LeishMANIAdb
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Putative integral membrane protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Putative integral membrane protein
Gene product:
hypothetical protein
Species:
Leishmania donovani
UniProt:
A0A3S7X2Y7_LEIDO
TriTrypDb:
LdCL_300005000 , LDHU3_30.0020
Length:
136

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 5
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 3, no: 0
NetGPI no yes: 0, no: 3
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X2Y7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X2Y7

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_PCSK_KEX2_1 108 110 PF00082 0.586
CLV_PCSK_PC1ET2_1 108 110 PF00082 0.586
CLV_PCSK_SKI1_1 101 105 PF00082 0.609
CLV_PCSK_SKI1_1 4 8 PF00082 0.592
DEG_SCF_FBW7_1 65 71 PF00400 0.341
DOC_CKS1_1 65 70 PF01111 0.342
DOC_CYCLIN_RxL_1 1 10 PF00134 0.399
DOC_MAPK_MEF2A_6 4 13 PF00069 0.386
DOC_MAPK_NFAT4_5 4 12 PF00069 0.385
DOC_USP7_MATH_1 121 125 PF00917 0.300
DOC_USP7_MATH_1 58 62 PF00917 0.346
DOC_USP7_MATH_1 74 78 PF00917 0.341
DOC_USP7_UBL2_3 104 108 PF12436 0.369
DOC_WW_Pin1_4 26 31 PF00397 0.414
DOC_WW_Pin1_4 64 69 PF00397 0.376
DOC_WW_Pin1_4 70 75 PF00397 0.350
LIG_14-3-3_CanoR_1 109 117 PF00244 0.466
LIG_BIR_II_1 1 5 PF00653 0.538
LIG_FHA_1 8 14 PF00498 0.399
LIG_LIR_Nem_3 59 65 PF02991 0.337
LIG_NRBOX 8 14 PF00104 0.506
LIG_SH2_CRK 28 32 PF00017 0.386
LIG_SH2_NCK_1 28 32 PF00017 0.405
LIG_SH2_STAT5 28 31 PF00017 0.402
LIG_SH2_STAT5 64 67 PF00017 0.358
LIG_SH2_STAT5 99 102 PF00017 0.346
LIG_SUMO_SIM_par_1 5 10 PF11976 0.391
LIG_TRAF2_1 91 94 PF00917 0.329
LIG_TRFH_1 64 68 PF08558 0.340
MOD_CDK_SPxK_1 64 70 PF00069 0.341
MOD_CK1_1 110 116 PF00069 0.457
MOD_CK1_1 20 26 PF00069 0.526
MOD_CK1_1 56 62 PF00069 0.308
MOD_GlcNHglycan 109 112 PF01048 0.669
MOD_GlcNHglycan 19 22 PF01048 0.649
MOD_GlcNHglycan 86 89 PF01048 0.666
MOD_GSK3_1 112 119 PF00069 0.450
MOD_GSK3_1 49 56 PF00069 0.386
MOD_GSK3_1 64 71 PF00069 0.348
MOD_GSK3_1 80 87 PF00069 0.363
MOD_N-GLC_2 90 92 PF02516 0.531
MOD_NEK2_1 127 132 PF00069 0.253
MOD_NEK2_1 17 22 PF00069 0.501
MOD_NEK2_1 7 12 PF00069 0.544
MOD_Plk_4 122 128 PF00069 0.284
MOD_Plk_4 7 13 PF00069 0.421
MOD_ProDKin_1 26 32 PF00069 0.417
MOD_ProDKin_1 64 70 PF00069 0.375
TRG_ENDOCYTIC_2 28 31 PF00928 0.383

Homologs

Protein Taxonomy Sequence identity Coverage
A4H446 Leishmania braziliensis 34% 69%
E9AK02 Leishmania mexicana (strain MHOM/GT/2001/U1103) 37% 75%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS