Peptidyl-prolyl cis-trans isomerase

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

cyclophilin, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X410_LEIDO

TriTrypDb:

LdBPK_310060.1 , LdCL_310005400 , LDHU3_31.0080

Length:

229

Annotations

LeishMANIAdb annotations

A large collection of conserved eukaryotic peptidyl-prolyl cis-trans isomerases. Some members of this group are secreted (into the ER).. Localization: Cytoplasmic (by homology) / ER (by homology)

Annotations by Jardim et al.

Chaperone/Protein Folding, Peptidyl-prolyl cis-trans isomerase CYP5

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 3, no: 11
NetGPI	no	yes: 0, no: 14

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3S7X410

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X410

PDB structure(s): 2hqj_A

Function

Biological processes
Term	Name	Level	Count
GO:0000413	protein peptidyl-prolyl isomerization	7	15
GO:0006457	protein folding	2	15
GO:0006807	nitrogen compound metabolic process	2	15
GO:0008152	metabolic process	1	15
GO:0009987	cellular process	1	15
GO:0018193	peptidyl-amino acid modification	5	15
GO:0018208	peptidyl-proline modification	6	15
GO:0019538	protein metabolic process	3	15
GO:0036211	protein modification process	4	15
GO:0043170	macromolecule metabolic process	3	15
GO:0043412	macromolecule modification	4	15
GO:0044238	primary metabolic process	2	15
GO:0071704	organic substance metabolic process	2	15
GO:1901564	organonitrogen compound metabolic process	3	15

Molecular functions
Term	Name	Level	Count
GO:0003755	peptidyl-prolyl cis-trans isomerase activity	3	15
GO:0003824	catalytic activity	1	15
GO:0016853	isomerase activity	2	15
GO:0016859	cis-trans isomerase activity	3	15
GO:0140096	catalytic activity, acting on a protein	2	15
GO:0005488	binding	1	1
GO:0016018	cyclosporin A binding	4	1
GO:0033218	amide binding	2	1
GO:0042277	peptide binding	3	1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	96	100	PF00656	0.221
CLV_PCSK_SKI1_1	101	105	PF00082	0.389
CLV_PCSK_SKI1_1	214	218	PF00082	0.461
CLV_PCSK_SKI1_1	45	49	PF00082	0.371
DEG_SCF_FBW7_1	32	39	PF00400	0.370
DOC_CKS1_1	205	210	PF01111	0.283
DOC_CKS1_1	33	38	PF01111	0.363
DOC_PP1_RVXF_1	183	190	PF00149	0.253
DOC_PP1_RVXF_1	43	49	PF00149	0.355
DOC_PP1_RVXF_1	67	73	PF00149	0.363
DOC_USP7_MATH_1	14	18	PF00917	0.569
DOC_USP7_MATH_1	20	24	PF00917	0.543
DOC_WW_Pin1_4	204	209	PF00397	0.259
DOC_WW_Pin1_4	32	37	PF00397	0.444
DOC_WW_Pin1_4	94	99	PF00397	0.301
LIG_14-3-3_CanoR_1	4	10	PF00244	0.487
LIG_14-3-3_CanoR_1	91	98	PF00244	0.221
LIG_APCC_ABBA_1	72	77	PF00400	0.253
LIG_BIR_II_1	1	5	PF00653	0.475
LIG_BRCT_BRCA1_1	169	173	PF00533	0.253
LIG_BRCT_BRCA1_1	43	47	PF00533	0.393
LIG_BRCT_BRCA1_1	55	59	PF00533	0.491
LIG_FHA_1	213	219	PF00498	0.311
LIG_FHA_1	76	82	PF00498	0.323
LIG_FHA_2	94	100	PF00498	0.236
LIG_LIR_Apic_2	203	208	PF02991	0.329
LIG_LIR_Apic_2	30	36	PF02991	0.525
LIG_LIR_Gen_1	71	80	PF02991	0.370
LIG_LIR_Nem_3	44	50	PF02991	0.429
LIG_LIR_Nem_3	71	75	PF02991	0.329
LIG_LIR_Nem_3	85	89	PF02991	0.274
LIG_MLH1_MIPbox_1	169	173	PF16413	0.253
LIG_MLH1_MIPbox_1	55	59	PF16413	0.415
LIG_MYND_1	32	36	PF01753	0.377
LIG_SH2_CRK	205	209	PF00017	0.329
LIG_SH2_SRC	196	199	PF00017	0.391
LIG_SH2_STAT5	18	21	PF00017	0.654
LIG_SH2_STAT5	33	36	PF00017	0.288
LIG_SH2_STAT5	37	40	PF00017	0.210
LIG_SUMO_SIM_par_1	213	220	PF11976	0.269
LIG_TRAF2_1	62	65	PF00917	0.395
MOD_CDK_SPxxK_3	204	211	PF00069	0.259
MOD_CDK_SPxxK_3	94	101	PF00069	0.307
MOD_CK1_1	204	210	PF00069	0.295
MOD_CK1_1	41	47	PF00069	0.407
MOD_CK1_1	94	100	PF00069	0.253
MOD_CK2_1	82	88	PF00069	0.394
MOD_GlcNHglycan	12	15	PF01048	0.519
MOD_GlcNHglycan	22	25	PF01048	0.546
MOD_GSK3_1	10	17	PF00069	0.551
MOD_GSK3_1	127	134	PF00069	0.261
MOD_GSK3_1	212	219	PF00069	0.280
MOD_GSK3_1	32	39	PF00069	0.499
MOD_GSK3_1	75	82	PF00069	0.259
MOD_GSK3_1	90	97	PF00069	0.253
MOD_N-GLC_1	127	132	PF02516	0.253
MOD_N-GLC_1	167	172	PF02516	0.265
MOD_NEK2_1	173	178	PF00069	0.255
MOD_NEK2_1	19	24	PF00069	0.530
MOD_NEK2_1	3	8	PF00069	0.513
MOD_NEK2_1	75	80	PF00069	0.314
MOD_NEK2_2	131	136	PF00069	0.253
MOD_NEK2_2	54	59	PF00069	0.405
MOD_PIKK_1	167	173	PF00454	0.283
MOD_PIKK_1	60	66	PF00454	0.403
MOD_PKA_2	164	170	PF00069	0.310
MOD_PKA_2	3	9	PF00069	0.513
MOD_PKA_2	41	47	PF00069	0.462
MOD_PKA_2	90	96	PF00069	0.329
MOD_Plk_1	141	147	PF00069	0.253
MOD_Plk_1	75	81	PF00069	0.269
MOD_Plk_4	131	137	PF00069	0.278
MOD_Plk_4	14	20	PF00069	0.589
MOD_Plk_4	212	218	PF00069	0.302
MOD_Plk_4	54	60	PF00069	0.521
MOD_ProDKin_1	204	210	PF00069	0.259
MOD_ProDKin_1	32	38	PF00069	0.447
MOD_ProDKin_1	94	100	PF00069	0.301
MOD_SUMO_for_1	140	143	PF00179	0.240
MOD_SUMO_rev_2	142	149	PF00179	0.271
MOD_SUMO_rev_2	94	103	PF00179	0.309
TRG_ENDOCYTIC_2	196	199	PF00928	0.401
TRG_Pf-PMV_PEXEL_1	112	116	PF00026	0.295

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A075B759	Homo sapiens	50%	100%
A0A075B767	Homo sapiens	49%	100%
A0A0B4J2A2	Homo sapiens	51%	100%
A0A0N0P364	Leptomonas seymouri	45%	100%
A0A0N0P523	Leptomonas seymouri	59%	83%
A0A0N0P839	Leptomonas seymouri	54%	100%
A0A0N1I0P5	Leptomonas seymouri	56%	100%
A0A0N1I6E6	Leptomonas seymouri	44%	100%
A0A0N1I8P9	Leptomonas seymouri	81%	78%
A0A0N1IL84	Leptomonas seymouri	39%	72%
A0A0N1PC19	Leptomonas seymouri	37%	100%
A0A0N1PDY0	Leptomonas seymouri	30%	93%
A0A0S4IKA5	Bodo saltans	39%	75%
A0A0S4IZ55	Bodo saltans	27%	100%
A0A0S4J0W0	Bodo saltans	58%	93%
A0A0S4J378	Bodo saltans	45%	100%
A0A0S4J465	Bodo saltans	26%	94%
A0A0S4J4A4	Bodo saltans	52%	100%
A0A0S4J7K8	Bodo saltans	51%	100%
A0A0S4J8W7	Bodo saltans	42%	99%
A0A0S4J9U9	Bodo saltans	34%	100%
A0A0S4KGS8	Bodo saltans	37%	93%
A0A0S4KLH0	Bodo saltans	54%	100%
A0A1X0NJS0	Trypanosomatidae	46%	100%
A0A1X0NTQ9	Trypanosomatidae	68%	100%
A0A1X0NTS4	Trypanosomatidae	45%	99%
A0A1X0NXG7	Trypanosomatidae	61%	88%
A0A1X0P0F8	Trypanosomatidae	42%	67%
A0A1X0P184	Trypanosomatidae	57%	100%
A0A1X0P2K2	Trypanosomatidae	30%	87%
A0A1X0P4X3	Trypanosomatidae	37%	100%
A0A1X0P5F9	Trypanosomatidae	56%	100%
A0A3Q8ICB3	Leishmania donovani	45%	100%
A0A3Q8IDR1	Leishmania donovani	39%	80%
A0A3R7M7E5	Trypanosoma rangeli	37%	74%
A0A3R7MER6	Trypanosoma rangeli	43%	69%
A0A3R7MP70	Trypanosoma rangeli	39%	100%
A0A3R7NMR3	Trypanosoma rangeli	56%	100%
A0A3R7RC31	Trypanosoma rangeli	57%	100%
A0A3R7RE54	Trypanosoma rangeli	60%	89%
A0A3R7RI88	Trypanosoma rangeli	47%	100%
A0A3S5H5N2	Leishmania donovani	48%	100%
A0A3S5H7U6	Leishmania donovani	55%	100%
A0A3S5IQL2	Trypanosoma rangeli	31%	88%
A0A3S7WXF4	Leishmania donovani	59%	77%
A0A3S7WYY5	Leishmania donovani	56%	93%
A0A3S7X325	Leishmania donovani	30%	100%
A0A3S7XB52	Leishmania donovani	35%	86%
A0A422N1Z9	Trypanosoma rangeli	71%	100%
A0A422N490	Trypanosoma rangeli	45%	99%
A0A451EJ79	Leishmania donovani	36%	69%
A4FV72	Bos taurus	53%	76%
A4H346	Leishmania braziliensis	35%	68%
A4H4H8	Leishmania braziliensis	51%	100%
A4HCI8	Leishmania braziliensis	44%	100%
A4HCL8	Leishmania braziliensis	60%	77%
A4HE26	Leishmania braziliensis	58%	93%
A4HHU7	Leishmania braziliensis	30%	100%
A4HIW9	Leishmania braziliensis	86%	100%
A4HLM4	Leishmania braziliensis	56%	100%
A4HPH9	Leishmania braziliensis	39%	100%
A4HRE3	Leishmania infantum	36%	69%
A4HSQ3	Leishmania infantum	48%	100%
A4I004	Leishmania infantum	45%	100%
A4I042	Leishmania infantum	58%	77%
A4I1D2	Leishmania infantum	56%	93%
A4I4Z7	Leishmania infantum	29%	100%
A4I698	Leishmania infantum	100%	100%
A4I935	Leishmania infantum	55%	100%
A4IDA1	Leishmania infantum	35%	100%
A8X8D0	Caenorhabditis briggsae	49%	73%
B3A0R0	Lottia gigantea	47%	100%
C9ZIV0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	57%	100%
C9ZNS2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	97%
C9ZQE6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	88%
C9ZRQ0	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	68%	100%
C9ZSQ5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	43%	99%
C9ZT99	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	100%
C9ZUX8	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	57%	76%
C9ZVY5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	81%
D0A5M6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	56%	100%
D0A8E1	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	100%
D4AY02	Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371)	49%	100%
E9AC11	Leishmania major	31%	68%
E9AJA8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	69%
E9AKP0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	48%	100%
E9AT91	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	100%
E9AVX7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	45%	100%
E9AW05	Leishmania mexicana (strain MHOM/GT/2001/U1103)	58%	79%
E9AXG9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	56%	93%
E9B0C7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9B1F3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	96%	100%
E9B400	Leishmania mexicana (strain MHOM/GT/2001/U1103)	55%	100%
F5H284	Homo sapiens	50%	100%
O00060	Uromyces fabae	54%	100%
O00845	Paramecium primaurelia	51%	100%
O02614	Leishmania major	55%	93%
O43447	Homo sapiens	49%	100%
O49605	Arabidopsis thaliana	45%	100%
O49886	Lupinus luteus	56%	100%
O53021	Dickeya dadantii (strain 3937)	29%	100%
O74729	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	48%	100%
O93826	Arthroderma benhamiae	49%	100%
O94273	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	51%	100%
P0C1H7	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	55%	100%
P0C1H8	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	53%	100%
P0C1H9	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	50%	100%
P0C1I0	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	48%	100%
P0C1I2	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	54%	73%
P0C1I3	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	51%	100%
P0C1I7	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	56%	100%
P0C1I8	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	54%	100%
P0C1I9	Rhizopus delemar (strain RA 99-880 / ATCC MYA-4621 / FGSC 9543 / NRRL 43880)	49%	68%
P0CP78	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	48%	99%
P0CP79	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	48%	99%
P0CP82	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	48%	100%
P0CP83	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	48%	100%
P0CP86	Cryptococcus neoformans var. neoformans serotype D (strain JEC21 / ATCC MYA-565)	40%	100%
P0CP87	Cryptococcus neoformans var. neoformans serotype D (strain B-3501A)	40%	100%
P0DN26	Homo sapiens	50%	100%
P0DN37	Homo sapiens	50%	100%
P10111	Rattus norvegicus	56%	100%
P10255	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	51%	100%
P14088	Echinococcus granulosus	54%	100%
P14832	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	54%	100%
P14851	Cricetulus griseus	56%	100%
P15425	Drosophila melanogaster	42%	97%
P17742	Mus musculus	56%	100%
P18253	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	55%	100%
P21568	Solanum lycopersicum	57%	100%
P21569	Zea mays	57%	100%
P22011	Candida albicans (strain SC5314 / ATCC MYA-2876)	54%	100%
P23284	Homo sapiens	46%	100%
P23285	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	42%	100%
P24367	Gallus gallus	50%	100%
P24368	Rattus norvegicus	46%	100%
P24369	Mus musculus	45%	100%
P24525	Brassica napus	56%	100%
P25007	Drosophila melanogaster	55%	100%
P25334	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	33%	72%
P25719	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	56%	100%
P28517	Calliphora vicina	43%	98%
P29117	Rattus norvegicus	54%	100%
P30404	Bos taurus	55%	100%
P30405	Homo sapiens	54%	100%
P30412	Mus musculus	46%	100%
P34790	Arabidopsis thaliana	56%	100%
P34791	Arabidopsis thaliana	55%	88%
P35176	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	51%	100%
P35627	Unspecified eudicot DB-1992	57%	100%
P42693	Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)	29%	100%
P45877	Homo sapiens	41%	100%
P52009	Caenorhabditis elegans	58%	100%
P52010	Caenorhabditis elegans	54%	100%
P52011	Caenorhabditis elegans	58%	100%
P52013	Caenorhabditis elegans	51%	100%
P52014	Caenorhabditis elegans	44%	100%
P52015	Caenorhabditis elegans	57%	100%
P52018	Caenorhabditis elegans	53%	100%
P54985	Blattella germanica	54%	100%
P62935	Bos taurus	55%	100%
P62936	Sus scrofa	55%	100%
P62937	Homo sapiens	55%	100%
P62938	Chlorocebus aethiops	55%	100%
P62940	Macaca mulatta	55%	100%
P62941	Papio anubis	55%	100%
P65763	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	35%	100%
P73789	Synechocystis sp. (strain PCC 6803 / Kazusa)	53%	100%
P80311	Bos taurus	46%	100%
P84343	Neospora caninum	48%	100%
P91791	Hemicentrotus pulcherrimus	56%	100%
P9WHW2	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	35%	100%
P9WHW3	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	35%	100%
Q01490	Orpinomyces sp. (strain PC-2)	48%	100%
Q06118	Streptomyces anulatus	49%	100%
Q08E11	Bos taurus	45%	100%
Q09637	Caenorhabditis elegans	47%	74%
Q0P5D0	Bos taurus	49%	100%
Q0ZQK3	Saguinus oedipus	56%	100%
Q0ZQK6	Symphalangus syndactylus	55%	100%
Q0ZQK7	Nomascus leucogenys	55%	100%
Q0ZQK8	Hylobates lar	55%	100%
Q0ZQL0	Gorilla gorilla gorilla	55%	100%
Q0ZQL1	Pan troglodytes	55%	100%
Q0ZQL2	Pan paniscus	55%	100%
Q1RMP7	Bos taurus	38%	75%
Q26516	Schistosoma japonicum	53%	100%
Q26548	Schistosoma mansoni	48%	84%
Q26551	Schistosoma mansoni	49%	100%
Q26565	Schistosoma mansoni	55%	100%
Q27774	Schistosoma japonicum	45%	100%
Q2FIC1	Staphylococcus aureus (strain USA300)	36%	100%
Q2FZU9	Staphylococcus aureus (strain NCTC 8325 / PS 47)	36%	100%
Q2TZ33	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	51%	100%
Q2U6U0	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	44%	100%
Q2UGK2	Aspergillus oryzae (strain ATCC 42149 / RIB 40)	47%	100%
Q2YWT2	Staphylococcus aureus (strain bovine RF122 / ET3-1)	36%	100%
Q38867	Arabidopsis thaliana	56%	100%
Q38900	Arabidopsis thaliana	57%	100%
Q39613	Catharanthus roseus	58%	100%
Q41651	Vicia faba	57%	92%
Q42406	Arabidopsis thaliana	59%	100%
Q49W93	Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)	35%	100%
Q4G338	Haemonchus contortus	57%	71%
Q4I1Y1	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	43%	100%
Q4I5R9	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	51%	92%
Q4IPB8	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	38%	100%
Q4IPH4	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	54%	100%
Q4L4W9	Staphylococcus haemolyticus (strain JCSC1435)	36%	100%
Q4P6X6	Ustilago maydis (strain 521 / FGSC 9021)	50%	100%
Q4Q1A6	Leishmania major	35%	100%
Q4Q424	Leishmania major	55%	100%
Q4Q6Q9	Leishmania major	99%	100%
Q4Q7V7	Leishmania major	29%	100%
Q4QBH1	Leishmania major	59%	78%
Q4QBK2	Leishmania major	45%	100%
Q4QJ67	Leishmania major	48%	100%
Q4WCM6	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	52%	100%
Q4WCR3	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	44%	100%
Q4WMB6	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	37%	100%
Q4WP12	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	50%	100%
Q54SM3	Dictyostelium discoideum	53%	100%
Q5AQL0	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	52%	100%
Q5ASQ0	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	43%	100%
Q5B4R3	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	45%	100%
Q5BAH7	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	36%	100%
Q5HHD1	Staphylococcus aureus (strain COL)	36%	100%
Q5HQK8	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	37%	100%
Q5R723	Pongo abelii	53%	76%
Q5R8S7	Pongo pygmaeus	55%	100%
Q5UP71	Acanthamoeba polyphaga mimivirus	27%	98%
Q5ZLV2	Gallus gallus	41%	100%
Q6C4W6	Yarrowia lipolytica (strain CLIB 122 / E 150)	48%	100%
Q6DTV9	Aotus trivirgatus	56%	100%
Q6GAX2	Staphylococcus aureus (strain MSSA476)	36%	100%
Q6GID4	Staphylococcus aureus (strain MRSA252)	36%	100%
Q7A1C0	Staphylococcus aureus (strain MW2)	36%	100%
Q7A6I1	Staphylococcus aureus (strain N315)	36%	100%
Q7S7Z6	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	49%	80%
Q7SF72	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	44%	100%
Q7SG06	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	54%	100%
Q812D3	Rattus norvegicus	41%	100%
Q8CT84	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	37%	100%
Q8HXS3	Felis catus	55%	100%
Q8IXY8	Homo sapiens	41%	74%
Q8L8W5	Arabidopsis thaliana	52%	100%
Q8LDP4	Arabidopsis thaliana	53%	100%
Q8SRE1	Encephalitozoon cuniculi (strain GB-M1)	51%	100%
Q8W171	Glycine max	56%	100%
Q8X166	Aspergillus niger	47%	100%
Q8X191	Aspergillus niger	43%	100%
Q99KR7	Mus musculus	54%	100%
Q99VD4	Staphylococcus aureus (strain Mu50 / ATCC 700699)	36%	100%
Q9ASS6	Arabidopsis thaliana	54%	88%
Q9D6D8	Mus musculus	40%	73%
Q9D6L8	Mus musculus	40%	100%
Q9D868	Mus musculus	49%	100%
Q9H2H8	Homo sapiens	41%	100%
Q9LIK6	Arabidopsis thaliana	40%	99%
Q9LPC7	Arabidopsis thaliana	44%	100%
Q9NI62	Dictyostelium discoideum	46%	100%
Q9QZH3	Mus musculus	53%	76%
Q9SIH1	Arabidopsis thaliana	46%	100%
Q9SKQ0	Arabidopsis thaliana	57%	100%
Q9SP02	Arabidopsis thaliana	50%	100%
Q9TTC6	Oryctolagus cuniculus	56%	100%
Q9TW32	Dictyostelium discoideum	53%	100%
Q9UA41	Dictyostelium discoideum	51%	100%
Q9UNP9	Homo sapiens	53%	76%
Q9V3G3	Drosophila melanogaster	46%	76%
Q9Y536	Homo sapiens	50%	100%
Q9ZVJ4	Arabidopsis thaliana	49%	100%
V5B2A0	Trypanosoma cruzi	59%	89%
V5B9Y6	Trypanosoma cruzi	40%	74%
V5BGX2	Trypanosoma cruzi	30%	86%
V5BHF5	Trypanosoma cruzi	57%	100%
V5D532	Trypanosoma cruzi	45%	100%
V5DJ29	Trypanosoma cruzi	42%	71%