S1/P1_Nuclease_putative/Pfam:PF02265

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Download

Protein:

Gene product:

S1/P1 Nuclease, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X3B6_LEIDO

TriTrypDb:

LdCL_300020500 , LDHU3_30.1990

Length:


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Could not find GO cellular_component term for this entry.

A0A3S7X3B6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X3B6

Biological processes
Term	Name	Level	Count
GO:0006139	nucleobase-containing compound metabolic process	3	2
GO:0006259	DNA metabolic process	4	2
GO:0006308	DNA catabolic process	5	2
GO:0006725	cellular aromatic compound metabolic process	3	2
GO:0006807	nitrogen compound metabolic process	2	2
GO:0008152	metabolic process	1	2
GO:0009056	catabolic process	2	2
GO:0009057	macromolecule catabolic process	4	2
GO:0009987	cellular process	1	2
GO:0019439	aromatic compound catabolic process	4	2
GO:0034641	cellular nitrogen compound metabolic process	3	2
GO:0034655	nucleobase-containing compound catabolic process	4	2
GO:0043170	macromolecule metabolic process	3	2
GO:0044237	cellular metabolic process	2	2
GO:0044238	primary metabolic process	2	2
GO:0044248	cellular catabolic process	3	2
GO:0044260	obsolete cellular macromolecule metabolic process	3	2
GO:0044265	obsolete cellular macromolecule catabolic process	4	2
GO:0044270	cellular nitrogen compound catabolic process	4	2
GO:0046483	heterocycle metabolic process	3	2
GO:0046700	heterocycle catabolic process	4	2
GO:0071704	organic substance metabolic process	2	2
GO:0090304	nucleic acid metabolic process	4	2
GO:1901360	organic cyclic compound metabolic process	3	2
GO:1901361	organic cyclic compound catabolic process	4	2
GO:1901575	organic substance catabolic process	3	2

Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	2
GO:0003824	catalytic activity	1	2
GO:0004518	nuclease activity	4	2
GO:0004519	endonuclease activity	5	2
GO:0005488	binding	1	2
GO:0016787	hydrolase activity	2	2
GO:0016788	hydrolase activity, acting on ester bonds	3	2
GO:0043167	ion binding	2	2
GO:0043169	cation binding	3	2
GO:0046872	metal ion binding	4	2
GO:0097159	organic cyclic compound binding	2	2
GO:1901363	heterocyclic compound binding	2	2


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_FUR_1	24	28	PF00082	0.400
CLV_PCSK_FUR_1	65	69	PF00082	0.389
CLV_PCSK_KEX2_1	26	28	PF00082	0.400
CLV_PCSK_KEX2_1	67	69	PF00082	0.405
CLV_PCSK_PC1ET2_1	26	28	PF00082	0.400
CLV_PCSK_PC1ET2_1	67	69	PF00082	0.405
DEG_Nend_Nbox_1	1	3	PF02207	0.199
DEG_SCF_FBW7_1	9	16	PF00400	0.199
DOC_WW_Pin1_4	9	14	PF00397	0.199
LIG_14-3-3_CanoR_1	32	36	PF00244	0.199
LIG_eIF4E_1	38	44	PF01652	0.199
LIG_FHA_2	14	20	PF00498	0.199
LIG_LIR_Nem_3	6	11	PF02991	0.199
LIG_LYPXL_yS_3	8	11	PF13949	0.199
LIG_NRBOX	39	45	PF00104	0.199
LIG_SH2_STAT5	21	24	PF00017	0.199
LIG_SH2_STAT5	42	45	PF00017	0.199
LIG_TYR_ITSM	4	11	PF00017	0.199
MOD_CK2_1	13	19	PF00069	0.199
MOD_GSK3_1	43	50	PF00069	0.199
MOD_GSK3_1	9	16	PF00069	0.199
MOD_N-GLC_1	4	9	PF02516	0.400
MOD_NEK2_1	43	48	PF00069	0.199
MOD_PKA_2	31	37	PF00069	0.199
MOD_Plk_1	4	10	PF00069	0.199
MOD_Plk_1	54	60	PF00069	0.322
MOD_Plk_2-3	54	60	PF00069	0.322
MOD_Plk_4	43	49	PF00069	0.199
MOD_ProDKin_1	9	15	PF00069	0.199
TRG_ENDOCYTIC_2	8	11	PF00928	0.199