LeishMANIAdb
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DNAJ domain protein, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
DNAJ domain protein, putative
Gene product:
DNAJ domain protein, putative
Species:
Leishmania donovani
UniProt:
A0A3S7X3L8_LEIDO
TriTrypDb:
LdBPK_301790.1 * , LdCL_300023200 , LDHU3_30.2500
Length:
740

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 5
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 4
NetGPI no yes: 0, no: 4
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X3L8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X3L8

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 224 228 PF00656 0.601
CLV_C14_Caspase3-7 394 398 PF00656 0.617
CLV_C14_Caspase3-7 77 81 PF00656 0.385
CLV_NRD_NRD_1 266 268 PF00675 0.530
CLV_NRD_NRD_1 47 49 PF00675 0.407
CLV_NRD_NRD_1 616 618 PF00675 0.646
CLV_NRD_NRD_1 625 627 PF00675 0.622
CLV_NRD_NRD_1 687 689 PF00675 0.597
CLV_PCSK_FUR_1 558 562 PF00082 0.594
CLV_PCSK_KEX2_1 199 201 PF00082 0.686
CLV_PCSK_KEX2_1 218 220 PF00082 0.515
CLV_PCSK_KEX2_1 265 267 PF00082 0.523
CLV_PCSK_KEX2_1 560 562 PF00082 0.594
CLV_PCSK_KEX2_1 625 627 PF00082 0.669
CLV_PCSK_KEX2_1 687 689 PF00082 0.597
CLV_PCSK_KEX2_1 737 739 PF00082 0.592
CLV_PCSK_KEX2_1 99 101 PF00082 0.641
CLV_PCSK_PC1ET2_1 199 201 PF00082 0.616
CLV_PCSK_PC1ET2_1 218 220 PF00082 0.511
CLV_PCSK_PC1ET2_1 265 267 PF00082 0.533
CLV_PCSK_PC1ET2_1 560 562 PF00082 0.594
CLV_PCSK_PC1ET2_1 737 739 PF00082 0.592
CLV_PCSK_PC1ET2_1 99 101 PF00082 0.641
CLV_PCSK_PC7_1 262 268 PF00082 0.562
CLV_PCSK_SKI1_1 241 245 PF00082 0.572
CLV_PCSK_SKI1_1 252 256 PF00082 0.493
CLV_PCSK_SKI1_1 262 266 PF00082 0.451
CLV_PCSK_SKI1_1 421 425 PF00082 0.614
CLV_PCSK_SKI1_1 49 53 PF00082 0.386
CLV_PCSK_SKI1_1 551 555 PF00082 0.596
CLV_PCSK_SKI1_1 590 594 PF00082 0.661
CLV_PCSK_SKI1_1 652 656 PF00082 0.647
CLV_Separin_Metazoa 364 368 PF03568 0.703
DEG_Kelch_Keap1_1 531 536 PF01344 0.653
DEG_SCF_FBW7_2 605 612 PF00400 0.657
DEG_SPOP_SBC_1 537 541 PF00917 0.596
DOC_CKS1_1 461 466 PF01111 0.606
DOC_CYCLIN_RxL_1 250 259 PF00134 0.479
DOC_MAPK_gen_1 687 693 PF00069 0.615
DOC_MAPK_gen_1 79 89 PF00069 0.339
DOC_PP2B_LxvP_1 194 197 PF13499 0.604
DOC_PP4_FxxP_1 98 101 PF00568 0.631
DOC_USP7_MATH_1 103 107 PF00917 0.577
DOC_USP7_MATH_1 125 129 PF00917 0.620
DOC_USP7_MATH_1 179 183 PF00917 0.555
DOC_USP7_MATH_1 211 215 PF00917 0.690
DOC_USP7_MATH_1 228 232 PF00917 0.507
DOC_USP7_MATH_1 243 247 PF00917 0.413
DOC_USP7_MATH_1 354 358 PF00917 0.682
DOC_USP7_MATH_1 441 445 PF00917 0.643
DOC_USP7_MATH_1 459 463 PF00917 0.595
DOC_USP7_MATH_1 471 475 PF00917 0.630
DOC_USP7_MATH_1 523 527 PF00917 0.644
DOC_USP7_MATH_1 537 541 PF00917 0.533
DOC_USP7_MATH_1 571 575 PF00917 0.636
DOC_USP7_MATH_1 592 596 PF00917 0.690
DOC_USP7_MATH_1 650 654 PF00917 0.603
DOC_USP7_MATH_1 713 717 PF00917 0.559
DOC_USP7_MATH_2 230 236 PF00917 0.579
DOC_USP7_UBL2_3 195 199 PF12436 0.609
DOC_WW_Pin1_4 16 21 PF00397 0.653
DOC_WW_Pin1_4 319 324 PF00397 0.546
DOC_WW_Pin1_4 333 338 PF00397 0.526
DOC_WW_Pin1_4 396 401 PF00397 0.667
DOC_WW_Pin1_4 427 432 PF00397 0.631
DOC_WW_Pin1_4 457 462 PF00397 0.726
DOC_WW_Pin1_4 467 472 PF00397 0.611
DOC_WW_Pin1_4 596 601 PF00397 0.671
DOC_WW_Pin1_4 605 610 PF00397 0.632
LIG_14-3-3_CanoR_1 200 204 PF00244 0.686
LIG_14-3-3_CanoR_1 24 29 PF00244 0.522
LIG_14-3-3_CanoR_1 241 251 PF00244 0.501
LIG_14-3-3_CanoR_1 302 306 PF00244 0.520
LIG_14-3-3_CanoR_1 329 337 PF00244 0.597
LIG_14-3-3_CanoR_1 406 413 PF00244 0.631
LIG_14-3-3_CanoR_1 419 426 PF00244 0.612
LIG_14-3-3_CanoR_1 521 529 PF00244 0.622
LIG_14-3-3_CanoR_1 712 718 PF00244 0.559
LIG_Actin_WH2_2 189 206 PF00022 0.599
LIG_BIR_III_2 227 231 PF00653 0.587
LIG_BIR_III_2 410 414 PF00653 0.646
LIG_BIR_III_2 597 601 PF00653 0.586
LIG_BRCT_BRCA1_1 702 706 PF00533 0.590
LIG_CtBP_PxDLS_1 311 315 PF00389 0.494
LIG_deltaCOP1_diTrp_1 285 290 PF00928 0.538
LIG_eIF4E_1 47 53 PF01652 0.375
LIG_FHA_1 175 181 PF00498 0.499
LIG_FHA_1 35 41 PF00498 0.380
LIG_FHA_1 734 740 PF00498 0.579
LIG_FHA_2 293 299 PF00498 0.464
LIG_FHA_2 37 43 PF00498 0.368
LIG_FHA_2 422 428 PF00498 0.632
LIG_FHA_2 528 534 PF00498 0.660
LIG_LIR_Apic_2 348 354 PF02991 0.677
LIG_LIR_Apic_2 485 491 PF02991 0.609
LIG_LIR_Gen_1 27 34 PF02991 0.406
LIG_LIR_Gen_1 711 722 PF02991 0.523
LIG_LIR_Nem_3 117 123 PF02991 0.614
LIG_LIR_Nem_3 148 152 PF02991 0.566
LIG_LIR_Nem_3 27 32 PF02991 0.406
LIG_LIR_Nem_3 285 290 PF02991 0.637
LIG_LIR_Nem_3 44 50 PF02991 0.227
LIG_LIR_Nem_3 711 717 PF02991 0.533
LIG_Pex14_2 729 733 PF04695 0.536
LIG_SH2_CRK 112 116 PF00017 0.615
LIG_SH2_CRK 29 33 PF00017 0.410
LIG_SH2_CRK 47 51 PF00017 0.220
LIG_SH2_CRK 714 718 PF00017 0.553
LIG_SH2_CRK 85 89 PF00017 0.496
LIG_SH2_NCK_1 529 533 PF00017 0.625
LIG_SH2_PTP2 488 491 PF00017 0.598
LIG_SH2_SRC 488 491 PF00017 0.598
LIG_SH2_STAP1 112 116 PF00017 0.615
LIG_SH2_STAP1 121 125 PF00017 0.524
LIG_SH2_STAP1 685 689 PF00017 0.598
LIG_SH2_STAP1 85 89 PF00017 0.496
LIG_SH2_STAT3 281 284 PF00017 0.555
LIG_SH2_STAT5 281 284 PF00017 0.555
LIG_SH2_STAT5 488 491 PF00017 0.598
LIG_SH2_STAT5 529 532 PF00017 0.624
LIG_SH3_1 618 624 PF00018 0.726
LIG_SH3_2 621 626 PF14604 0.657
LIG_SH3_3 104 110 PF00018 0.641
LIG_SH3_3 455 461 PF00018 0.714
LIG_SH3_3 462 468 PF00018 0.653
LIG_SH3_3 477 483 PF00018 0.537
LIG_SH3_3 50 56 PF00018 0.404
LIG_SH3_3 618 624 PF00018 0.719
LIG_SH3_CIN85_PxpxPR_1 16 21 PF14604 0.602
LIG_TRAF2_1 322 325 PF00917 0.534
LIG_TRAF2_1 39 42 PF00917 0.410
LIG_TRAF2_1 507 510 PF00917 0.593
LIG_UBA3_1 193 199 PF00899 0.569
LIG_WRC_WIRS_1 730 735 PF05994 0.545
LIG_WW_2 621 624 PF00397 0.614
MOD_CDC14_SPxK_1 599 602 PF00782 0.726
MOD_CDK_SPK_2 16 21 PF00069 0.602
MOD_CDK_SPxK_1 596 602 PF00069 0.726
MOD_CK1_1 19 25 PF00069 0.665
MOD_CK1_1 202 208 PF00069 0.699
MOD_CK1_1 235 241 PF00069 0.623
MOD_CK1_1 292 298 PF00069 0.463
MOD_CK1_1 395 401 PF00069 0.669
MOD_CK1_1 444 450 PF00069 0.706
MOD_CK1_1 460 466 PF00069 0.559
MOD_CK1_1 493 499 PF00069 0.702
MOD_CK1_1 531 537 PF00069 0.645
MOD_CK1_1 596 602 PF00069 0.656
MOD_CK2_1 292 298 PF00069 0.526
MOD_CK2_1 319 325 PF00069 0.535
MOD_CK2_1 358 364 PF00069 0.689
MOD_CK2_1 36 42 PF00069 0.410
MOD_CK2_1 421 427 PF00069 0.640
MOD_CK2_1 467 473 PF00069 0.685
MOD_CK2_1 527 533 PF00069 0.662
MOD_Cter_Amidation 216 219 PF01082 0.577
MOD_GlcNHglycan 162 165 PF01048 0.570
MOD_GlcNHglycan 213 216 PF01048 0.707
MOD_GlcNHglycan 235 238 PF01048 0.636
MOD_GlcNHglycan 394 397 PF01048 0.684
MOD_GlcNHglycan 421 424 PF01048 0.651
MOD_GlcNHglycan 443 446 PF01048 0.680
MOD_GlcNHglycan 473 477 PF01048 0.662
MOD_GlcNHglycan 525 528 PF01048 0.680
MOD_GlcNHglycan 530 533 PF01048 0.620
MOD_GlcNHglycan 567 570 PF01048 0.696
MOD_GlcNHglycan 651 655 PF01048 0.634
MOD_GSK3_1 141 148 PF00069 0.491
MOD_GSK3_1 174 181 PF00069 0.602
MOD_GSK3_1 198 205 PF00069 0.689
MOD_GSK3_1 228 235 PF00069 0.581
MOD_GSK3_1 288 295 PF00069 0.461
MOD_GSK3_1 32 39 PF00069 0.410
MOD_GSK3_1 328 335 PF00069 0.630
MOD_GSK3_1 341 348 PF00069 0.535
MOD_GSK3_1 354 361 PF00069 0.545
MOD_GSK3_1 392 399 PF00069 0.642
MOD_GSK3_1 421 428 PF00069 0.636
MOD_GSK3_1 467 474 PF00069 0.685
MOD_GSK3_1 489 496 PF00069 0.673
MOD_GSK3_1 512 519 PF00069 0.660
MOD_GSK3_1 523 530 PF00069 0.576
MOD_GSK3_1 538 545 PF00069 0.540
MOD_GSK3_1 586 593 PF00069 0.660
MOD_GSK3_1 601 608 PF00069 0.596
MOD_GSK3_1 693 700 PF00069 0.626
MOD_GSK3_1 729 736 PF00069 0.544
MOD_N-GLC_1 32 37 PF02516 0.410
MOD_N-GLC_1 697 702 PF02516 0.600
MOD_NEK2_1 130 135 PF00069 0.582
MOD_NEK2_1 178 183 PF00069 0.513
MOD_NEK2_1 186 191 PF00069 0.514
MOD_NEK2_1 198 203 PF00069 0.474
MOD_NEK2_1 301 306 PF00069 0.596
MOD_NEK2_1 32 37 PF00069 0.410
MOD_NEK2_1 345 350 PF00069 0.675
MOD_NEK2_1 542 547 PF00069 0.634
MOD_NEK2_1 565 570 PF00069 0.594
MOD_NEK2_1 693 698 PF00069 0.634
MOD_NEK2_1 729 734 PF00069 0.539
MOD_NEK2_2 179 184 PF00069 0.514
MOD_NMyristoyl 1 7 PF02799 0.640
MOD_PIKK_1 490 496 PF00454 0.624
MOD_PIKK_1 698 704 PF00454 0.630
MOD_PIKK_1 74 80 PF00454 0.313
MOD_PKA_1 199 205 PF00069 0.690
MOD_PKA_2 199 205 PF00069 0.686
MOD_PKA_2 221 227 PF00069 0.644
MOD_PKA_2 232 238 PF00069 0.524
MOD_PKA_2 301 307 PF00069 0.522
MOD_PKA_2 328 334 PF00069 0.590
MOD_PKA_2 405 411 PF00069 0.623
MOD_PKB_1 419 427 PF00069 0.610
MOD_Plk_1 581 587 PF00069 0.621
MOD_Plk_1 693 699 PF00069 0.636
MOD_Plk_2-3 273 279 PF00069 0.451
MOD_Plk_2-3 358 364 PF00069 0.689
MOD_Plk_4 103 109 PF00069 0.646
MOD_Plk_4 145 151 PF00069 0.522
MOD_Plk_4 24 30 PF00069 0.547
MOD_Plk_4 346 352 PF00069 0.660
MOD_Plk_4 484 490 PF00069 0.616
MOD_ProDKin_1 16 22 PF00069 0.646
MOD_ProDKin_1 319 325 PF00069 0.546
MOD_ProDKin_1 333 339 PF00069 0.528
MOD_ProDKin_1 396 402 PF00069 0.670
MOD_ProDKin_1 427 433 PF00069 0.635
MOD_ProDKin_1 457 463 PF00069 0.726
MOD_ProDKin_1 467 473 PF00069 0.615
MOD_ProDKin_1 596 602 PF00069 0.673
MOD_ProDKin_1 605 611 PF00069 0.632
MOD_SUMO_for_1 271 274 PF00179 0.510
MOD_SUMO_for_1 579 582 PF00179 0.617
MOD_SUMO_rev_2 612 619 PF00179 0.687
TRG_DiLeu_BaEn_3 724 730 PF01217 0.530
TRG_DiLeu_BaEn_4 277 283 PF01217 0.449
TRG_DiLeu_BaLyEn_6 334 339 PF01217 0.609
TRG_ENDOCYTIC_2 112 115 PF00928 0.607
TRG_ENDOCYTIC_2 159 162 PF00928 0.530
TRG_ENDOCYTIC_2 29 32 PF00928 0.410
TRG_ENDOCYTIC_2 47 50 PF00928 0.220
TRG_ENDOCYTIC_2 714 717 PF00928 0.560
TRG_ENDOCYTIC_2 73 76 PF00928 0.410
TRG_ENDOCYTIC_2 85 88 PF00928 0.376
TRG_ER_diArg_1 266 268 PF00400 0.530
TRG_ER_diArg_1 418 421 PF00400 0.646
TRG_ER_diArg_1 624 626 PF00400 0.660
TRG_ER_diArg_1 675 678 PF00400 0.639
TRG_ER_diLys_1 735 740 PF00400 0.583

Homologs

Protein Taxonomy Sequence identity Coverage
A4H933 Leishmania braziliensis 56% 93%
A4I5K6 Leishmania infantum 99% 100%
E9B0V1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 80% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS