Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S7X3F7_LEIDO

TriTrypDb:

LdBPK_302010.1 , LdCL_300025400

Length:

1019

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 1, no: 2
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X3F7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X3F7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	906	910	PF00656	0.590
CLV_NRD_NRD_1	13	15	PF00675	0.705
CLV_NRD_NRD_1	258	260	PF00675	0.594
CLV_NRD_NRD_1	273	275	PF00675	0.590
CLV_NRD_NRD_1	456	458	PF00675	0.640
CLV_NRD_NRD_1	536	538	PF00675	0.714
CLV_NRD_NRD_1	594	596	PF00675	0.596
CLV_NRD_NRD_1	625	627	PF00675	0.691
CLV_NRD_NRD_1	628	630	PF00675	0.677
CLV_NRD_NRD_1	673	675	PF00675	0.667
CLV_NRD_NRD_1	678	680	PF00675	0.666
CLV_NRD_NRD_1	974	976	PF00675	0.561
CLV_NRD_NRD_1	985	987	PF00675	0.478
CLV_PCSK_FUR_1	626	630	PF00082	0.617
CLV_PCSK_KEX2_1	111	113	PF00082	0.639
CLV_PCSK_KEX2_1	12	14	PF00082	0.709
CLV_PCSK_KEX2_1	128	130	PF00082	0.563
CLV_PCSK_KEX2_1	195	197	PF00082	0.642
CLV_PCSK_KEX2_1	258	260	PF00082	0.598
CLV_PCSK_KEX2_1	273	275	PF00082	0.594
CLV_PCSK_KEX2_1	458	460	PF00082	0.622
CLV_PCSK_KEX2_1	536	538	PF00082	0.714
CLV_PCSK_KEX2_1	594	596	PF00082	0.596
CLV_PCSK_KEX2_1	625	627	PF00082	0.695
CLV_PCSK_KEX2_1	628	630	PF00082	0.681
CLV_PCSK_KEX2_1	673	675	PF00082	0.667
CLV_PCSK_KEX2_1	678	680	PF00082	0.666
CLV_PCSK_KEX2_1	974	976	PF00082	0.562
CLV_PCSK_KEX2_1	984	986	PF00082	0.490
CLV_PCSK_PC1ET2_1	111	113	PF00082	0.597
CLV_PCSK_PC1ET2_1	128	130	PF00082	0.509
CLV_PCSK_PC1ET2_1	195	197	PF00082	0.642
CLV_PCSK_PC1ET2_1	458	460	PF00082	0.572
CLV_PCSK_PC7_1	532	538	PF00082	0.699
CLV_PCSK_PC7_1	674	680	PF00082	0.621
CLV_PCSK_SKI1_1	500	504	PF00082	0.556
CLV_PCSK_SKI1_1	697	701	PF00082	0.555
CLV_PCSK_SKI1_1	985	989	PF00082	0.557
CLV_Separin_Metazoa	768	772	PF03568	0.559
CLV_Separin_Metazoa	981	985	PF03568	0.471
DEG_SCF_FBW7_1	236	241	PF00400	0.609
DEG_SPOP_SBC_1	211	215	PF00917	0.638
DEG_SPOP_SBC_1	252	256	PF00917	0.586
DEG_SPOP_SBC_1	321	325	PF00917	0.661
DOC_CDC14_PxL_1	180	188	PF14671	0.647
DOC_CKS1_1	105	110	PF01111	0.606
DOC_CKS1_1	122	127	PF01111	0.487
DOC_CKS1_1	414	419	PF01111	0.671
DOC_CKS1_1	443	448	PF01111	0.608
DOC_CYCLIN_RxL_1	983	992	PF00134	0.551
DOC_CYCLIN_yCln2_LP_2	503	509	PF00134	0.559
DOC_MAPK_DCC_7	387	397	PF00069	0.645
DOC_MAPK_gen_1	1004	1012	PF00069	0.415
DOC_MAPK_gen_1	258	264	PF00069	0.572
DOC_MAPK_gen_1	984	990	PF00069	0.556
DOC_MAPK_MEF2A_6	705	712	PF00069	0.485
DOC_MAPK_NFAT4_5	705	713	PF00069	0.478
DOC_PP2B_LxvP_1	503	506	PF13499	0.551
DOC_PP2B_LxvP_1	897	900	PF13499	0.656
DOC_PP4_FxxP_1	502	505	PF00568	0.557
DOC_PP4_FxxP_1	808	811	PF00568	0.654
DOC_USP7_MATH_1	158	162	PF00917	0.633
DOC_USP7_MATH_1	211	215	PF00917	0.672
DOC_USP7_MATH_1	252	256	PF00917	0.586
DOC_USP7_MATH_1	283	287	PF00917	0.595
DOC_USP7_MATH_1	296	300	PF00917	0.563
DOC_USP7_MATH_1	321	325	PF00917	0.661
DOC_USP7_MATH_1	381	385	PF00917	0.581
DOC_USP7_MATH_1	420	424	PF00917	0.676
DOC_USP7_MATH_1	431	435	PF00917	0.579
DOC_USP7_MATH_1	449	453	PF00917	0.540
DOC_USP7_MATH_1	657	661	PF00917	0.626
DOC_USP7_MATH_1	664	668	PF00917	0.585
DOC_USP7_MATH_1	677	681	PF00917	0.522
DOC_USP7_MATH_1	782	786	PF00917	0.672
DOC_USP7_MATH_1	901	905	PF00917	0.585
DOC_USP7_MATH_1	929	933	PF00917	0.497
DOC_USP7_UBL2_3	447	451	PF12436	0.559
DOC_WW_Pin1_4	104	109	PF00397	0.621
DOC_WW_Pin1_4	121	126	PF00397	0.576
DOC_WW_Pin1_4	133	138	PF00397	0.592
DOC_WW_Pin1_4	234	239	PF00397	0.686
DOC_WW_Pin1_4	245	250	PF00397	0.599
DOC_WW_Pin1_4	37	42	PF00397	0.637
DOC_WW_Pin1_4	413	418	PF00397	0.670
DOC_WW_Pin1_4	442	447	PF00397	0.630
DOC_WW_Pin1_4	457	462	PF00397	0.577
DOC_WW_Pin1_4	620	625	PF00397	0.641
DOC_WW_Pin1_4	633	638	PF00397	0.640
DOC_WW_Pin1_4	68	73	PF00397	0.686
DOC_WW_Pin1_4	776	781	PF00397	0.573
DOC_WW_Pin1_4	824	829	PF00397	0.672
LIG_14-3-3_CanoR_1	100	108	PF00244	0.688
LIG_14-3-3_CanoR_1	121	125	PF00244	0.647
LIG_14-3-3_CanoR_1	129	135	PF00244	0.615
LIG_14-3-3_CanoR_1	242	252	PF00244	0.690
LIG_14-3-3_CanoR_1	326	334	PF00244	0.661
LIG_14-3-3_CanoR_1	617	623	PF00244	0.645
LIG_14-3-3_CanoR_1	629	635	PF00244	0.646
LIG_14-3-3_CanoR_1	642	651	PF00244	0.571
LIG_14-3-3_CanoR_1	75	82	PF00244	0.699
LIG_14-3-3_CanoR_1	879	886	PF00244	0.562
LIG_Actin_WH2_2	935	950	PF00022	0.554
LIG_AP2alpha_2	650	652	PF02296	0.652
LIG_BIR_II_1	1	5	PF00653	0.644
LIG_BIR_III_2	69	73	PF00653	0.693
LIG_BRCT_BRCA1_1	189	193	PF00533	0.555
LIG_BRCT_BRCA1_1	329	333	PF00533	0.579
LIG_BRCT_BRCA1_1	451	455	PF00533	0.695
LIG_BRCT_BRCA1_1	648	652	PF00533	0.582
LIG_BRCT_BRCA1_1	876	880	PF00533	0.657
LIG_BRCT_BRCA1_2	189	195	PF00533	0.557
LIG_FAT_LD_1	748	756	PF03623	0.573
LIG_FHA_1	152	158	PF00498	0.660
LIG_FHA_1	20	26	PF00498	0.661
LIG_FHA_1	213	219	PF00498	0.635
LIG_FHA_1	235	241	PF00498	0.692
LIG_FHA_1	246	252	PF00498	0.593
LIG_FHA_1	329	335	PF00498	0.656
LIG_FHA_1	346	352	PF00498	0.531
LIG_FHA_1	451	457	PF00498	0.694
LIG_FHA_1	791	797	PF00498	0.663
LIG_FHA_1	921	927	PF00498	0.533
LIG_FHA_2	154	160	PF00498	0.586
LIG_FHA_2	414	420	PF00498	0.669
LIG_FHA_2	729	735	PF00498	0.672
LIG_FHA_2	763	769	PF00498	0.560
LIG_FHA_2	901	907	PF00498	0.584
LIG_GBD_Chelix_1	51	59	PF00786	0.592
LIG_LIR_Apic_2	499	505	PF02991	0.553
LIG_LIR_Apic_2	60	66	PF02991	0.637
LIG_LIR_Apic_2	660	664	PF02991	0.597
LIG_LIR_Gen_1	220	228	PF02991	0.569
LIG_LIR_Gen_1	423	432	PF02991	0.667
LIG_LIR_Gen_1	763	773	PF02991	0.560
LIG_LIR_Gen_1	877	888	PF02991	0.645
LIG_LIR_Gen_1	932	942	PF02991	0.569
LIG_LIR_LC3C_4	393	397	PF02991	0.648
LIG_LIR_Nem_3	220	225	PF02991	0.569
LIG_LIR_Nem_3	261	267	PF02991	0.551
LIG_LIR_Nem_3	423	427	PF02991	0.676
LIG_LIR_Nem_3	763	769	PF02991	0.560
LIG_LIR_Nem_3	877	883	PF02991	0.652
LIG_LIR_Nem_3	932	937	PF02991	0.579
LIG_MLH1_MIPbox_1	189	193	PF16413	0.555
LIG_MLH1_MIPbox_1	329	333	PF16413	0.579
LIG_NRBOX	473	479	PF00104	0.549
LIG_NRBOX	708	714	PF00104	0.469
LIG_PCNA_PIPBox_1	56	65	PF02747	0.620
LIG_PCNA_yPIPBox_3	53	63	PF02747	0.608
LIG_PTAP_UEV_1	857	862	PF05743	0.656
LIG_Rb_LxCxE_1	21	40	PF01857	0.653
LIG_RPA_C_Fungi	224	236	PF08784	0.581
LIG_SH2_CRK	63	67	PF00017	0.655
LIG_SH2_STAP1	766	770	PF00017	0.529
LIG_SH2_STAP1	853	857	PF00017	0.574
LIG_SH2_STAT5	1005	1008	PF00017	0.547
LIG_SH2_STAT5	192	195	PF00017	0.641
LIG_SH2_STAT5	43	46	PF00017	0.542
LIG_SH2_STAT5	662	665	PF00017	0.560
LIG_SH3_2	446	451	PF14604	0.608
LIG_SH3_2	637	642	PF14604	0.679
LIG_SH3_3	136	142	PF00018	0.599
LIG_SH3_3	157	163	PF00018	0.664
LIG_SH3_3	197	203	PF00018	0.663
LIG_SH3_3	246	252	PF00018	0.638
LIG_SH3_3	303	309	PF00018	0.677
LIG_SH3_3	35	41	PF00018	0.639
LIG_SH3_3	408	414	PF00018	0.686
LIG_SH3_3	437	443	PF00018	0.647
LIG_SH3_3	598	604	PF00018	0.604
LIG_SH3_3	606	612	PF00018	0.693
LIG_SH3_3	631	637	PF00018	0.683
LIG_SH3_3	794	800	PF00018	0.674
LIG_SH3_3	801	807	PF00018	0.614
LIG_SH3_3	825	831	PF00018	0.668
LIG_SH3_3	855	861	PF00018	0.653
LIG_SH3_4	447	454	PF00018	0.559
LIG_SH3_CIN85_PxpxPR_1	637	642	PF14604	0.679
LIG_SUMO_SIM_par_1	393	399	PF11976	0.649
LIG_TRAF2_1	852	855	PF00917	0.654
LIG_TRAF2_1	904	907	PF00917	0.581
LIG_TRAF2_2	285	290	PF00917	0.691
LIG_TYR_ITIM	482	487	PF00017	0.491
LIG_UBA3_1	709	718	PF00899	0.472
LIG_WRC_WIRS_1	421	426	PF05994	0.679
LIG_WRC_WIRS_1	524	529	PF05994	0.561
LIG_WW_1	505	508	PF00397	0.558
LIG_WW_3	639	643	PF00397	0.672
MOD_CDK_SPK_2	442	447	PF00069	0.609
MOD_CDK_SPK_2	620	625	PF00069	0.607
MOD_CDK_SPK_2	68	73	PF00069	0.686
MOD_CDK_SPxK_1	620	626	PF00069	0.610
MOD_CDK_SPxxK_3	104	111	PF00069	0.618
MOD_CDK_SPxxK_3	121	128	PF00069	0.576
MOD_CDK_SPxxK_3	459	466	PF00069	0.600
MOD_CDK_SPxxK_3	68	75	PF00069	0.611
MOD_CK1_1	115	121	PF00069	0.669
MOD_CK1_1	133	139	PF00069	0.538
MOD_CK1_1	151	157	PF00069	0.532
MOD_CK1_1	212	218	PF00069	0.663
MOD_CK1_1	241	247	PF00069	0.649
MOD_CK1_1	319	325	PF00069	0.678
MOD_CK1_1	328	334	PF00069	0.643
MOD_CK1_1	399	405	PF00069	0.651
MOD_CK1_1	423	429	PF00069	0.668
MOD_CK1_1	450	456	PF00069	0.693
MOD_CK1_1	513	519	PF00069	0.560
MOD_CK1_1	522	528	PF00069	0.524
MOD_CK1_1	553	559	PF00069	0.674
MOD_CK1_1	633	639	PF00069	0.694
MOD_CK1_1	727	733	PF00069	0.666
MOD_CK1_1	737	743	PF00069	0.580
MOD_CK1_1	77	83	PF00069	0.708
MOD_CK1_1	776	782	PF00069	0.660
MOD_CK1_1	785	791	PF00069	0.604
MOD_CK1_1	827	833	PF00069	0.654
MOD_CK1_1	87	93	PF00069	0.625
MOD_CK1_1	881	887	PF00069	0.640
MOD_CK2_1	153	159	PF00069	0.590
MOD_CK2_1	498	504	PF00069	0.554
MOD_CK2_1	727	733	PF00069	0.666
MOD_CK2_1	762	768	PF00069	0.567
MOD_CK2_1	785	791	PF00069	0.679
MOD_CK2_1	827	833	PF00069	0.668
MOD_CK2_1	900	906	PF00069	0.582
MOD_Cter_Amidation	626	629	PF01082	0.706
MOD_DYRK1A_RPxSP_1	459	463	PF00069	0.602
MOD_GlcNHglycan	219	222	PF01048	0.566
MOD_GlcNHglycan	279	282	PF01048	0.631
MOD_GlcNHglycan	290	294	PF01048	0.608
MOD_GlcNHglycan	3	6	PF01048	0.691
MOD_GlcNHglycan	327	330	PF01048	0.668
MOD_GlcNHglycan	383	386	PF01048	0.667
MOD_GlcNHglycan	402	405	PF01048	0.513
MOD_GlcNHglycan	433	436	PF01048	0.682
MOD_GlcNHglycan	512	515	PF01048	0.560
MOD_GlcNHglycan	558	561	PF01048	0.667
MOD_GlcNHglycan	562	565	PF01048	0.620
MOD_GlcNHglycan	567	570	PF01048	0.571
MOD_GlcNHglycan	573	576	PF01048	0.549
MOD_GlcNHglycan	675	678	PF01048	0.686
MOD_GlcNHglycan	740	743	PF01048	0.659
MOD_GlcNHglycan	77	80	PF01048	0.712
MOD_GlcNHglycan	775	778	PF01048	0.620
MOD_GlcNHglycan	784	787	PF01048	0.628
MOD_GlcNHglycan	788	791	PF01048	0.569
MOD_GlcNHglycan	858	861	PF01048	0.650
MOD_GlcNHglycan	909	913	PF01048	0.615
MOD_GlcNHglycan	94	97	PF01048	0.563
MOD_GSK3_1	113	120	PF00069	0.612
MOD_GSK3_1	14	21	PF00069	0.639
MOD_GSK3_1	148	155	PF00069	0.621
MOD_GSK3_1	234	241	PF00069	0.657
MOD_GSK3_1	27	34	PF00069	0.547
MOD_GSK3_1	316	323	PF00069	0.661
MOD_GSK3_1	396	403	PF00069	0.652
MOD_GSK3_1	422	429	PF00069	0.670
MOD_GSK3_1	519	526	PF00069	0.560
MOD_GSK3_1	556	563	PF00069	0.663
MOD_GSK3_1	629	636	PF00069	0.613
MOD_GSK3_1	642	649	PF00069	0.550
MOD_GSK3_1	664	671	PF00069	0.646
MOD_GSK3_1	673	680	PF00069	0.610
MOD_GSK3_1	724	731	PF00069	0.654
MOD_GSK3_1	732	739	PF00069	0.609
MOD_GSK3_1	781	788	PF00069	0.688
MOD_GSK3_1	874	881	PF00069	0.653
MOD_GSK3_1	901	908	PF00069	0.589
MOD_GSK3_1	938	945	PF00069	0.475
MOD_GSK3_1	99	106	PF00069	0.643
MOD_LATS_1	548	554	PF00433	0.697
MOD_N-GLC_1	252	257	PF02516	0.586
MOD_NEK2_1	1	6	PF00069	0.681
MOD_NEK2_1	101	106	PF00069	0.692
MOD_NEK2_1	117	122	PF00069	0.524
MOD_NEK2_1	130	135	PF00069	0.575
MOD_NEK2_1	152	157	PF00069	0.681
MOD_NEK2_1	240	245	PF00069	0.654
MOD_NEK2_1	31	36	PF00069	0.650
MOD_NEK2_1	400	405	PF00069	0.653
MOD_NEK2_1	51	56	PF00069	0.421
MOD_NEK2_1	527	532	PF00069	0.663
MOD_NEK2_1	773	778	PF00069	0.612
MOD_NEK2_2	27	32	PF00069	0.664
MOD_NEK2_2	929	934	PF00069	0.499
MOD_PIKK_1	101	107	PF00454	0.598
MOD_PIKK_1	158	164	PF00454	0.664
MOD_PIKK_1	283	289	PF00454	0.685
MOD_PIKK_1	345	351	PF00454	0.581
MOD_PIKK_1	513	519	PF00454	0.560
MOD_PIKK_1	537	543	PF00454	0.706
MOD_PIKK_1	553	559	PF00454	0.541
MOD_PIKK_1	77	83	PF00454	0.708
MOD_PIKK_1	874	880	PF00454	0.653
MOD_PIKK_1	94	100	PF00454	0.564
MOD_PIKK_1	942	948	PF00454	0.543
MOD_PK_1	879	885	PF00069	0.647
MOD_PKA_1	258	264	PF00069	0.572
MOD_PKA_1	673	679	PF00069	0.625
MOD_PKA_2	120	126	PF00069	0.647
MOD_PKA_2	241	247	PF00069	0.649
MOD_PKA_2	258	264	PF00069	0.564
MOD_PKA_2	325	331	PF00069	0.666
MOD_PKA_2	553	559	PF00069	0.674
MOD_PKA_2	643	649	PF00069	0.625
MOD_PKA_2	673	679	PF00069	0.679
MOD_PKA_2	737	743	PF00069	0.664
MOD_PKA_2	74	80	PF00069	0.666
MOD_PKA_2	85	91	PF00069	0.667
MOD_PKA_2	878	884	PF00069	0.650
MOD_PKA_2	99	105	PF00069	0.586
MOD_PKB_1	12	20	PF00069	0.690
MOD_PKB_1	73	81	PF00069	0.630
MOD_Plk_1	113	119	PF00069	0.668
MOD_Plk_1	252	258	PF00069	0.587
MOD_Plk_1	498	504	PF00069	0.554
MOD_Plk_1	583	589	PF00069	0.646
MOD_Plk_1	762	768	PF00069	0.567
MOD_Plk_2-3	762	768	PF00069	0.484
MOD_Plk_4	267	273	PF00069	0.553
MOD_Plk_4	27	33	PF00069	0.657
MOD_Plk_4	328	334	PF00069	0.577
MOD_Plk_4	450	456	PF00069	0.693
MOD_Plk_4	498	504	PF00069	0.554
MOD_Plk_4	604	610	PF00069	0.601
MOD_Plk_4	657	663	PF00069	0.784
MOD_Plk_4	792	798	PF00069	0.588
MOD_Plk_4	929	935	PF00069	0.500
MOD_ProDKin_1	104	110	PF00069	0.618
MOD_ProDKin_1	121	127	PF00069	0.574
MOD_ProDKin_1	133	139	PF00069	0.588
MOD_ProDKin_1	234	240	PF00069	0.687
MOD_ProDKin_1	245	251	PF00069	0.602
MOD_ProDKin_1	37	43	PF00069	0.638
MOD_ProDKin_1	413	419	PF00069	0.672
MOD_ProDKin_1	442	448	PF00069	0.629
MOD_ProDKin_1	457	463	PF00069	0.563
MOD_ProDKin_1	620	626	PF00069	0.644
MOD_ProDKin_1	633	639	PF00069	0.639
MOD_ProDKin_1	68	74	PF00069	0.690
MOD_ProDKin_1	776	782	PF00069	0.577
MOD_ProDKin_1	824	830	PF00069	0.674
TRG_ENDOCYTIC_2	484	487	PF00928	0.490
TRG_ENDOCYTIC_2	766	769	PF00928	0.547
TRG_ER_diArg_1	1006	1009	PF00400	0.532
TRG_ER_diArg_1	11	14	PF00400	0.706
TRG_ER_diArg_1	233	236	PF00400	0.601
TRG_ER_diArg_1	257	259	PF00400	0.610
TRG_ER_diArg_1	272	274	PF00400	0.590
TRG_ER_diArg_1	456	459	PF00400	0.681
TRG_ER_diArg_1	478	481	PF00400	0.518
TRG_ER_diArg_1	536	539	PF00400	0.632
TRG_ER_diArg_1	593	595	PF00400	0.614
TRG_ER_diArg_1	624	626	PF00400	0.680
TRG_ER_diArg_1	641	644	PF00400	0.553
TRG_ER_diArg_1	673	675	PF00400	0.617
TRG_ER_diArg_1	72	75	PF00400	0.631
TRG_ER_diArg_1	957	960	PF00400	0.563
TRG_ER_diArg_1	983	986	PF00400	0.558
TRG_NES_CRM1_1	471	485	PF08389	0.559
TRG_NES_CRM1_1	749	763	PF08389	0.502
TRG_NLS_MonoExtC_3	456	461	PF00514	0.575
TRG_Pf-PMV_PEXEL_1	1009	1014	PF00026	0.437
TRG_Pf-PMV_PEXEL_1	753	757	PF00026	0.691
TRG_Pf-PMV_PEXEL_1	948	952	PF00026	0.512
TRG_Pf-PMV_PEXEL_1	986	991	PF00026	0.548

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4I5M8	Leishmania infantum	99%	100%
Q4Q793	Leishmania major	80%	100%