LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7X2N0_LEIDO
TriTrypDb:
LdBPK_291650.1 , LdCL_290022100 , LDHU3_29.2390
Length:
192

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X2N0
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X2N0

PDB structure(s): 7ane_g

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 15 17 PF00675 0.419
CLV_NRD_NRD_1 151 153 PF00675 0.418
CLV_NRD_NRD_1 159 161 PF00675 0.486
CLV_NRD_NRD_1 58 60 PF00675 0.348
CLV_NRD_NRD_1 97 99 PF00675 0.403
CLV_PCSK_KEX2_1 159 161 PF00082 0.464
CLV_PCSK_KEX2_1 58 60 PF00082 0.365
CLV_PCSK_KEX2_1 96 98 PF00082 0.381
CLV_PCSK_SKI1_1 114 118 PF00082 0.360
DEG_Nend_UBRbox_3 1 3 PF02207 0.655
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P947 Leptomonas seymouri 86% 100%
A0A0S4KFE4 Bodo saltans 59% 100%
A0A1X0P098 Trypanosomatidae 76% 99%
A0A422NEG3 Trypanosoma rangeli 79% 100%
A4HHG6 Leishmania braziliensis 91% 100%
A4I4L5 Leishmania infantum 99% 100%
C9ZLA3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 74% 99%
E9AE13 Leishmania major 97% 100%
E9ALS0 Leishmania mexicana (strain MHOM/GT/2001/U1103) 97% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS