LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, unknown function
Species:
Leishmania donovani
UniProt:
A0A3S7X2C5_LEIDO
TriTrypDb:
LdBPK_291070.1 * , LdCL_290014100 , LDHU3_29.1470
Length:
547

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X2C5
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X2C5

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 174 176 PF00675 0.768
CLV_NRD_NRD_1 19 21 PF00675 0.517
CLV_NRD_NRD_1 270 272 PF00675 0.690
CLV_NRD_NRD_1 323 325 PF00675 0.775
CLV_PCSK_FUR_1 166 170 PF00082 0.609
CLV_PCSK_FUR_1 17 21 PF00082 0.493
CLV_PCSK_FUR_1 268 272 PF00082 0.580
CLV_PCSK_KEX2_1 168 170 PF00082 0.652
CLV_PCSK_KEX2_1 174 176 PF00082 0.662
CLV_PCSK_KEX2_1 188 190 PF00082 0.625
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1IMH2 Leptomonas seymouri 35% 100%
A4HHB0 Leishmania braziliensis 65% 100%
A4I4F6 Leishmania infantum 99% 100%
E9ADV6 Leishmania major 91% 100%
E9ALX4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 84% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS