DUF5063 domain-containing protein

Quick info Annotations Localization Phosphorylation Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X371_LEIDO

TriTrypDb:

LdBPK_300820.1 , LdCL_300013300 , LDHU3_30.1030

Length:

124

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Show entries

Cellular components
Term	Name	Level	Count
GO:0005654	nucleoplasm	2	1
GO:0005815	microtubule organizing center	2	1
GO:0005930	axoneme	2	1
GO:0036064	ciliary basal body	3	1
GO:0110165	cellular anatomical entity	1	1

Previous1Next

Phosphorylation

Amastigote: 118, 122

Expansion

Sequence features

A0A3S7X371

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X371

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_PCSK_KEX2_1	110	112	PF00082	0.361
CLV_PCSK_KEX2_1	70	72	PF00082	0.539
CLV_PCSK_PC1ET2_1	110	112	PF00082	0.361
CLV_PCSK_PC1ET2_1	70	72	PF00082	0.533
CLV_PCSK_SKI1_1	34	38	PF00082	0.477
CLV_PCSK_SKI1_1	50	54	PF00082	0.248
CLV_Separin_Metazoa	93	97	PF03568	0.337
DEG_MDM2_SWIB_1	86	94	PF02201	0.321
DEG_Nend_UBRbox_3	1	3	PF02207	0.587
DOC_PP1_RVXF_1	22	29	PF00149	0.308

Previous1 2 3Next

Homologs

Show entries


Protein	Taxonomy	Sequence identity	Coverage
A0A0S4JBX9	Bodo saltans	52%	100%
A0A1X0P2S3	Trypanosomatidae	50%	100%
A0A3R7MCC7	Trypanosoma rangeli	46%	81%
A4HI32	Leishmania braziliensis	61%	100%
A4I5A8	Leishmania infantum	100%	100%
C6K3W5	Leptomonas seymouri	64%	100%
C9ZQP2	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	47%	96%
E9B0K4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	81%	100%
Q4Q7M8	Leishmania major	87%	100%

Previous1Next