LeishMANIAdb
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Protein kinase-like protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Protein kinase-like protein
Gene product:
protein kinase-like protein
Species:
Leishmania donovani
UniProt:
A0A3S7X3R8_LEIDO
TriTrypDb:
LdBPK_303090.1 * , LdCL_300036500 , LDHU3_30.4100
Length:
1900

Annotations

LeishMANIAdb annotations

Contains several domains (including N-terminal, extracellular sensor domains) fused to a C-terminal STE11-type protein kinase domain. . The C-terminal TM domain preceding the kinase domain seemingly evolved de novo, with an ancertain number of TM segments (but odd in number).. Localization: Cell surface (by feature)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 2, no: 7
NetGPI no yes: 0, no: 9
Cellular components
Term Name Level Count
GO:0016020 membrane 2 9
GO:0110165 cellular anatomical entity 1 9
GO:0005737 cytoplasm 2 1

Expansion

Sequence features

A0A3S7X3R8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0006468 protein phosphorylation 5 9
GO:0006793 phosphorus metabolic process 3 9
GO:0006796 phosphate-containing compound metabolic process 4 9
GO:0006807 nitrogen compound metabolic process 2 9
GO:0008152 metabolic process 1 9
GO:0009987 cellular process 1 9
GO:0016310 phosphorylation 5 9
GO:0019538 protein metabolic process 3 9
GO:0036211 protein modification process 4 9
GO:0043170 macromolecule metabolic process 3 9
GO:0043412 macromolecule modification 4 9
GO:0044237 cellular metabolic process 2 9
GO:0044238 primary metabolic process 2 9
GO:0071704 organic substance metabolic process 2 9
GO:1901564 organonitrogen compound metabolic process 3 9
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 9
GO:0003824 catalytic activity 1 10
GO:0004672 protein kinase activity 3 9
GO:0005488 binding 1 9
GO:0005524 ATP binding 5 9
GO:0016301 kinase activity 4 9
GO:0016740 transferase activity 2 10
GO:0016772 transferase activity, transferring phosphorus-containing groups 3 9
GO:0016773 phosphotransferase activity, alcohol group as acceptor 4 9
GO:0017076 purine nucleotide binding 4 9
GO:0030554 adenyl nucleotide binding 5 9
GO:0032553 ribonucleotide binding 3 9
GO:0032555 purine ribonucleotide binding 4 9
GO:0032559 adenyl ribonucleotide binding 5 9
GO:0035639 purine ribonucleoside triphosphate binding 4 9
GO:0036094 small molecule binding 2 9
GO:0043167 ion binding 2 9
GO:0043168 anion binding 3 9
GO:0097159 organic cyclic compound binding 2 9
GO:0097367 carbohydrate derivative binding 2 9
GO:0140096 catalytic activity, acting on a protein 2 9
GO:1901265 nucleoside phosphate binding 3 9
GO:1901363 heterocyclic compound binding 2 9
GO:0004674 protein serine/threonine kinase activity 4 2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 1257 1261 PF00656 0.446
CLV_C14_Caspase3-7 14 18 PF00656 0.392
CLV_C14_Caspase3-7 1831 1835 PF00656 0.686
CLV_C14_Caspase3-7 577 581 PF00656 0.421
CLV_C14_Caspase3-7 767 771 PF00656 0.313
CLV_MEL_PAP_1 923 929 PF00089 0.450
CLV_NRD_NRD_1 1041 1043 PF00675 0.620
CLV_NRD_NRD_1 1066 1068 PF00675 0.573
CLV_NRD_NRD_1 1088 1090 PF00675 0.584
CLV_NRD_NRD_1 119 121 PF00675 0.609
CLV_NRD_NRD_1 1197 1199 PF00675 0.536
CLV_NRD_NRD_1 1227 1229 PF00675 0.328
CLV_NRD_NRD_1 236 238 PF00675 0.617
CLV_NRD_NRD_1 528 530 PF00675 0.603
CLV_NRD_NRD_1 732 734 PF00675 0.504
CLV_NRD_NRD_1 873 875 PF00675 0.630
CLV_NRD_NRD_1 94 96 PF00675 0.647
CLV_PCSK_KEX2_1 1043 1045 PF00082 0.608
CLV_PCSK_KEX2_1 1066 1068 PF00082 0.571
CLV_PCSK_KEX2_1 1088 1090 PF00082 0.584
CLV_PCSK_KEX2_1 119 121 PF00082 0.609
CLV_PCSK_KEX2_1 1216 1218 PF00082 0.354
CLV_PCSK_KEX2_1 1226 1228 PF00082 0.284
CLV_PCSK_KEX2_1 1807 1809 PF00082 0.308
CLV_PCSK_KEX2_1 236 238 PF00082 0.617
CLV_PCSK_KEX2_1 370 372 PF00082 0.555
CLV_PCSK_KEX2_1 528 530 PF00082 0.603
CLV_PCSK_KEX2_1 732 734 PF00082 0.568
CLV_PCSK_KEX2_1 873 875 PF00082 0.630
CLV_PCSK_KEX2_1 94 96 PF00082 0.590
CLV_PCSK_PC1ET2_1 1043 1045 PF00082 0.638
CLV_PCSK_PC1ET2_1 1216 1218 PF00082 0.378
CLV_PCSK_PC1ET2_1 1807 1809 PF00082 0.308
CLV_PCSK_PC1ET2_1 370 372 PF00082 0.573
CLV_PCSK_PC7_1 1803 1809 PF00082 0.308
CLV_PCSK_SKI1_1 1043 1047 PF00082 0.605
CLV_PCSK_SKI1_1 120 124 PF00082 0.618
CLV_PCSK_SKI1_1 1355 1359 PF00082 0.372
CLV_PCSK_SKI1_1 1427 1431 PF00082 0.365
CLV_PCSK_SKI1_1 148 152 PF00082 0.605
CLV_PCSK_SKI1_1 1504 1508 PF00082 0.340
CLV_PCSK_SKI1_1 1649 1653 PF00082 0.331
CLV_PCSK_SKI1_1 1681 1685 PF00082 0.322
CLV_PCSK_SKI1_1 1794 1798 PF00082 0.308
CLV_PCSK_SKI1_1 194 198 PF00082 0.583
CLV_PCSK_SKI1_1 250 254 PF00082 0.583
CLV_PCSK_SKI1_1 556 560 PF00082 0.596
CLV_PCSK_SKI1_1 607 611 PF00082 0.534
CLV_PCSK_SKI1_1 648 652 PF00082 0.605
CLV_PCSK_SKI1_1 733 737 PF00082 0.622
CLV_PCSK_SKI1_1 753 757 PF00082 0.364
CLV_PCSK_SKI1_1 792 796 PF00082 0.567
CLV_PCSK_SKI1_1 821 825 PF00082 0.574
DEG_APCC_DBOX_1 606 614 PF00400 0.362
DEG_APCC_DBOX_1 731 739 PF00400 0.295
DEG_MDM2_SWIB_1 1422 1430 PF02201 0.446
DEG_Nend_Nbox_1 1 3 PF02207 0.373
DEG_SPOP_SBC_1 222 226 PF00917 0.337
DOC_CKS1_1 1124 1129 PF01111 0.446
DOC_CKS1_1 1363 1368 PF01111 0.513
DOC_CYCLIN_yCln2_LP_2 1360 1366 PF00134 0.409
DOC_CYCLIN_yCln2_LP_2 1378 1384 PF00134 0.180
DOC_MAPK_gen_1 1066 1072 PF00069 0.374
DOC_MAPK_gen_1 1088 1096 PF00069 0.353
DOC_MAPK_gen_1 1226 1235 PF00069 0.554
DOC_MAPK_gen_1 1314 1322 PF00069 0.515
DOC_MAPK_gen_1 1455 1463 PF00069 0.609
DOC_MAPK_gen_1 1681 1690 PF00069 0.508
DOC_MAPK_gen_1 193 199 PF00069 0.394
DOC_MAPK_HePTP_8 702 714 PF00069 0.366
DOC_MAPK_MEF2A_6 1125 1134 PF00069 0.518
DOC_MAPK_MEF2A_6 1316 1324 PF00069 0.505
DOC_MAPK_MEF2A_6 1372 1379 PF00069 0.522
DOC_MAPK_MEF2A_6 380 389 PF00069 0.362
DOC_MAPK_MEF2A_6 705 714 PF00069 0.362
DOC_MAPK_MEF2A_6 910 919 PF00069 0.406
DOC_MAPK_MEF2A_6 920 927 PF00069 0.372
DOC_MAPK_NFAT4_5 1372 1380 PF00069 0.536
DOC_MAPK_RevD_3 1200 1216 PF00069 0.485
DOC_PP1_RVXF_1 1353 1359 PF00149 0.436
DOC_PP1_RVXF_1 139 145 PF00149 0.364
DOC_PP1_RVXF_1 1425 1432 PF00149 0.565
DOC_PP1_RVXF_1 359 365 PF00149 0.337
DOC_PP1_RVXF_1 688 694 PF00149 0.363
DOC_PP2B_LxvP_1 1168 1171 PF13499 0.331
DOC_PP2B_LxvP_1 1185 1188 PF13499 0.229
DOC_PP2B_LxvP_1 158 161 PF13499 0.328
DOC_PP2B_LxvP_1 477 480 PF13499 0.400
DOC_PP4_FxxP_1 1250 1253 PF00568 0.344
DOC_PP4_FxxP_1 6 9 PF00568 0.437
DOC_PP4_FxxP_1 795 798 PF00568 0.286
DOC_PP4_FxxP_1 859 862 PF00568 0.290
DOC_SPAK_OSR1_1 1151 1155 PF12202 0.408
DOC_USP7_MATH_1 1171 1175 PF00917 0.390
DOC_USP7_MATH_1 1253 1257 PF00917 0.369
DOC_USP7_MATH_1 153 157 PF00917 0.406
DOC_USP7_MATH_1 1600 1604 PF00917 0.547
DOC_USP7_MATH_1 1711 1715 PF00917 0.591
DOC_USP7_MATH_1 1787 1791 PF00917 0.466
DOC_USP7_MATH_1 1824 1828 PF00917 0.664
DOC_USP7_MATH_1 1829 1833 PF00917 0.650
DOC_USP7_MATH_1 1864 1868 PF00917 0.759
DOC_USP7_MATH_1 1884 1888 PF00917 0.542
DOC_USP7_MATH_1 222 226 PF00917 0.337
DOC_USP7_MATH_1 421 425 PF00917 0.363
DOC_USP7_MATH_1 511 515 PF00917 0.388
DOC_USP7_MATH_1 621 625 PF00917 0.321
DOC_USP7_MATH_1 746 750 PF00917 0.349
DOC_USP7_MATH_1 878 882 PF00917 0.460
DOC_WW_Pin1_4 1123 1128 PF00397 0.501
DOC_WW_Pin1_4 1189 1194 PF00397 0.413
DOC_WW_Pin1_4 131 136 PF00397 0.450
DOC_WW_Pin1_4 1362 1367 PF00397 0.496
DOC_WW_Pin1_4 1541 1546 PF00397 0.657
DOC_WW_Pin1_4 1594 1599 PF00397 0.561
DOC_WW_Pin1_4 1721 1726 PF00397 0.508
DOC_WW_Pin1_4 1841 1846 PF00397 0.644
DOC_WW_Pin1_4 1860 1865 PF00397 0.534
DOC_WW_Pin1_4 1870 1875 PF00397 0.770
DOC_WW_Pin1_4 266 271 PF00397 0.418
DOC_WW_Pin1_4 380 385 PF00397 0.375
DOC_WW_Pin1_4 403 408 PF00397 0.419
DOC_WW_Pin1_4 890 895 PF00397 0.413
LIG_14-3-3_CanoR_1 1004 1013 PF00244 0.463
LIG_14-3-3_CanoR_1 1448 1458 PF00244 0.582
LIG_14-3-3_CanoR_1 1808 1815 PF00244 0.508
LIG_14-3-3_CanoR_1 361 365 PF00244 0.369
LIG_14-3-3_CanoR_1 437 442 PF00244 0.383
LIG_14-3-3_CanoR_1 475 480 PF00244 0.345
LIG_14-3-3_CanoR_1 493 497 PF00244 0.376
LIG_14-3-3_CanoR_1 50 56 PF00244 0.459
LIG_14-3-3_CanoR_1 607 613 PF00244 0.339
LIG_14-3-3_CanoR_1 732 736 PF00244 0.420
LIG_14-3-3_CanoR_1 753 758 PF00244 0.358
LIG_14-3-3_CanoR_1 774 784 PF00244 0.316
LIG_14-3-3_CanoR_1 815 819 PF00244 0.375
LIG_14-3-3_CanoR_1 873 877 PF00244 0.424
LIG_14-3-3_CanoR_1 892 898 PF00244 0.321
LIG_14-3-3_CanoR_1 910 917 PF00244 0.292
LIG_14-3-3_CanoR_1 926 932 PF00244 0.336
LIG_14-3-3_CanoR_1 956 960 PF00244 0.428
LIG_Actin_WH2_2 1255 1271 PF00022 0.447
LIG_Actin_WH2_2 1835 1850 PF00022 0.629
LIG_Actin_WH2_2 959 977 PF00022 0.299
LIG_AP2alpha_1 351 355 PF02296 0.367
LIG_AP2alpha_2 187 189 PF02296 0.383
LIG_AP2alpha_2 788 790 PF02296 0.371
LIG_APCC_ABBA_1 1307 1312 PF00400 0.497
LIG_APCC_ABBA_1 1632 1637 PF00400 0.508
LIG_APCC_ABBA_1 856 861 PF00400 0.412
LIG_APCC_ABBAyCdc20_2 1676 1682 PF00400 0.508
LIG_BRCT_BRCA1_1 1317 1321 PF00533 0.444
LIG_BRCT_BRCA1_1 1770 1774 PF00533 0.561
LIG_BRCT_BRCA1_1 1832 1836 PF00533 0.690
LIG_BRCT_BRCA1_1 1895 1899 PF00533 0.537
LIG_CaM_IQ_9 1449 1464 PF13499 0.611
LIG_Clathr_ClatBox_1 1552 1556 PF01394 0.659
LIG_Clathr_ClatBox_1 1633 1637 PF01394 0.531
LIG_deltaCOP1_diTrp_1 1090 1097 PF00928 0.391
LIG_deltaCOP1_diTrp_1 1759 1766 PF00928 0.561
LIG_deltaCOP1_diTrp_1 848 856 PF00928 0.379
LIG_EH1_1 1151 1159 PF00400 0.421
LIG_EH1_1 1239 1247 PF00400 0.391
LIG_FHA_1 1103 1109 PF00498 0.416
LIG_FHA_1 1271 1277 PF00498 0.383
LIG_FHA_1 1437 1443 PF00498 0.570
LIG_FHA_1 1497 1503 PF00498 0.558
LIG_FHA_1 153 159 PF00498 0.399
LIG_FHA_1 1572 1578 PF00498 0.508
LIG_FHA_1 1629 1635 PF00498 0.551
LIG_FHA_1 1643 1649 PF00498 0.481
LIG_FHA_1 1653 1659 PF00498 0.504
LIG_FHA_1 1661 1667 PF00498 0.426
LIG_FHA_1 1777 1783 PF00498 0.508
LIG_FHA_1 1870 1876 PF00498 0.745
LIG_FHA_1 331 337 PF00498 0.405
LIG_FHA_1 389 395 PF00498 0.320
LIG_FHA_1 472 478 PF00498 0.379
LIG_FHA_1 486 492 PF00498 0.409
LIG_FHA_1 507 513 PF00498 0.327
LIG_FHA_1 52 58 PF00498 0.374
LIG_FHA_1 580 586 PF00498 0.419
LIG_FHA_1 642 648 PF00498 0.305
LIG_FHA_1 654 660 PF00498 0.290
LIG_FHA_1 754 760 PF00498 0.370
LIG_FHA_1 78 84 PF00498 0.345
LIG_FHA_1 853 859 PF00498 0.413
LIG_FHA_1 910 916 PF00498 0.375
LIG_FHA_1 920 926 PF00498 0.338
LIG_FHA_1 928 934 PF00498 0.292
LIG_FHA_1 947 953 PF00498 0.406
LIG_FHA_2 1052 1058 PF00498 0.432
LIG_FHA_2 1085 1091 PF00498 0.414
LIG_FHA_2 1133 1139 PF00498 0.567
LIG_FHA_2 1509 1515 PF00498 0.604
LIG_FHA_2 1625 1631 PF00498 0.531
LIG_FHA_2 1738 1744 PF00498 0.508
LIG_FHA_2 1748 1754 PF00498 0.508
LIG_FHA_2 225 231 PF00498 0.461
LIG_FHA_2 327 333 PF00498 0.384
LIG_FHA_2 916 922 PF00498 0.378
LIG_GBD_Chelix_1 1175 1183 PF00786 0.597
LIG_GBD_Chelix_1 1235 1243 PF00786 0.322
LIG_GBD_Chelix_1 1283 1291 PF00786 0.344
LIG_GBD_Chelix_1 1386 1394 PF00786 0.310
LIG_LIR_Apic_2 146 152 PF02991 0.381
LIG_LIR_Apic_2 1724 1730 PF02991 0.508
LIG_LIR_Apic_2 5 9 PF02991 0.435
LIG_LIR_Apic_2 739 744 PF02991 0.376
LIG_LIR_Apic_2 793 798 PF02991 0.285
LIG_LIR_Gen_1 1090 1100 PF02991 0.321
LIG_LIR_Gen_1 1105 1112 PF02991 0.264
LIG_LIR_Gen_1 1133 1144 PF02991 0.548
LIG_LIR_Gen_1 1148 1157 PF02991 0.289
LIG_LIR_Gen_1 1273 1281 PF02991 0.383
LIG_LIR_Gen_1 1289 1298 PF02991 0.379
LIG_LIR_Gen_1 1318 1328 PF02991 0.485
LIG_LIR_Gen_1 1420 1430 PF02991 0.392
LIG_LIR_Gen_1 166 176 PF02991 0.383
LIG_LIR_Gen_1 1663 1672 PF02991 0.508
LIG_LIR_Gen_1 1764 1774 PF02991 0.508
LIG_LIR_Gen_1 1833 1842 PF02991 0.688
LIG_LIR_Gen_1 195 202 PF02991 0.376
LIG_LIR_Gen_1 242 252 PF02991 0.388
LIG_LIR_Gen_1 286 295 PF02991 0.415
LIG_LIR_Gen_1 383 394 PF02991 0.332
LIG_LIR_Gen_1 462 472 PF02991 0.414
LIG_LIR_Gen_1 547 558 PF02991 0.370
LIG_LIR_Gen_1 700 707 PF02991 0.355
LIG_LIR_Gen_1 846 856 PF02991 0.380
LIG_LIR_LC3C_4 947 952 PF02991 0.406
LIG_LIR_Nem_3 1090 1096 PF02991 0.321
LIG_LIR_Nem_3 1105 1109 PF02991 0.264
LIG_LIR_Nem_3 1133 1139 PF02991 0.544
LIG_LIR_Nem_3 1140 1144 PF02991 0.503
LIG_LIR_Nem_3 1148 1152 PF02991 0.296
LIG_LIR_Nem_3 117 121 PF02991 0.416
LIG_LIR_Nem_3 1210 1214 PF02991 0.376
LIG_LIR_Nem_3 1280 1285 PF02991 0.346
LIG_LIR_Nem_3 1318 1324 PF02991 0.460
LIG_LIR_Nem_3 1331 1337 PF02991 0.315
LIG_LIR_Nem_3 1365 1370 PF02991 0.504
LIG_LIR_Nem_3 1407 1413 PF02991 0.287
LIG_LIR_Nem_3 1420 1425 PF02991 0.311
LIG_LIR_Nem_3 1460 1466 PF02991 0.556
LIG_LIR_Nem_3 1571 1575 PF02991 0.512
LIG_LIR_Nem_3 166 171 PF02991 0.375
LIG_LIR_Nem_3 1663 1667 PF02991 0.508
LIG_LIR_Nem_3 1764 1769 PF02991 0.508
LIG_LIR_Nem_3 1795 1801 PF02991 0.511
LIG_LIR_Nem_3 1833 1839 PF02991 0.696
LIG_LIR_Nem_3 195 199 PF02991 0.372
LIG_LIR_Nem_3 242 247 PF02991 0.343
LIG_LIR_Nem_3 277 283 PF02991 0.332
LIG_LIR_Nem_3 286 292 PF02991 0.309
LIG_LIR_Nem_3 363 368 PF02991 0.387
LIG_LIR_Nem_3 38 43 PF02991 0.357
LIG_LIR_Nem_3 383 389 PF02991 0.286
LIG_LIR_Nem_3 462 467 PF02991 0.427
LIG_LIR_Nem_3 547 553 PF02991 0.370
LIG_LIR_Nem_3 700 704 PF02991 0.355
LIG_LIR_Nem_3 846 852 PF02991 0.357
LIG_LIR_Nem_3 855 859 PF02991 0.366
LIG_NRBOX 1036 1042 PF00104 0.397
LIG_NRBOX 1355 1361 PF00104 0.393
LIG_NRBOX 693 699 PF00104 0.312
LIG_PCNA_yPIPBox_3 956 964 PF02747 0.463
LIG_Pex14_1 1093 1097 PF04695 0.446
LIG_Pex14_1 1113 1117 PF04695 0.357
LIG_Pex14_1 1207 1211 PF04695 0.444
LIG_Pex14_1 1220 1224 PF04695 0.564
LIG_Pex14_1 1334 1338 PF04695 0.309
LIG_Pex14_1 1762 1766 PF04695 0.508
LIG_Pex14_2 1203 1207 PF04695 0.364
LIG_Pex14_2 1346 1350 PF04695 0.444
LIG_Pex14_2 1358 1362 PF04695 0.455
LIG_Pex14_2 1422 1426 PF04695 0.425
LIG_Pex14_2 351 355 PF04695 0.343
LIG_Pex14_2 364 368 PF04695 0.361
LIG_PTB_Apo_2 1244 1251 PF02174 0.444
LIG_PTB_Apo_2 1301 1308 PF02174 0.442
LIG_PTB_Apo_2 1344 1351 PF02174 0.395
LIG_PTB_Apo_2 676 683 PF02174 0.397
LIG_REV1ctd_RIR_1 187 198 PF16727 0.380
LIG_SH2_CRK 1079 1083 PF00017 0.391
LIG_SH2_CRK 1141 1145 PF00017 0.537
LIG_SH2_CRK 1240 1244 PF00017 0.429
LIG_SH2_CRK 1338 1342 PF00017 0.362
LIG_SH2_CRK 1367 1371 PF00017 0.502
LIG_SH2_CRK 1572 1576 PF00017 0.508
LIG_SH2_CRK 244 248 PF00017 0.386
LIG_SH2_CRK 40 44 PF00017 0.359
LIG_SH2_CRK 464 468 PF00017 0.420
LIG_SH2_CRK 505 509 PF00017 0.355
LIG_SH2_CRK 550 554 PF00017 0.370
LIG_SH2_CRK 741 745 PF00017 0.390
LIG_SH2_CRK 935 939 PF00017 0.343
LIG_SH2_GRB2like 1528 1531 PF00017 0.728
LIG_SH2_GRB2like 1590 1593 PF00017 0.551
LIG_SH2_NCK_1 1079 1083 PF00017 0.391
LIG_SH2_NCK_1 1141 1145 PF00017 0.561
LIG_SH2_NCK_1 298 302 PF00017 0.441
LIG_SH2_NCK_1 464 468 PF00017 0.420
LIG_SH2_PTP2 1391 1394 PF00017 0.357
LIG_SH2_PTP2 1590 1593 PF00017 0.531
LIG_SH2_PTP2 386 389 PF00017 0.338
LIG_SH2_SRC 1079 1082 PF00017 0.420
LIG_SH2_SRC 1590 1593 PF00017 0.551
LIG_SH2_STAP1 1662 1666 PF00017 0.508
LIG_SH2_STAP1 1770 1774 PF00017 0.508
LIG_SH2_STAP1 472 476 PF00017 0.377
LIG_SH2_STAT3 1662 1665 PF00017 0.508
LIG_SH2_STAT5 1115 1118 PF00017 0.594
LIG_SH2_STAT5 1146 1149 PF00017 0.339
LIG_SH2_STAT5 1204 1207 PF00017 0.420
LIG_SH2_STAT5 1213 1216 PF00017 0.410
LIG_SH2_STAT5 1224 1227 PF00017 0.572
LIG_SH2_STAT5 1231 1234 PF00017 0.434
LIG_SH2_STAT5 1240 1243 PF00017 0.269
LIG_SH2_STAT5 1385 1388 PF00017 0.403
LIG_SH2_STAT5 1391 1394 PF00017 0.340
LIG_SH2_STAT5 1400 1403 PF00017 0.233
LIG_SH2_STAT5 1488 1491 PF00017 0.576
LIG_SH2_STAT5 1590 1593 PF00017 0.508
LIG_SH2_STAT5 1622 1625 PF00017 0.516
LIG_SH2_STAT5 1662 1665 PF00017 0.504
LIG_SH2_STAT5 1672 1675 PF00017 0.514
LIG_SH2_STAT5 1775 1778 PF00017 0.508
LIG_SH2_STAT5 244 247 PF00017 0.341
LIG_SH2_STAT5 280 283 PF00017 0.391
LIG_SH2_STAT5 386 389 PF00017 0.351
LIG_SH2_STAT5 445 448 PF00017 0.371
LIG_SH2_STAT5 809 812 PF00017 0.373
LIG_SH2_STAT5 890 893 PF00017 0.373
LIG_SH2_STAT5 993 996 PF00017 0.383
LIG_SH3_2 1363 1368 PF14604 0.592
LIG_SH3_3 1019 1025 PF00018 0.528
LIG_SH3_3 1163 1169 PF00018 0.318
LIG_SH3_3 1292 1298 PF00018 0.444
LIG_SH3_3 1360 1366 PF00018 0.445
LIG_SH3_3 158 164 PF00018 0.302
LIG_SH3_3 1719 1725 PF00018 0.531
LIG_SH3_3 1780 1786 PF00018 0.508
LIG_SH3_3 1839 1845 PF00018 0.620
LIG_SH3_3 1878 1884 PF00018 0.729
LIG_SH3_3 278 284 PF00018 0.438
LIG_SH3_3 297 303 PF00018 0.397
LIG_SH3_3 56 62 PF00018 0.417
LIG_SH3_3 805 811 PF00018 0.410
LIG_SH3_3 825 831 PF00018 0.195
LIG_SH3_3 888 894 PF00018 0.418
LIG_SH3_3 949 955 PF00018 0.409
LIG_SUMO_SIM_anti_2 1241 1247 PF11976 0.444
LIG_SUMO_SIM_anti_2 563 568 PF11976 0.404
LIG_SUMO_SIM_anti_2 608 614 PF11976 0.349
LIG_SUMO_SIM_anti_2 656 663 PF11976 0.381
LIG_SUMO_SIM_anti_2 66 73 PF11976 0.357
LIG_SUMO_SIM_anti_2 900 907 PF11976 0.402
LIG_SUMO_SIM_par_1 1391 1397 PF11976 0.441
LIG_SUMO_SIM_par_1 1551 1557 PF11976 0.646
LIG_SUMO_SIM_par_1 332 339 PF11976 0.320
LIG_SUMO_SIM_par_1 390 395 PF11976 0.314
LIG_SUMO_SIM_par_1 508 514 PF11976 0.341
LIG_SUMO_SIM_par_1 580 587 PF11976 0.440
LIG_SUMO_SIM_par_1 912 922 PF11976 0.391
LIG_SUMO_SIM_par_1 947 954 PF11976 0.369
LIG_SUMO_SIM_par_1 962 969 PF11976 0.431
LIG_TRAF2_1 1554 1557 PF00917 0.620
LIG_TYR_ITIM 1139 1144 PF00017 0.446
LIG_TYR_ITIM 1383 1388 PF00017 0.439
LIG_TYR_ITIM 1389 1394 PF00017 0.420
LIG_TYR_ITIM 1588 1593 PF00017 0.369
LIG_TYR_ITIM 933 938 PF00017 0.418
LIG_TYR_ITSM 1363 1370 PF00017 0.346
LIG_TYR_ITSM 460 467 PF00017 0.536
LIG_UBA3_1 1208 1216 PF00899 0.460
LIG_WRC_WIRS_1 1103 1108 PF05994 0.485
LIG_WRC_WIRS_1 1146 1151 PF05994 0.412
LIG_WRC_WIRS_1 1208 1213 PF05994 0.393
LIG_WRC_WIRS_1 1287 1292 PF05994 0.444
LIG_WRC_WIRS_1 1558 1563 PF05994 0.501
LIG_WRC_WIRS_1 1661 1666 PF05994 0.485
LIG_WRC_WIRS_1 1836 1841 PF05994 0.588
LIG_WRC_WIRS_1 365 370 PF05994 0.456
LIG_WRC_WIRS_1 747 752 PF05994 0.396
LIG_WRC_WIRS_1 760 765 PF05994 0.416
MOD_CDK_SPxK_1 1362 1368 PF00069 0.487
MOD_CDK_SPxK_1 266 272 PF00069 0.518
MOD_CDK_SPxxK_3 1189 1196 PF00069 0.511
MOD_CDK_SPxxK_3 1841 1848 PF00069 0.603
MOD_CK1_1 1286 1292 PF00069 0.427
MOD_CK1_1 1300 1306 PF00069 0.348
MOD_CK1_1 1521 1527 PF00069 0.628
MOD_CK1_1 1571 1577 PF00069 0.369
MOD_CK1_1 1643 1649 PF00069 0.369
MOD_CK1_1 1838 1844 PF00069 0.537
MOD_CK1_1 1846 1852 PF00069 0.574
MOD_CK1_1 1860 1866 PF00069 0.520
MOD_CK1_1 1887 1893 PF00069 0.711
MOD_CK1_1 192 198 PF00069 0.490
MOD_CK1_1 226 232 PF00069 0.564
MOD_CK1_1 357 363 PF00069 0.341
MOD_CK1_1 449 455 PF00069 0.387
MOD_CK1_1 519 525 PF00069 0.421
MOD_CK1_1 53 59 PF00069 0.527
MOD_CK1_1 581 587 PF00069 0.531
MOD_CK1_1 60 66 PF00069 0.469
MOD_CK1_1 608 614 PF00069 0.411
MOD_CK1_1 739 745 PF00069 0.429
MOD_CK1_1 749 755 PF00069 0.337
MOD_CK1_1 77 83 PF00069 0.303
MOD_CK1_1 793 799 PF00069 0.464
MOD_CK1_1 893 899 PF00069 0.496
MOD_CK1_1 978 984 PF00069 0.459
MOD_CK2_1 1132 1138 PF00069 0.379
MOD_CK2_1 124 130 PF00069 0.442
MOD_CK2_1 1551 1557 PF00069 0.537
MOD_CK2_1 163 169 PF00069 0.460
MOD_CK2_1 1747 1753 PF00069 0.369
MOD_CK2_1 1807 1813 PF00069 0.369
MOD_CK2_1 1824 1830 PF00069 0.506
MOD_CK2_1 1863 1869 PF00069 0.690
MOD_CMANNOS 115 118 PF00535 0.471
MOD_Cter_Amidation 526 529 PF01082 0.506
MOD_GlcNHglycan 1006 1009 PF01048 0.545
MOD_GlcNHglycan 1141 1144 PF01048 0.444
MOD_GlcNHglycan 13 16 PF01048 0.560
MOD_GlcNHglycan 145 148 PF01048 0.492
MOD_GlcNHglycan 1508 1511 PF01048 0.506
MOD_GlcNHglycan 155 158 PF01048 0.425
MOD_GlcNHglycan 1770 1773 PF01048 0.401
MOD_GlcNHglycan 1809 1812 PF01048 0.425
MOD_GlcNHglycan 1821 1824 PF01048 0.477
MOD_GlcNHglycan 1848 1851 PF01048 0.493
MOD_GlcNHglycan 250 253 PF01048 0.464
MOD_GlcNHglycan 318 322 PF01048 0.442
MOD_GlcNHglycan 419 422 PF01048 0.484
MOD_GlcNHglycan 448 451 PF01048 0.372
MOD_GlcNHglycan 453 456 PF01048 0.370
MOD_GlcNHglycan 524 527 PF01048 0.507
MOD_GlcNHglycan 586 589 PF01048 0.563
MOD_GlcNHglycan 619 622 PF01048 0.373
MOD_GlcNHglycan 623 626 PF01048 0.371
MOD_GlcNHglycan 685 688 PF01048 0.425
MOD_GlcNHglycan 724 727 PF01048 0.479
MOD_GlcNHglycan 738 741 PF01048 0.382
MOD_GlcNHglycan 770 774 PF01048 0.605
MOD_GlcNHglycan 795 798 PF01048 0.435
MOD_GlcNHglycan 818 821 PF01048 0.543
MOD_GlcNHglycan 836 839 PF01048 0.365
MOD_GlcNHglycan 844 848 PF01048 0.422
MOD_GlcNHglycan 880 883 PF01048 0.532
MOD_GlcNHglycan 977 980 PF01048 0.509
MOD_GSK3_1 1119 1126 PF00069 0.382
MOD_GSK3_1 1216 1223 PF00069 0.445
MOD_GSK3_1 1296 1303 PF00069 0.401
MOD_GSK3_1 1394 1401 PF00069 0.468
MOD_GSK3_1 1429 1436 PF00069 0.454
MOD_GSK3_1 1514 1521 PF00069 0.489
MOD_GSK3_1 1624 1631 PF00069 0.444
MOD_GSK3_1 1717 1724 PF00069 0.369
MOD_GSK3_1 1743 1750 PF00069 0.369
MOD_GSK3_1 1837 1844 PF00069 0.599
MOD_GSK3_1 1853 1860 PF00069 0.581
MOD_GSK3_1 1889 1896 PF00069 0.623
MOD_GSK3_1 222 229 PF00069 0.571
MOD_GSK3_1 242 249 PF00069 0.385
MOD_GSK3_1 319 326 PF00069 0.496
MOD_GSK3_1 330 337 PF00069 0.445
MOD_GSK3_1 356 363 PF00069 0.415
MOD_GSK3_1 417 424 PF00069 0.484
MOD_GSK3_1 437 444 PF00069 0.185
MOD_GSK3_1 451 458 PF00069 0.376
MOD_GSK3_1 471 478 PF00069 0.302
MOD_GSK3_1 506 513 PF00069 0.441
MOD_GSK3_1 518 525 PF00069 0.398
MOD_GSK3_1 53 60 PF00069 0.536
MOD_GSK3_1 570 577 PF00069 0.424
MOD_GSK3_1 586 593 PF00069 0.384
MOD_GSK3_1 617 624 PF00069 0.461
MOD_GSK3_1 637 644 PF00069 0.378
MOD_GSK3_1 653 660 PF00069 0.324
MOD_GSK3_1 66 73 PF00069 0.384
MOD_GSK3_1 74 81 PF00069 0.416
MOD_GSK3_1 749 756 PF00069 0.441
MOD_GSK3_1 810 817 PF00069 0.535
MOD_GSK3_1 900 907 PF00069 0.488
MOD_GSK3_1 911 918 PF00069 0.507
MOD_LATS_1 1002 1008 PF00433 0.563
MOD_N-GLC_1 109 114 PF02516 0.502
MOD_N-GLC_1 11 16 PF02516 0.390
MOD_N-GLC_1 1711 1716 PF02516 0.401
MOD_N-GLC_1 1875 1880 PF02516 0.761
MOD_N-GLC_1 1884 1889 PF02516 0.667
MOD_N-GLC_1 1893 1898 PF02516 0.583
MOD_N-GLC_1 326 331 PF02516 0.420
MOD_N-GLC_1 403 408 PF02516 0.529
MOD_N-GLC_1 441 446 PF02516 0.369
MOD_N-GLC_1 459 464 PF02516 0.438
MOD_N-GLC_1 506 511 PF02516 0.429
MOD_N-GLC_1 570 575 PF02516 0.420
MOD_N-GLC_1 66 71 PF02516 0.432
MOD_N-GLC_1 722 727 PF02516 0.494
MOD_N-GLC_1 753 758 PF02516 0.357
MOD_N-GLC_1 790 795 PF02516 0.447
MOD_N-GLC_2 181 183 PF02516 0.508
MOD_NEK2_1 109 114 PF00069 0.462
MOD_NEK2_1 1130 1135 PF00069 0.379
MOD_NEK2_1 1139 1144 PF00069 0.371
MOD_NEK2_1 1157 1162 PF00069 0.221
MOD_NEK2_1 1254 1259 PF00069 0.441
MOD_NEK2_1 1328 1333 PF00069 0.395
MOD_NEK2_1 1394 1399 PF00069 0.487
MOD_NEK2_1 1417 1422 PF00069 0.422
MOD_NEK2_1 1447 1452 PF00069 0.485
MOD_NEK2_1 1506 1511 PF00069 0.445
MOD_NEK2_1 1701 1706 PF00069 0.369
MOD_NEK2_1 1837 1842 PF00069 0.616
MOD_NEK2_1 1859 1864 PF00069 0.654
MOD_NEK2_1 1875 1880 PF00069 0.576
MOD_NEK2_1 189 194 PF00069 0.424
MOD_NEK2_1 221 226 PF00069 0.587
MOD_NEK2_1 317 322 PF00069 0.502
MOD_NEK2_1 354 359 PF00069 0.375
MOD_NEK2_1 364 369 PF00069 0.376
MOD_NEK2_1 388 393 PF00069 0.523
MOD_NEK2_1 417 422 PF00069 0.484
MOD_NEK2_1 441 446 PF00069 0.369
MOD_NEK2_1 510 515 PF00069 0.414
MOD_NEK2_1 578 583 PF00069 0.479
MOD_NEK2_1 590 595 PF00069 0.420
MOD_NEK2_1 641 646 PF00069 0.389
MOD_NEK2_1 682 687 PF00069 0.399
MOD_NEK2_1 70 75 PF00069 0.392
MOD_NEK2_1 731 736 PF00069 0.540
MOD_NEK2_1 790 795 PF00069 0.447
MOD_NEK2_1 816 821 PF00069 0.459
MOD_NEK2_1 852 857 PF00069 0.520
MOD_NEK2_1 904 909 PF00069 0.499
MOD_NEK2_2 1027 1032 PF00069 0.686
MOD_NEK2_2 1102 1107 PF00069 0.401
MOD_NEK2_2 288 293 PF00069 0.442
MOD_NEK2_2 35 40 PF00069 0.467
MOD_PIKK_1 1401 1407 PF00454 0.450
MOD_PIKK_1 1429 1435 PF00454 0.424
MOD_PIKK_1 1449 1455 PF00454 0.184
MOD_PIKK_1 1711 1717 PF00454 0.444
MOD_PIKK_1 204 210 PF00454 0.537
MOD_PIKK_1 343 349 PF00454 0.435
MOD_PIKK_1 466 472 PF00454 0.429
MOD_PIKK_1 800 806 PF00454 0.526
MOD_PIKK_1 810 816 PF00454 0.488
MOD_PK_1 475 481 PF00069 0.481
MOD_PKA_1 1216 1222 PF00069 0.468
MOD_PKA_1 1649 1655 PF00069 0.444
MOD_PKA_1 1807 1813 PF00069 0.369
MOD_PKA_2 1216 1222 PF00069 0.459
MOD_PKA_2 1315 1321 PF00069 0.384
MOD_PKA_2 1447 1453 PF00069 0.483
MOD_PKA_2 1807 1813 PF00069 0.384
MOD_PKA_2 254 260 PF00069 0.489
MOD_PKA_2 261 267 PF00069 0.527
MOD_PKA_2 330 336 PF00069 0.497
MOD_PKA_2 35 41 PF00069 0.420
MOD_PKA_2 360 366 PF00069 0.454
MOD_PKA_2 455 461 PF00069 0.558
MOD_PKA_2 492 498 PF00069 0.538
MOD_PKA_2 731 737 PF00069 0.523
MOD_PKA_2 814 820 PF00069 0.497
MOD_PKA_2 872 878 PF00069 0.574
MOD_PKA_2 909 915 PF00069 0.484
MOD_PKA_2 955 961 PF00069 0.536
MOD_PKB_1 1494 1502 PF00069 0.477
MOD_Plk_1 1137 1143 PF00069 0.372
MOD_Plk_1 1440 1446 PF00069 0.484
MOD_Plk_1 1711 1717 PF00069 0.429
MOD_Plk_1 28 34 PF00069 0.438
MOD_Plk_1 441 447 PF00069 0.384
MOD_Plk_1 485 491 PF00069 0.502
MOD_Plk_1 506 512 PF00069 0.426
MOD_Plk_1 546 552 PF00069 0.457
MOD_Plk_1 579 585 PF00069 0.450
MOD_Plk_1 605 611 PF00069 0.395
MOD_Plk_1 66 72 PF00069 0.432
MOD_Plk_1 670 676 PF00069 0.490
MOD_Plk_1 753 759 PF00069 0.383
MOD_Plk_1 790 796 PF00069 0.448
MOD_Plk_1 900 906 PF00069 0.484
MOD_Plk_2-3 574 580 PF00069 0.485
MOD_Plk_4 1092 1098 PF00069 0.436
MOD_Plk_4 1108 1114 PF00069 0.313
MOD_Plk_4 1216 1222 PF00069 0.468
MOD_Plk_4 1238 1244 PF00069 0.412
MOD_Plk_4 1254 1260 PF00069 0.275
MOD_Plk_4 1263 1269 PF00069 0.335
MOD_Plk_4 1297 1303 PF00069 0.466
MOD_Plk_4 1328 1334 PF00069 0.412
MOD_Plk_4 1548 1554 PF00069 0.562
MOD_Plk_4 1628 1634 PF00069 0.432
MOD_Plk_4 1643 1649 PF00069 0.298
MOD_Plk_4 1717 1723 PF00069 0.369
MOD_Plk_4 1747 1753 PF00069 0.369
MOD_Plk_4 192 198 PF00069 0.402
MOD_Plk_4 261 267 PF00069 0.479
MOD_Plk_4 319 325 PF00069 0.498
MOD_Plk_4 330 336 PF00069 0.459
MOD_Plk_4 35 41 PF00069 0.419
MOD_Plk_4 360 366 PF00069 0.440
MOD_Plk_4 388 394 PF00069 0.371
MOD_Plk_4 441 447 PF00069 0.364
MOD_Plk_4 519 525 PF00069 0.476
MOD_Plk_4 560 566 PF00069 0.366
MOD_Plk_4 586 592 PF00069 0.498
MOD_Plk_4 608 614 PF00069 0.405
MOD_Plk_4 670 676 PF00069 0.490
MOD_Plk_4 689 695 PF00069 0.228
MOD_Plk_4 74 80 PF00069 0.393
MOD_Plk_4 746 752 PF00069 0.417
MOD_Plk_4 753 759 PF00069 0.379
MOD_Plk_4 790 796 PF00069 0.522
MOD_Plk_4 88 94 PF00069 0.433
MOD_Plk_4 893 899 PF00069 0.439
MOD_Plk_4 900 906 PF00069 0.413
MOD_Plk_4 919 925 PF00069 0.351
MOD_Plk_4 927 933 PF00069 0.402
MOD_Plk_4 946 952 PF00069 0.362
MOD_Plk_4 955 961 PF00069 0.496
MOD_ProDKin_1 1123 1129 PF00069 0.360
MOD_ProDKin_1 1189 1195 PF00069 0.513
MOD_ProDKin_1 131 137 PF00069 0.569
MOD_ProDKin_1 1362 1368 PF00069 0.352
MOD_ProDKin_1 1541 1547 PF00069 0.573
MOD_ProDKin_1 1594 1600 PF00069 0.444
MOD_ProDKin_1 1721 1727 PF00069 0.369
MOD_ProDKin_1 1841 1847 PF00069 0.561
MOD_ProDKin_1 1860 1866 PF00069 0.405
MOD_ProDKin_1 1870 1876 PF00069 0.737
MOD_ProDKin_1 266 272 PF00069 0.518
MOD_ProDKin_1 380 386 PF00069 0.465
MOD_ProDKin_1 403 409 PF00069 0.523
MOD_ProDKin_1 890 896 PF00069 0.516
MOD_SUMO_for_1 1461 1464 PF00179 0.436
MOD_SUMO_for_1 1683 1686 PF00179 0.369
MOD_SUMO_for_1 841 844 PF00179 0.548
MOD_SUMO_for_1 966 969 PF00179 0.476
MOD_SUMO_rev_2 412 418 PF00179 0.506
TRG_DiLeu_BaEn_4 605 611 PF01217 0.461
TRG_DiLeu_BaLyEn_6 472 477 PF01217 0.320
TRG_DiLeu_BaLyEn_6 627 632 PF01217 0.465
TRG_DiLeu_BaLyEn_6 693 698 PF01217 0.449
TRG_ENDOCYTIC_2 1141 1144 PF00928 0.362
TRG_ENDOCYTIC_2 1146 1149 PF00928 0.325
TRG_ENDOCYTIC_2 1240 1243 PF00928 0.429
TRG_ENDOCYTIC_2 1274 1277 PF00928 0.447
TRG_ENDOCYTIC_2 1367 1370 PF00928 0.346
TRG_ENDOCYTIC_2 1385 1388 PF00928 0.344
TRG_ENDOCYTIC_2 1391 1394 PF00928 0.337
TRG_ENDOCYTIC_2 1572 1575 PF00928 0.369
TRG_ENDOCYTIC_2 1590 1593 PF00928 0.369
TRG_ENDOCYTIC_2 1770 1773 PF00928 0.369
TRG_ENDOCYTIC_2 244 247 PF00928 0.479
TRG_ENDOCYTIC_2 386 389 PF00928 0.411
TRG_ENDOCYTIC_2 40 43 PF00928 0.441
TRG_ENDOCYTIC_2 464 467 PF00928 0.530
TRG_ENDOCYTIC_2 484 487 PF00928 0.196
TRG_ENDOCYTIC_2 505 508 PF00928 0.413
TRG_ENDOCYTIC_2 550 553 PF00928 0.455
TRG_ENDOCYTIC_2 721 724 PF00928 0.510
TRG_ENDOCYTIC_2 935 938 PF00928 0.418
TRG_ER_diArg_1 1041 1044 PF00400 0.437
TRG_ER_diArg_1 118 120 PF00400 0.512
TRG_ER_diArg_1 1225 1228 PF00400 0.375
TRG_ER_diArg_1 1313 1316 PF00400 0.403
TRG_ER_diArg_1 1454 1457 PF00400 0.421
TRG_ER_diArg_1 1483 1486 PF00400 0.424
TRG_ER_diArg_1 236 239 PF00400 0.467
TRG_ER_diArg_1 436 439 PF00400 0.489
TRG_ER_diArg_1 731 733 PF00400 0.450
TRG_ER_diArg_1 93 95 PF00400 0.559
TRG_ER_diLys_1 1897 1900 PF00400 0.564
TRG_NES_CRM1_1 1475 1490 PF08389 0.537
TRG_NES_CRM1_1 1599 1613 PF08389 0.444
TRG_NES_CRM1_1 486 499 PF08389 0.481
TRG_NLS_Bipartite_1 1198 1219 PF00514 0.466
TRG_Pf-PMV_PEXEL_1 556 560 PF00026 0.376
TRG_Pf-PMV_PEXEL_1 630 634 PF00026 0.468
TRG_Pf-PMV_PEXEL_1 696 700 PF00026 0.491
TRG_Pf-PMV_PEXEL_1 961 965 PF00026 0.569

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1HYY7 Leptomonas seymouri 68% 100%
A0A1X0P1C9 Trypanosomatidae 36% 100%
A0A422P0W2 Trypanosoma rangeli 31% 100%
A4HIN9 Leishmania braziliensis 83% 100%
A4I5Y6 Leishmania infantum 100% 100%
E9B179 Leishmania mexicana (strain MHOM/GT/2001/U1103) 92% 100%
Q4Q6Y5 Leishmania major 94% 100%
V5BSF9 Trypanosoma cruzi 38% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2024 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS