PSP1 C-terminal conserved region containing protein, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

PSP1 C-terminal conserved region, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X3A5_LEIDO

TriTrypDb:

LdBPK_301430.1 , LdCL_300019500 , LDHU3_30.1810

Length:

911

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X3A5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X3A5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	212	216	PF00656	0.644
CLV_C14_Caspase3-7	717	721	PF00656	0.674
CLV_NRD_NRD_1	235	237	PF00675	0.834
CLV_NRD_NRD_1	327	329	PF00675	0.698
CLV_NRD_NRD_1	504	506	PF00675	0.726
CLV_NRD_NRD_1	525	527	PF00675	0.596
CLV_NRD_NRD_1	584	586	PF00675	0.720
CLV_NRD_NRD_1	651	653	PF00675	0.753
CLV_NRD_NRD_1	801	803	PF00675	0.543
CLV_NRD_NRD_1	812	814	PF00675	0.401
CLV_PCSK_KEX2_1	234	236	PF00082	0.840
CLV_PCSK_KEX2_1	327	329	PF00082	0.698
CLV_PCSK_KEX2_1	504	506	PF00082	0.726
CLV_PCSK_KEX2_1	525	527	PF00082	0.596
CLV_PCSK_KEX2_1	584	586	PF00082	0.720
CLV_PCSK_KEX2_1	651	653	PF00082	0.753
CLV_PCSK_KEX2_1	730	732	PF00082	0.792
CLV_PCSK_KEX2_1	898	900	PF00082	0.571
CLV_PCSK_PC1ET2_1	730	732	PF00082	0.792
CLV_PCSK_PC1ET2_1	898	900	PF00082	0.571
CLV_PCSK_PC7_1	894	900	PF00082	0.450
CLV_PCSK_SKI1_1	705	709	PF00082	0.751
CLV_PCSK_SKI1_1	744	748	PF00082	0.687
CLV_PCSK_SKI1_1	818	822	PF00082	0.464
CLV_PCSK_SKI1_1	832	836	PF00082	0.340
CLV_PCSK_SKI1_1	885	889	PF00082	0.448
CLV_PCSK_SKI1_1	894	898	PF00082	0.373
CLV_Separin_Metazoa	208	212	PF03568	0.632
DEG_APCC_DBOX_1	743	751	PF00400	0.665
DEG_SCF_FBW7_1	194	199	PF00400	0.667
DEG_SCF_FBW7_1	781	787	PF00400	0.612
DEG_SPOP_SBC_1	433	437	PF00917	0.782
DEG_SPOP_SBC_1	627	631	PF00917	0.686
DOC_CKS1_1	128	133	PF01111	0.795
DOC_CKS1_1	155	160	PF01111	0.738
DOC_CKS1_1	309	314	PF01111	0.822
DOC_CKS1_1	58	63	PF01111	0.770
DOC_CKS1_1	781	786	PF01111	0.604
DOC_CYCLIN_RxL_1	741	751	PF00134	0.730
DOC_CYCLIN_RxL_1	813	825	PF00134	0.394
DOC_CYCLIN_yCln2_LP_2	259	262	PF00134	0.731
DOC_CYCLIN_yCln2_LP_2	89	95	PF00134	0.800
DOC_MAPK_gen_1	584	594	PF00069	0.723
DOC_MAPK_gen_1	802	808	PF00069	0.450
DOC_MAPK_gen_1	813	821	PF00069	0.504
DOC_MAPK_gen_1	832	841	PF00069	0.288
DOC_PP1_RVXF_1	883	890	PF00149	0.411
DOC_PP2B_LxvP_1	259	262	PF13499	0.731
DOC_PP2B_LxvP_1	293	296	PF13499	0.654
DOC_PP2B_LxvP_1	543	546	PF13499	0.758
DOC_PP2B_LxvP_1	93	96	PF13499	0.703
DOC_PP4_FxxP_1	176	179	PF00568	0.733
DOC_PP4_FxxP_1	58	61	PF00568	0.624
DOC_USP7_MATH_1	122	126	PF00917	0.735
DOC_USP7_MATH_1	134	138	PF00917	0.604
DOC_USP7_MATH_1	146	150	PF00917	0.690
DOC_USP7_MATH_1	220	224	PF00917	0.758
DOC_USP7_MATH_1	230	234	PF00917	0.649
DOC_USP7_MATH_1	255	259	PF00917	0.624
DOC_USP7_MATH_1	341	345	PF00917	0.732
DOC_USP7_MATH_1	375	379	PF00917	0.718
DOC_USP7_MATH_1	380	384	PF00917	0.710
DOC_USP7_MATH_1	39	43	PF00917	0.807
DOC_USP7_MATH_1	47	51	PF00917	0.624
DOC_USP7_MATH_1	515	519	PF00917	0.629
DOC_USP7_MATH_1	556	560	PF00917	0.769
DOC_USP7_MATH_1	627	631	PF00917	0.741
DOC_USP7_MATH_1	784	788	PF00917	0.578
DOC_USP7_MATH_1	865	869	PF00917	0.472
DOC_USP7_MATH_1	878	882	PF00917	0.338
DOC_USP7_MATH_2	18	24	PF00917	0.618
DOC_USP7_MATH_2	766	772	PF00917	0.616
DOC_WW_Pin1_4	127	132	PF00397	0.711
DOC_WW_Pin1_4	154	159	PF00397	0.684
DOC_WW_Pin1_4	175	180	PF00397	0.697
DOC_WW_Pin1_4	192	197	PF00397	0.684
DOC_WW_Pin1_4	215	220	PF00397	0.611
DOC_WW_Pin1_4	226	231	PF00397	0.669
DOC_WW_Pin1_4	27	32	PF00397	0.823
DOC_WW_Pin1_4	286	291	PF00397	0.703
DOC_WW_Pin1_4	308	313	PF00397	0.722
DOC_WW_Pin1_4	567	572	PF00397	0.686
DOC_WW_Pin1_4	57	62	PF00397	0.720
DOC_WW_Pin1_4	69	74	PF00397	0.758
DOC_WW_Pin1_4	762	767	PF00397	0.548
DOC_WW_Pin1_4	780	785	PF00397	0.413
DOC_WW_Pin1_4	88	93	PF00397	0.553
LIG_14-3-3_CanoR_1	292	296	PF00244	0.817
LIG_14-3-3_CanoR_1	316	322	PF00244	0.823
LIG_14-3-3_CanoR_1	434	442	PF00244	0.784
LIG_14-3-3_CanoR_1	445	452	PF00244	0.827
LIG_14-3-3_CanoR_1	56	61	PF00244	0.789
LIG_14-3-3_CanoR_1	613	618	PF00244	0.827
LIG_14-3-3_CanoR_1	662	670	PF00244	0.757
LIG_14-3-3_CanoR_1	85	89	PF00244	0.738
LIG_14-3-3_CanoR_1	876	884	PF00244	0.492
LIG_Actin_WH2_2	789	804	PF00022	0.668
LIG_BIR_III_4	224	228	PF00653	0.668
LIG_BRCT_BRCA1_1	443	447	PF00533	0.707
LIG_FHA_1	106	112	PF00498	0.798
LIG_FHA_1	155	161	PF00498	0.592
LIG_FHA_1	197	203	PF00498	0.667
LIG_FHA_1	334	340	PF00498	0.695
LIG_FHA_1	736	742	PF00498	0.761
LIG_FHA_1	823	829	PF00498	0.433
LIG_FHA_2	157	163	PF00498	0.695
LIG_FHA_2	227	233	PF00498	0.625
LIG_FHA_2	481	487	PF00498	0.508
LIG_FHA_2	632	638	PF00498	0.741
LIG_FHA_2	70	76	PF00498	0.674
LIG_FHA_2	715	721	PF00498	0.716
LIG_LIR_Apic_2	173	179	PF02991	0.734
LIG_LIR_Gen_1	629	640	PF02991	0.635
LIG_LIR_Gen_1	771	779	PF02991	0.582
LIG_LIR_Gen_1	786	796	PF02991	0.523
LIG_LIR_Gen_1	844	854	PF02991	0.446
LIG_LIR_Nem_3	195	200	PF02991	0.736
LIG_LIR_Nem_3	629	635	PF02991	0.637
LIG_LIR_Nem_3	771	775	PF02991	0.591
LIG_LIR_Nem_3	786	792	PF02991	0.526
LIG_LIR_Nem_3	844	850	PF02991	0.377
LIG_PCNA_yPIPBox_3	203	211	PF02747	0.642
LIG_Pex14_2	168	172	PF04695	0.790
LIG_PTB_Apo_2	166	173	PF02174	0.675
LIG_Rb_LxCxE_1	743	765	PF01857	0.625
LIG_SH2_CRK	632	636	PF00017	0.634
LIG_SH2_CRK	789	793	PF00017	0.641
LIG_SH2_CRK	859	863	PF00017	0.411
LIG_SH2_NCK_1	467	471	PF00017	0.793
LIG_SH2_NCK_1	482	486	PF00017	0.617
LIG_SH2_NCK_1	772	776	PF00017	0.674
LIG_SH2_SRC	761	764	PF00017	0.647
LIG_SH2_SRC	772	775	PF00017	0.560
LIG_SH2_SRC	94	97	PF00017	0.743
LIG_SH2_STAP1	200	204	PF00017	0.691
LIG_SH2_STAP1	467	471	PF00017	0.839
LIG_SH2_STAP1	789	793	PF00017	0.703
LIG_SH2_STAT3	200	203	PF00017	0.757
LIG_SH2_STAT5	333	336	PF00017	0.704
LIG_SH2_STAT5	482	485	PF00017	0.511
LIG_SH2_STAT5	756	759	PF00017	0.520
LIG_SH2_STAT5	827	830	PF00017	0.411
LIG_SH2_STAT5	847	850	PF00017	0.183
LIG_SH3_2	608	613	PF14604	0.753
LIG_SH3_3	272	278	PF00018	0.788
LIG_SH3_3	414	420	PF00018	0.773
LIG_SH3_3	575	581	PF00018	0.734
LIG_SH3_3	591	597	PF00018	0.710
LIG_SH3_3	605	611	PF00018	0.766
LIG_SUMO_SIM_anti_2	691	697	PF11976	0.625
LIG_SUMO_SIM_par_1	533	540	PF11976	0.766
LIG_SUMO_SIM_par_1	590	595	PF11976	0.663
LIG_SUMO_SIM_par_1	671	677	PF11976	0.752
LIG_SUMO_SIM_par_1	860	866	PF11976	0.306
LIG_TRAF2_1	205	208	PF00917	0.623
LIG_TYR_ITIM	770	775	PF00017	0.575
LIG_TYR_ITIM	857	862	PF00017	0.411
LIG_WRC_WIRS_1	214	219	PF05994	0.723
LIG_WRC_WIRS_1	847	852	PF05994	0.411
LIG_WW_1	464	467	PF00397	0.719
MOD_CDK_SPxK_1	127	133	PF00069	0.653
MOD_CDK_SPxK_1	215	221	PF00069	0.674
MOD_CDK_SPxK_1	286	292	PF00069	0.706
MOD_CDK_SPxxK_3	57	64	PF00069	0.626
MOD_CK1_1	123	129	PF00069	0.744
MOD_CK1_1	171	177	PF00069	0.699
MOD_CK1_1	19	25	PF00069	0.717
MOD_CK1_1	223	229	PF00069	0.707
MOD_CK1_1	361	367	PF00069	0.698
MOD_CK1_1	42	48	PF00069	0.749
MOD_CK1_1	432	438	PF00069	0.846
MOD_CK1_1	488	494	PF00069	0.797
MOD_CK1_1	544	550	PF00069	0.711
MOD_CK1_1	567	573	PF00069	0.721
MOD_CK1_1	63	69	PF00069	0.842
MOD_CK1_1	631	637	PF00069	0.748
MOD_CK1_1	729	735	PF00069	0.686
MOD_CK1_1	868	874	PF00069	0.450
MOD_CK2_1	171	177	PF00069	0.687
MOD_CK2_1	226	232	PF00069	0.625
MOD_CK2_1	300	306	PF00069	0.712
MOD_CK2_1	385	391	PF00069	0.804
MOD_CK2_1	631	637	PF00069	0.736
MOD_CK2_1	64	70	PF00069	0.815
MOD_CK2_1	762	768	PF00069	0.681
MOD_Cter_Amidation	523	526	PF01082	0.631
MOD_GlcNHglycan	107	111	PF01048	0.756
MOD_GlcNHglycan	116	119	PF01048	0.781
MOD_GlcNHglycan	136	139	PF01048	0.567
MOD_GlcNHglycan	148	151	PF01048	0.773
MOD_GlcNHglycan	173	176	PF01048	0.699
MOD_GlcNHglycan	224	228	PF01048	0.756
MOD_GlcNHglycan	262	265	PF01048	0.647
MOD_GlcNHglycan	322	325	PF01048	0.625
MOD_GlcNHglycan	365	368	PF01048	0.695
MOD_GlcNHglycan	387	390	PF01048	0.704
MOD_GlcNHglycan	431	434	PF01048	0.774
MOD_GlcNHglycan	44	47	PF01048	0.854
MOD_GlcNHglycan	488	491	PF01048	0.700
MOD_GlcNHglycan	543	546	PF01048	0.661
MOD_GlcNHglycan	572	575	PF01048	0.758
MOD_GlcNHglycan	615	618	PF01048	0.815
MOD_GlcNHglycan	648	651	PF01048	0.654
MOD_GlcNHglycan	65	69	PF01048	0.738
MOD_GlcNHglycan	664	667	PF01048	0.670
MOD_GlcNHglycan	676	679	PF01048	0.647
MOD_GlcNHglycan	8	11	PF01048	0.824
MOD_GlcNHglycan	836	839	PF01048	0.460
MOD_GSK3_1	116	123	PF00069	0.778
MOD_GSK3_1	142	149	PF00069	0.737
MOD_GSK3_1	150	157	PF00069	0.670
MOD_GSK3_1	16	23	PF00069	0.771
MOD_GSK3_1	171	178	PF00069	0.809
MOD_GSK3_1	192	199	PF00069	0.677
MOD_GSK3_1	209	216	PF00069	0.499
MOD_GSK3_1	226	233	PF00069	0.674
MOD_GSK3_1	307	314	PF00069	0.695
MOD_GSK3_1	333	340	PF00069	0.616
MOD_GSK3_1	381	388	PF00069	0.686
MOD_GSK3_1	425	432	PF00069	0.831
MOD_GSK3_1	441	448	PF00069	0.581
MOD_GSK3_1	485	492	PF00069	0.773
MOD_GSK3_1	541	548	PF00069	0.755
MOD_GSK3_1	552	559	PF00069	0.705
MOD_GSK3_1	56	63	PF00069	0.832
MOD_GSK3_1	627	634	PF00069	0.673
MOD_GSK3_1	725	732	PF00069	0.716
MOD_GSK3_1	736	743	PF00069	0.606
MOD_GSK3_1	780	787	PF00069	0.571
MOD_GSK3_1	84	91	PF00069	0.750
MOD_GSK3_1	842	849	PF00069	0.364
MOD_GSK3_1	867	874	PF00069	0.450
MOD_GSK3_1	901	908	PF00069	0.685
MOD_LATS_1	62	68	PF00433	0.634
MOD_N-GLC_1	114	119	PF02516	0.839
MOD_N-GLC_1	168	173	PF02516	0.676
MOD_N-GLC_1	342	347	PF02516	0.641
MOD_N-GLC_1	42	47	PF02516	0.815
MOD_N-GLC_1	708	713	PF02516	0.654
MOD_N-GLC_2	396	398	PF02516	0.570
MOD_NEK2_1	25	30	PF00069	0.846
MOD_NEK2_1	726	731	PF00069	0.726
MOD_NEK2_1	740	745	PF00069	0.641
MOD_NEK2_1	821	826	PF00069	0.369
MOD_NEK2_1	834	839	PF00069	0.328
MOD_NEK2_1	850	855	PF00069	0.393
MOD_NEK2_1	901	906	PF00069	0.674
MOD_NEK2_2	784	789	PF00069	0.631
MOD_PIKK_1	116	122	PF00454	0.728
MOD_PIKK_1	48	54	PF00454	0.831
MOD_PIKK_1	564	570	PF00454	0.763
MOD_PIKK_1	656	662	PF00454	0.803
MOD_PIKK_1	905	911	PF00454	0.725
MOD_PKA_1	730	736	PF00069	0.801
MOD_PKA_2	239	245	PF00069	0.644
MOD_PKA_2	291	297	PF00069	0.821
MOD_PKA_2	315	321	PF00069	0.826
MOD_PKA_2	433	439	PF00069	0.770
MOD_PKA_2	48	54	PF00069	0.831
MOD_PKA_2	661	667	PF00069	0.762
MOD_PKA_2	730	736	PF00069	0.801
MOD_PKA_2	84	90	PF00069	0.740
MOD_PKB_1	54	62	PF00069	0.787
MOD_Plk_1	168	174	PF00069	0.705
MOD_Plk_1	19	25	PF00069	0.688
MOD_Plk_2-3	156	162	PF00069	0.591
MOD_Plk_2-3	768	774	PF00069	0.636
MOD_Plk_4	123	129	PF00069	0.799
MOD_Plk_4	156	162	PF00069	0.591
MOD_Plk_4	20	26	PF00069	0.653
MOD_Plk_4	255	261	PF00069	0.629
MOD_Plk_4	403	409	PF00069	0.610
MOD_Plk_4	515	521	PF00069	0.650
MOD_Plk_4	736	742	PF00069	0.723
MOD_Plk_4	784	790	PF00069	0.637
MOD_Plk_4	84	90	PF00069	0.667
MOD_Plk_4	842	848	PF00069	0.411
MOD_ProDKin_1	127	133	PF00069	0.710
MOD_ProDKin_1	154	160	PF00069	0.685
MOD_ProDKin_1	175	181	PF00069	0.698
MOD_ProDKin_1	192	198	PF00069	0.683
MOD_ProDKin_1	215	221	PF00069	0.615
MOD_ProDKin_1	226	232	PF00069	0.671
MOD_ProDKin_1	27	33	PF00069	0.823
MOD_ProDKin_1	286	292	PF00069	0.706
MOD_ProDKin_1	308	314	PF00069	0.721
MOD_ProDKin_1	567	573	PF00069	0.686
MOD_ProDKin_1	57	63	PF00069	0.721
MOD_ProDKin_1	69	75	PF00069	0.759
MOD_ProDKin_1	762	768	PF00069	0.557
MOD_ProDKin_1	780	786	PF00069	0.412
MOD_ProDKin_1	88	94	PF00069	0.555
MOD_SUMO_rev_2	881	889	PF00179	0.450
TRG_DiLeu_BaEn_1	20	25	PF01217	0.775
TRG_DiLeu_BaLyEn_6	742	747	PF01217	0.537
TRG_DiLeu_BaLyEn_6	857	862	PF01217	0.450
TRG_ENDOCYTIC_2	253	256	PF00928	0.682
TRG_ENDOCYTIC_2	632	635	PF00928	0.635
TRG_ENDOCYTIC_2	772	775	PF00928	0.583
TRG_ENDOCYTIC_2	789	792	PF00928	0.506
TRG_ENDOCYTIC_2	847	850	PF00928	0.411
TRG_ENDOCYTIC_2	859	862	PF00928	0.411
TRG_ER_diArg_1	152	155	PF00400	0.755
TRG_ER_diArg_1	234	236	PF00400	0.779
TRG_ER_diArg_1	326	328	PF00400	0.701
TRG_ER_diArg_1	525	527	PF00400	0.596
TRG_ER_diArg_1	583	585	PF00400	0.726
TRG_ER_diArg_1	651	653	PF00400	0.753
TRG_ER_diArg_1	77	80	PF00400	0.824
TRG_Pf-PMV_PEXEL_1	818	822	PF00026	0.400

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IA65	Leptomonas seymouri	45%	91%
A4HI89	Leishmania braziliensis	68%	97%
A4I5G8	Leishmania infantum	99%	100%
E9B0R6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	99%
Q4Q7G7	Leishmania major	90%	99%