LeishMANIAdb
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Triose-phosphate Transporter family, putative

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Triose-phosphate Transporter family, putative
Gene product:
Triose-phosphate Transporter family, putative
Species:
Leishmania donovani
UniProt:
A0A3S7X3R1_LEIDO
TriTrypDb:
LdBPK_302680.1 , LdCL_300032400 , LDHU3_30.3580
Length:
325

Annotations

LeishMANIAdb annotations

Related to plant and animal nucleoside-sugar transporters, often localized to the Golgi apparatus.. An expanded family in kinetoplastids, possibly to cover the need for expanded proteoglycan biosynthesis. Localization: Golgi (by homology)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 19
NetGPI no yes: 0, no: 19
Cellular components
TermNameLevelCount
GO:0005794 Golgi apparatus 5 2
GO:0016020 membrane 2 20
GO:0043226 organelle 2 2
GO:0043227 membrane-bounded organelle 3 2
GO:0043229 intracellular organelle 3 2
GO:0043231 intracellular membrane-bounded organelle 4 2
GO:0110165 cellular anatomical entity 1 20
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Expansion

Sequence features

A0A3S7X3R1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X3R1

Function

Could not find GO biological_process term for this entry.
Molecular functions
TermNameLevelCount
GO:0005215 transporter activity 1 2
GO:0005338 nucleotide-sugar transmembrane transporter activity 4 2
GO:0015291 secondary active transmembrane transporter activity 4 2
GO:0015297 antiporter activity 5 2
GO:0015932 nucleobase-containing compound transmembrane transporter activity 3 2
GO:0022804 active transmembrane transporter activity 3 2
GO:0022857 transmembrane transporter activity 2 2
GO:1901505 carbohydrate derivative transmembrane transporter activity 3 2
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 70 72 PF00675 0.317
CLV_PCSK_KEX2_1 119 121 PF00082 0.246
CLV_PCSK_KEX2_1 25 27 PF00082 0.477
CLV_PCSK_KEX2_1 70 72 PF00082 0.274
CLV_PCSK_PC1ET2_1 119 121 PF00082 0.277
CLV_PCSK_PC1ET2_1 25 27 PF00082 0.477
CLV_PCSK_SKI1_1 26 30 PF00082 0.473
CLV_PCSK_SKI1_1 60 64 PF00082 0.283
CLV_PCSK_SKI1_1 70 74 PF00082 0.268
DEG_APCC_DBOX_1 119 127 PF00400 0.483
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P8N6 Leptomonas seymouri 39% 100%
A0A0N1PAW1 Leptomonas seymouri 70% 100%
A0A0S4IKX4 Bodo saltans 37% 100%
A0A0S4JRZ1 Bodo saltans 36% 100%
A0A1X0P276 Trypanosomatidae 65% 100%
A0A1X0P5Z4 Trypanosomatidae 41% 100%
A0A3R7NGZ9 Trypanosoma rangeli 63% 100%
A0A3S7WVL9 Leishmania donovani 38% 100%
A0A422NUS0 Trypanosoma rangeli 40% 100%
A4HAA0 Leishmania braziliensis 34% 100%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS