NLI interacting factor-like phosphatase, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

NLI interacting factor-like phosphatase, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X2Q4_LEIDO

TriTrypDb:

LdBPK_292510.1 , LdCL_290031200 , LDHU3_29.3740

Length:

399

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X2Q4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X2Q4

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	157	161	PF00656	0.604
CLV_C14_Caspase3-7	189	193	PF00656	0.580
CLV_NRD_NRD_1	11	13	PF00675	0.551
CLV_NRD_NRD_1	134	136	PF00675	0.558
CLV_NRD_NRD_1	362	364	PF00675	0.371
CLV_PCSK_FUR_1	9	13	PF00082	0.543
CLV_PCSK_KEX2_1	11	13	PF00082	0.563
CLV_PCSK_KEX2_1	186	188	PF00082	0.627
CLV_PCSK_KEX2_1	240	242	PF00082	0.314
CLV_PCSK_KEX2_1	362	364	PF00082	0.450
CLV_PCSK_KEX2_1	376	378	PF00082	0.356
CLV_PCSK_PC1ET2_1	186	188	PF00082	0.627
CLV_PCSK_PC1ET2_1	240	242	PF00082	0.314
CLV_PCSK_PC1ET2_1	376	378	PF00082	0.388
CLV_PCSK_SKI1_1	249	253	PF00082	0.244
CLV_PCSK_SKI1_1	311	315	PF00082	0.262
CLV_PCSK_SKI1_1	362	366	PF00082	0.505
CLV_PCSK_SKI1_1	48	52	PF00082	0.459
DEG_Nend_UBRbox_1	1	4	PF02207	0.548
DOC_CKS1_1	32	37	PF01111	0.537
DOC_CKS1_1	53	58	PF01111	0.452
DOC_CKS1_1	99	104	PF01111	0.555
DOC_CYCLIN_yCln2_LP_2	208	211	PF00134	0.327
DOC_MAPK_gen_1	240	247	PF00069	0.311
DOC_MAPK_gen_1	249	259	PF00069	0.223
DOC_MAPK_gen_1	376	385	PF00069	0.350
DOC_MAPK_MEF2A_6	219	226	PF00069	0.262
DOC_MAPK_MEF2A_6	387	395	PF00069	0.315
DOC_PP2B_LxvP_1	208	211	PF13499	0.327
DOC_PP4_FxxP_1	335	338	PF00568	0.262
DOC_PP4_FxxP_1	364	367	PF00568	0.322
DOC_PP4_FxxP_1	53	56	PF00568	0.449
DOC_USP7_MATH_1	166	170	PF00917	0.593
DOC_USP7_MATH_1	179	183	PF00917	0.636
DOC_USP7_MATH_1	326	330	PF00917	0.262
DOC_USP7_MATH_1	91	95	PF00917	0.588
DOC_USP7_MATH_1	97	101	PF00917	0.621
DOC_WW_Pin1_4	139	144	PF00397	0.532
DOC_WW_Pin1_4	149	154	PF00397	0.532
DOC_WW_Pin1_4	31	36	PF00397	0.555
DOC_WW_Pin1_4	315	320	PF00397	0.262
DOC_WW_Pin1_4	363	368	PF00397	0.384
DOC_WW_Pin1_4	394	399	PF00397	0.379
DOC_WW_Pin1_4	52	57	PF00397	0.423
DOC_WW_Pin1_4	98	103	PF00397	0.584
LIG_14-3-3_CanoR_1	106	110	PF00244	0.551
LIG_14-3-3_CanoR_1	31	35	PF00244	0.568
LIG_14-3-3_CanoR_1	327	331	PF00244	0.261
LIG_14-3-3_CanoR_1	362	367	PF00244	0.370
LIG_14-3-3_CanoR_1	48	57	PF00244	0.392
LIG_BRCT_BRCA1_1	141	145	PF00533	0.568
LIG_BRCT_BRCA1_1	99	103	PF00533	0.555
LIG_EVH1_2	72	76	PF00568	0.554
LIG_FHA_1	168	174	PF00498	0.624
LIG_FHA_1	201	207	PF00498	0.473
LIG_FHA_1	291	297	PF00498	0.257
LIG_FHA_1	316	322	PF00498	0.251
LIG_FHA_1	32	38	PF00498	0.537
LIG_FHA_1	347	353	PF00498	0.314
LIG_FHA_1	83	89	PF00498	0.534
LIG_FHA_2	155	161	PF00498	0.576
LIG_FHA_2	169	175	PF00498	0.580
LIG_FHA_2	19	25	PF00498	0.564
LIG_FHA_2	49	55	PF00498	0.449
LIG_GBD_Chelix_1	222	230	PF00786	0.262
LIG_LIR_Apic_2	333	338	PF02991	0.266
LIG_LIR_Apic_2	39	45	PF02991	0.620
LIG_LIR_Apic_2	51	56	PF02991	0.419
LIG_LIR_Gen_1	115	124	PF02991	0.531
LIG_LIR_Gen_1	355	364	PF02991	0.303
LIG_LIR_Gen_1	54	64	PF02991	0.467
LIG_LIR_Nem_3	115	120	PF02991	0.608
LIG_LIR_Nem_3	355	360	PF02991	0.262
LIG_LIR_Nem_3	54	60	PF02991	0.443
LIG_MAD2	311	319	PF02301	0.314
LIG_MYND_1	36	40	PF01753	0.578
LIG_PDZ_Class_1	394	399	PF00595	0.379
LIG_Pex14_2	357	361	PF04695	0.299
LIG_Pex14_2	53	57	PF04695	0.448
LIG_SH2_CRK	239	243	PF00017	0.262
LIG_SH2_CRK	42	46	PF00017	0.517
LIG_SH2_STAP1	232	236	PF00017	0.276
LIG_SH2_STAP1	267	271	PF00017	0.262
LIG_SH2_STAT3	343	346	PF00017	0.314
LIG_SH2_STAT5	283	286	PF00017	0.291
LIG_SH2_STAT5	59	62	PF00017	0.472
LIG_SH3_3	140	146	PF00018	0.568
LIG_SH3_3	173	179	PF00018	0.537
LIG_SH3_3	195	201	PF00018	0.493
LIG_SH3_3	208	214	PF00018	0.339
LIG_SH3_3	334	340	PF00018	0.308
LIG_SH3_3	392	398	PF00018	0.338
LIG_SH3_3	96	102	PF00018	0.647
LIG_SUMO_SIM_anti_2	205	210	PF11976	0.400
LIG_SUMO_SIM_anti_2	310	316	PF11976	0.262
LIG_SUMO_SIM_anti_2	349	355	PF11976	0.314
LIG_SUMO_SIM_par_1	174	182	PF11976	0.579
LIG_SUMO_SIM_par_1	219	225	PF11976	0.262
LIG_SUMO_SIM_par_1	310	316	PF11976	0.262
LIG_SxIP_EBH_1	202	213	PF03271	0.453
LIG_UBA3_1	247	254	PF00899	0.262
LIG_WW_3	210	214	PF00397	0.414
MOD_CK1_1	130	136	PF00069	0.541
MOD_CK1_1	151	157	PF00069	0.573
MOD_CK1_1	182	188	PF00069	0.634
MOD_CK1_1	4	10	PF00069	0.548
MOD_CK2_1	48	54	PF00069	0.514
MOD_CK2_1	55	61	PF00069	0.590
MOD_Cter_Amidation	133	136	PF01082	0.595
MOD_GlcNHglycan	132	135	PF01048	0.596
MOD_GlcNHglycan	154	157	PF01048	0.683
MOD_GlcNHglycan	61	65	PF01048	0.663
MOD_GSK3_1	144	151	PF00069	0.589
MOD_GSK3_1	152	159	PF00069	0.570
MOD_GSK3_1	168	175	PF00069	0.454
MOD_GSK3_1	188	195	PF00069	0.556
MOD_GSK3_1	196	203	PF00069	0.490
MOD_GSK3_1	226	233	PF00069	0.292
MOD_GSK3_1	372	379	PF00069	0.463
MOD_GSK3_1	48	55	PF00069	0.573
MOD_GSK3_1	71	78	PF00069	0.703
MOD_N-GLC_1	18	23	PF02516	0.565
MOD_NEK2_1	1	6	PF00069	0.568
MOD_NEK2_1	202	207	PF00069	0.611
MOD_NEK2_1	226	231	PF00069	0.289
MOD_NEK2_1	247	252	PF00069	0.270
MOD_NEK2_1	60	65	PF00069	0.520
MOD_NEK2_2	179	184	PF00069	0.548
MOD_PK_1	348	354	PF00069	0.259
MOD_PKA_1	362	368	PF00069	0.371
MOD_PKA_1	376	382	PF00069	0.295
MOD_PKA_2	1	7	PF00069	0.568
MOD_PKA_2	105	111	PF00069	0.641
MOD_PKA_2	30	36	PF00069	0.531
MOD_PKA_2	326	332	PF00069	0.267
MOD_PKA_2	362	368	PF00069	0.351
MOD_PKA_2	376	382	PF00069	0.364
MOD_Plk_1	226	232	PF00069	0.262
MOD_Plk_1	346	352	PF00069	0.314
MOD_Plk_4	204	210	PF00069	0.400
MOD_Plk_4	226	232	PF00069	0.262
MOD_Plk_4	287	293	PF00069	0.226
MOD_Plk_4	317	323	PF00069	0.262
MOD_Plk_4	326	332	PF00069	0.262
MOD_Plk_4	348	354	PF00069	0.405
MOD_ProDKin_1	139	145	PF00069	0.532
MOD_ProDKin_1	149	155	PF00069	0.533
MOD_ProDKin_1	31	37	PF00069	0.556
MOD_ProDKin_1	315	321	PF00069	0.262
MOD_ProDKin_1	363	369	PF00069	0.378
MOD_ProDKin_1	52	58	PF00069	0.426
MOD_ProDKin_1	98	104	PF00069	0.584
TRG_DiLeu_BaEn_2	385	391	PF01217	0.371
TRG_DiLeu_BaLyEn_6	300	305	PF01217	0.330
TRG_DiLeu_BaLyEn_6	33	38	PF01217	0.562
TRG_DiLeu_BaLyEn_6	45	50	PF01217	0.448
TRG_ER_diArg_1	361	363	PF00400	0.363
TRG_ER_diArg_1	9	12	PF00400	0.533
TRG_Pf-PMV_PEXEL_1	311	316	PF00026	0.346

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HTZ3	Leptomonas seymouri	49%	90%
A4I4V4	Leishmania infantum	99%	100%
E9ALI4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
Q4I099	Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1)	23%	76%
Q5B4P0	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	24%	75%