LeishMANIAdb
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PhoLip_ATPase_C domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
PhoLip_ATPase_C domain-containing protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7X3X3_LEIDO
TriTrypDb:
LdBPK_303320.1 , LdCL_300038800 , LDHU3_30.4410
Length:
165

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 9
GO:0110165 cellular anatomical entity 1 9
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Expansion

Sequence features

A0A3S7X3X3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X3X3

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_PCSK_KEX2_1 95 97 PF00082 0.449
CLV_PCSK_PC1ET2_1 95 97 PF00082 0.430
CLV_PCSK_PC7_1 91 97 PF00082 0.410
CLV_PCSK_SKI1_1 111 115 PF00082 0.400
CLV_PCSK_SKI1_1 2 6 PF00082 0.429
DEG_Nend_UBRbox_1 1 4 PF02207 0.597
DOC_CDC14_PxL_1 54 62 PF14671 0.496
DOC_MAPK_gen_1 25 35 PF00069 0.500
DOC_MAPK_MEF2A_6 111 120 PF00069 0.564
DOC_MAPK_MEF2A_6 72 81 PF00069 0.325
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1I2K3 Leptomonas seymouri 80% 100%
A0A1X0P2W0 Trypanosomatidae 49% 100%
A0A3R7N1L0 Trypanosoma rangeli 51% 100%
A4HIR6 Leishmania braziliensis 93% 100%
A4I611 Leishmania infantum 100% 100%
C9ZRD6 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 44% 81%
E9B1A2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%
Q4Q6W2 Leishmania major 96% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS