BRCT domain-containing protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, unknown function

Species:

Leishmania donovani

UniProt:

A0A3S7X2Q7_LEIDO

TriTrypDb:

LdBPK_292090.1 , LdCL_290026800 , LDHU3_29.2980

Length:

266

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X2Q7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X2Q7

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	143	145	PF00675	0.590
CLV_NRD_NRD_1	187	189	PF00675	0.731
CLV_NRD_NRD_1	207	209	PF00675	0.559
CLV_PCSK_KEX2_1	143	145	PF00082	0.590
CLV_PCSK_KEX2_1	187	189	PF00082	0.641
CLV_PCSK_KEX2_1	206	208	PF00082	0.494
CLV_PCSK_KEX2_1	243	245	PF00082	0.503
CLV_PCSK_PC1ET2_1	243	245	PF00082	0.503
CLV_PCSK_SKI1_1	220	224	PF00082	0.500
CLV_PCSK_SKI1_1	29	33	PF00082	0.483
CLV_PCSK_SKI1_1	86	90	PF00082	0.539
DEG_APCC_DBOX_1	110	118	PF00400	0.576
DOC_CKS1_1	82	87	PF01111	0.532
DOC_CYCLIN_RxL_1	26	36	PF00134	0.508
DOC_MAPK_gen_1	220	228	PF00069	0.497
DOC_PP4_FxxP_1	209	212	PF00568	0.617
DOC_PP4_MxPP_1	190	193	PF00568	0.628
DOC_USP7_MATH_1	161	165	PF00917	0.690
DOC_USP7_MATH_1	173	177	PF00917	0.578
DOC_USP7_MATH_1	54	58	PF00917	0.523
DOC_WW_Pin1_4	81	86	PF00397	0.577
LIG_14-3-3_CanoR_1	206	212	PF00244	0.621
LIG_14-3-3_CanoR_1	220	226	PF00244	0.517
LIG_BRCT_BRCA1_1	163	167	PF00533	0.783
LIG_CSL_BTD_1	82	85	PF09270	0.471
LIG_FHA_1	38	44	PF00498	0.514
LIG_FHA_1	51	57	PF00498	0.430
LIG_HP1_1	137	141	PF01393	0.546
LIG_IRF3_LxIS_1	28	34	PF10401	0.489
LIG_LIR_Gen_1	164	173	PF02991	0.645
LIG_LIR_Nem_3	164	170	PF02991	0.649
LIG_SH2_STAT5	55	58	PF00017	0.520
LIG_SH3_3	189	195	PF00018	0.626
LIG_SH3_3	210	216	PF00018	0.773
LIG_SUMO_SIM_anti_2	113	118	PF11976	0.562
LIG_SUMO_SIM_anti_2	76	82	PF11976	0.481
LIG_SUMO_SIM_par_1	29	34	PF11976	0.481
LIG_UBA3_1	166	174	PF00899	0.617
LIG_WW_3	191	195	PF00397	0.620
MOD_CDK_SPK_2	81	86	PF00069	0.476
MOD_CK1_1	94	100	PF00069	0.568
MOD_CK2_1	128	134	PF00069	0.636
MOD_CK2_1	33	39	PF00069	0.509
MOD_GlcNHglycan	157	160	PF01048	0.619
MOD_GlcNHglycan	175	178	PF01048	0.483
MOD_GlcNHglycan	181	184	PF01048	0.644
MOD_GlcNHglycan	209	212	PF01048	0.658
MOD_GlcNHglycan	233	236	PF01048	0.634
MOD_GlcNHglycan	56	59	PF01048	0.514
MOD_GlcNHglycan	61	64	PF01048	0.439
MOD_GSK3_1	106	113	PF00069	0.686
MOD_GSK3_1	128	135	PF00069	0.790
MOD_GSK3_1	31	38	PF00069	0.496
MOD_GSK3_1	50	57	PF00069	0.387
MOD_NEK2_1	106	111	PF00069	0.617
MOD_NEK2_1	226	231	PF00069	0.498
MOD_NEK2_1	31	36	PF00069	0.490
MOD_NEK2_1	48	53	PF00069	0.393
MOD_NEK2_1	89	94	PF00069	0.504
MOD_NEK2_2	91	96	PF00069	0.525
MOD_PIKK_1	106	112	PF00454	0.596
MOD_PIKK_1	258	264	PF00454	0.476
MOD_PIKK_1	65	71	PF00454	0.426
MOD_PKA_1	207	213	PF00069	0.622
MOD_PKA_2	110	116	PF00069	0.587
MOD_PKA_2	207	213	PF00069	0.622
MOD_Plk_4	110	116	PF00069	0.540
MOD_Plk_4	221	227	PF00069	0.496
MOD_ProDKin_1	81	87	PF00069	0.569
MOD_SUMO_rev_2	34	43	PF00179	0.513
TRG_DiLeu_BaLyEn_6	27	32	PF01217	0.511
TRG_ER_diArg_1	143	145	PF00400	0.590
TRG_ER_diArg_1	187	189	PF00400	0.641
TRG_ER_diArg_1	206	208	PF00400	0.494
TRG_ER_diArg_1	27	30	PF00400	0.571
TRG_NLS_Bipartite_1	187	207	PF00514	0.629
TRG_NLS_MonoExtC_3	202	207	PF00514	0.635

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4I4Q5	Leishmania infantum	100%	100%