Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X318_LEIDO

TriTrypDb:

LdBPK_300530.1 , LdCL_300010400 , LDHU3_30.0710

Length:

1148

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 5

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Show entries

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0005929	cilium	4	7
GO:0042995	cell projection	2	7
GO:0043226	organelle	2	7
GO:0043227	membrane-bounded organelle	3	7
GO:0110165	cellular anatomical entity	1	7
GO:0120025	plasma membrane bounded cell projection	3	7

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Expansion

Sequence features

A0A3S7X318

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X318

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1117	1121	PF00656	0.573
CLV_C14_Caspase3-7	192	196	PF00656	0.578
CLV_C14_Caspase3-7	438	442	PF00656	0.445
CLV_C14_Caspase3-7	455	459	PF00656	0.339
CLV_C14_Caspase3-7	475	479	PF00656	0.472
CLV_C14_Caspase3-7	700	704	PF00656	0.617
CLV_NRD_NRD_1	1021	1023	PF00675	0.633
CLV_NRD_NRD_1	1135	1137	PF00675	0.684
CLV_NRD_NRD_1	316	318	PF00675	0.384
CLV_NRD_NRD_1	498	500	PF00675	0.594

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PEG7	Leptomonas seymouri	35%	94%
A4HI02	Leishmania braziliensis	69%	99%
A4I579	Leishmania infantum	99%	100%
E9B0H6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	87%	99%
Q4Q7Q5	Leishmania major	91%	100%

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