Hypothetical_protein_conserved

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X3R6_LEIDO

TriTrypDb:

LdBPK_303060.1 , LdCL_300036200 , LDHU3_30.4070

Length:

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X3R6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X3R6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	36	38	PF00675	0.497
CLV_PCSK_SKI1_1	82	86	PF00082	0.606
DEG_APCC_DBOX_1	36	44	PF00400	0.499
DEG_Nend_UBRbox_2	1	3	PF02207	0.560
DOC_USP7_MATH_1	47	51	PF00917	0.542
DOC_WW_Pin1_4	52	57	PF00397	0.501
LIG_14-3-3_CanoR_1	37	41	PF00244	0.502
LIG_14-3-3_CanoR_1	46	52	PF00244	0.450
LIG_LIR_Apic_2	59	63	PF02991	0.593
LIG_LIR_Gen_1	4	14	PF02991	0.493
LIG_LIR_Nem_3	4	10	PF02991	0.513
LIG_NRBOX	39	45	PF00104	0.506
LIG_SH2_CRK	60	64	PF00017	0.444
LIG_SH3_3	22	28	PF00018	0.464
LIG_SH3_3	50	56	PF00018	0.582
LIG_SH3_3	66	72	PF00018	0.503
LIG_SH3_3	74	80	PF00018	0.543
LIG_SH3_5	56	60	PF00018	0.490
MOD_CK1_1	18	24	PF00069	0.561
MOD_NEK2_1	1	6	PF00069	0.565
MOD_NEK2_1	10	15	PF00069	0.471
MOD_NEK2_2	47	52	PF00069	0.547
MOD_PKA_2	36	42	PF00069	0.498
MOD_Plk_4	18	24	PF00069	0.536
MOD_ProDKin_1	52	58	PF00069	0.497
MOD_SUMO_rev_2	13	21	PF00179	0.453
TRG_ENDOCYTIC_2	33	36	PF00928	0.470

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HIN6	Leishmania braziliensis	96%	100%
A4I5Y3	Leishmania infantum	100%	100%
E9B176	Leishmania mexicana (strain MHOM/GT/2001/U1103)	95%	100%
Q4Q6Y8	Leishmania major	97%	100%