GATA-type domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X3D6_LEIDO

TriTrypDb:

LdBPK_301830.1 , LdCL_300023600 , LDHU3_30.2540

Length:

822

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 5
NetGPI	no	yes: 0, no: 5

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X3D6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X3D6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	242	246	PF00656	0.611
CLV_C14_Caspase3-7	55	59	PF00656	0.691
CLV_C14_Caspase3-7	667	671	PF00656	0.779
CLV_C14_Caspase3-7	769	773	PF00656	0.713
CLV_NRD_NRD_1	397	399	PF00675	0.629
CLV_NRD_NRD_1	444	446	PF00675	0.858
CLV_NRD_NRD_1	448	450	PF00675	0.798
CLV_NRD_NRD_1	460	462	PF00675	0.593
CLV_NRD_NRD_1	575	577	PF00675	0.758
CLV_NRD_NRD_1	667	669	PF00675	0.809
CLV_NRD_NRD_1	718	720	PF00675	0.655
CLV_NRD_NRD_1	721	723	PF00675	0.632
CLV_NRD_NRD_1	725	727	PF00675	0.618
CLV_PCSK_FUR_1	445	449	PF00082	0.863
CLV_PCSK_FUR_1	719	723	PF00082	0.799
CLV_PCSK_KEX2_1	446	448	PF00082	0.864
CLV_PCSK_KEX2_1	460	462	PF00082	0.626
CLV_PCSK_KEX2_1	532	534	PF00082	0.759
CLV_PCSK_KEX2_1	575	577	PF00082	0.758
CLV_PCSK_KEX2_1	654	656	PF00082	0.860
CLV_PCSK_KEX2_1	718	720	PF00082	0.811
CLV_PCSK_KEX2_1	721	723	PF00082	0.738
CLV_PCSK_KEX2_1	724	726	PF00082	0.675
CLV_PCSK_PC1ET2_1	446	448	PF00082	0.864
CLV_PCSK_PC1ET2_1	532	534	PF00082	0.759
CLV_PCSK_PC1ET2_1	654	656	PF00082	0.860
CLV_PCSK_PC7_1	721	727	PF00082	0.685
CLV_PCSK_SKI1_1	344	348	PF00082	0.744
CLV_PCSK_SKI1_1	398	402	PF00082	0.634
CLV_PCSK_SKI1_1	449	453	PF00082	0.785
CLV_PCSK_SKI1_1	692	696	PF00082	0.716
DEG_ODPH_VHL_1	195	208	PF01847	0.682
DEG_SPOP_SBC_1	170	174	PF00917	0.708
DEG_SPOP_SBC_1	227	231	PF00917	0.768
DEG_SPOP_SBC_1	255	259	PF00917	0.510
DOC_CDC14_PxL_1	501	509	PF14671	0.691
DOC_CYCLIN_yCln2_LP_2	390	396	PF00134	0.806
DOC_MAPK_DCC_7	398	407	PF00069	0.723
DOC_MAPK_gen_1	260	268	PF00069	0.747
DOC_MAPK_HePTP_8	781	793	PF00069	0.665
DOC_MAPK_MEF2A_6	398	407	PF00069	0.734
DOC_MAPK_MEF2A_6	784	793	PF00069	0.673
DOC_PP2B_LxvP_1	156	159	PF13499	0.755
DOC_PP2B_LxvP_1	400	403	PF13499	0.785
DOC_PP2B_LxvP_1	537	540	PF13499	0.777
DOC_PP4_FxxP_1	380	383	PF00568	0.767
DOC_USP7_MATH_1	103	107	PF00917	0.771
DOC_USP7_MATH_1	109	113	PF00917	0.715
DOC_USP7_MATH_1	170	174	PF00917	0.800
DOC_USP7_MATH_1	179	183	PF00917	0.648
DOC_USP7_MATH_1	214	218	PF00917	0.672
DOC_USP7_MATH_1	293	297	PF00917	0.806
DOC_USP7_MATH_1	31	35	PF00917	0.681
DOC_USP7_MATH_1	403	407	PF00917	0.806
DOC_USP7_MATH_1	43	47	PF00917	0.635
DOC_USP7_MATH_1	478	482	PF00917	0.713
DOC_USP7_MATH_1	51	55	PF00917	0.586
DOC_USP7_MATH_1	514	518	PF00917	0.824
DOC_USP7_MATH_1	588	592	PF00917	0.626
DOC_USP7_MATH_1	597	601	PF00917	0.569
DOC_USP7_MATH_1	61	65	PF00917	0.552
DOC_USP7_MATH_1	618	622	PF00917	0.645
DOC_USP7_MATH_1	664	668	PF00917	0.787
DOC_USP7_MATH_1	688	692	PF00917	0.783
DOC_USP7_MATH_1	756	760	PF00917	0.708
DOC_USP7_UBL2_3	805	809	PF12436	0.815
DOC_WW_Pin1_4	14	19	PF00397	0.632
DOC_WW_Pin1_4	143	148	PF00397	0.755
DOC_WW_Pin1_4	159	164	PF00397	0.616
DOC_WW_Pin1_4	195	200	PF00397	0.733
DOC_WW_Pin1_4	220	225	PF00397	0.744
DOC_WW_Pin1_4	232	237	PF00397	0.674
DOC_WW_Pin1_4	266	271	PF00397	0.792
DOC_WW_Pin1_4	275	280	PF00397	0.709
DOC_WW_Pin1_4	284	289	PF00397	0.572
DOC_WW_Pin1_4	297	302	PF00397	0.652
DOC_WW_Pin1_4	308	313	PF00397	0.665
DOC_WW_Pin1_4	384	389	PF00397	0.789
DOC_WW_Pin1_4	607	612	PF00397	0.839
DOC_WW_Pin1_4	627	632	PF00397	0.511
DOC_WW_Pin1_4	638	643	PF00397	0.641
DOC_WW_Pin1_4	770	775	PF00397	0.701
DOC_WW_Pin1_4	798	803	PF00397	0.685
LIG_14-3-3_CanoR_1	165	175	PF00244	0.773
LIG_14-3-3_CanoR_1	241	249	PF00244	0.825
LIG_14-3-3_CanoR_1	289	297	PF00244	0.613
LIG_14-3-3_CanoR_1	626	633	PF00244	0.804
LIG_14-3-3_CanoR_1	724	730	PF00244	0.692
LIG_BIR_II_1	1	5	PF00653	0.741
LIG_BIR_III_2	799	803	PF00653	0.614
LIG_FHA_1	113	119	PF00498	0.673
LIG_FHA_1	124	130	PF00498	0.576
LIG_FHA_1	190	196	PF00498	0.832
LIG_FHA_1	245	251	PF00498	0.829
LIG_FHA_1	292	298	PF00498	0.745
LIG_FHA_1	384	390	PF00498	0.695
LIG_FHA_1	643	649	PF00498	0.859
LIG_FHA_1	799	805	PF00498	0.756
LIG_FHA_1	85	91	PF00498	0.744
LIG_FHA_2	240	246	PF00498	0.648
LIG_FHA_2	256	262	PF00498	0.712
LIG_FHA_2	309	315	PF00498	0.751
LIG_FHA_2	34	40	PF00498	0.816
LIG_FHA_2	55	61	PF00498	0.718
LIG_FHA_2	559	565	PF00498	0.721
LIG_FHA_2	585	591	PF00498	0.723
LIG_FHA_2	726	732	PF00498	0.694
LIG_GSK3_LRP6_1	611	616	PF00069	0.624
LIG_LIR_Apic_2	379	383	PF02991	0.767
LIG_LIR_Apic_2	95	101	PF02991	0.783
LIG_LIR_Gen_1	421	432	PF02991	0.714
LIG_LIR_Gen_1	801	810	PF02991	0.695
LIG_LIR_Nem_3	421	427	PF02991	0.751
LIG_LIR_Nem_3	801	806	PF02991	0.730
LIG_MYND_1	105	109	PF01753	0.833
LIG_NRBOX	75	81	PF00104	0.594
LIG_SH2_CRK	778	782	PF00017	0.546
LIG_SH2_NCK_1	511	515	PF00017	0.599
LIG_SH2_PTP2	803	806	PF00017	0.699
LIG_SH2_SRC	254	257	PF00017	0.650
LIG_SH2_SRC	511	514	PF00017	0.596
LIG_SH2_SRC	785	788	PF00017	0.669
LIG_SH2_STAP1	778	782	PF00017	0.643
LIG_SH2_STAT3	581	584	PF00017	0.839
LIG_SH2_STAT5	716	719	PF00017	0.809
LIG_SH2_STAT5	803	806	PF00017	0.706
LIG_SH3_1	750	756	PF00018	0.749
LIG_SH3_3	161	167	PF00018	0.762
LIG_SH3_3	196	202	PF00018	0.732
LIG_SH3_3	273	279	PF00018	0.820
LIG_SH3_3	314	320	PF00018	0.674
LIG_SH3_3	426	432	PF00018	0.782
LIG_SH3_3	456	462	PF00018	0.744
LIG_SH3_3	533	539	PF00018	0.801
LIG_SH3_3	605	611	PF00018	0.768
LIG_SH3_3	750	756	PF00018	0.749
LIG_SUMO_SIM_par_1	300	305	PF11976	0.609
LIG_SUMO_SIM_par_1	425	430	PF11976	0.676
LIG_TRAF2_1	259	262	PF00917	0.730
LIG_TRAF2_1	311	314	PF00917	0.744
LIG_TRAF2_1	472	475	PF00917	0.635
LIG_TRAF2_1	561	564	PF00917	0.718
LIG_TYR_ITIM	776	781	PF00017	0.613
LIG_TYR_ITSM	799	806	PF00017	0.680
LIG_WW_1	713	716	PF00397	0.813
LIG_WW_3	162	166	PF00397	0.663
MOD_CDC14_SPxK_1	162	165	PF00782	0.761
MOD_CDK_SPK_2	284	289	PF00069	0.621
MOD_CDK_SPxK_1	159	165	PF00069	0.771
MOD_CDK_SPxxK_3	275	282	PF00069	0.615
MOD_CDK_SPxxK_3	798	805	PF00069	0.693
MOD_CK1_1	112	118	PF00069	0.609
MOD_CK1_1	123	129	PF00069	0.571
MOD_CK1_1	16	22	PF00069	0.586
MOD_CK1_1	169	175	PF00069	0.823
MOD_CK1_1	177	183	PF00069	0.672
MOD_CK1_1	188	194	PF00069	0.548
MOD_CK1_1	198	204	PF00069	0.650
MOD_CK1_1	2	8	PF00069	0.749
MOD_CK1_1	229	235	PF00069	0.850
MOD_CK1_1	33	39	PF00069	0.569
MOD_CK1_1	358	364	PF00069	0.799
MOD_CK1_1	406	412	PF00069	0.764
MOD_CK1_1	46	52	PF00069	0.693
MOD_CK1_1	54	60	PF00069	0.680
MOD_CK1_1	591	597	PF00069	0.757
MOD_CK1_1	607	613	PF00069	0.813
MOD_CK1_1	798	804	PF00069	0.709
MOD_CK1_1	81	87	PF00069	0.765
MOD_CK1_1	9	15	PF00069	0.727
MOD_CK2_1	255	261	PF00069	0.809
MOD_CK2_1	307	313	PF00069	0.753
MOD_CK2_1	33	39	PF00069	0.809
MOD_CK2_1	520	526	PF00069	0.789
MOD_CK2_1	558	564	PF00069	0.719
MOD_CK2_1	599	605	PF00069	0.685
MOD_CK2_1	725	731	PF00069	0.687
MOD_CK2_1	763	769	PF00069	0.689
MOD_GlcNHglycan	11	14	PF01048	0.726
MOD_GlcNHglycan	168	171	PF01048	0.739
MOD_GlcNHglycan	22	25	PF01048	0.637
MOD_GlcNHglycan	231	234	PF01048	0.762
MOD_GlcNHglycan	291	294	PF01048	0.828
MOD_GlcNHglycan	297	300	PF01048	0.721
MOD_GlcNHglycan	33	36	PF01048	0.585
MOD_GlcNHglycan	45	48	PF01048	0.679
MOD_GlcNHglycan	482	485	PF01048	0.815
MOD_GlcNHglycan	487	490	PF01048	0.733
MOD_GlcNHglycan	49	52	PF01048	0.594
MOD_GlcNHglycan	516	519	PF01048	0.807
MOD_GlcNHglycan	522	525	PF01048	0.780
MOD_GlcNHglycan	601	604	PF01048	0.775
MOD_GlcNHglycan	62	66	PF01048	0.570
MOD_GSK3_1	1	8	PF00069	0.756
MOD_GSK3_1	123	130	PF00069	0.730
MOD_GSK3_1	165	172	PF00069	0.818
MOD_GSK3_1	174	181	PF00069	0.662
MOD_GSK3_1	185	192	PF00069	0.502
MOD_GSK3_1	227	234	PF00069	0.800
MOD_GSK3_1	235	242	PF00069	0.656
MOD_GSK3_1	289	296	PF00069	0.797
MOD_GSK3_1	300	307	PF00069	0.613
MOD_GSK3_1	39	46	PF00069	0.760
MOD_GSK3_1	47	54	PF00069	0.693
MOD_GSK3_1	503	510	PF00069	0.769
MOD_GSK3_1	554	561	PF00069	0.767
MOD_GSK3_1	584	591	PF00069	0.723
MOD_GSK3_1	607	614	PF00069	0.779
MOD_GSK3_1	636	643	PF00069	0.766
MOD_GSK3_1	660	667	PF00069	0.797
MOD_GSK3_1	720	727	PF00069	0.785
MOD_GSK3_1	78	85	PF00069	0.775
MOD_GSK3_1	9	16	PF00069	0.690
MOD_N-GLC_1	123	128	PF02516	0.632
MOD_N-GLC_1	635	640	PF02516	0.748
MOD_NEK2_1	1	6	PF00069	0.759
MOD_NEK2_1	228	233	PF00069	0.673
MOD_NEK2_1	304	309	PF00069	0.720
MOD_NEK2_1	347	352	PF00069	0.641
MOD_NEK2_1	357	362	PF00069	0.688
MOD_NEK2_1	38	43	PF00069	0.690
MOD_NEK2_1	491	496	PF00069	0.743
MOD_NEK2_1	507	512	PF00069	0.693
MOD_NEK2_1	556	561	PF00069	0.765
MOD_PIKK_1	179	185	PF00454	0.752
MOD_PIKK_1	235	241	PF00454	0.843
MOD_PIKK_1	558	564	PF00454	0.622
MOD_PK_1	604	610	PF00069	0.736
MOD_PKA_1	398	404	PF00069	0.632
MOD_PKA_1	668	674	PF00069	0.851
MOD_PKA_1	724	730	PF00069	0.672
MOD_PKA_2	240	246	PF00069	0.750
MOD_PKA_2	625	631	PF00069	0.806
MOD_PKA_2	720	726	PF00069	0.784
MOD_PKB_1	722	730	PF00069	0.774
MOD_Plk_1	244	250	PF00069	0.784
MOD_Plk_1	304	310	PF00069	0.748
MOD_Plk_1	347	353	PF00069	0.606
MOD_Plk_1	588	594	PF00069	0.625
MOD_Plk_1	604	610	PF00069	0.596
MOD_Plk_2-3	526	532	PF00069	0.636
MOD_Plk_4	136	142	PF00069	0.697
MOD_Plk_4	503	509	PF00069	0.730
MOD_Plk_4	682	688	PF00069	0.708
MOD_ProDKin_1	14	20	PF00069	0.629
MOD_ProDKin_1	143	149	PF00069	0.755
MOD_ProDKin_1	159	165	PF00069	0.620
MOD_ProDKin_1	195	201	PF00069	0.731
MOD_ProDKin_1	220	226	PF00069	0.746
MOD_ProDKin_1	232	238	PF00069	0.674
MOD_ProDKin_1	266	272	PF00069	0.790
MOD_ProDKin_1	275	281	PF00069	0.712
MOD_ProDKin_1	284	290	PF00069	0.571
MOD_ProDKin_1	297	303	PF00069	0.653
MOD_ProDKin_1	308	314	PF00069	0.663
MOD_ProDKin_1	384	390	PF00069	0.790
MOD_ProDKin_1	607	613	PF00069	0.838
MOD_ProDKin_1	627	633	PF00069	0.510
MOD_ProDKin_1	638	644	PF00069	0.639
MOD_ProDKin_1	770	776	PF00069	0.700
MOD_ProDKin_1	798	804	PF00069	0.689
MOD_SUMO_for_1	804	807	PF00179	0.787
MOD_SUMO_for_1	808	811	PF00179	0.745
MOD_SUMO_for_1	816	819	PF00179	0.654
MOD_SUMO_rev_2	310	318	PF00179	0.692
MOD_SUMO_rev_2	468	473	PF00179	0.797
MOD_SUMO_rev_2	526	534	PF00179	0.676
TRG_DiLeu_BaEn_4	261	267	PF01217	0.746
TRG_DiLeu_BaLyEn_6	385	390	PF01217	0.812
TRG_ENDOCYTIC_2	778	781	PF00928	0.650
TRG_ENDOCYTIC_2	803	806	PF00928	0.699
TRG_ER_diArg_1	445	448	PF00400	0.863
TRG_ER_diArg_1	459	461	PF00400	0.636
TRG_ER_diArg_1	574	576	PF00400	0.832
TRG_ER_diArg_1	718	721	PF00400	0.804
TRG_ER_diArg_1	722	725	PF00400	0.713
TRG_NLS_MonoCore_2	444	449	PF00514	0.862
TRG_NLS_MonoExtC_3	444	449	PF00514	0.862
TRG_NLS_MonoExtN_4	442	449	PF00514	0.859
TRG_Pf-PMV_PEXEL_1	480	485	PF00026	0.641
TRG_Pf-PMV_PEXEL_1	740	744	PF00026	0.725

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4H929	Leishmania braziliensis	54%	100%
A4I5L0	Leishmania infantum	100%	100%
E9B0V5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	79%	100%
Q4Q7B1	Leishmania major	87%	100%