Thioredoxin, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

thioredoxin, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X2I2_LEIDO

TriTrypDb:

LdBPK_291790.1 , LdCL_290023500 , LDHU3_29.2570

Length:

451

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X2I2

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X2I2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	321	325	PF00656	0.678
CLV_NRD_NRD_1	62	64	PF00675	0.732
CLV_PCSK_KEX2_1	446	448	PF00082	0.574
CLV_PCSK_KEX2_1	62	64	PF00082	0.732
CLV_PCSK_PC1ET2_1	446	448	PF00082	0.644
CLV_PCSK_SKI1_1	232	236	PF00082	0.450
CLV_PCSK_SKI1_1	323	327	PF00082	0.579
DEG_Nend_Nbox_1	1	3	PF02207	0.671
DOC_CKS1_1	38	43	PF01111	0.693
DOC_MAPK_gen_1	230	239	PF00069	0.493
DOC_MAPK_gen_1	79	87	PF00069	0.625
DOC_PP1_RVXF_1	233	240	PF00149	0.482
DOC_USP7_MATH_1	113	117	PF00917	0.661
DOC_USP7_MATH_1	123	127	PF00917	0.568
DOC_USP7_MATH_1	140	144	PF00917	0.704
DOC_USP7_MATH_1	173	177	PF00917	0.716
DOC_USP7_MATH_1	32	36	PF00917	0.591
DOC_USP7_MATH_1	358	362	PF00917	0.285
DOC_USP7_MATH_1	419	423	PF00917	0.538
DOC_WW_Pin1_4	143	148	PF00397	0.571
DOC_WW_Pin1_4	169	174	PF00397	0.666
DOC_WW_Pin1_4	186	191	PF00397	0.699
DOC_WW_Pin1_4	195	200	PF00397	0.644
DOC_WW_Pin1_4	209	214	PF00397	0.591
DOC_WW_Pin1_4	288	293	PF00397	0.610
DOC_WW_Pin1_4	303	308	PF00397	0.595
DOC_WW_Pin1_4	37	42	PF00397	0.694
DOC_WW_Pin1_4	423	428	PF00397	0.714
DOC_WW_Pin1_4	430	435	PF00397	0.644
DOC_WW_Pin1_4	89	94	PF00397	0.661
DOC_WW_Pin1_4	95	100	PF00397	0.623
LIG_14-3-3_CanoR_1	101	107	PF00244	0.501
LIG_14-3-3_CanoR_1	110	118	PF00244	0.522
LIG_14-3-3_CanoR_1	25	31	PF00244	0.780
LIG_14-3-3_CanoR_1	39	45	PF00244	0.535
LIG_14-3-3_CanoR_1	425	434	PF00244	0.592
LIG_14-3-3_CanoR_1	54	60	PF00244	0.523
LIG_14-3-3_CanoR_1	81	86	PF00244	0.556
LIG_BRCT_BRCA1_1	175	179	PF00533	0.636
LIG_Clathr_ClatBox_1	368	372	PF01394	0.363
LIG_FHA_1	204	210	PF00498	0.810
LIG_FHA_1	330	336	PF00498	0.666
LIG_FHA_1	337	343	PF00498	0.600
LIG_FHA_2	103	109	PF00498	0.568
LIG_FHA_2	144	150	PF00498	0.517
LIG_FHA_2	273	279	PF00498	0.654
LIG_FHA_2	339	345	PF00498	0.663
LIG_FHA_2	54	60	PF00498	0.637
LIG_FHA_2	69	75	PF00498	0.583
LIG_LIR_Gen_1	176	183	PF02991	0.564
LIG_LIR_Gen_1	3	14	PF02991	0.501
LIG_LIR_Nem_3	3	9	PF02991	0.495
LIG_LIR_Nem_3	390	394	PF02991	0.433
LIG_MYND_1	199	203	PF01753	0.553
LIG_NRBOX	413	419	PF00104	0.550
LIG_REV1ctd_RIR_1	237	246	PF16727	0.484
LIG_SH2_SRC	319	322	PF00017	0.606
LIG_SH2_STAT3	296	299	PF00017	0.538
LIG_SH2_STAT5	2	5	PF00017	0.585
LIG_SH2_STAT5	296	299	PF00017	0.547
LIG_SH3_3	196	202	PF00018	0.707
LIG_SH3_3	210	216	PF00018	0.631
LIG_SH3_3	28	34	PF00018	0.622
LIG_SH3_3	301	307	PF00018	0.580
LIG_SH3_5	292	296	PF00018	0.515
LIG_SUMO_SIM_anti_2	365	370	PF11976	0.433
LIG_SUMO_SIM_par_1	365	370	PF11976	0.423
LIG_TRAF2_1	438	441	PF00917	0.563
LIG_WRC_WIRS_1	217	222	PF05994	0.576
LIG_WRC_WIRS_1	388	393	PF05994	0.433
LIG_WW_2	199	202	PF00397	0.550
MOD_CDC14_SPxK_1	98	101	PF00782	0.585
MOD_CDK_SPxK_1	95	101	PF00069	0.578
MOD_CK1_1	126	132	PF00069	0.595
MOD_CK1_1	143	149	PF00069	0.584
MOD_CK1_1	152	158	PF00069	0.666
MOD_CK1_1	160	166	PF00069	0.654
MOD_CK1_1	267	273	PF00069	0.576
MOD_CK1_1	387	393	PF00069	0.433
MOD_CK1_1	426	432	PF00069	0.733
MOD_CK2_1	102	108	PF00069	0.521
MOD_CK2_1	201	207	PF00069	0.726
MOD_CK2_1	272	278	PF00069	0.653
MOD_CK2_1	89	95	PF00069	0.561
MOD_Cter_Amidation	60	63	PF01082	0.636
MOD_GlcNHglycan	151	154	PF01048	0.525
MOD_GlcNHglycan	174	178	PF01048	0.704
MOD_GlcNHglycan	203	206	PF01048	0.653
MOD_GlcNHglycan	266	269	PF01048	0.673
MOD_GlcNHglycan	275	278	PF01048	0.734
MOD_GlcNHglycan	310	313	PF01048	0.730
MOD_GlcNHglycan	448	451	PF01048	0.700
MOD_GSK3_1	109	116	PF00069	0.722
MOD_GSK3_1	143	150	PF00069	0.656
MOD_GSK3_1	169	176	PF00069	0.723
MOD_GSK3_1	331	338	PF00069	0.711
MOD_GSK3_1	358	365	PF00069	0.269
MOD_GSK3_1	419	426	PF00069	0.648
MOD_GSK3_1	442	449	PF00069	0.783
MOD_GSK3_1	91	98	PF00069	0.567
MOD_N-GLC_1	420	425	PF02516	0.574
MOD_N-GLC_1	430	435	PF02516	0.632
MOD_N-GLC_2	396	398	PF02516	0.433
MOD_NEK2_1	362	367	PF00069	0.489
MOD_NEK2_1	68	73	PF00069	0.640
MOD_NEK2_2	216	221	PF00069	0.584
MOD_NEK2_2	4	9	PF00069	0.564
MOD_PIKK_1	157	163	PF00454	0.632
MOD_PIKK_1	403	409	PF00454	0.395
MOD_PK_1	83	89	PF00069	0.558
MOD_PKA_2	109	115	PF00069	0.622
MOD_PKA_2	53	59	PF00069	0.719
MOD_PKB_1	79	87	PF00069	0.625
MOD_Plk_1	377	383	PF00069	0.433
MOD_Plk_4	26	32	PF00069	0.715
MOD_Plk_4	362	368	PF00069	0.433
MOD_Plk_4	387	393	PF00069	0.433
MOD_ProDKin_1	143	149	PF00069	0.572
MOD_ProDKin_1	169	175	PF00069	0.743
MOD_ProDKin_1	186	192	PF00069	0.701
MOD_ProDKin_1	195	201	PF00069	0.643
MOD_ProDKin_1	209	215	PF00069	0.576
MOD_ProDKin_1	288	294	PF00069	0.613
MOD_ProDKin_1	303	309	PF00069	0.597
MOD_ProDKin_1	37	43	PF00069	0.694
MOD_ProDKin_1	423	429	PF00069	0.715
MOD_ProDKin_1	430	436	PF00069	0.643
MOD_ProDKin_1	89	95	PF00069	0.661
MOD_SUMO_rev_2	321	328	PF00179	0.601
MOD_SUMO_rev_2	343	347	PF00179	0.616
TRG_DiLeu_BaEn_1	410	415	PF01217	0.433
TRG_DiLeu_BaLyEn_6	289	294	PF01217	0.611
TRG_DiLeu_BaLyEn_6	86	91	PF01217	0.722
TRG_ER_diArg_1	130	133	PF00400	0.620
TRG_ER_diArg_1	22	25	PF00400	0.695
TRG_ER_diArg_1	80	83	PF00400	0.559
TRG_Pf-PMV_PEXEL_1	353	357	PF00026	0.474
TRG_Pf-PMV_PEXEL_1	83	88	PF00026	0.557

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4HHH9	Leishmania braziliensis	62%	100%