LeishMANIAdb
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Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Hypothetical_protein_conserved
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7X2S9_LEIDO
TriTrypDb:
LdBPK_292640.1 , LdCL_290032500 , LDHU3_29.3910
Length:
67

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 9
NetGPI no yes: 0, no: 9
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X2S9
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X2S9

Putative motif mimicry

Leishmania From To Domain/Motif Score
DEG_Nend_UBRbox_1 1 4 PF02207 0.530
DOC_PP4_MxPP_1 38 41 PF00568 0.638
DOC_USP7_MATH_1 14 18 PF00917 0.528
DOC_WW_Pin1_4 10 15 PF00397 0.501
LIG_FHA_1 11 17 PF00498 0.529
LIG_FHA_2 60 66 PF00498 0.646
LIG_SH3_2 41 46 PF14604 0.680
LIG_SH3_3 38 44 PF00018 0.643
MOD_CK1_1 59 65 PF00069 0.728
MOD_CK2_1 3 9 PF00069 0.503
MOD_CK2_1 59 65 PF00069 0.646
MOD_GSK3_1 8 15 PF00069 0.516
MOD_N-GLC_1 34 39 PF02516 0.646
MOD_NEK2_1 1 6 PF00069 0.508
MOD_Plk_1 34 40 PF00069 0.606
MOD_Plk_1 59 65 PF00069 0.646
MOD_Plk_4 14 20 PF00069 0.554
MOD_Plk_4 59 65 PF00069 0.646
MOD_ProDKin_1 10 16 PF00069 0.505

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P6J3 Leptomonas seymouri 81% 100%
A0A0S4IVA2 Bodo saltans 52% 93%
A4HHQ2 Leishmania braziliensis 84% 100%
A4I4W7 Leishmania infantum 100% 100%
C9ZKZ3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 51% 91%
E9AEB5 Leishmania major 97% 100%
E9ALH1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 97% 100%
V5BSW6 Trypanosoma cruzi 56% 96%

Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS