LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein
Species:
Leishmania donovani
UniProt:
A0A3S7X3K2_LEIDO
TriTrypDb:
LdCL_300026300 , LDHU3_30.2850
Length:
223

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 2
NetGPI no yes: 0, no: 2
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X3K2
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X3K2

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 212 214 PF00675 0.501
CLV_PCSK_KEX2_1 212 214 PF00082 0.501
CLV_PCSK_KEX2_1 96 98 PF00082 0.526
CLV_PCSK_PC1ET2_1 96 98 PF00082 0.526
CLV_PCSK_SKI1_1 104 108 PF00082 0.504
DEG_MDM2_SWIB_1 139 147 PF02201 0.514
DEG_Nend_Nbox_1 1 3 PF02207 0.513
DEG_SCF_FBW7_1 65 72 PF00400 0.540
DEG_SPOP_SBC_1 163 167 PF00917 0.547
DEG_SPOP_SBC_1 31 35 PF00917 0.520
DOC_CYCLIN_yCln2_LP_2 147 153 PF00134 0.534
DOC_SPAK_OSR1_1 184 188 PF12202 0.599
DOC_USP7_MATH_1 23 27 PF00917 0.500
DOC_USP7_MATH_1 30 34 PF00917 0.537
DOC_USP7_MATH_1 69 73 PF00917 0.636
DOC_WW_Pin1_4 212 217 PF00397 0.515
DOC_WW_Pin1_4 63 68 PF00397 0.538
LIG_14-3-3_CanoR_1 104 113 PF00244 0.520
LIG_14-3-3_CanoR_1 25 29 PF00244 0.593
LIG_14-3-3_CanoR_1 80 85 PF00244 0.490
LIG_BRCT_BRCA1_1 166 170 PF00533 0.600
LIG_CAP-Gly_1 218 223 PF01302 0.494
LIG_FHA_1 176 182 PF00498 0.496
LIG_FHA_1 72 78 PF00498 0.524
LIG_LIR_Gen_1 107 116 PF02991 0.474
LIG_LIR_Nem_3 107 113 PF02991 0.474
LIG_LIR_Nem_3 61 65 PF02991 0.543
LIG_LYPXL_yS_3 179 182 PF13949 0.552
LIG_LYPXL_yS_3 62 65 PF13949 0.540
LIG_PDZ_Class_2 218 223 PF00595 0.548
LIG_Pex14_2 139 143 PF04695 0.483
LIG_SH2_CRK 39 43 PF00017 0.461
LIG_SH2_NCK_1 39 43 PF00017 0.461
LIG_SH3_3 197 203 PF00018 0.471
LIG_SH3_3 61 67 PF00018 0.542
LIG_TRAF2_1 117 120 PF00917 0.508
MOD_CK1_1 164 170 PF00069 0.560
MOD_CK2_1 112 118 PF00069 0.499
MOD_GlcNHglycan 159 162 PF01048 0.512
MOD_GlcNHglycan 188 191 PF01048 0.575
MOD_GSK3_1 157 164 PF00069 0.532
MOD_GSK3_1 65 72 PF00069 0.686
MOD_GSK3_1 82 89 PF00069 0.404
MOD_NEK2_1 112 117 PF00069 0.514
MOD_NEK2_1 17 22 PF00069 0.512
MOD_NEK2_2 24 29 PF00069 0.539
MOD_PIKK_1 165 171 PF00454 0.502
MOD_PIKK_1 82 88 PF00454 0.496
MOD_PKA_2 17 23 PF00069 0.513
MOD_PKA_2 24 30 PF00069 0.535
MOD_Plk_4 191 197 PF00069 0.601
MOD_ProDKin_1 212 218 PF00069 0.517
MOD_ProDKin_1 63 69 PF00069 0.535
TRG_DiLeu_BaEn_1 108 113 PF01217 0.498
TRG_DiLeu_BaEn_4 119 125 PF01217 0.507
TRG_ENDOCYTIC_2 136 139 PF00928 0.474
TRG_ENDOCYTIC_2 179 182 PF00928 0.746
TRG_ENDOCYTIC_2 62 65 PF00928 0.540
TRG_ER_diArg_1 211 213 PF00400 0.505

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1PED9 Leptomonas seymouri 40% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS