LeishMANIAdb
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Helicase, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Helicase, putative
Gene product:
helicase, putative
Species:
Leishmania donovani
UniProt:
A0A3S7X2X3_LEIDO
TriTrypDb:
LdBPK_292770.1 * , LdCL_290033800 , LDHU3_29.4080
Length:
953

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0005634 nucleus 5 11
GO:0043226 organelle 2 11
GO:0043227 membrane-bounded organelle 3 11
GO:0043229 intracellular organelle 3 11
GO:0043231 intracellular membrane-bounded organelle 4 11
GO:0110165 cellular anatomical entity 1 11

Expansion

Sequence features

A0A3S7X2X3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X2X3

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 12
GO:0006725 cellular aromatic compound metabolic process 3 12
GO:0006807 nitrogen compound metabolic process 2 12
GO:0008152 metabolic process 1 12
GO:0009987 cellular process 1 12
GO:0034641 cellular nitrogen compound metabolic process 3 12
GO:0044237 cellular metabolic process 2 12
GO:0044238 primary metabolic process 2 12
GO:0046483 heterocycle metabolic process 3 12
GO:0071704 organic substance metabolic process 2 12
GO:1901360 organic cyclic compound metabolic process 3 12
GO:0000018 regulation of DNA recombination 6 1
GO:0000723 telomere maintenance 5 1
GO:0006259 DNA metabolic process 4 1
GO:0006282 regulation of DNA repair 6 1
GO:0006996 organelle organization 4 1
GO:0009892 negative regulation of metabolic process 4 1
GO:0010569 regulation of double-strand break repair via homologous recombination 7 1
GO:0010605 negative regulation of macromolecule metabolic process 5 1
GO:0016043 cellular component organization 3 1
GO:0019219 regulation of nucleobase-containing compound metabolic process 5 1
GO:0019222 regulation of metabolic process 3 1
GO:0031323 regulation of cellular metabolic process 4 1
GO:0031324 negative regulation of cellular metabolic process 5 1
GO:0032200 telomere organization 6 1
GO:0032204 regulation of telomere maintenance 6 1
GO:0032392 DNA geometric change 7 1
GO:0032508 DNA duplex unwinding 8 1
GO:0033043 regulation of organelle organization 5 1
GO:0033044 regulation of chromosome organization 6 1
GO:0043170 macromolecule metabolic process 3 1
GO:0044087 regulation of cellular component biogenesis 4 1
GO:0044260 obsolete cellular macromolecule metabolic process 3 1
GO:0045910 negative regulation of DNA recombination 7 1
GO:0045934 negative regulation of nucleobase-containing compound metabolic process 6 1
GO:0048519 negative regulation of biological process 3 1
GO:0048523 negative regulation of cellular process 4 1
GO:0048583 regulation of response to stimulus 3 1
GO:0050789 regulation of biological process 2 1
GO:0050794 regulation of cellular process 3 1
GO:0051052 regulation of DNA metabolic process 5 1
GO:0051053 negative regulation of DNA metabolic process 6 1
GO:0051128 regulation of cellular component organization 4 1
GO:0051129 negative regulation of cellular component organization 5 1
GO:0051171 regulation of nitrogen compound metabolic process 4 1
GO:0051172 negative regulation of nitrogen compound metabolic process 5 1
GO:0051276 chromosome organization 5 1
GO:0060255 regulation of macromolecule metabolic process 4 1
GO:0065007 biological regulation 1 1
GO:0071103 DNA conformation change 6 1
GO:0071840 cellular component organization or biogenesis 2 1
GO:0080090 regulation of primary metabolic process 4 1
GO:0080134 regulation of response to stress 4 1
GO:0080135 regulation of cellular response to stress 4 1
GO:0090304 nucleic acid metabolic process 4 1
GO:0090657 telomeric loop disassembly 6 1
GO:1904429 regulation of t-circle formation 5 1
GO:1904430 negative regulation of t-circle formation 6 1
GO:2000779 regulation of double-strand break repair 7 1
GO:2001020 obsolete regulation of response to DNA damage stimulus 5 1
GO:0006950 response to stress 2 3
GO:0006974 DNA damage response 4 3
GO:0033554 cellular response to stress 3 3
GO:0050896 response to stimulus 1 3
GO:0051716 cellular response to stimulus 2 3
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 12
GO:0003676 nucleic acid binding 3 12
GO:0003677 DNA binding 4 12
GO:0003678 DNA helicase activity 3 12
GO:0003824 catalytic activity 1 12
GO:0004386 helicase activity 2 12
GO:0005488 binding 1 12
GO:0005524 ATP binding 5 12
GO:0008094 ATP-dependent activity, acting on DNA 2 12
GO:0016787 hydrolase activity 2 12
GO:0016817 hydrolase activity, acting on acid anhydrides 3 12
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 12
GO:0017076 purine nucleotide binding 4 12
GO:0030554 adenyl nucleotide binding 5 12
GO:0032553 ribonucleotide binding 3 12
GO:0032555 purine ribonucleotide binding 4 12
GO:0032559 adenyl ribonucleotide binding 5 12
GO:0035639 purine ribonucleoside triphosphate binding 4 12
GO:0036094 small molecule binding 2 12
GO:0043167 ion binding 2 12
GO:0043168 anion binding 3 12
GO:0097159 organic cyclic compound binding 2 12
GO:0097367 carbohydrate derivative binding 2 12
GO:0140097 catalytic activity, acting on DNA 3 12
GO:0140640 catalytic activity, acting on a nucleic acid 2 12
GO:0140657 ATP-dependent activity 1 12
GO:1901265 nucleoside phosphate binding 3 12
GO:1901363 heterocyclic compound binding 2 12
GO:0005515 protein binding 2 1
GO:0019899 enzyme binding 3 1
GO:0070182 DNA polymerase binding 4 1
GO:0016462 pyrophosphatase activity 5 1
GO:0016887 ATP hydrolysis activity 7 1
GO:0017111 ribonucleoside triphosphate phosphatase activity 6 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 603 607 PF00656 0.486
CLV_MEL_PAP_1 498 504 PF00089 0.399
CLV_NRD_NRD_1 700 702 PF00675 0.426
CLV_NRD_NRD_1 722 724 PF00675 0.463
CLV_NRD_NRD_1 775 777 PF00675 0.535
CLV_PCSK_FUR_1 628 632 PF00082 0.220
CLV_PCSK_FUR_1 773 777 PF00082 0.622
CLV_PCSK_KEX2_1 106 108 PF00082 0.231
CLV_PCSK_KEX2_1 630 632 PF00082 0.220
CLV_PCSK_KEX2_1 700 702 PF00082 0.419
CLV_PCSK_KEX2_1 722 724 PF00082 0.439
CLV_PCSK_KEX2_1 773 775 PF00082 0.553
CLV_PCSK_PC1ET2_1 106 108 PF00082 0.214
CLV_PCSK_PC1ET2_1 630 632 PF00082 0.220
CLV_PCSK_SKI1_1 103 107 PF00082 0.204
CLV_PCSK_SKI1_1 129 133 PF00082 0.284
CLV_PCSK_SKI1_1 157 161 PF00082 0.178
CLV_PCSK_SKI1_1 295 299 PF00082 0.313
CLV_PCSK_SKI1_1 342 346 PF00082 0.380
CLV_PCSK_SKI1_1 364 368 PF00082 0.431
CLV_PCSK_SKI1_1 374 378 PF00082 0.423
CLV_PCSK_SKI1_1 401 405 PF00082 0.328
CLV_PCSK_SKI1_1 557 561 PF00082 0.220
CLV_PCSK_SKI1_1 610 614 PF00082 0.320
CLV_PCSK_SKI1_1 647 651 PF00082 0.241
CLV_PCSK_SKI1_1 781 785 PF00082 0.611
CLV_PCSK_SKI1_1 881 885 PF00082 0.423
CLV_PCSK_SKI1_1 891 895 PF00082 0.475
CLV_PCSK_SKI1_1 913 917 PF00082 0.472
DEG_SPOP_SBC_1 242 246 PF00917 0.484
DOC_CYCLIN_RxL_1 151 161 PF00134 0.378
DOC_CYCLIN_RxL_1 217 228 PF00134 0.431
DOC_CYCLIN_RxL_1 412 423 PF00134 0.455
DOC_CYCLIN_RxL_1 46 57 PF00134 0.322
DOC_CYCLIN_RxL_1 888 897 PF00134 0.456
DOC_MAPK_gen_1 426 435 PF00069 0.339
DOC_MAPK_gen_1 595 604 PF00069 0.433
DOC_MAPK_gen_1 672 681 PF00069 0.486
DOC_MAPK_MEF2A_6 326 335 PF00069 0.245
DOC_MAPK_MEF2A_6 426 435 PF00069 0.339
DOC_MAPK_MEF2A_6 586 593 PF00069 0.455
DOC_MAPK_NFAT4_5 586 594 PF00069 0.445
DOC_PP1_RVXF_1 413 420 PF00149 0.450
DOC_PP1_RVXF_1 545 551 PF00149 0.330
DOC_PP2B_LxvP_1 908 911 PF13499 0.506
DOC_PP4_FxxP_1 560 563 PF00568 0.420
DOC_USP7_MATH_1 142 146 PF00917 0.439
DOC_USP7_MATH_1 164 168 PF00917 0.504
DOC_USP7_MATH_1 375 379 PF00917 0.479
DOC_USP7_MATH_1 434 438 PF00917 0.444
DOC_USP7_MATH_1 563 567 PF00917 0.513
DOC_USP7_MATH_1 62 66 PF00917 0.572
DOC_USP7_MATH_1 783 787 PF00917 0.590
DOC_USP7_MATH_1 791 795 PF00917 0.646
DOC_USP7_MATH_1 805 809 PF00917 0.726
DOC_USP7_MATH_1 911 915 PF00917 0.531
DOC_USP7_UBL2_3 79 83 PF12436 0.529
DOC_WW_Pin1_4 167 172 PF00397 0.476
DOC_WW_Pin1_4 249 254 PF00397 0.478
DOC_WW_Pin1_4 315 320 PF00397 0.635
DOC_WW_Pin1_4 40 45 PF00397 0.324
DOC_WW_Pin1_4 443 448 PF00397 0.305
DOC_WW_Pin1_4 512 517 PF00397 0.431
DOC_WW_Pin1_4 580 585 PF00397 0.520
DOC_WW_Pin1_4 794 799 PF00397 0.613
DOC_WW_Pin1_4 813 818 PF00397 0.484
DOC_WW_Pin1_4 824 829 PF00397 0.611
DOC_WW_Pin1_4 894 899 PF00397 0.504
LIG_14-3-3_CanoR_1 107 111 PF00244 0.519
LIG_14-3-3_CanoR_1 133 143 PF00244 0.398
LIG_14-3-3_CanoR_1 271 279 PF00244 0.525
LIG_14-3-3_CanoR_1 374 380 PF00244 0.496
LIG_14-3-3_CanoR_1 495 499 PF00244 0.387
LIG_14-3-3_CanoR_1 595 604 PF00244 0.420
LIG_14-3-3_CanoR_1 703 712 PF00244 0.437
LIG_14-3-3_CanoR_1 723 733 PF00244 0.448
LIG_14-3-3_CanoR_1 822 828 PF00244 0.546
LIG_Actin_WH2_2 573 588 PF00022 0.484
LIG_Actin_WH2_2 880 897 PF00022 0.529
LIG_APCC_ABBA_1 303 308 PF00400 0.425
LIG_APCC_ABBA_1 331 336 PF00400 0.362
LIG_APCC_ABBAyCdc20_2 701 707 PF00400 0.349
LIG_BRCT_BRCA1_1 12 16 PF00533 0.339
LIG_BRCT_BRCA1_1 328 332 PF00533 0.436
LIG_BRCT_BRCA1_1 398 402 PF00533 0.436
LIG_BRCT_BRCA1_1 860 864 PF00533 0.421
LIG_EH1_1 175 183 PF00400 0.420
LIG_FHA_1 113 119 PF00498 0.443
LIG_FHA_1 255 261 PF00498 0.378
LIG_FHA_1 339 345 PF00498 0.365
LIG_FHA_1 398 404 PF00498 0.441
LIG_FHA_1 48 54 PF00498 0.323
LIG_FHA_1 544 550 PF00498 0.472
LIG_FHA_1 580 586 PF00498 0.473
LIG_FHA_1 727 733 PF00498 0.671
LIG_FHA_1 748 754 PF00498 0.656
LIG_FHA_1 814 820 PF00498 0.551
LIG_FHA_1 97 103 PF00498 0.477
LIG_FHA_2 1 7 PF00498 0.275
LIG_FHA_2 318 324 PF00498 0.489
LIG_FHA_2 648 654 PF00498 0.441
LIG_FHA_2 821 827 PF00498 0.731
LIG_FHA_2 858 864 PF00498 0.457
LIG_FHA_2 917 923 PF00498 0.450
LIG_LIR_Gen_1 327 338 PF02991 0.447
LIG_LIR_Gen_1 525 533 PF02991 0.420
LIG_LIR_Gen_1 623 634 PF02991 0.428
LIG_LIR_Gen_1 702 713 PF02991 0.402
LIG_LIR_Gen_1 861 872 PF02991 0.387
LIG_LIR_Gen_1 875 885 PF02991 0.353
LIG_LIR_Gen_1 926 936 PF02991 0.451
LIG_LIR_Nem_3 13 19 PF02991 0.350
LIG_LIR_Nem_3 188 193 PF02991 0.457
LIG_LIR_Nem_3 327 333 PF02991 0.451
LIG_LIR_Nem_3 416 422 PF02991 0.291
LIG_LIR_Nem_3 623 629 PF02991 0.428
LIG_LIR_Nem_3 675 680 PF02991 0.420
LIG_LIR_Nem_3 684 690 PF02991 0.420
LIG_LIR_Nem_3 702 708 PF02991 0.233
LIG_LIR_Nem_3 861 867 PF02991 0.411
LIG_LIR_Nem_3 875 880 PF02991 0.318
LIG_LIR_Nem_3 926 931 PF02991 0.441
LIG_LIR_Nem_3 937 942 PF02991 0.346
LIG_MYND_1 855 859 PF01753 0.678
LIG_NRBOX 293 299 PF00104 0.454
LIG_NRBOX 904 910 PF00104 0.394
LIG_PCNA_PIPBox_1 379 388 PF02747 0.411
LIG_PCNA_PIPBox_1 529 538 PF02747 0.484
LIG_PCNA_yPIPBox_3 661 671 PF02747 0.420
LIG_Pex14_2 190 194 PF04695 0.486
LIG_REV1ctd_RIR_1 153 161 PF16727 0.504
LIG_REV1ctd_RIR_1 716 727 PF16727 0.537
LIG_SH2_CRK 210 214 PF00017 0.431
LIG_SH2_CRK 330 334 PF00017 0.245
LIG_SH2_CRK 677 681 PF00017 0.431
LIG_SH2_CRK 712 716 PF00017 0.323
LIG_SH2_GRB2like 619 622 PF00017 0.486
LIG_SH2_NCK_1 712 716 PF00017 0.339
LIG_SH2_NCK_1 757 761 PF00017 0.570
LIG_SH2_PTP2 734 737 PF00017 0.682
LIG_SH2_SRC 306 309 PF00017 0.451
LIG_SH2_SRC 619 622 PF00017 0.520
LIG_SH2_SRC 757 760 PF00017 0.572
LIG_SH2_STAP1 110 114 PF00017 0.486
LIG_SH2_STAP1 712 716 PF00017 0.313
LIG_SH2_STAP1 943 947 PF00017 0.453
LIG_SH2_STAT3 19 22 PF00017 0.347
LIG_SH2_STAT5 193 196 PF00017 0.463
LIG_SH2_STAT5 212 215 PF00017 0.336
LIG_SH2_STAT5 633 636 PF00017 0.420
LIG_SH2_STAT5 734 737 PF00017 0.682
LIG_SH2_STAT5 90 93 PF00017 0.420
LIG_SH3_2 817 822 PF14604 0.524
LIG_SH3_2 851 856 PF14604 0.493
LIG_SH3_3 203 209 PF00018 0.420
LIG_SH3_3 210 216 PF00018 0.420
LIG_SH3_3 428 434 PF00018 0.475
LIG_SH3_3 465 471 PF00018 0.397
LIG_SH3_3 518 524 PF00018 0.420
LIG_SH3_3 636 642 PF00018 0.445
LIG_SH3_3 795 801 PF00018 0.648
LIG_SH3_3 814 820 PF00018 0.441
LIG_SH3_3 848 854 PF00018 0.621
LIG_SH3_3 9 15 PF00018 0.331
LIG_SUMO_SIM_anti_2 204 209 PF11976 0.508
LIG_SUMO_SIM_anti_2 228 235 PF11976 0.377
LIG_SUMO_SIM_par_1 228 235 PF11976 0.421
LIG_SUMO_SIM_par_1 252 258 PF11976 0.367
LIG_SUMO_SIM_par_1 678 685 PF11976 0.486
LIG_TRFH_1 212 216 PF08558 0.520
LIG_TYR_ITIM 732 737 PF00017 0.697
LIG_UBA3_1 331 337 PF00899 0.318
LIG_UBA3_1 552 557 PF00899 0.462
LIG_UBA3_1 625 630 PF00899 0.420
LIG_WRC_WIRS_1 573 578 PF05994 0.423
MOD_CDC14_SPxK_1 583 586 PF00782 0.520
MOD_CDK_SPxK_1 580 586 PF00069 0.520
MOD_CK1_1 167 173 PF00069 0.491
MOD_CK1_1 241 247 PF00069 0.486
MOD_CK1_1 493 499 PF00069 0.519
MOD_CK1_1 525 531 PF00069 0.498
MOD_CK1_1 749 755 PF00069 0.582
MOD_CK1_1 794 800 PF00069 0.571
MOD_CK1_1 8 14 PF00069 0.480
MOD_CK1_1 824 830 PF00069 0.652
MOD_CK2_1 296 302 PF00069 0.375
MOD_CK2_1 528 534 PF00069 0.465
MOD_CK2_1 690 696 PF00069 0.480
MOD_CK2_1 820 826 PF00069 0.730
MOD_CK2_1 832 838 PF00069 0.707
MOD_CK2_1 857 863 PF00069 0.431
MOD_CK2_1 916 922 PF00069 0.478
MOD_Cter_Amidation 720 723 PF01082 0.354
MOD_GlcNHglycan 144 147 PF01048 0.307
MOD_GlcNHglycan 160 163 PF01048 0.269
MOD_GlcNHglycan 187 190 PF01048 0.320
MOD_GlcNHglycan 245 248 PF01048 0.291
MOD_GlcNHglycan 353 356 PF01048 0.584
MOD_GlcNHglycan 441 444 PF01048 0.314
MOD_GlcNHglycan 483 486 PF01048 0.392
MOD_GlcNHglycan 539 542 PF01048 0.272
MOD_GlcNHglycan 6 10 PF01048 0.458
MOD_GlcNHglycan 785 788 PF01048 0.588
MOD_GlcNHglycan 793 796 PF01048 0.532
MOD_GlcNHglycan 823 826 PF01048 0.641
MOD_GSK3_1 129 136 PF00069 0.502
MOD_GSK3_1 142 149 PF00069 0.421
MOD_GSK3_1 238 245 PF00069 0.441
MOD_GSK3_1 311 318 PF00069 0.566
MOD_GSK3_1 346 353 PF00069 0.535
MOD_GSK3_1 40 47 PF00069 0.347
MOD_GSK3_1 434 441 PF00069 0.307
MOD_GSK3_1 490 497 PF00069 0.521
MOD_GSK3_1 512 519 PF00069 0.520
MOD_GSK3_1 568 575 PF00069 0.410
MOD_GSK3_1 699 706 PF00069 0.505
MOD_GSK3_1 820 827 PF00069 0.702
MOD_GSK3_1 828 835 PF00069 0.655
MOD_LATS_1 645 651 PF00433 0.515
MOD_N-GLC_1 620 625 PF02516 0.233
MOD_N-GLC_2 664 666 PF02516 0.231
MOD_NEK2_1 105 110 PF00069 0.441
MOD_NEK2_1 243 248 PF00069 0.467
MOD_NEK2_1 25 30 PF00069 0.424
MOD_NEK2_1 254 259 PF00069 0.321
MOD_NEK2_1 358 363 PF00069 0.498
MOD_NEK2_1 397 402 PF00069 0.411
MOD_NEK2_1 422 427 PF00069 0.311
MOD_NEK2_1 439 444 PF00069 0.298
MOD_NEK2_1 504 509 PF00069 0.371
MOD_NEK2_1 53 58 PF00069 0.314
MOD_NEK2_1 61 66 PF00069 0.355
MOD_NEK2_1 690 695 PF00069 0.507
MOD_NEK2_1 842 847 PF00069 0.695
MOD_NEK2_1 893 898 PF00069 0.601
MOD_NEK2_1 946 951 PF00069 0.520
MOD_NEK2_2 490 495 PF00069 0.403
MOD_NEK2_2 911 916 PF00069 0.444
MOD_NEK2_2 923 928 PF00069 0.343
MOD_PIKK_1 134 140 PF00454 0.512
MOD_PIKK_1 317 323 PF00454 0.497
MOD_PIKK_1 62 68 PF00454 0.548
MOD_PIKK_1 96 102 PF00454 0.437
MOD_PKA_1 106 112 PF00069 0.520
MOD_PKA_2 106 112 PF00069 0.524
MOD_PKA_2 270 276 PF00069 0.553
MOD_PKA_2 494 500 PF00069 0.378
MOD_PKA_2 699 705 PF00069 0.410
MOD_PKA_2 70 76 PF00069 0.616
MOD_PKA_2 724 730 PF00069 0.631
MOD_PKA_2 821 827 PF00069 0.757
MOD_PKA_2 836 842 PF00069 0.669
MOD_PKB_1 701 709 PF00069 0.424
MOD_Plk_1 129 135 PF00069 0.484
MOD_Plk_1 397 403 PF00069 0.399
MOD_Plk_1 422 428 PF00069 0.395
MOD_Plk_1 828 834 PF00069 0.792
MOD_Plk_4 164 170 PF00069 0.508
MOD_Plk_4 238 244 PF00069 0.462
MOD_Plk_4 326 332 PF00069 0.332
MOD_Plk_4 364 370 PF00069 0.462
MOD_Plk_4 434 440 PF00069 0.379
MOD_Plk_4 516 522 PF00069 0.478
MOD_Plk_4 528 534 PF00069 0.417
MOD_Plk_4 568 574 PF00069 0.456
MOD_Plk_4 828 834 PF00069 0.735
MOD_Plk_4 923 929 PF00069 0.572
MOD_ProDKin_1 167 173 PF00069 0.476
MOD_ProDKin_1 249 255 PF00069 0.473
MOD_ProDKin_1 315 321 PF00069 0.624
MOD_ProDKin_1 40 46 PF00069 0.335
MOD_ProDKin_1 443 449 PF00069 0.306
MOD_ProDKin_1 512 518 PF00069 0.431
MOD_ProDKin_1 580 586 PF00069 0.520
MOD_ProDKin_1 794 800 PF00069 0.614
MOD_ProDKin_1 813 819 PF00069 0.488
MOD_ProDKin_1 824 830 PF00069 0.669
MOD_ProDKin_1 894 900 PF00069 0.500
MOD_SUMO_rev_2 540 549 PF00179 0.520
MOD_SUMO_rev_2 554 559 PF00179 0.447
MOD_SUMO_rev_2 778 786 PF00179 0.546
TRG_DiLeu_BaEn_2 862 868 PF01217 0.400
TRG_DiLeu_BaEn_4 937 943 PF01217 0.477
TRG_DiLeu_BaLyEn_6 889 894 PF01217 0.503
TRG_DiLeu_BaLyEn_6 904 909 PF01217 0.261
TRG_ENDOCYTIC_2 210 213 PF00928 0.420
TRG_ENDOCYTIC_2 330 333 PF00928 0.242
TRG_ENDOCYTIC_2 526 529 PF00928 0.431
TRG_ENDOCYTIC_2 677 680 PF00928 0.425
TRG_ENDOCYTIC_2 712 715 PF00928 0.340
TRG_ENDOCYTIC_2 734 737 PF00928 0.683
TRG_ENDOCYTIC_2 877 880 PF00928 0.345
TRG_ENDOCYTIC_2 943 946 PF00928 0.400
TRG_ER_diArg_1 700 703 PF00400 0.487
TRG_ER_diArg_1 722 725 PF00400 0.444
TRG_ER_diArg_1 773 776 PF00400 0.563
TRG_NES_CRM1_1 384 398 PF08389 0.370
TRG_Pf-PMV_PEXEL_1 933 937 PF00026 0.530
TRG_Pf-PMV_PEXEL_1 940 945 PF00026 0.517

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P6K3 Leptomonas seymouri 70% 99%
A0A0P0V4R0 Oryza sativa subsp. japonica 35% 94%
A0A0S4KH73 Bodo saltans 39% 92%
A0A1X0P9Z9 Trypanosomatidae 47% 98%
A0A3R7MDU1 Trypanosoma rangeli 56% 98%
A0A3R7RLU2 Trypanosoma rangeli 24% 93%
A0A3S7WYU3 Leishmania donovani 24% 100%
A1CJ34 Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1 / QM 1276 / 107) 26% 100%
A1D8E4 Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181) 26% 100%
A2QY22 Aspergillus niger (strain CBS 513.88 / FGSC A1513) 27% 100%
A3LN13 Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545) 24% 100%
A4HDT9 Leishmania braziliensis 25% 100%
A4HHR4 Leishmania braziliensis 86% 100%
A4I136 Leishmania infantum 24% 100%
A4I4X4 Leishmania infantum 100% 100%
A4K436 Bos taurus 34% 78%
A5DNW6 Meyerozyma guilliermondii (strain ATCC 6260 / CBS 566 / DSM 6381 / JCM 1539 / NBRC 10279 / NRRL Y-324) 25% 100%
A5DUW8 Lodderomyces elongisporus (strain ATCC 11503 / CBS 2605 / JCM 1781 / NBRC 1676 / NRRL YB-4239) 24% 100%
A8MPP1 Homo sapiens 27% 100%
A8WS58 Caenorhabditis briggsae 32% 96%
B0W9F4 Culex quinquefasciatus 32% 97%
B3MSG8 Drosophila ananassae 32% 96%
B3NSW1 Drosophila erecta 33% 97%
B4GU19 Drosophila persimilis 33% 94%
B4I0K4 Drosophila sechellia 32% 99%
B4JNS2 Drosophila grimshawi 33% 97%
B4L1Z2 Drosophila mojavensis 32% 94%
B4M891 Drosophila virilis 32% 95%
B4NDG5 Drosophila willistoni 33% 95%
B4PZB4 Drosophila yakuba 34% 97%
C9ZKX7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 48% 99%
E9AEC8 Leishmania major 93% 100%
E9ALF8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%
E9AX74 Leishmania mexicana (strain MHOM/GT/2001/U1103) 24% 100%
F1R345 Danio rerio 29% 100%
F4HQE2 Arabidopsis thaliana 34% 92%
O14147 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 26% 100%
P06839 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 26% 100%
P0C928 Danio rerio 32% 81%
Q0VGM9 Mus musculus 34% 79%
Q16X92 Aedes aegypti 33% 94%
Q1E5T3 Coccidioides immitis (strain RS) 28% 100%
Q21489 Caenorhabditis elegans 24% 100%
Q29FS3 Drosophila pseudoobscura pseudoobscura 33% 94%
Q2U587 Aspergillus oryzae (strain ATCC 42149 / RIB 40) 27% 100%
Q3YK19 Gallus gallus 29% 76%
Q4QAA2 Leishmania major 25% 100%
Q4WWE9 Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) 27% 100%
Q55G81 Dictyostelium discoideum 26% 100%
Q5AD67 Candida albicans (strain SC5314 / ATCC MYA-2876) 26% 100%
Q5RE34 Pongo abelii 32% 73%
Q5RJZ1 Rattus norvegicus 33% 75%
Q6AXC6 Mus musculus 28% 100%
Q6BZD9 Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / BCRC 21394 / JCM 1990 / NBRC 0083 / IGC 2968) 25% 100%
Q6CAX3 Yarrowia lipolytica (strain CLIB 122 / E 150) 26% 100%
Q6CIF0 Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) 25% 100%
Q6FKT4 Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) 24% 100%
Q6H1L8 Mus spretus 34% 79%
Q7QEI1 Anopheles gambiae 33% 96%
Q92771 Homo sapiens 27% 100%
Q93575 Caenorhabditis elegans 31% 96%
Q96FC9 Homo sapiens 28% 98%
Q9BX63 Homo sapiens 29% 76%
Q9NZ71 Homo sapiens 33% 78%
Q9W484 Drosophila melanogaster 33% 97%
V5B587 Trypanosoma cruzi 24% 100%
V5BAP9 Trypanosoma cruzi 28% 100%
V5BX91 Trypanosoma cruzi 50% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS