Lsm5p, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Lsm5p, putative

Gene product:

Lsm5p, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X3R7_LEIDO

TriTrypDb:

LdBPK_303040.1 , LdCL_300036000 , LDHU3_30.4040

Length:

128

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X3R7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X3R7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	63	65	PF00675	0.361
CLV_PCSK_KEX2_1	15	17	PF00082	0.577
CLV_PCSK_KEX2_1	61	63	PF00082	0.345
CLV_PCSK_PC1ET2_1	15	17	PF00082	0.562
CLV_PCSK_PC1ET2_1	61	63	PF00082	0.342
CLV_PCSK_PC7_1	58	64	PF00082	0.361
CLV_PCSK_SKI1_1	58	62	PF00082	0.356
DEG_Nend_Nbox_1	1	3	PF02207	0.553
DEG_SCF_TRCP1_1	94	99	PF00400	0.681
DOC_MAPK_gen_1	15	22	PF00069	0.429
DOC_MAPK_RevD_3	49	64	PF00069	0.574
DOC_USP7_MATH_1	112	116	PF00917	0.651
DOC_USP7_MATH_1	123	127	PF00917	0.569
DOC_USP7_MATH_1	5	9	PF00917	0.667
LIG_14-3-3_CanoR_1	25	31	PF00244	0.584
LIG_14-3-3_CanoR_1	39	44	PF00244	0.561
LIG_14-3-3_CanoR_1	84	89	PF00244	0.527
LIG_FHA_2	27	33	PF00498	0.590
LIG_FHA_2	50	56	PF00498	0.535
LIG_FHA_2	70	76	PF00498	0.445
LIG_LIR_Gen_1	75	83	PF02991	0.557
LIG_LIR_Nem_3	75	80	PF02991	0.557
LIG_SH2_CRK	77	81	PF00017	0.541
LIG_SH2_STAP1	77	81	PF00017	0.598
LIG_SH2_STAT5	21	24	PF00017	0.635
LIG_SUMO_SIM_par_1	39	45	PF11976	0.635
LIG_SUMO_SIM_par_1	7	14	PF11976	0.526
MOD_CK1_1	42	48	PF00069	0.569
MOD_CK1_1	87	93	PF00069	0.531
MOD_CK1_1	95	101	PF00069	0.549
MOD_CK2_1	49	55	PF00069	0.531
MOD_CK2_1	69	75	PF00069	0.445
MOD_GlcNHglycan	7	10	PF01048	0.737
MOD_GlcNHglycan	94	97	PF01048	0.558
MOD_GSK3_1	1	8	PF00069	0.679
MOD_GSK3_1	83	90	PF00069	0.546
MOD_GSK3_1	92	99	PF00069	0.491
MOD_N-GLC_1	112	117	PF02516	0.713
MOD_NEK2_1	1	6	PF00069	0.742
MOD_PK_1	84	90	PF00069	0.527
MOD_PKA_2	83	89	PF00069	0.661
MOD_Plk_1	112	118	PF00069	0.643
MOD_Plk_1	31	37	PF00069	0.568
MOD_Plk_1	99	105	PF00069	0.597
MOD_Plk_4	31	37	PF00069	0.587
MOD_Plk_4	84	90	PF00069	0.548
MOD_Plk_4	99	105	PF00069	0.574
TRG_DiLeu_BaEn_1	14	19	PF01217	0.557
TRG_ENDOCYTIC_2	77	80	PF00928	0.542
TRG_ER_diArg_1	56	59	PF00400	0.550
TRG_ER_diArg_1	62	64	PF00400	0.533
TRG_NLS_MonoCore_2	60	65	PF00514	0.556
TRG_NLS_MonoExtN_4	58	65	PF00514	0.543

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P6D6	Leptomonas seymouri	83%	96%
A0A0S4IPA9	Bodo saltans	39%	100%
A0A1X0P2Y8	Trypanosomatidae	54%	100%
A0A422P0R9	Trypanosoma rangeli	55%	100%
A4HIN4	Leishmania braziliensis	84%	100%
A4I5Y1	Leishmania infantum	99%	100%
C9ZRA7	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	50%	100%
E9B174	Leishmania mexicana (strain MHOM/GT/2001/U1103)	92%	100%
Q4Q6Z0	Leishmania major	94%	100%
V5BX96	Trypanosoma cruzi	56%	100%