CLV_NRD_NRD_1	51	53	PF00675	0.384
CLV_PCSK_KEX2_1	35	37	PF00082	0.444
CLV_PCSK_KEX2_1	51	53	PF00082	0.378
CLV_PCSK_PC7_1	31	37	PF00082	0.484
CLV_PCSK_SKI1_1	138	142	PF00082	0.274
CLV_PCSK_SKI1_1	169	173	PF00082	0.476
CLV_PCSK_SKI1_1	193	197	PF00082	0.302
CLV_PCSK_SKI1_1	252	256	PF00082	0.562
DEG_Nend_UBRbox_2	1	3	PF02207	0.523
DOC_MAPK_FxFP_2	418	421	PF00069	0.342
DOC_MAPK_MEF2A_6	217	226	PF00069	0.461
DOC_MAPK_MEF2A_6	244	253	PF00069	0.359
DOC_PP1_RVXF_1	191	198	PF00149	0.391
DOC_PP2B_LxvP_1	207	210	PF13499	0.277
DOC_PP2B_LxvP_1	396	399	PF13499	0.297
DOC_PP2B_PxIxI_1	398	404	PF00149	0.306
DOC_PP4_FxxP_1	418	421	PF00568	0.310
DOC_USP7_MATH_1	277	281	PF00917	0.392
DOC_USP7_MATH_1	80	84	PF00917	0.332
DOC_USP7_MATH_2	210	216	PF00917	0.451
DOC_WW_Pin1_4	179	184	PF00397	0.287
DOC_WW_Pin1_4	285	290	PF00397	0.452
LIG_14-3-3_CanoR_1	193	198	PF00244	0.288
LIG_14-3-3_CanoR_1	217	226	PF00244	0.449
LIG_14-3-3_CanoR_1	252	261	PF00244	0.311
LIG_14-3-3_CanoR_1	291	295	PF00244	0.471
LIG_BRCT_BRCA1_1	411	415	PF00533	0.314
LIG_BRCT_BRCA1_1	442	446	PF00533	0.408
LIG_EH1_1	228	236	PF00400	0.259
LIG_eIF4E_1	307	313	PF01652	0.344
LIG_FHA_1	171	177	PF00498	0.323
LIG_FHA_1	194	200	PF00498	0.315
LIG_FHA_1	295	301	PF00498	0.348
LIG_FHA_1	442	448	PF00498	0.293
LIG_LIR_Apic_2	64	68	PF02991	0.636
LIG_LIR_Gen_1	146	156	PF02991	0.379
LIG_LIR_Gen_1	266	277	PF02991	0.336
LIG_LIR_Gen_1	279	289	PF02991	0.404
LIG_LIR_Gen_1	362	372	PF02991	0.437
LIG_LIR_Gen_1	422	427	PF02991	0.420
LIG_LIR_Gen_1	443	453	PF02991	0.293
LIG_LIR_Nem_3	114	119	PF02991	0.329
LIG_LIR_Nem_3	146	151	PF02991	0.327
LIG_LIR_Nem_3	266	272	PF02991	0.351
LIG_LIR_Nem_3	28	32	PF02991	0.669
LIG_LIR_Nem_3	362	368	PF02991	0.457
LIG_LIR_Nem_3	412	418	PF02991	0.329
LIG_LIR_Nem_3	435	441	PF02991	0.437
LIG_LIR_Nem_3	443	449	PF02991	0.294
LIG_LIR_Nem_3	461	467	PF02991	0.384
LIG_LYPXL_S_1	419	423	PF13949	0.432
LIG_MLH1_MIPbox_1	442	446	PF16413	0.456
LIG_PALB2_WD40_1	434	442	PF16756	0.547
LIG_PAM2_1	388	400	PF00658	0.171
LIG_PCNA_yPIPBox_3	379	387	PF02747	0.500
LIG_Pex14_1	154	158	PF04695	0.318
LIG_Pex14_2	151	155	PF04695	0.355
LIG_Pex14_2	226	230	PF04695	0.295
LIG_Pex14_2	267	271	PF04695	0.282
LIG_Pex14_2	304	308	PF04695	0.325
LIG_Pex14_2	411	415	PF04695	0.357
LIG_Pex14_2	59	63	PF04695	0.598
LIG_SH2_CRK	330	334	PF00017	0.253
LIG_SH2_CRK	365	369	PF00017	0.444
LIG_SH2_CRK	69	73	PF00017	0.532
LIG_SH2_PTP2	342	345	PF00017	0.322
LIG_SH2_SRC	164	167	PF00017	0.286
LIG_SH2_STAP1	116	120	PF00017	0.330
LIG_SH2_STAP1	133	137	PF00017	0.455
LIG_SH2_STAP1	93	97	PF00017	0.164
LIG_SH2_STAT5	112	115	PF00017	0.308
LIG_SH2_STAT5	119	122	PF00017	0.319
LIG_SH2_STAT5	147	150	PF00017	0.303
LIG_SH2_STAT5	164	167	PF00017	0.299
LIG_SH2_STAT5	218	221	PF00017	0.315
LIG_SH2_STAT5	229	232	PF00017	0.294
LIG_SH2_STAT5	307	310	PF00017	0.309
LIG_SH2_STAT5	315	318	PF00017	0.317
LIG_SH2_STAT5	342	345	PF00017	0.350
LIG_SH2_STAT5	441	444	PF00017	0.441
LIG_SH2_STAT5	445	448	PF00017	0.282
LIG_SH2_STAT5	62	65	PF00017	0.589
LIG_SH3_5	143	147	PF00018	0.495
LIG_SUMO_SIM_anti_2	220	226	PF11976	0.347
LIG_SUMO_SIM_par_1	163	170	PF11976	0.278
LIG_TRAF2_1	280	283	PF00917	0.358
LIG_TYR_ITIM	110	115	PF00017	0.359
LIG_TYR_ITIM	227	232	PF00017	0.312
LIG_TYR_ITIM	340	345	PF00017	0.306
LIG_TYR_ITIM	67	72	PF00017	0.520
LIG_UBA3_1	204	211	PF00899	0.311
LIG_WRC_WIRS_1	155	160	PF05994	0.281
LIG_WRC_WIRS_1	194	199	PF05994	0.383
LIG_WRC_WIRS_1	264	269	PF05994	0.344
LIG_WRC_WIRS_1	372	377	PF05994	0.474
LIG_WRC_WIRS_1	420	425	PF05994	0.339
MOD_CDK_SPxK_1	285	291	PF00069	0.437
MOD_CK1_1	262	268	PF00069	0.327
MOD_CK1_1	432	438	PF00069	0.458
MOD_CK2_1	16	22	PF00069	0.703
MOD_CK2_1	277	283	PF00069	0.330
MOD_GlcNHglycan	19	22	PF01048	0.486
MOD_GlcNHglycan	237	240	PF01048	0.494
MOD_GlcNHglycan	261	264	PF01048	0.277
MOD_GlcNHglycan	324	327	PF01048	0.481
MOD_GlcNHglycan	411	414	PF01048	0.352
MOD_GlcNHglycan	427	430	PF01048	0.259
MOD_GlcNHglycan	97	100	PF01048	0.455
MOD_GSK3_1	160	167	PF00069	0.333
MOD_GSK3_1	252	259	PF00069	0.313
MOD_GSK3_1	290	297	PF00069	0.479
MOD_GSK3_1	425	432	PF00069	0.453
MOD_N-GLC_1	429	434	PF02516	0.259
MOD_N-GLC_1	95	100	PF02516	0.404
MOD_N-GLC_2	380	382	PF02516	0.438
MOD_NEK2_1	253	258	PF00069	0.251
MOD_NEK2_1	290	295	PF00069	0.477
MOD_NEK2_1	322	327	PF00069	0.327
MOD_NEK2_1	72	77	PF00069	0.458
MOD_NEK2_1	79	84	PF00069	0.315
MOD_NEK2_1	95	100	PF00069	0.239
MOD_NEK2_2	111	116	PF00069	0.320
MOD_NEK2_2	164	169	PF00069	0.396
MOD_PIKK_1	270	276	PF00454	0.346
MOD_PKA_2	290	296	PF00069	0.446
MOD_Plk_1	160	166	PF00069	0.363
MOD_Plk_1	27	33	PF00069	0.693
MOD_Plk_1	429	435	PF00069	0.452
MOD_Plk_4	111	117	PF00069	0.296
MOD_Plk_4	160	166	PF00069	0.335
MOD_Plk_4	193	199	PF00069	0.316
MOD_Plk_4	263	269	PF00069	0.334
MOD_Plk_4	388	394	PF00069	0.294
MOD_Plk_4	419	425	PF00069	0.369
MOD_Plk_4	441	447	PF00069	0.457
MOD_Plk_4	459	465	PF00069	0.254
MOD_ProDKin_1	179	185	PF00069	0.287
MOD_ProDKin_1	285	291	PF00069	0.452
MOD_SUMO_rev_2	2	12	PF00179	0.708
TRG_DiLeu_BaLyEn_6	190	195	PF01217	0.259
TRG_ENDOCYTIC_2	106	109	PF00928	0.314
TRG_ENDOCYTIC_2	112	115	PF00928	0.330
TRG_ENDOCYTIC_2	118	121	PF00928	0.339
TRG_ENDOCYTIC_2	133	136	PF00928	0.398
TRG_ENDOCYTIC_2	229	232	PF00928	0.311
TRG_ENDOCYTIC_2	281	284	PF00928	0.423
TRG_ENDOCYTIC_2	315	318	PF00928	0.298
TRG_ENDOCYTIC_2	330	333	PF00928	0.249
TRG_ENDOCYTIC_2	342	345	PF00928	0.321
TRG_ENDOCYTIC_2	365	368	PF00928	0.451
TRG_ENDOCYTIC_2	420	423	PF00928	0.421
TRG_ENDOCYTIC_2	445	448	PF00928	0.284
TRG_ENDOCYTIC_2	464	467	PF00928	0.362
TRG_ENDOCYTIC_2	69	72	PF00928	0.528
TRG_ER_diArg_1	34	36	PF00400	0.651
TRG_ER_diArg_1	51	53	PF00400	0.607

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P285	Leptomonas seymouri	38%	95%
A0A0N0P5D2	Leptomonas seymouri	48%	97%
A0A0N0P613	Leptomonas seymouri	26%	100%
A0A0N0P6F5	Leptomonas seymouri	27%	100%
A0A0N0P6F6	Leptomonas seymouri	42%	96%
A0A0N0P8T9	Leptomonas seymouri	76%	94%
A0A0N0P955	Leptomonas seymouri	44%	98%
A0A0N1I2L5	Leptomonas seymouri	41%	97%
A0A0N1I3F8	Leptomonas seymouri	45%	88%
A0A0N1I3H4	Leptomonas seymouri	49%	85%
A0A0N1I8K7	Leptomonas seymouri	42%	95%
A0A0N1I8W4	Leptomonas seymouri	30%	96%
A0A0N1I9T3	Leptomonas seymouri	45%	97%
A0A0N1IAJ0	Leptomonas seymouri	23%	97%
A0A0N1IMP2	Leptomonas seymouri	66%	92%
A0A0N1PA98	Leptomonas seymouri	36%	76%
A0A0N1PBP2	Leptomonas seymouri	44%	94%
A0A0N1PFD1	Leptomonas seymouri	43%	93%
A0A0S4IV32	Bodo saltans	23%	95%
A0A0S4JAL8	Bodo saltans	22%	84%
A0A0S4JBX6	Bodo saltans	28%	88%
A0A0S4JCF0	Bodo saltans	21%	100%
A0A0S4JHM8	Bodo saltans	27%	99%
A0A0S4JQ87	Bodo saltans	31%	100%
A0A0S4JU02	Bodo saltans	40%	96%
A0A0S4JW15	Bodo saltans	20%	78%
A0A1X0NJR7	Trypanosomatidae	52%	95%
A0A1X0NKS5	Trypanosomatidae	57%	98%
A0A1X0NKV2	Trypanosomatidae	48%	93%
A0A1X0NKW7	Trypanosomatidae	59%	99%
A0A1X0NLA5	Trypanosomatidae	22%	100%
A0A1X0NNX9	Trypanosomatidae	43%	100%
A0A1X0NPV3	Trypanosomatidae	47%	100%
A0A1X0NQH3	Trypanosomatidae	44%	100%
A0A1X0NR26	Trypanosomatidae	45%	100%
A0A1X0NRL3	Trypanosomatidae	49%	100%
A0A1X0NRL7	Trypanosomatidae	44%	98%
A0A1X0NYI3	Trypanosomatidae	46%	94%
A0A1X0P0B5	Trypanosomatidae	22%	85%
A0A1X0P1N2	Trypanosomatidae	26%	100%
A0A1X0P4S1	Trypanosomatidae	24%	100%
A0A1X0P814	Trypanosomatidae	44%	96%
A0A1X0P9N8	Trypanosomatidae	29%	100%
A0A3Q8ICL1	Leishmania donovani	37%	77%
A0A3Q8ID74	Leishmania donovani	47%	100%
A0A3Q8IDG8	Leishmania donovani	47%	100%
A0A3Q8IEP8	Leishmania donovani	48%	100%
A0A3Q8IFZ0	Leishmania donovani	64%	100%
A0A3Q8IG00	Leishmania donovani	44%	100%
A0A3Q8IGE6	Leishmania donovani	35%	80%
A0A3Q8IHG8	Leishmania donovani	97%	100%
A0A3Q8IHH7	Leishmania donovani	27%	96%
A0A3Q8IJH2	Leishmania donovani	48%	100%
A0A3Q8IJX8	Leishmania donovani	44%	100%
A0A3Q8ILE0	Leishmania donovani	45%	100%
A0A3Q8IQG8	Leishmania donovani	29%	100%
A0A3R7JSA0	Trypanosoma rangeli	45%	98%
A0A3R7KDS3	Trypanosoma rangeli	45%	100%
A0A3R7MQD8	Trypanosoma rangeli	22%	100%
A0A3R7N1H9	Trypanosoma rangeli	40%	96%
A0A3R7N2A2	Trypanosoma rangeli	44%	100%
A0A3R7R2W8	Trypanosoma rangeli	44%	100%
A0A3R7RFB5	Trypanosoma rangeli	40%	92%
A0A3R7RQX3	Trypanosoma rangeli	45%	98%
A0A3S5H6T4	Leishmania donovani	83%	100%
A0A3S5H7P4	Leishmania donovani	44%	100%
A0A3S5ISG3	Trypanosoma rangeli	52%	95%
A0A3S7WQ39	Leishmania donovani	44%	100%
A0A3S7X458	Leishmania donovani	100%	93%
A0A3S7X4A1	Leishmania donovani	44%	97%
A0A3S7X4L2	Leishmania donovani	36%	77%
A0A3S7X4N4	Leishmania donovani	36%	77%
A0A3S7X4P0	Leishmania donovani	36%	77%
A0A3S7XA86	Leishmania donovani	25%	100%
A0A3S7XCE3	Leishmania donovani	22%	98%
A0A422MW74	Trypanosoma rangeli	41%	91%
A0A422N608	Trypanosoma rangeli	40%	96%
A0A422NBM3	Trypanosoma rangeli	47%	99%
A0A422NBQ2	Trypanosoma rangeli	41%	100%
A0A422NZS1	Trypanosoma rangeli	45%	99%
A1YG32	Pan paniscus	24%	92%
A2VCW5	Rattus norvegicus	24%	97%
A2VE31	Bos taurus	22%	92%
A4H565	Leishmania braziliensis	46%	100%
A4HC75	Leishmania braziliensis	40%	100%
A4HFJ2	Leishmania braziliensis	45%	100%
A4HFT5	Leishmania braziliensis	48%	100%
A4HJ06	Leishmania braziliensis	46%	100%
A4HJ07	Leishmania braziliensis	87%	100%
A4HJ09	Leishmania braziliensis	83%	100%
A4HJ10	Leishmania braziliensis	66%	100%
A4HJ35	Leishmania braziliensis	43%	100%
A4HJ36	Leishmania braziliensis	41%	100%
A4HJ37	Leishmania braziliensis	45%	100%
A4HJ63	Leishmania braziliensis	41%	100%
A4HJF8	Leishmania braziliensis	37%	76%
A4HJF9	Leishmania braziliensis	34%	100%
A4HJG1	Leishmania braziliensis	34%	100%
A4HJG3	Leishmania braziliensis	37%	76%
A4HJG5	Leishmania braziliensis	38%	76%
A4HKQ7	Leishmania braziliensis	43%	100%
A4HNJ6	Leishmania braziliensis	28%	100%
A4HNJ7	Leishmania braziliensis	25%	100%
A4HNQ0	Leishmania braziliensis	29%	100%
A4HTE2	Leishmania infantum	44%	100%
A4HZQ0	Leishmania infantum	45%	100%
A4I2V2	Leishmania infantum	42%	79%
A4I6F1	Leishmania infantum	44%	100%
A4I6F2	Leishmania infantum	48%	100%
A4I6I1	Leishmania infantum	44%	100%
A4I6J8	Leishmania infantum	47%	100%
A4I6J9	Leishmania infantum	99%	100%
A4I6K0	Leishmania infantum	65%	100%
A4I6L3	Leishmania infantum	44%	100%
A4I6L4	Leishmania infantum	44%	100%
A4I6W4	Leishmania infantum	36%	77%
A4I887	Leishmania infantum	48%	100%
A4I914	Leishmania infantum	27%	96%
A4IC53	Leishmania infantum	26%	100%
A4IC66	Leishmania infantum	25%	100%
A4ICC3	Leishmania infantum	22%	98%
A4ICU5	Leishmania infantum	29%	100%
A6NNN8	Homo sapiens	24%	100%
A7E3U5	Bos taurus	22%	100%
C9ZMB9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	99%
C9ZMD1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	95%
C9ZMD2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	99%
C9ZMD3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	95%
C9ZMD4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	99%
C9ZN51	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	51%	100%
C9ZN59	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	96%
C9ZN60	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	99%
C9ZVS1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	89%
C9ZVS2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	87%
C9ZVS3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	88%
C9ZWQ7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZWQ8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZWQ9	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	40%	100%
C9ZWR0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
C9ZWR1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	44%	86%
C9ZWR7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
C9ZWX2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
C9ZWX3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
C9ZWX4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
C9ZWX5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
C9ZWX6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
C9ZWX7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	100%
C9ZWY0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	99%
C9ZWY1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	99%
D0A362	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
D0AAF6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	50%	100%
D0AAF8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	100%
D0AAG7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	94%
D0AAG8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	95%
E8NHF9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	49%	100%
E8NHS7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	34%	81%
E9AD44	Leishmania major	96%	100%
E9AD45	Leishmania major	48%	100%
E9ADD7	Leishmania major	48%	100%
E9AG08	Leishmania major	27%	100%
E9AG09	Leishmania major	25%	100%
E9AHD7	Leishmania infantum	99%	100%
E9AHD9	Leishmania infantum	47%	100%
E9AHK8	Leishmania infantum	98%	100%
E9AHL1	Leishmania infantum	36%	77%
E9AHL2	Leishmania infantum	35%	100%
E9AHL3	Leishmania infantum	37%	77%
E9ALD5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	43%	100%
E9AN82	Leishmania mexicana (strain MHOM/GT/2001/U1103)	21%	96%
E9ASF9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9AUB8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	23%	100%
E9AVK6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	45%	100%
E9AYW8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
E9AYW9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	47%	100%
E9AZ62	Leishmania mexicana (strain MHOM/GT/2001/U1103)	48%	100%
E9B1I4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
E9B1I6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	63%	100%
E9B1K7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	44%	100%
E9B1K8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	43%	100%
E9B1K9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	47%	100%
E9B1N8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9B1N9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	42%	100%
E9B1Y0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	32%	77%
E9B345	Leishmania mexicana (strain MHOM/GT/2001/U1103)	47%	100%
E9B3X9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	96%
E9B761	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
E9B762	Leishmania mexicana (strain MHOM/GT/2001/U1103)	26%	100%
F4KBM7	Arabidopsis thaliana	23%	100%
G3UVW3	Mus musculus	24%	100%
O74327	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	25%	100%
P34479	Caenorhabditis elegans	23%	100%
P39981	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	21%	97%
P40501	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	24%	95%
Q28HE5	Xenopus tropicalis	24%	100%
Q28I47	Xenopus tropicalis	23%	100%
Q3U1J0	Mus musculus	24%	97%
Q495N2	Homo sapiens	22%	99%
Q4Q072	Leishmania major	22%	98%
Q4Q236	Leishmania major	30%	100%
Q4Q445	Leishmania major	26%	96%
Q4Q509	Leishmania major	48%	100%
Q4Q680	Leishmania major	34%	77%
Q4Q682	Leishmania major	35%	80%
Q4Q683	Leishmania major	34%	77%
Q4Q6H5	Leishmania major	44%	100%
Q4Q6K5	Leishmania major	45%	100%
Q4Q6K6	Leishmania major	46%	100%
Q4Q6M8	Leishmania major	66%	100%
Q4Q6M9	Leishmania major	97%	100%
Q4Q6N0	Leishmania major	97%	100%
Q4Q6N1	Leishmania major	48%	100%
Q4QBX3	Leishmania major	44%	100%
Q4QIH0	Leishmania major	43%	100%
Q4V8B1	Rattus norvegicus	22%	98%
Q503G8	Danio rerio	26%	100%
Q5E9S9	Bos taurus	25%	98%
Q5F468	Gallus gallus	23%	93%
Q5HZH7	Mus musculus	25%	100%
Q5R443	Pongo abelii	25%	96%
Q5R9F5	Pongo abelii	22%	100%
Q5SPB1	Danio rerio	24%	93%
Q5XH90	Xenopus tropicalis	23%	95%
Q6DEL1	Danio rerio	22%	100%
Q6DFE7	Xenopus laevis	26%	100%
Q6JWR2	Rattus norvegicus	23%	100%
Q6WWW3	Rattus norvegicus	24%	100%
Q811P0	Mus musculus	21%	98%
Q8BWH0	Mus musculus	23%	100%
Q8CFE6	Mus musculus	23%	93%
Q8GYS4	Arabidopsis thaliana	22%	85%
Q8IZM9	Homo sapiens	24%	100%
Q8K2P7	Mus musculus	24%	96%
Q8WUX1	Homo sapiens	25%	99%
Q96QD8	Homo sapiens	24%	92%
Q99624	Homo sapiens	24%	93%
Q9DCP2	Mus musculus	25%	92%
Q9H2H9	Homo sapiens	25%	96%
Q9JHE5	Rattus norvegicus	23%	93%
Q9JHZ9	Rattus norvegicus	25%	93%
Q9JM15	Rattus norvegicus	24%	96%
Q9LI61	Arabidopsis thaliana	23%	100%
Q9LYM2	Arabidopsis thaliana	23%	100%
Q9M8L9	Arabidopsis thaliana	25%	96%
Q9NVC3	Homo sapiens	22%	100%
Q9VT04	Drosophila melanogaster	22%	99%
V5AXD0	Trypanosoma cruzi	25%	100%
V5AZP2	Trypanosoma cruzi	45%	77%
V5B9A6	Trypanosoma cruzi	50%	100%
V5BA72	Trypanosoma cruzi	47%	100%
V5BH70	Trypanosoma cruzi	42%	100%
V5BIJ1	Trypanosoma cruzi	53%	83%
V5BMG4	Trypanosoma cruzi	46%	99%
V5BQ72	Trypanosoma cruzi	22%	83%
V5BTX5	Trypanosoma cruzi	25%	92%
V5D7K9	Trypanosoma cruzi	41%	100%
V5DCG4	Trypanosoma cruzi	44%	100%
V5DKR4	Trypanosoma cruzi	42%	100%