Heat_shock_protein_100_kDa/GeneDB:LmjF.29.1270

Quick info Annotations Localization Phosphorylation Abundance Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

ATP-dependent Clp protease subunit, heat shock protein 100 (HSP100), putative

Species:

Leishmania donovani

UniProt:

A0A3S7X2C6_LEIDO

TriTrypDb:

LdBPK_291360.1 , LdCL_290018700 , LDHU3_29.1850

Length:

867

Annotations

Annotations by Jardim et al.

Proteases, ATP-dependent Clp protease subunit, heat shock 100 (HSP100)

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	yes	yes: 4
Forrest at al. (procyclic)	yes	yes: 4
Silverman et al.	no	yes: 0
Pissara et al.	yes	yes: 15

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 5

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	yes	yes: 10

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

Phosphorylation

Amastigote: 150

Abundance

Amastigote (protein)


Source	Evidence on protein	Close homologs
Pescher et al. (upgregulation)	no	yes: 0

Promastigote and amastigote


Source	Evidence on protein	Close homologs
Lahav et al. - mRNA - Protein

Expansion

Sequence features

A0A3S7X2C6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X2C6

PDB structure(s): 7tfm_A

Function

Biological processes
Term	Name	Level	Count
GO:0006950	response to stress	2	1
GO:0009266	response to temperature stimulus	3	1
GO:0009408	response to heat	3	1
GO:0009628	response to abiotic stimulus	2	1
GO:0009987	cellular process	1	1
GO:0033554	cellular response to stress	3	1
GO:0034605	cellular response to heat	4	1
GO:0050896	response to stimulus	1	1
GO:0051716	cellular response to stimulus	2	1
GO:0006508	proteolysis	4	6
GO:0006807	nitrogen compound metabolic process	2	6
GO:0008152	metabolic process	1	6
GO:0019538	protein metabolic process	3	6
GO:0043170	macromolecule metabolic process	3	6
GO:0044238	primary metabolic process	2	6
GO:0071704	organic substance metabolic process	2	6
GO:1901564	organonitrogen compound metabolic process	3	6

Molecular functions
Term	Name	Level	Count
GO:0000166	nucleotide binding	3	11
GO:0003824	catalytic activity	1	11
GO:0005488	binding	1	11
GO:0005524	ATP binding	5	11
GO:0016462	pyrophosphatase activity	5	11
GO:0016787	hydrolase activity	2	11
GO:0016817	hydrolase activity, acting on acid anhydrides	3	11
GO:0016818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4	11
GO:0016887	ATP hydrolysis activity	7	11
GO:0017076	purine nucleotide binding	4	11
GO:0017111	ribonucleoside triphosphate phosphatase activity	6	11
GO:0030554	adenyl nucleotide binding	5	11
GO:0032553	ribonucleotide binding	3	11
GO:0032555	purine ribonucleotide binding	4	11
GO:0032559	adenyl ribonucleotide binding	5	11
GO:0035639	purine ribonucleoside triphosphate binding	4	11
GO:0036094	small molecule binding	2	11
GO:0043167	ion binding	2	11
GO:0043168	anion binding	3	11
GO:0097159	organic cyclic compound binding	2	11
GO:0097367	carbohydrate derivative binding	2	11
GO:1901265	nucleoside phosphate binding	3	11
GO:1901363	heterocyclic compound binding	2	11
GO:0008233	peptidase activity	3	6
GO:0140096	catalytic activity, acting on a protein	2	6

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	59	63	PF00656	0.486
CLV_NRD_NRD_1	142	144	PF00675	0.299
CLV_NRD_NRD_1	195	197	PF00675	0.489
CLV_NRD_NRD_1	23	25	PF00675	0.295
CLV_NRD_NRD_1	330	332	PF00675	0.441
CLV_NRD_NRD_1	415	417	PF00675	0.335
CLV_NRD_NRD_1	52	54	PF00675	0.351
CLV_NRD_NRD_1	668	670	PF00675	0.295
CLV_NRD_NRD_1	746	748	PF00675	0.348
CLV_NRD_NRD_1	819	821	PF00675	0.332
CLV_PCSK_FUR_1	416	420	PF00082	0.379
CLV_PCSK_KEX2_1	195	197	PF00082	0.489
CLV_PCSK_KEX2_1	330	332	PF00082	0.430
CLV_PCSK_KEX2_1	418	420	PF00082	0.358
CLV_PCSK_KEX2_1	667	669	PF00082	0.295
CLV_PCSK_KEX2_1	819	821	PF00082	0.332
CLV_PCSK_KEX2_1	861	863	PF00082	0.534
CLV_PCSK_PC1ET2_1	418	420	PF00082	0.380
CLV_PCSK_PC1ET2_1	861	863	PF00082	0.534
CLV_PCSK_PC7_1	191	197	PF00082	0.438
CLV_PCSK_SKI1_1	259	263	PF00082	0.332
CLV_PCSK_SKI1_1	271	275	PF00082	0.332
CLV_PCSK_SKI1_1	299	303	PF00082	0.332
CLV_PCSK_SKI1_1	350	354	PF00082	0.332
CLV_PCSK_SKI1_1	378	382	PF00082	0.332
CLV_PCSK_SKI1_1	441	445	PF00082	0.311
CLV_PCSK_SKI1_1	481	485	PF00082	0.587
CLV_PCSK_SKI1_1	513	517	PF00082	0.447
CLV_PCSK_SKI1_1	747	751	PF00082	0.389
CLV_PCSK_SKI1_1	770	774	PF00082	0.335
CLV_PCSK_SKI1_1	824	828	PF00082	0.359
CLV_PCSK_SKI1_1	98	102	PF00082	0.326
CLV_Separin_Metazoa	185	189	PF03568	0.396
CLV_Separin_Metazoa	664	668	PF03568	0.495
DEG_APCC_DBOX_1	135	143	PF00400	0.589
DEG_APCC_DBOX_1	303	311	PF00400	0.332
DEG_APCC_DBOX_1	555	563	PF00400	0.458
DOC_CDC14_PxL_1	502	510	PF14671	0.482
DOC_CYCLIN_RxL_1	296	306	PF00134	0.463
DOC_CYCLIN_RxL_1	555	564	PF00134	0.478
DOC_CYCLIN_RxL_1	762	773	PF00134	0.364
DOC_CYCLIN_yClb5_NLxxxL_5	292	301	PF00134	0.463
DOC_CYCLIN_yCln2_LP_2	297	303	PF00134	0.340
DOC_MAPK_DCC_7	26	36	PF00069	0.515
DOC_MAPK_gen_1	195	204	PF00069	0.419
DOC_MAPK_gen_1	330	337	PF00069	0.420
DOC_MAPK_gen_1	416	423	PF00069	0.332
DOC_MAPK_gen_1	667	676	PF00069	0.495
DOC_MAPK_gen_1	786	794	PF00069	0.350
DOC_MAPK_MEF2A_6	330	337	PF00069	0.420
DOC_MAPK_MEF2A_6	627	634	PF00069	0.495
DOC_MAPK_MEF2A_6	788	796	PF00069	0.350
DOC_PP1_RVXF_1	269	276	PF00149	0.455
DOC_PP1_RVXF_1	703	710	PF00149	0.495
DOC_PP1_RVXF_1	852	859	PF00149	0.479
DOC_PP1_SILK_1	346	351	PF00149	0.332
DOC_PP4_FxxP_1	603	606	PF00568	0.501
DOC_PP4_FxxP_1	749	752	PF00568	0.589
DOC_USP7_MATH_1	285	289	PF00917	0.401
DOC_USP7_MATH_1	597	601	PF00917	0.495
DOC_USP7_MATH_1	617	621	PF00917	0.403
DOC_USP7_UBL2_3	437	441	PF12436	0.453
DOC_USP7_UBL2_3	449	453	PF12436	0.592
DOC_USP7_UBL2_3	477	481	PF12436	0.582
DOC_WW_Pin1_4	728	733	PF00397	0.528
DOC_WW_Pin1_4	837	842	PF00397	0.408
LIG_14-3-3_CanoR_1	136	140	PF00244	0.589
LIG_14-3-3_CanoR_1	235	240	PF00244	0.332
LIG_14-3-3_CanoR_1	401	411	PF00244	0.333
LIG_14-3-3_CanoR_1	511	516	PF00244	0.474
LIG_14-3-3_CanoR_1	668	674	PF00244	0.508
LIG_14-3-3_CanoR_1	793	803	PF00244	0.413
LIG_14-3-3_CanoR_1	82	91	PF00244	0.525
LIG_14-3-3_CanoR_1	832	841	PF00244	0.429
LIG_AP_GAE_1	806	812	PF02883	0.359
LIG_APCC_ABBA_1	272	277	PF00400	0.332
LIG_APCC_ABBAyCdc20_2	271	277	PF00400	0.455
LIG_BIR_III_2	69	73	PF00653	0.627
LIG_BIR_III_4	126	130	PF00653	0.589
LIG_BRCT_BRCA1_1	599	603	PF00533	0.495
LIG_BRCT_BRCA1_1	619	623	PF00533	0.403
LIG_EH1_1	640	648	PF00400	0.495
LIG_FHA_1	17	23	PF00498	0.541
LIG_FHA_1	187	193	PF00498	0.418
LIG_FHA_1	210	216	PF00498	0.350
LIG_FHA_1	344	350	PF00498	0.455
LIG_FHA_1	661	667	PF00498	0.495
LIG_FHA_1	670	676	PF00498	0.508
LIG_FHA_1	710	716	PF00498	0.494
LIG_FHA_1	771	777	PF00498	0.409
LIG_FHA_1	778	784	PF00498	0.382
LIG_FHA_1	825	831	PF00498	0.367
LIG_FHA_1	842	848	PF00498	0.256
LIG_FHA_2	136	142	PF00498	0.589
LIG_FHA_2	311	317	PF00498	0.371
LIG_FHA_2	494	500	PF00498	0.525
LIG_FHA_2	528	534	PF00498	0.463
LIG_FHA_2	552	558	PF00498	0.498
LIG_Integrin_isoDGR_2	784	786	PF01839	0.410
LIG_Integrin_RGD_1	224	226	PF01839	0.332
LIG_LIR_Apic_2	600	606	PF02991	0.495
LIG_LIR_Gen_1	154	165	PF02991	0.471
LIG_LIR_Gen_1	499	508	PF02991	0.429
LIG_LIR_Gen_1	541	551	PF02991	0.555
LIG_LIR_Gen_1	598	609	PF02991	0.495
LIG_LIR_Nem_3	154	160	PF02991	0.494
LIG_LIR_Nem_3	316	321	PF02991	0.436
LIG_LIR_Nem_3	329	335	PF02991	0.426
LIG_LIR_Nem_3	499	505	PF02991	0.433
LIG_LIR_Nem_3	541	546	PF02991	0.603
LIG_LIR_Nem_3	598	604	PF02991	0.495
LIG_PCNA_PIPBox_1	743	752	PF02747	0.526
LIG_PCNA_yPIPBox_3	82	91	PF02747	0.511
LIG_Pex14_2	328	332	PF04695	0.425
LIG_Pex14_2	750	754	PF04695	0.508
LIG_REV1ctd_RIR_1	747	751	PF16727	0.589
LIG_SH2_CRK	502	506	PF00017	0.428
LIG_SH2_CRK	671	675	PF00017	0.549
LIG_SH2_NCK_1	502	506	PF00017	0.428
LIG_SH2_NCK_1	735	739	PF00017	0.575
LIG_SH2_SRC	30	33	PF00017	0.551
LIG_SH2_STAP1	163	167	PF00017	0.409
LIG_SH2_STAP1	671	675	PF00017	0.549
LIG_SH2_STAT3	637	640	PF00017	0.495
LIG_SH2_STAT5	30	33	PF00017	0.551
LIG_SH2_STAT5	321	324	PF00017	0.436
LIG_SH2_STAT5	379	382	PF00017	0.371
LIG_SH2_STAT5	38	41	PF00017	0.551
LIG_SH2_STAT5	653	656	PF00017	0.495
LIG_SH2_STAT5	671	674	PF00017	0.549
LIG_SH2_STAT5	724	727	PF00017	0.515
LIG_SH2_STAT5	803	806	PF00017	0.408
LIG_SH3_3	334	340	PF00018	0.427
LIG_SH3_3	75	81	PF00018	0.557
LIG_SUMO_SIM_anti_2	672	678	PF11976	0.526
LIG_SUMO_SIM_anti_2	712	718	PF11976	0.492
LIG_SUMO_SIM_par_1	111	118	PF11976	0.511
LIG_SUMO_SIM_par_1	200	206	PF11976	0.332
LIG_SUMO_SIM_par_1	671	678	PF11976	0.508
LIG_SUMO_SIM_par_1	711	718	PF11976	0.494
LIG_SUMO_SIM_par_1	773	782	PF11976	0.512
LIG_SxIP_EBH_1	539	550	PF03271	0.467
LIG_TRAF2_1	314	317	PF00917	0.426
LIG_TRAF2_1	341	344	PF00917	0.350
LIG_TRAF2_1	94	97	PF00917	0.589
LIG_TYR_ITIM	500	505	PF00017	0.429
LIG_UBA3_1	112	119	PF00899	0.511
LIG_UBA3_1	139	147	PF00899	0.508
LIG_UBA3_1	348	353	PF00899	0.332
LIG_UBA3_1	763	770	PF00899	0.606
LIG_WW_1	650	653	PF00397	0.495
MOD_CDK_SPK_2	728	733	PF00069	0.589
MOD_CK1_1	194	200	PF00069	0.439
MOD_CK1_1	46	52	PF00069	0.589
MOD_CK1_1	541	547	PF00069	0.607
MOD_CK1_1	840	846	PF00069	0.460
MOD_CK2_1	135	141	PF00069	0.589
MOD_CK2_1	310	316	PF00069	0.361
MOD_CK2_1	338	344	PF00069	0.332
MOD_CK2_1	432	438	PF00069	0.467
MOD_CK2_1	511	517	PF00069	0.479
MOD_CK2_1	527	533	PF00069	0.496
MOD_CK2_1	549	555	PF00069	0.521
MOD_CK2_1	792	798	PF00069	0.359
MOD_Cter_Amidation	130	133	PF01082	0.368
MOD_Cter_Amidation	144	147	PF01082	0.454
MOD_GlcNHglycan	231	234	PF01048	0.448
MOD_GlcNHglycan	433	437	PF01048	0.475
MOD_GlcNHglycan	806	809	PF01048	0.535
MOD_GSK3_1	306	313	PF00069	0.351
MOD_GSK3_1	527	534	PF00069	0.556
MOD_GSK3_1	591	598	PF00069	0.505
MOD_GSK3_1	6	13	PF00069	0.538
MOD_GSK3_1	699	706	PF00069	0.499
MOD_GSK3_1	788	795	PF00069	0.396
MOD_GSK3_1	824	831	PF00069	0.367
MOD_GSK3_1	833	840	PF00069	0.329
MOD_GSK3_1	841	848	PF00069	0.256
MOD_GSK3_1	856	863	PF00069	0.536
MOD_N-GLC_1	824	829	PF02516	0.424
MOD_N-GLC_1	841	846	PF02516	0.236
MOD_N-GLC_2	708	710	PF02516	0.271
MOD_NEK2_1	101	106	PF00069	0.508
MOD_NEK2_1	16	21	PF00069	0.548
MOD_NEK2_1	471	476	PF00069	0.589
MOD_NEK2_1	527	532	PF00069	0.595
MOD_NEK2_1	699	704	PF00069	0.500
MOD_NEK2_1	709	714	PF00069	0.543
MOD_NEK2_1	763	768	PF00069	0.529
MOD_NEK2_1	856	861	PF00069	0.488
MOD_NEK2_2	56	61	PF00069	0.608
MOD_NEK2_2	841	846	PF00069	0.350
MOD_PIKK_1	471	477	PF00454	0.582
MOD_PIKK_1	549	555	PF00454	0.501
MOD_PIKK_1	6	12	PF00454	0.627
MOD_PIKK_1	70	76	PF00454	0.552
MOD_PIKK_1	737	743	PF00454	0.485
MOD_PIKK_1	833	839	PF00454	0.408
MOD_PK_1	788	794	PF00069	0.359
MOD_PKA_1	854	860	PF00069	0.538
MOD_PKA_2	135	141	PF00069	0.589
MOD_PKA_2	194	200	PF00069	0.439
MOD_PKA_2	400	406	PF00069	0.464
MOD_PKA_2	541	547	PF00069	0.477
MOD_PKA_2	595	601	PF00069	0.437
MOD_PKA_2	697	703	PF00069	0.495
MOD_PKA_2	792	798	PF00069	0.408
MOD_PKB_1	667	675	PF00069	0.508
MOD_Plk_1	343	349	PF00069	0.455
MOD_Plk_1	43	49	PF00069	0.589
MOD_Plk_1	788	794	PF00069	0.401
MOD_Plk_1	828	834	PF00069	0.343
MOD_Plk_1	841	847	PF00069	0.307
MOD_Plk_2-3	777	783	PF00069	0.335
MOD_Plk_4	101	107	PF00069	0.495
MOD_Plk_4	135	141	PF00069	0.568
MOD_Plk_4	344	350	PF00069	0.463
MOD_Plk_4	522	528	PF00069	0.559
MOD_Plk_4	535	541	PF00069	0.438
MOD_Plk_4	597	603	PF00069	0.495
MOD_Plk_4	669	675	PF00069	0.508
MOD_Plk_4	709	715	PF00069	0.492
MOD_ProDKin_1	728	734	PF00069	0.528
MOD_ProDKin_1	837	843	PF00069	0.408
MOD_SUMO_for_1	443	446	PF00179	0.567
MOD_SUMO_for_1	459	462	PF00179	0.570
MOD_SUMO_for_1	483	486	PF00179	0.597
MOD_SUMO_for_1	515	518	PF00179	0.421
MOD_SUMO_rev_2	172	176	PF00179	0.441
MOD_SUMO_rev_2	264	273	PF00179	0.404
MOD_SUMO_rev_2	422	428	PF00179	0.307
MOD_SUMO_rev_2	446	454	PF00179	0.570
MOD_SUMO_rev_2	479	483	PF00179	0.524
MOD_SUMO_rev_2	620	629	PF00179	0.499
TRG_DiLeu_BaEn_1	555	560	PF01217	0.500
TRG_DiLeu_BaEn_3	343	349	PF01217	0.350
TRG_DiLeu_BaEn_4	657	663	PF01217	0.551
TRG_DiLeu_BaLyEn_6	297	302	PF01217	0.463
TRG_DiLeu_BaLyEn_6	453	458	PF01217	0.521
TRG_DiLeu_BaLyEn_6	642	647	PF01217	0.495
TRG_DiLeu_LyEn_5	555	560	PF01217	0.500
TRG_ENDOCYTIC_2	157	160	PF00928	0.456
TRG_ENDOCYTIC_2	38	41	PF00928	0.589
TRG_ENDOCYTIC_2	502	505	PF00928	0.432
TRG_ENDOCYTIC_2	671	674	PF00928	0.549
TRG_ER_diArg_1	330	332	PF00400	0.430
TRG_ER_diArg_1	465	468	PF00400	0.474
TRG_ER_diArg_1	585	588	PF00400	0.490
TRG_ER_diArg_1	666	669	PF00400	0.495
TRG_ER_diArg_1	818	820	PF00400	0.332
TRG_NES_CRM1_1	229	240	PF08389	0.463
TRG_NES_CRM1_1	759	771	PF08389	0.557
TRG_NLS_Bipartite_1	132	147	PF00514	0.509
TRG_NLS_MonoExtC_3	142	147	PF00514	0.619
TRG_NLS_MonoExtC_3	416	422	PF00514	0.375
TRG_NLS_MonoExtN_4	416	421	PF00514	0.375
TRG_Pf-PMV_PEXEL_1	350	354	PF00026	0.332
TRG_Pf-PMV_PEXEL_1	383	387	PF00026	0.463
TRG_Pf-PMV_PEXEL_1	419	424	PF00026	0.375
TRG_Pf-PMV_PEXEL_1	513	517	PF00026	0.447

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1P9X7	Leptomonas seymouri	51%	100%
A0A0N1PC62	Leptomonas seymouri	87%	100%
A0A0S4KJV7	Bodo saltans	50%	100%
A0A1X0NJK9	Trypanosomatidae	50%	100%
A0A1X0NRE7	Trypanosomatidae	75%	100%
A0A381MP32	Leishmania infantum	49%	100%
A0A3R7LKM0	Trypanosoma rangeli	74%	100%
A0A3S5H516	Leishmania donovani	49%	100%
A0A3S7X129	Leishmania donovani	54%	100%
A0A422NAZ4	Trypanosoma rangeli	53%	100%
A0R574	Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155)	42%	100%
A4HG34	Leishmania braziliensis	50%	100%
A4HHD8	Leishmania braziliensis	93%	100%
A4I4I4	Leishmania infantum	100%	100%
C9ZJ56	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	50%	100%
C9ZJT4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	69%	100%
E9ACE5	Leishmania major	50%	100%
E9ADY5	Leishmania major	99%	100%
E9AJN3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	49%	100%
E9ALU6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	98%	100%
F4JVJ1	Arabidopsis thaliana	50%	100%
G2K265	Listeria monocytogenes serotype 1/2a (strain 10403S)	50%	100%
O31673	Bacillus subtilis (strain 168)	47%	100%
O34209	Synechococcus elongatus (strain PCC 7942 / FACHB-805)	46%	97%
O67588	Aquifex aeolicus (strain VF5)	49%	86%
O68185	Lactococcus lactis subsp. cremoris (strain MG1363)	50%	100%
O74402	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	49%	100%
O78410	Guillardia theta	41%	100%
O83110	Treponema pallidum (strain Nichols)	45%	99%
O84115	Chlamydia trachomatis (strain D/UW-3/Cx)	44%	100%
O84288	Chlamydia trachomatis (strain D/UW-3/Cx)	44%	100%
O87444	Leptolyngbya boryana	49%	99%
O94641	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	48%	96%
P0A523	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	41%	100%
P0C281	Staphylococcus aureus (strain COL)	48%	100%
P17422	Dichelobacter nodosus	47%	100%
P24428	Mycobacterium leprae (strain TN)	41%	100%
P31539	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	44%	95%
P31540	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	46%	94%
P31541	Solanum lycopersicum	46%	94%
P31542	Solanum lycopersicum	46%	94%
P31543	Trypanosoma brucei brucei	69%	100%
P33416	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	48%	100%
P35100	Pisum sativum	42%	94%
P37571	Bacillus subtilis (strain 168)	44%	100%
P42730	Arabidopsis thaliana	54%	95%
P42762	Arabidopsis thaliana	40%	92%
P44403	Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)	49%	100%
P46523	Brassica napus	44%	99%
P47597	Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37)	46%	100%
P49574	Trieres chinensis	42%	98%
P51332	Porphyra purpurea	45%	100%
P53532	Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025)	48%	100%
P53533	Synechococcus elongatus (strain PCC 7942 / FACHB-805)	48%	99%
P63284	Escherichia coli (strain K12)	49%	100%
P63285	Escherichia coli O157:H7	49%	100%
P63286	Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)	49%	100%
P63287	Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)	49%	100%
P71404	Helicobacter pylori (strain ATCC 700392 / 26695)	45%	100%
P74361	Synechocystis sp. (strain PCC 6803 / Kazusa)	48%	99%
P74459	Synechocystis sp. (strain PCC 6803 / Kazusa)	48%	97%
P75247	Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)	47%	100%
P9WPC8	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	41%	100%
P9WPC9	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	41%	100%
P9WPD0	Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)	49%	100%
P9WPD1	Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)	49%	100%
Q0E3C8	Oryza sativa subsp. japonica	46%	88%
Q1RGR1	Rickettsia bellii (strain RML369-C)	49%	100%
Q1XDF4	Neopyropia yezoensis	45%	100%
Q2FDV8	Staphylococcus aureus (strain USA300)	38%	100%
Q2FJB5	Staphylococcus aureus (strain USA300)	48%	100%
Q2FV74	Staphylococcus aureus (strain NCTC 8325 / PS 47)	38%	100%
Q2G0P5	Staphylococcus aureus (strain NCTC 8325 / PS 47)	48%	100%
Q2QVG9	Oryza sativa subsp. japonica	45%	94%
Q2YSD6	Staphylococcus aureus (strain bovine RF122 / ET3-1)	48%	100%
Q2YWB1	Staphylococcus aureus (strain bovine RF122 / ET3-1)	39%	100%
Q49V34	Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41)	48%	100%
Q4L3I4	Staphylococcus haemolyticus (strain JCSC1435)	49%	100%
Q4UN57	Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)	48%	100%
Q53LY0	Oryza sativa subsp. japonica	44%	93%
Q53N47	Oryza sativa subsp. japonica	46%	94%
Q54316	Brachyspira hyodysenteriae	39%	100%
Q5HD02	Staphylococcus aureus (strain COL)	38%	100%
Q5HHB0	Staphylococcus aureus (strain COL)	55%	100%
Q5HQI5	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	53%	100%
Q5HRM8	Staphylococcus epidermidis (strain ATCC 35984 / RP62A)	47%	100%
Q68XR2	Rickettsia typhi (strain ATCC VR-144 / Wilmington)	46%	100%
Q6F2Y7	Oryza sativa subsp. japonica	54%	95%
Q6G6C6	Staphylococcus aureus (strain MSSA476)	38%	100%
Q6GAV1	Staphylococcus aureus (strain MSSA476)	55%	100%
Q6GBW3	Staphylococcus aureus (strain MSSA476)	48%	100%
Q6GIB2	Staphylococcus aureus (strain MRSA252)	55%	100%
Q6GJE4	Staphylococcus aureus (strain MRSA252)	48%	100%
Q6H795	Oryza sativa subsp. japonica	39%	92%
Q6LMY0	Photobacterium profundum (strain SS9)	48%	100%
Q6MD97	Protochlamydia amoebophila (strain UWE25)	47%	100%
Q6MIV0	Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIMB 9529 / HD100)	49%	100%
Q6N1H2	Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)	50%	99%
Q6NF05	Corynebacterium diphtheriae (strain ATCC 700971 / NCTC 13129 / Biotype gravis)	49%	100%
Q71XF9	Listeria monocytogenes serotype 4b (strain F2365)	51%	100%
Q72AW6	Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough)	50%	100%
Q72IK9	Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)	53%	100%
Q72QU2	Leptospira interrogans serogroup Icterohaemorrhagiae serovar copenhageni (strain Fiocruz L1-130)	48%	100%
Q73BY1	Bacillus cereus (strain ATCC 10987 / NRS 248)	49%	100%
Q73IE4	Wolbachia pipientis wMel	46%	100%
Q73K92	Treponema denticola (strain ATCC 35405 / DSM 14222 / CIP 103919 / JCM 8153 / KCTC 15104)	47%	100%
Q73T66	Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10)	48%	100%
Q74FF1	Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA)	49%	100%
Q74X11	Yersinia pestis	49%	100%
Q75GT3	Oryza sativa subsp. japonica	47%	89%
Q7A3F4	Staphylococcus aureus (strain N315)	38%	100%
Q7A6G6	Staphylococcus aureus (strain N315)	55%	100%
Q7A797	Staphylococcus aureus (strain N315)	48%	100%
Q7AJA9	Chlamydia pneumoniae	44%	100%
Q7AMH5	Salmonella typhi	48%	100%
Q7CEG6	Brucella suis biovar 1 (strain 1330)	50%	99%
Q7CQ01	Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)	48%	100%
Q7CU92	Agrobacterium fabrum (strain C58 / ATCC 33970)	51%	99%
Q7F9I1	Oryza sativa subsp. japonica	46%	94%
Q7M9X4	Wolinella succinogenes (strain ATCC 29543 / DSM 1740 / LMG 7466 / NCTC 11488 / FDC 602W)	47%	100%
Q7MNK1	Vibrio vulnificus (strain YJ016)	47%	100%
Q7MVE7	Porphyromonas gingivalis (strain ATCC BAA-308 / W83)	48%	100%
Q7N788	Photorhabdus laumondii subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01)	49%	100%
Q7NAZ3	Mycoplasma gallisepticum (strain R(low / passage 15 / clone 2))	44%	100%
Q7NFE9	Gloeobacter violaceus (strain ATCC 29082 / PCC 7421)	50%	99%
Q7NWN7	Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757)	50%	100%
Q7U3T3	Parasynechococcus marenigrum (strain WH8102)	43%	96%
Q7U637	Parasynechococcus marenigrum (strain WH8102)	50%	100%
Q7UBW5	Shigella flexneri	48%	100%
Q7UM33	Rhodopirellula baltica (strain DSM 10527 / NCIMB 13988 / SH1)	46%	98%
Q7V2A3	Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / NIES-2087 / MED4)	45%	100%
Q7V8B1	Prochlorococcus marinus (strain MIT 9313)	49%	100%
Q7VBL0	Prochlorococcus marinus (strain SARG / CCMP1375 / SS120)	45%	100%
Q7VJY3	Helicobacter hepaticus (strain ATCC 51449 / 3B1)	46%	100%
Q7VNH1	Haemophilus ducreyi (strain 35000HP / ATCC 700724)	49%	100%
Q7VQF3	Blochmannia floridanus	44%	99%
Q7VYV6	Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251)	49%	100%
Q7W9E6	Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)	49%	100%
Q7WHB6	Bordetella bronchiseptica (strain ATCC BAA-588 / NCTC 13252 / RB50)	49%	100%
Q7WSY8	Propionibacterium freudenreichii subsp. shermanii (strain ATCC 9614 / DSM 4902 / CIP 103027 / NCIMB 8099 / CIRM-BIA1)	48%	100%
Q7X2S8	Meiothermus ruber	51%	100%
Q7XL03	Oryza sativa subsp. japonica	42%	93%
Q81GM5	Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)	50%	100%
Q81TT4	Bacillus anthracis	50%	100%
Q822Q4	Chlamydia caviae (strain ATCC VR-813 / DSM 19441 / 03DC25 / GPIC)	44%	100%
Q826F2	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	48%	99%
Q82EU9	Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)	51%	100%
Q82SD8	Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)	49%	100%
Q831Y7	Enterococcus faecalis (strain ATCC 700802 / V583)	54%	100%
Q83F55	Coxiella burnetii (strain RSA 493 / Nine Mile phase I)	48%	100%
Q83FI1	Tropheryma whipplei (strain Twist)	52%	100%
Q83N78	Tropheryma whipplei (strain TW08/27)	52%	100%
Q87AX8	Xylella fastidiosa (strain Temecula1 / ATCC 700964)	48%	100%
Q87S63	Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633)	48%	100%
Q889C2	Pseudomonas syringae pv. tomato (strain ATCC BAA-871 / DC3000)	50%	100%
Q88Q71	Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440)	50%	100%
Q88VX7	Lactiplantibacillus plantarum (strain ATCC BAA-793 / NCIMB 8826 / WCFS1)	54%	100%
Q898C7	Clostridium tetani (strain Massachusetts / E88)	49%	100%
Q89UL2	Bradyrhizobium diazoefficiens (strain JCM 10833 / BCRC 13528 / IAM 13628 / NBRC 14792 / USDA 110)	50%	99%
Q89YY3	Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)	47%	100%
Q8CJV9	Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)	50%	100%
Q8CPT5	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	53%	100%
Q8CQ88	Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200)	47%	100%
Q8DEV2	Vibrio vulnificus (strain CMCP6)	47%	100%
Q8DG71	Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1)	46%	98%
Q8DJ40	Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1)	50%	100%
Q8DTC7	Streptococcus mutans serotype c (strain ATCC 700610 / UA159)	43%	100%
Q8EBE6	Shewanella oneidensis (strain MR-1)	48%	100%
Q8EU05	Oceanobacillus iheyensis (strain DSM 14371 / CIP 107618 / JCM 11309 / KCTC 3954 / HTE831)	44%	100%
Q8EW28	Malacoplasma penetrans (strain HF-2)	43%	100%
Q8F509	Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)	48%	100%
Q8FM94	Corynebacterium efficiens (strain DSM 44549 / YS-314 / AJ 12310 / JCM 11189 / NBRC 100395)	49%	100%
Q8G4X4	Bifidobacterium longum (strain NCC 2705)	48%	98%
Q8NUR7	Staphylococcus aureus (strain MW2)	38%	100%
Q8NXE7	Staphylococcus aureus (strain MW2)	55%	100%
Q8NXY8	Staphylococcus aureus (strain MW2)	48%	100%
Q8P6A0	Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)	48%	100%
Q8PHQ4	Xanthomonas axonopodis pv. citri (strain 306)	49%	100%
Q8RHQ8	Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355)	48%	100%
Q8VYJ7	Arabidopsis thaliana	46%	90%
Q8XKG8	Clostridium perfringens (strain 13 / Type A)	49%	100%
Q8XZR0	Ralstonia solanacearum (strain GMI1000)	48%	100%
Q8Y570	Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)	50%	100%
Q8YJ91	Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094)	50%	99%
Q8YM56	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	49%	99%
Q8YUL9	Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576)	48%	99%
Q929G7	Listeria innocua serovar 6a (strain ATCC BAA-680 / CLIP 11262)	51%	100%
Q92JK8	Rickettsia conorii (strain ATCC VR-613 / Malish 7)	48%	100%
Q92MK7	Rhizobium meliloti (strain 1021)	50%	100%
Q96UX5	Candida albicans (strain SC5314 / ATCC MYA-2876)	49%	100%
Q97KG0	Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)	51%	100%
Q98G96	Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099)	51%	100%
Q99R88	Staphylococcus aureus (strain Mu50 / ATCC 700699)	38%	100%
Q99VB5	Staphylococcus aureus (strain Mu50 / ATCC 700699)	55%	100%
Q99W78	Staphylococcus aureus (strain Mu50 / ATCC 700699)	48%	100%
Q9A9T4	Caulobacter vibrioides (strain ATCC 19089 / CB15)	49%	100%
Q9CB26	Mycobacterium leprae (strain TN)	48%	100%
Q9CFF3	Lactococcus lactis subsp. lactis (strain IL1403)	50%	100%
Q9CI09	Lactococcus lactis subsp. lactis (strain IL1403)	46%	100%
Q9CKC0	Pasteurella multocida (strain Pm70)	48%	100%
Q9F746	Yersinia enterocolitica	39%	97%
Q9FI56	Arabidopsis thaliana	46%	93%
Q9HVN5	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	50%	100%
Q9I742	Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)	38%	96%
Q9JTP9	Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491)	47%	100%
Q9JYQ8	Neisseria meningitidis serogroup B (strain MC58)	47%	100%
Q9KU18	Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)	48%	100%
Q9LF37	Arabidopsis thaliana	47%	90%
Q9PGC1	Xylella fastidiosa (strain 9a5c)	48%	100%
Q9PI02	Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)	46%	100%
Q9PKA8	Chlamydia muridarum (strain MoPn / Nigg)	44%	100%
Q9PKS5	Chlamydia muridarum (strain MoPn / Nigg)	44%	100%
Q9RA63	Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8)	53%	100%
Q9RVI3	Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / LMG 4051 / NBRC 15346 / NCIMB 9279 / R1 / VKM B-1422)	50%	100%
Q9S5Z2	Lactococcus lactis subsp. cremoris (strain MG1363)	46%	100%
Q9SXJ7	Arabidopsis thaliana	48%	91%
Q9TM05	Cyanidium caldarium	41%	100%
Q9Z6E4	Streptomyces albus G	49%	100%
Q9Z8A6	Chlamydia pneumoniae	39%	100%
Q9ZEA9	Rickettsia prowazekii (strain Madrid E)	48%	100%
Q9ZMH1	Helicobacter pylori (strain J99 / ATCC 700824)	45%	100%
V5AQ73	Trypanosoma cruzi	52%	100%
V5AYJ4	Trypanosoma cruzi	74%	99%