ATP-dependent DEAD/H DNA helicase recQ family-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP-dependent DEAD/H DNA helicase recQ family- like protein

Species:

Leishmania donovani

UniProt:

A0A3S7X3I6_LEIDO

TriTrypDb:

LdBPK_302300.1 , LdCL_300028500 , LDHU3_30.3120

Length:

1003

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 9
NetGPI	no	yes: 0, no: 9

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0005694	chromosome	5	1
GO:0005737	cytoplasm	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043228	non-membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0043232	intracellular non-membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3S7X3I6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X3I6

Function

Biological processes
Term	Name	Level	Count
GO:0000724	double-strand break repair via homologous recombination	7	1
GO:0000725	recombinational repair	6	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006259	DNA metabolic process	4	1
GO:0006268	DNA unwinding involved in DNA replication	9	1
GO:0006281	DNA repair	5	1
GO:0006302	double-strand break repair	6	1
GO:0006310	DNA recombination	5	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0006950	response to stress	2	1
GO:0006974	DNA damage response	4	1
GO:0006996	organelle organization	4	1
GO:0008152	metabolic process	1	1
GO:0009987	cellular process	1	1
GO:0016043	cellular component organization	3	1
GO:0032392	DNA geometric change	7	1
GO:0032508	DNA duplex unwinding	8	1
GO:0033554	cellular response to stress	3	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0046483	heterocycle metabolic process	3	1
GO:0050896	response to stimulus	1	1
GO:0051276	chromosome organization	5	1
GO:0051716	cellular response to stimulus	2	1
GO:0071103	DNA conformation change	6	1
GO:0071704	organic substance metabolic process	2	1
GO:0071840	cellular component organization or biogenesis	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	10
GO:0003676	nucleic acid binding	3	10
GO:0003824	catalytic activity	1	10
GO:0004386	helicase activity	2	10
GO:0005488	binding	1	10
GO:0005524	ATP binding	5	10
GO:0017076	purine nucleotide binding	4	10
GO:0030554	adenyl nucleotide binding	5	10
GO:0032553	ribonucleotide binding	3	10
GO:0032555	purine ribonucleotide binding	4	10
GO:0032559	adenyl ribonucleotide binding	5	10
GO:0035639	purine ribonucleoside triphosphate binding	4	10
GO:0036094	small molecule binding	2	10
GO:0043167	ion binding	2	10
GO:0043168	anion binding	3	10
GO:0097159	organic cyclic compound binding	2	10
GO:0097367	carbohydrate derivative binding	2	10
GO:0140640	catalytic activity, acting on a nucleic acid	2	10
GO:0140657	ATP-dependent activity	1	10
GO:1901265	nucleoside phosphate binding	3	10
GO:1901363	heterocyclic compound binding	2	10
GO:0003678	DNA helicase activity	3	2
GO:0008094	ATP-dependent activity, acting on DNA	2	2
GO:0009378	four-way junction helicase activity	4	1
GO:0043138	3'-5' DNA helicase activity	4	1
GO:0140097	catalytic activity, acting on DNA	3	2
GO:0016787	hydrolase activity	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	419	423	PF00656	0.494
CLV_C14_Caspase3-7	454	458	PF00656	0.400
CLV_C14_Caspase3-7	835	839	PF00656	0.474
CLV_NRD_NRD_1	11	13	PF00675	0.739
CLV_NRD_NRD_1	16	18	PF00675	0.681
CLV_NRD_NRD_1	294	296	PF00675	0.306
CLV_NRD_NRD_1	750	752	PF00675	0.669
CLV_NRD_NRD_1	872	874	PF00675	0.503
CLV_PCSK_KEX2_1	16	18	PF00082	0.613
CLV_PCSK_KEX2_1	294	296	PF00082	0.306
CLV_PCSK_KEX2_1	748	750	PF00082	0.639
CLV_PCSK_KEX2_1	872	874	PF00082	0.507
CLV_PCSK_PC1ET2_1	748	750	PF00082	0.639
CLV_PCSK_PC7_1	12	18	PF00082	0.607
CLV_PCSK_SKI1_1	169	173	PF00082	0.260
CLV_PCSK_SKI1_1	17	21	PF00082	0.664
CLV_PCSK_SKI1_1	294	298	PF00082	0.262
CLV_PCSK_SKI1_1	303	307	PF00082	0.262
CLV_PCSK_SKI1_1	355	359	PF00082	0.485
CLV_PCSK_SKI1_1	372	376	PF00082	0.372
CLV_PCSK_SKI1_1	386	390	PF00082	0.342
CLV_PCSK_SKI1_1	51	55	PF00082	0.593
CLV_PCSK_SKI1_1	544	548	PF00082	0.332
CLV_PCSK_SKI1_1	549	553	PF00082	0.332
CLV_PCSK_SKI1_1	636	640	PF00082	0.395
CLV_PCSK_SKI1_1	649	653	PF00082	0.421
CLV_PCSK_SKI1_1	872	876	PF00082	0.493
CLV_PCSK_SKI1_1	943	947	PF00082	0.506
DEG_APCC_DBOX_1	302	310	PF00400	0.507
DEG_APCC_DBOX_1	354	362	PF00400	0.468
DEG_APCC_DBOX_1	648	656	PF00400	0.420
DEG_MDM2_SWIB_1	982	990	PF02201	0.464
DOC_CDC14_PxL_1	358	366	PF14671	0.420
DOC_CYCLIN_RxL_1	291	299	PF00134	0.462
DOC_CYCLIN_yCln2_LP_2	270	276	PF00134	0.492
DOC_CYCLIN_yCln2_LP_2	338	344	PF00134	0.526
DOC_CYCLIN_yCln2_LP_2	444	450	PF00134	0.355
DOC_CYCLIN_yCln2_LP_2	608	614	PF00134	0.336
DOC_MAPK_FxFP_2	161	164	PF00069	0.518
DOC_MAPK_gen_1	131	139	PF00069	0.292
DOC_MAPK_gen_1	825	834	PF00069	0.415
DOC_MAPK_MEF2A_6	133	141	PF00069	0.453
DOC_MAPK_MEF2A_6	395	402	PF00069	0.478
DOC_MAPK_MEF2A_6	828	836	PF00069	0.383
DOC_MAPK_NFAT4_5	395	403	PF00069	0.460
DOC_MAPK_RevD_3	280	295	PF00069	0.532
DOC_PP1_RVXF_1	155	162	PF00149	0.471
DOC_PP1_RVXF_1	167	173	PF00149	0.461
DOC_PP2B_LxvP_1	45	48	PF13499	0.805
DOC_PP2B_LxvP_1	699	702	PF13499	0.468
DOC_PP2B_LxvP_1	801	804	PF13499	0.527
DOC_PP2B_LxvP_1	996	999	PF13499	0.571
DOC_PP4_FxxP_1	161	164	PF00568	0.475
DOC_PP4_FxxP_1	281	284	PF00568	0.449
DOC_SPAK_OSR1_1	224	228	PF12202	0.492
DOC_USP7_MATH_1	143	147	PF00917	0.409
DOC_USP7_MATH_1	190	194	PF00917	0.453
DOC_USP7_MATH_1	416	420	PF00917	0.587
DOC_USP7_MATH_1	475	479	PF00917	0.744
DOC_USP7_MATH_1	694	698	PF00917	0.538
DOC_USP7_MATH_1	702	706	PF00917	0.357
DOC_USP7_MATH_1	851	855	PF00917	0.548
DOC_USP7_MATH_1	92	96	PF00917	0.537
DOC_USP7_MATH_2	628	634	PF00917	0.418
DOC_WW_Pin1_4	227	232	PF00397	0.462
DOC_WW_Pin1_4	269	274	PF00397	0.449
DOC_WW_Pin1_4	280	285	PF00397	0.449
DOC_WW_Pin1_4	332	337	PF00397	0.581
DOC_WW_Pin1_4	471	476	PF00397	0.732
DOC_WW_Pin1_4	498	503	PF00397	0.659
DOC_WW_Pin1_4	624	629	PF00397	0.406
DOC_WW_Pin1_4	692	697	PF00397	0.701
DOC_WW_Pin1_4	742	747	PF00397	0.733
DOC_WW_Pin1_4	785	790	PF00397	0.508
DOC_WW_Pin1_4	842	847	PF00397	0.459
DOC_WW_Pin1_4	96	101	PF00397	0.639
DOC_WW_Pin1_4	970	975	PF00397	0.482
DOC_WW_Pin1_4	997	1002	PF00397	0.600
LIG_14-3-3_CanoR_1	181	187	PF00244	0.544
LIG_14-3-3_CanoR_1	295	304	PF00244	0.483
LIG_14-3-3_CanoR_1	386	394	PF00244	0.403
LIG_14-3-3_CanoR_1	408	413	PF00244	0.526
LIG_14-3-3_CanoR_1	431	438	PF00244	0.461
LIG_14-3-3_CanoR_1	51	58	PF00244	0.612
LIG_14-3-3_CanoR_1	544	552	PF00244	0.467
LIG_14-3-3_CanoR_1	636	646	PF00244	0.467
LIG_14-3-3_CanoR_1	828	836	PF00244	0.458
LIG_14-3-3_CanoR_1	872	878	PF00244	0.510
LIG_14-3-3_CanoR_1	934	940	PF00244	0.522
LIG_14-3-3_CanoR_1	949	954	PF00244	0.595
LIG_AP2alpha_2	392	394	PF02296	0.353
LIG_BIR_II_1	1	5	PF00653	0.614
LIG_BIR_III_4	505	509	PF00653	0.639
LIG_BRCT_BRCA1_1	157	161	PF00533	0.471
LIG_BRCT_BRCA1_1	484	488	PF00533	0.658
LIG_BRCT_BRCA1_1	972	976	PF00533	0.484
LIG_Clathr_ClatBox_1	306	310	PF01394	0.507
LIG_DLG_GKlike_1	408	415	PF00625	0.542
LIG_EH_1	609	613	PF12763	0.365
LIG_FHA_1	145	151	PF00498	0.449
LIG_FHA_1	369	375	PF00498	0.440
LIG_FHA_1	401	407	PF00498	0.564
LIG_FHA_1	677	683	PF00498	0.511
LIG_FHA_1	753	759	PF00498	0.585
LIG_FHA_1	776	782	PF00498	0.488
LIG_FHA_1	979	985	PF00498	0.553
LIG_FHA_2	13	19	PF00498	0.742
LIG_FHA_2	387	393	PF00498	0.333
LIG_FHA_2	75	81	PF00498	0.466
LIG_GBD_Chelix_1	559	567	PF00786	0.307
LIG_LIR_Apic_2	158	164	PF02991	0.469
LIG_LIR_Apic_2	278	284	PF02991	0.449
LIG_LIR_Apic_2	907	911	PF02991	0.617
LIG_LIR_Gen_1	223	233	PF02991	0.482
LIG_LIR_Gen_1	325	333	PF02991	0.449
LIG_LIR_Gen_1	411	418	PF02991	0.564
LIG_LIR_Gen_1	671	682	PF02991	0.372
LIG_LIR_Gen_1	937	946	PF02991	0.519
LIG_LIR_Nem_3	223	228	PF02991	0.477
LIG_LIR_Nem_3	325	329	PF02991	0.462
LIG_LIR_Nem_3	381	385	PF02991	0.459
LIG_LIR_Nem_3	411	415	PF02991	0.567
LIG_LIR_Nem_3	613	617	PF02991	0.411
LIG_LIR_Nem_3	671	677	PF02991	0.330
LIG_LIR_Nem_3	713	717	PF02991	0.450
LIG_LIR_Nem_3	937	942	PF02991	0.502
LIG_LIR_Nem_3	973	979	PF02991	0.476
LIG_MAD2	265	273	PF02301	0.471
LIG_MLH1_MIPbox_1	972	976	PF16413	0.509
LIG_NRBOX	460	466	PF00104	0.506
LIG_NRBOX	672	678	PF00104	0.394
LIG_NRBOX	941	947	PF00104	0.574
LIG_PCNA_PIPBox_1	849	858	PF02747	0.503
LIG_Pex14_1	318	322	PF04695	0.449
LIG_Pex14_2	322	326	PF04695	0.449
LIG_Pex14_2	982	986	PF04695	0.476
LIG_PTB_Apo_2	969	976	PF02174	0.595
LIG_PTB_Phospho_1	969	975	PF10480	0.597
LIG_SH2_CRK	714	718	PF00017	0.429
LIG_SH2_GRB2like	970	973	PF00017	0.583
LIG_SH2_SRC	970	973	PF00017	0.608
LIG_SH2_STAT3	806	809	PF00017	0.331
LIG_SH2_STAT3	959	962	PF00017	0.624
LIG_SH2_STAT5	117	120	PF00017	0.375
LIG_SH2_STAT5	176	179	PF00017	0.507
LIG_SH2_STAT5	328	331	PF00017	0.449
LIG_SH2_STAT5	363	366	PF00017	0.521
LIG_SH2_STAT5	451	454	PF00017	0.377
LIG_SH2_STAT5	589	592	PF00017	0.449
LIG_SH2_STAT5	615	618	PF00017	0.384
LIG_SH2_STAT5	970	973	PF00017	0.504
LIG_SH2_STAT5	975	978	PF00017	0.506
LIG_SH3_1	786	792	PF00018	0.365
LIG_SH3_3	225	231	PF00018	0.512
LIG_SH3_3	270	276	PF00018	0.492
LIG_SH3_3	520	526	PF00018	0.732
LIG_SH3_3	528	534	PF00018	0.581
LIG_SH3_3	62	68	PF00018	0.712
LIG_SH3_3	679	685	PF00018	0.624
LIG_SH3_3	786	792	PF00018	0.396
LIG_SH3_3	968	974	PF00018	0.477
LIG_SH3_3	987	993	PF00018	0.472
LIG_SH3_4	131	138	PF00018	0.383
LIG_SUMO_SIM_par_1	230	238	PF11976	0.492
LIG_SUMO_SIM_par_1	651	656	PF11976	0.357
LIG_SUMO_SIM_par_1	832	839	PF11976	0.387
LIG_TRAF2_1	345	348	PF00917	0.523
LIG_TYR_ITIM	361	366	PF00017	0.456
LIG_TYR_ITIM	712	717	PF00017	0.449
LIG_UBA3_1	82	91	PF00899	0.457
LIG_WRC_WIRS_1	979	984	PF05994	0.562
MOD_CDC14_SPxK_1	283	286	PF00782	0.449
MOD_CDC14_SPxK_1	695	698	PF00782	0.492
MOD_CDK_SPxK_1	280	286	PF00069	0.449
MOD_CDK_SPxK_1	692	698	PF00069	0.508
MOD_CDK_SPxK_1	742	748	PF00069	0.736
MOD_CDK_SPxxK_3	742	749	PF00069	0.644
MOD_CK1_1	101	107	PF00069	0.598
MOD_CK1_1	108	114	PF00069	0.484
MOD_CK1_1	193	199	PF00069	0.541
MOD_CK1_1	478	484	PF00069	0.684
MOD_CK1_1	52	58	PF00069	0.732
MOD_CK1_1	581	587	PF00069	0.449
MOD_CK1_1	60	66	PF00069	0.675
MOD_CK1_1	656	662	PF00069	0.432
MOD_CK1_1	692	698	PF00069	0.582
MOD_CK1_1	733	739	PF00069	0.708
MOD_CK2_1	581	587	PF00069	0.449
MOD_CK2_1	624	630	PF00069	0.387
MOD_CK2_1	74	80	PF00069	0.529
MOD_CK2_1	836	842	PF00069	0.471
MOD_CK2_1	934	940	PF00069	0.484
MOD_GlcNHglycan	103	106	PF01048	0.647
MOD_GlcNHglycan	107	110	PF01048	0.573
MOD_GlcNHglycan	207	210	PF01048	0.310
MOD_GlcNHglycan	214	217	PF01048	0.268
MOD_GlcNHglycan	249	252	PF01048	0.271
MOD_GlcNHglycan	254	257	PF01048	0.247
MOD_GlcNHglycan	29	32	PF01048	0.706
MOD_GlcNHglycan	315	318	PF01048	0.307
MOD_GlcNHglycan	416	419	PF01048	0.630
MOD_GlcNHglycan	427	431	PF01048	0.604
MOD_GlcNHglycan	461	464	PF01048	0.479
MOD_GlcNHglycan	477	480	PF01048	0.596
MOD_GlcNHglycan	484	487	PF01048	0.622
MOD_GlcNHglycan	51	54	PF01048	0.805
MOD_GlcNHglycan	544	547	PF01048	0.307
MOD_GlcNHglycan	580	583	PF01048	0.292
MOD_GlcNHglycan	59	62	PF01048	0.739
MOD_GlcNHglycan	641	644	PF01048	0.436
MOD_GlcNHglycan	655	658	PF01048	0.517
MOD_GlcNHglycan	733	736	PF01048	0.684
MOD_GlcNHglycan	762	765	PF01048	0.504
MOD_GlcNHglycan	817	820	PF01048	0.601
MOD_GlcNHglycan	829	832	PF01048	0.419
MOD_GSK3_1	101	108	PF00069	0.577
MOD_GSK3_1	182	189	PF00069	0.486
MOD_GSK3_1	364	371	PF00069	0.394
MOD_GSK3_1	426	433	PF00069	0.511
MOD_GSK3_1	459	466	PF00069	0.425
MOD_GSK3_1	469	476	PF00069	0.555
MOD_GSK3_1	47	54	PF00069	0.706
MOD_GSK3_1	478	485	PF00069	0.541
MOD_GSK3_1	578	585	PF00069	0.466
MOD_GSK3_1	626	633	PF00069	0.418
MOD_GSK3_1	637	644	PF00069	0.289
MOD_GSK3_1	688	695	PF00069	0.753
MOD_GSK3_1	815	822	PF00069	0.504
MOD_GSK3_1	92	99	PF00069	0.530
MOD_GSK3_1	978	985	PF00069	0.607
MOD_LATS_1	10	16	PF00433	0.595
MOD_N-GLC_1	736	741	PF02516	0.665
MOD_NEK2_1	118	123	PF00069	0.384
MOD_NEK2_1	19	24	PF00069	0.705
MOD_NEK2_1	212	217	PF00069	0.536
MOD_NEK2_1	252	257	PF00069	0.518
MOD_NEK2_1	287	292	PF00069	0.532
MOD_NEK2_1	296	301	PF00069	0.532
MOD_NEK2_1	327	332	PF00069	0.532
MOD_NEK2_1	364	369	PF00069	0.363
MOD_NEK2_1	464	469	PF00069	0.441
MOD_NEK2_1	539	544	PF00069	0.518
MOD_NEK2_1	559	564	PF00069	0.395
MOD_NEK2_1	621	626	PF00069	0.440
MOD_NEK2_1	639	644	PF00069	0.405
MOD_NEK2_1	651	656	PF00069	0.368
MOD_NEK2_1	675	680	PF00069	0.539
MOD_NEK2_1	731	736	PF00069	0.671
MOD_NEK2_1	758	763	PF00069	0.561
MOD_NEK2_1	815	820	PF00069	0.527
MOD_NEK2_1	965	970	PF00069	0.474
MOD_NEK2_1	982	987	PF00069	0.526
MOD_OFUCOSY	115	122	PF10250	0.317
MOD_PIKK_1	296	302	PF00454	0.486
MOD_PIKK_1	430	436	PF00454	0.474
MOD_PIKK_1	537	543	PF00454	0.485
MOD_PIKK_1	544	550	PF00454	0.451
MOD_PK_1	873	879	PF00069	0.399
MOD_PKA_1	12	18	PF00069	0.747
MOD_PKA_1	749	755	PF00069	0.722
MOD_PKA_2	174	180	PF00069	0.507
MOD_PKA_2	322	328	PF00069	0.449
MOD_PKA_2	430	436	PF00069	0.510
MOD_PKA_2	749	755	PF00069	0.724
MOD_PKA_2	827	833	PF00069	0.436
MOD_PKA_2	879	885	PF00069	0.519
MOD_PKB_1	932	940	PF00069	0.497
MOD_Plk_1	736	742	PF00069	0.664
MOD_Plk_1	982	988	PF00069	0.526
MOD_Plk_4	137	143	PF00069	0.492
MOD_Plk_4	322	328	PF00069	0.454
MOD_Plk_4	621	627	PF00069	0.381
MOD_Plk_4	630	636	PF00069	0.337
MOD_Plk_4	668	674	PF00069	0.387
MOD_Plk_4	919	925	PF00069	0.552
MOD_Plk_4	965	971	PF00069	0.492
MOD_Plk_4	982	988	PF00069	0.593
MOD_ProDKin_1	227	233	PF00069	0.462
MOD_ProDKin_1	269	275	PF00069	0.449
MOD_ProDKin_1	280	286	PF00069	0.449
MOD_ProDKin_1	332	338	PF00069	0.584
MOD_ProDKin_1	471	477	PF00069	0.736
MOD_ProDKin_1	498	504	PF00069	0.663
MOD_ProDKin_1	624	630	PF00069	0.403
MOD_ProDKin_1	692	698	PF00069	0.693
MOD_ProDKin_1	742	748	PF00069	0.734
MOD_ProDKin_1	785	791	PF00069	0.503
MOD_ProDKin_1	842	848	PF00069	0.454
MOD_ProDKin_1	96	102	PF00069	0.644
MOD_ProDKin_1	970	976	PF00069	0.479
MOD_ProDKin_1	997	1003	PF00069	0.609
TRG_DiLeu_BaEn_2	669	675	PF01217	0.330
TRG_DiLeu_BaLyEn_6	166	171	PF01217	0.492
TRG_DiLeu_BaLyEn_6	228	233	PF01217	0.449
TRG_DiLeu_BaLyEn_6	292	297	PF01217	0.519
TRG_DiLeu_BaLyEn_6	333	338	PF01217	0.517
TRG_DiLeu_BaLyEn_6	603	608	PF01217	0.338
TRG_ENDOCYTIC_2	363	366	PF00928	0.451
TRG_ENDOCYTIC_2	609	612	PF00928	0.401
TRG_ENDOCYTIC_2	714	717	PF00928	0.420
TRG_ENDOCYTIC_2	939	942	PF00928	0.512
TRG_ER_diArg_1	293	295	PF00400	0.506
TRG_ER_diArg_1	617	620	PF00400	0.365
TRG_ER_diArg_1	749	751	PF00400	0.709
TRG_ER_diArg_1	861	864	PF00400	0.449
TRG_ER_diArg_1	871	873	PF00400	0.430
TRG_ER_diArg_1	932	935	PF00400	0.455
TRG_ER_diArg_1	948	951	PF00400	0.508
TRG_NES_CRM1_1	557	570	PF08389	0.449
TRG_NLS_MonoCore_2	747	752	PF00514	0.725
TRG_NLS_MonoExtN_4	746	752	PF00514	0.671
TRG_Pf-PMV_PEXEL_1	169	173	PF00026	0.267
TRG_Pf-PMV_PEXEL_1	265	269	PF00026	0.320
TRG_Pf-PMV_PEXEL_1	294	298	PF00026	0.299
TRG_Pf-PMV_PEXEL_1	951	955	PF00026	0.591

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IMF3	Leptomonas seymouri	58%	91%
A0A1X0P1S1	Trypanosomatidae	43%	100%
A0A3R7L9G4	Trypanosoma rangeli	43%	100%
A4HIG1	Leishmania braziliensis	79%	100%
A4I5Q7	Leishmania infantum	99%	100%
C9ZR26	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	41%	100%
E9B102	Leishmania mexicana (strain MHOM/GT/2001/U1103)	91%	100%
Q4Q764	Leishmania major	92%	100%