Replication_factor_C_subunit_2_putative/GeneDB:Lm jF.30.2630

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

replication factor C, subunit 2, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X3R0_LEIDO

TriTrypDb:

LdBPK_302620.1 , LdCL_300031800 , LDHU3_30.3520

Length:

354

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 18

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0005654	nucleoplasm	2	1
GO:0005663	DNA replication factor C complex	2	1
GO:0032991	protein-containing complex	1	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3S7X3R0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X3R0

Function

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	12
GO:0006259	DNA metabolic process	4	12
GO:0006260	DNA replication	5	12
GO:0006725	cellular aromatic compound metabolic process	3	12
GO:0006807	nitrogen compound metabolic process	2	12
GO:0008152	metabolic process	1	12
GO:0009987	cellular process	1	12
GO:0034641	cellular nitrogen compound metabolic process	3	12
GO:0043170	macromolecule metabolic process	3	12
GO:0044237	cellular metabolic process	2	12
GO:0044238	primary metabolic process	2	12
GO:0044260	obsolete cellular macromolecule metabolic process	3	12
GO:0046483	heterocycle metabolic process	3	12
GO:0071704	organic substance metabolic process	2	12
GO:0090304	nucleic acid metabolic process	4	12
GO:1901360	organic cyclic compound metabolic process	3	12
GO:0006261	DNA-templated DNA replication	6	1
GO:0006281	DNA repair	5	1
GO:0006950	response to stress	2	1
GO:0006974	DNA damage response	4	1
GO:0033554	cellular response to stress	3	1
GO:0050896	response to stimulus	1	1
GO:0051716	cellular response to stimulus	2	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	12
GO:0003676	nucleic acid binding	3	12
GO:0003677	DNA binding	4	12
GO:0003824	catalytic activity	1	12
GO:0005488	binding	1	12
GO:0005524	ATP binding	5	12
GO:0016462	pyrophosphatase activity	5	12
GO:0016787	hydrolase activity	2	12
GO:0016817	hydrolase activity, acting on acid anhydrides	3	12
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	12
GO:0016887	ATP hydrolysis activity	7	12
GO:0017076	purine nucleotide binding	4	12
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	12
GO:0030554	adenyl nucleotide binding	5	12
GO:0032553	ribonucleotide binding	3	12
GO:0032555	purine ribonucleotide binding	4	12
GO:0032559	adenyl ribonucleotide binding	5	12
GO:0035639	purine ribonucleoside triphosphate binding	4	12
GO:0036094	small molecule binding	2	12
GO:0043167	ion binding	2	12
GO:0043168	anion binding	3	12
GO:0097159	organic cyclic compound binding	2	12
GO:0097367	carbohydrate derivative binding	2	12
GO:1901265	nucleoside phosphate binding	3	12
GO:1901363	heterocyclic compound binding	2	12

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	127	131	PF00656	0.423
CLV_C14_Caspase3-7	145	149	PF00656	0.143
CLV_NRD_NRD_1	159	161	PF00675	0.253
CLV_NRD_NRD_1	288	290	PF00675	0.329
CLV_NRD_NRD_1	332	334	PF00675	0.313
CLV_PCSK_KEX2_1	10	12	PF00082	0.629
CLV_PCSK_KEX2_1	159	161	PF00082	0.253
CLV_PCSK_KEX2_1	288	290	PF00082	0.369
CLV_PCSK_KEX2_1	332	334	PF00082	0.253
CLV_PCSK_PC1ET2_1	10	12	PF00082	0.661
CLV_PCSK_SKI1_1	10	14	PF00082	0.716
CLV_PCSK_SKI1_1	188	192	PF00082	0.253
CLV_PCSK_SKI1_1	199	203	PF00082	0.319
CLV_PCSK_SKI1_1	322	326	PF00082	0.325
DEG_SPOP_SBC_1	118	122	PF00917	0.281
DOC_ANK_TNKS_1	288	295	PF00023	0.329
DOC_ANK_TNKS_1	331	338	PF00023	0.396
DOC_MAPK_gen_1	320	327	PF00069	0.347
DOC_MAPK_MEF2A_6	320	327	PF00069	0.253
DOC_MAPK_NFAT4_5	320	328	PF00069	0.313
DOC_PP4_FxxP_1	64	67	PF00568	0.253
DOC_SPAK_OSR1_1	170	174	PF12202	0.253
DOC_USP7_MATH_1	118	122	PF00917	0.414
DOC_USP7_MATH_1	184	188	PF00917	0.253
DOC_USP7_MATH_1	314	318	PF00917	0.268
DOC_USP7_MATH_1	350	354	PF00917	0.453
DOC_USP7_UBL2_3	191	195	PF12436	0.253
DOC_USP7_UBL2_3	322	326	PF12436	0.329
DOC_WW_Pin1_4	215	220	PF00397	0.497
LIG_14-3-3_CanoR_1	32	37	PF00244	0.381
LIG_Actin_WH2_2	218	236	PF00022	0.335
LIG_BIR_II_1	1	5	PF00653	0.631
LIG_BRCT_BRCA1_1	272	276	PF00533	0.360
LIG_Clathr_ClatBox_1	141	145	PF01394	0.268
LIG_eIF4E_1	192	198	PF01652	0.344
LIG_EVH1_1	134	138	PF00568	0.313
LIG_FHA_1	71	77	PF00498	0.289
LIG_FHA_2	125	131	PF00498	0.329
LIG_FHA_2	33	39	PF00498	0.459
LIG_LIR_Gen_1	163	173	PF02991	0.258
LIG_LIR_Gen_1	200	210	PF02991	0.370
LIG_LIR_Gen_1	254	264	PF02991	0.352
LIG_LIR_Gen_1	339	347	PF02991	0.268
LIG_LIR_Nem_3	163	168	PF02991	0.258
LIG_LIR_Nem_3	169	174	PF02991	0.293
LIG_LIR_Nem_3	200	206	PF02991	0.376
LIG_LIR_Nem_3	254	259	PF02991	0.366
LIG_LIR_Nem_3	339	344	PF02991	0.268
LIG_Pex14_1	27	31	PF04695	0.347
LIG_SH2_STAT3	208	211	PF00017	0.462
LIG_SH2_STAT5	177	180	PF00017	0.293
LIG_SH2_STAT5	208	211	PF00017	0.462
LIG_SH2_STAT5	271	274	PF00017	0.286
LIG_SH2_STAT5	307	310	PF00017	0.288
LIG_SH2_STAT5	341	344	PF00017	0.347
LIG_SH2_STAT5	88	91	PF00017	0.309
LIG_SH3_1	132	138	PF00018	0.347
LIG_SH3_2	135	140	PF14604	0.313
LIG_SH3_3	132	138	PF00018	0.320
LIG_SH3_4	195	202	PF00018	0.347
LIG_Sin3_3	147	154	PF02671	0.253
LIG_SUMO_SIM_par_1	140	146	PF11976	0.268
LIG_SUMO_SIM_par_1	343	349	PF11976	0.313
LIG_UBA3_1	237	245	PF00899	0.365
MOD_CK1_1	121	127	PF00069	0.413
MOD_CK1_1	166	172	PF00069	0.280
MOD_CK1_1	2	8	PF00069	0.617
MOD_CK1_1	218	224	PF00069	0.348
MOD_CK2_1	32	38	PF00069	0.432
MOD_GlcNHglycan	121	124	PF01048	0.382
MOD_GlcNHglycan	199	202	PF01048	0.465
MOD_GlcNHglycan	228	231	PF01048	0.346
MOD_GlcNHglycan	241	244	PF01048	0.325
MOD_GlcNHglycan	259	262	PF01048	0.348
MOD_GlcNHglycan	272	275	PF01048	0.295
MOD_GlcNHglycan	309	312	PF01048	0.325
MOD_GlcNHglycan	316	319	PF01048	0.297
MOD_GlcNHglycan	348	351	PF01048	0.333
MOD_GSK3_1	11	18	PF00069	0.732
MOD_GSK3_1	117	124	PF00069	0.334
MOD_GSK3_1	255	262	PF00069	0.445
MOD_GSK3_1	270	277	PF00069	0.269
MOD_GSK3_1	346	353	PF00069	0.383
MOD_GSK3_1	67	74	PF00069	0.304
MOD_N-GLC_1	96	101	PF02516	0.256
MOD_NEK2_1	1	6	PF00069	0.716
MOD_NEK2_1	197	202	PF00069	0.488
MOD_PIKK_1	124	130	PF00454	0.329
MOD_PIKK_1	2	8	PF00454	0.709
MOD_PK_1	72	78	PF00069	0.358
MOD_Plk_1	166	172	PF00069	0.255
MOD_Plk_4	72	78	PF00069	0.358
MOD_ProDKin_1	215	221	PF00069	0.490
MOD_SUMO_for_1	12	15	PF00179	0.713
MOD_SUMO_rev_2	124	133	PF00179	0.388
TRG_DiLeu_BaEn_1	146	151	PF01217	0.253
TRG_ENDOCYTIC_2	203	206	PF00928	0.341
TRG_ENDOCYTIC_2	341	344	PF00928	0.347
TRG_ER_diArg_1	158	160	PF00400	0.253
TRG_ER_diArg_1	288	290	PF00400	0.329
TRG_ER_diArg_1	31	34	PF00400	0.502
TRG_ER_diArg_1	332	334	PF00400	0.358
TRG_ER_diArg_1	89	92	PF00400	0.397
TRG_NLS_MonoExtC_3	9	15	PF00514	0.589
TRG_NLS_MonoExtN_4	7	14	PF00514	0.605
TRG_Pf-PMV_PEXEL_1	288	293	PF00026	0.390
TRG_Pf-PMV_PEXEL_1	332	336	PF00026	0.313
TRG_Pf-PMV_PEXEL_1	34	38	PF00026	0.472

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P564	Leptomonas seymouri	43%	97%
A0A0N0P777	Leptomonas seymouri	37%	98%
A0A0N1IAI3	Leptomonas seymouri	31%	100%
A0A0N1PCT2	Leptomonas seymouri	85%	100%
A0A0S4IM83	Bodo saltans	36%	100%
A0A0S4JFI8	Bodo saltans	66%	100%
A0A0S4JGB9	Bodo saltans	37%	94%
A0A1X0NN25	Trypanosomatidae	29%	100%
A0A1X0P333	Trypanosomatidae	70%	100%
A0A1X0P3R4	Trypanosomatidae	38%	100%
A0A1X0P5L7	Trypanosomatidae	41%	99%
A0A3Q8IDA5	Leishmania donovani	36%	100%
A0A3Q8IVD9	Leishmania donovani	39%	100%
A0A3R7KCC2	Trypanosoma rangeli	39%	100%
A0A3R7KEM0	Trypanosoma rangeli	68%	100%
A0A3R7KKZ5	Trypanosoma rangeli	29%	100%
A0A3R7LYZ3	Trypanosoma rangeli	38%	100%
A0A3S7XCG1	Leishmania donovani	33%	100%
A0B6D7	Methanothrix thermoacetophila (strain DSM 6194 / JCM 14653 / NBRC 101360 / PT)	30%	76%
A1RSA2	Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)	40%	100%
A1RSA3	Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)	27%	84%
A1RV38	Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3)	42%	100%
A1RWU7	Thermofilum pendens (strain DSM 2475 / Hrk 5)	41%	100%
A2BL93	Hyperthermus butylicus (strain DSM 5456 / JCM 9403 / PLM1-5)	29%	73%
A2SQT3	Methanocorpusculum labreanum (strain ATCC 43576 / DSM 4855 / Z)	38%	100%
A3CUX9	Methanoculleus marisnigri (strain ATCC 35101 / DSM 1498 / JR1)	38%	100%
A3DNV8	Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1)	27%	84%
A3DNV9	Staphylothermus marinus (strain ATCC 43588 / DSM 3639 / JCM 9404 / F1)	39%	100%
A3MS27	Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1)	26%	84%
A3MS28	Pyrobaculum calidifontis (strain DSM 21063 / JCM 11548 / VA1)	39%	100%
A4FZ74	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	39%	100%
A4FZL6	Methanococcus maripaludis (strain C5 / ATCC BAA-1333)	28%	73%
A4HFI1	Leishmania braziliensis	36%	100%
A4HIJ5	Leishmania braziliensis	96%	100%
A4HMZ2	Leishmania braziliensis	39%	100%
A4HQJ4	Leishmania braziliensis	29%	100%
A4I5T9	Leishmania infantum	100%	100%
A4IBL6	Leishmania infantum	39%	100%
A4WGV2	Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321 / PZ6)	42%	100%
A4WGV3	Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321 / PZ6)	27%	84%
A4WLY0	Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321 / PZ6)	46%	100%
A5UMF3	Methanobrevibacter smithii (strain ATCC 35061 / DSM 861 / OCM 144 / PS)	37%	100%
A6US36	Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)	35%	100%
A6VIW1	Methanococcus maripaludis (strain C7 / ATCC BAA-1331)	27%	73%
A6VJ61	Methanococcus maripaludis (strain C7 / ATCC BAA-1331)	39%	100%
A8AC24	Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125)	28%	74%
A9A6K6	Methanococcus maripaludis (strain C6 / ATCC BAA-1332)	40%	100%
A9A6N2	Methanococcus maripaludis (strain C6 / ATCC BAA-1332)	27%	73%
B0R601	Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)	28%	75%
B0R7H7	Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1)	36%	100%
B1YC69	Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / NBRC 100436 / V24Sta)	27%	84%
B9LPV1	Halorubrum lacusprofundi (strain ATCC 49239 / DSM 5036 / JCM 8891 / ACAM 34)	26%	71%
C9ZR59	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	69%	100%
C9ZZ23	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	99%
D0A3P3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	30%	100%
D0A8F2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
E9AD32	Leishmania major	36%	100%
E9AFE9	Leishmania major	39%	100%
E9AHC5	Leishmania infantum	36%	100%
E9AI03	Leishmania infantum	33%	100%
E9AUA7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	28%	100%
E9AYV6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	36%	100%
E9B134	Leishmania mexicana (strain MHOM/GT/2001/U1103)	99%	100%
E9B6K4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	39%	100%
O14003	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	35%	100%
O26342	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)	28%	74%
O26343	Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H)	34%	100%
O28219	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	41%	100%
O29072	Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16)	30%	74%
O74111	Blastobotrys adeninivorans	39%	100%
O94449	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	36%	100%
O94697	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	27%	99%
P0C7N7	Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173)	39%	86%
P34429	Caenorhabditis elegans	39%	96%
P35249	Homo sapiens	46%	98%
P35250	Homo sapiens	32%	100%
P38251	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	28%	100%
P38629	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	39%	100%
P40339	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	36%	100%
P40348	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	43%	100%
P40937	Homo sapiens	36%	100%
P40938	Homo sapiens	31%	99%
P53016	Caenorhabditis elegans	39%	100%
P53033	Gallus gallus	34%	99%
P53034	Drosophila melanogaster	31%	100%
P57553	Buchnera aphidicola subsp. Acyrthosiphon pisum (strain APS)	21%	98%
P60373	Nanoarchaeum equitans (strain Kin4-M)	30%	82%
P60374	Nanoarchaeum equitans (strain Kin4-M)	39%	100%
Q05B83	Bos taurus	33%	100%
Q09843	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	44%	100%
Q0W037	Methanocella arvoryzae (strain DSM 22066 / NBRC 105507 / MRE50)	36%	100%
Q12TX1	Methanococcoides burtonii (strain DSM 6242 / NBRC 107633 / OCM 468 / ACE-M)	29%	71%
Q18GQ9	Haloquadratum walsbyi (strain DSM 16790 / HBSQ001)	28%	69%
Q2FQR4	Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)	33%	73%
Q2FQT9	Methanospirillum hungatei JF-1 (strain ATCC 27890 / DSM 864 / NBRC 100397 / JF-1)	37%	100%
Q2NH89	Methanosphaera stadtmanae (strain ATCC 43021 / DSM 3091 / JCM 11832 / MCB-3)	33%	100%
Q2TBV1	Bos taurus	31%	99%
Q3ITJ2	Natronomonas pharaonis (strain ATCC 35678 / DSM 2160 / CIP 103997 / JCM 8858 / NBRC 14720 / NCIMB 2260 / Gabara)	36%	100%
Q46C63	Methanosarcina barkeri (strain Fusaro / DSM 804)	38%	100%
Q4JAB0	Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)	38%	100%
Q4Q084	Leishmania major	28%	100%
Q4Q732	Leishmania major	99%	100%
Q54BN3	Dictyostelium discoideum	31%	100%
Q54E21	Dictyostelium discoideum	32%	100%
Q54MD4	Dictyostelium discoideum	44%	100%
Q54ST4	Dictyostelium discoideum	35%	100%
Q58294	Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440)	25%	69%
Q5UP47	Acanthamoeba polyphaga mimivirus	37%	100%
Q5UQ72	Acanthamoeba polyphaga mimivirus	34%	98%
Q5UZE5	Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)	37%	100%
Q641W4	Rattus norvegicus	33%	100%
Q6L1I0	Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)	36%	100%
Q6M044	Methanococcus maripaludis (strain S2 / LL)	39%	100%
Q6M0E9	Methanococcus maripaludis (strain S2 / LL)	28%	73%
Q6YZ54	Oryza sativa subsp. japonica	37%	98%
Q7XRX1	Oryza sativa subsp. japonica	37%	100%
Q852K3	Oryza sativa subsp. japonica	25%	100%
Q8PVY4	Methanosarcina mazei (strain ATCC BAA-159 / DSM 3647 / Goe1 / Go1 / JCM 11833 / OCM 88)	38%	100%
Q8R323	Mus musculus	31%	99%
Q8SQM0	Encephalitozoon cuniculi (strain GB-M1)	34%	100%
Q8TSX5	Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A)	38%	100%
Q8TZC5	Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)	32%	69%
Q8VXX4	Arabidopsis thaliana	27%	100%
Q8X082	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	29%	100%
Q8ZYK3	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	27%	84%
Q8ZYK4	Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2)	41%	100%
Q93ZX1	Arabidopsis thaliana	49%	100%
Q975D3	Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)	37%	100%
Q977Z9	Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)	34%	100%
Q99J62	Mus musculus	46%	97%
Q9CAQ8	Arabidopsis thaliana	37%	96%
Q9D0F6	Mus musculus	35%	100%
Q9FXM3	Oryza sativa subsp. japonica	48%	100%
Q9HI47	Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)	34%	100%
Q9HN27	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	36%	100%
Q9HPI4	Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)	28%	75%
Q9UXF5	Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)	39%	100%
Q9WUK4	Mus musculus	33%	100%
Q9YBS5	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	28%	74%
Q9YBS7	Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)	40%	100%
V5BM57	Trypanosoma cruzi	29%	100%
V5BMW7	Trypanosoma cruzi	69%	100%
V5C2V9	Trypanosoma cruzi	40%	100%