Hypothetical_protein

Quick info Annotations Localization Phosphorylation Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X286_LEIDO

TriTrypDb:

LdBPK_290320.1 , LdCL_290008000 , LDHU3_29.0450

Length:

123

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	3
GO:0110165	cellular anatomical entity	1	3

Phosphorylation

Promastigote/Amastigote: 43

Expansion

Sequence features

A0A3S7X286

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X286

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	14	16	PF00675	0.542
CLV_NRD_NRD_1	39	41	PF00675	0.558
CLV_NRD_NRD_1	75	77	PF00675	0.554
CLV_PCSK_FUR_1	36	40	PF00082	0.572
CLV_PCSK_KEX2_1	38	40	PF00082	0.563
CLV_PCSK_KEX2_1	4	6	PF00082	0.515
CLV_PCSK_KEX2_1	74	76	PF00082	0.574
CLV_PCSK_PC1ET2_1	4	6	PF00082	0.515
CLV_PCSK_SKI1_1	81	85	PF00082	0.411
DOC_MAPK_MEF2A_6	54	61	PF00069	0.731
DOC_USP7_MATH_1	32	36	PF00917	0.807
DOC_USP7_MATH_1	9	13	PF00917	0.737
DOC_WW_Pin1_4	22	27	PF00397	0.693
DOC_WW_Pin1_4	28	33	PF00397	0.740
DOC_WW_Pin1_4	41	46	PF00397	0.795
DOC_WW_Pin1_4	5	10	PF00397	0.803
LIG_14-3-3_CanoR_1	15	21	PF00244	0.775
LIG_14-3-3_CanoR_1	39	45	PF00244	0.768
LIG_LIR_Nem_3	114	119	PF02991	0.401
LIG_REV1ctd_RIR_1	81	89	PF16727	0.730
LIG_RPA_C_Insects	63	78	PF08784	0.677
LIG_SH3_3	47	53	PF00018	0.667
LIG_TRAF2_1	46	49	PF00917	0.768
MOD_CDC14_SPxK_1	8	11	PF00782	0.659
MOD_CDK_SPxK_1	22	28	PF00069	0.625
MOD_CDK_SPxK_1	5	11	PF00069	0.777
MOD_CK1_1	34	40	PF00069	0.748
MOD_CK1_1	41	47	PF00069	0.528
MOD_CK2_1	57	63	PF00069	0.711
MOD_CMANNOS	108	111	PF00535	0.476
MOD_CMANNOS	92	95	PF00535	0.390
MOD_DYRK1A_RPxSP_1	22	26	PF00069	0.690
MOD_DYRK1A_RPxSP_1	28	32	PF00069	0.688
MOD_GlcNHglycan	22	25	PF01048	0.753
MOD_GSK3_1	115	122	PF00069	0.601
MOD_GSK3_1	16	23	PF00069	0.662
MOD_GSK3_1	28	35	PF00069	0.691
MOD_GSK3_1	40	47	PF00069	0.708
MOD_GSK3_1	5	12	PF00069	0.632
MOD_N-GLC_1	41	46	PF02516	0.771
MOD_N-GLC_1	5	10	PF02516	0.679
MOD_NEK2_1	115	120	PF00069	0.552
MOD_PIKK_1	44	50	PF00454	0.764
MOD_PK_1	16	22	PF00069	0.779
MOD_PKA_1	38	44	PF00069	0.779
MOD_PKA_1	74	80	PF00069	0.711
MOD_PKA_2	38	44	PF00069	0.729
MOD_PKA_2	74	80	PF00069	0.652
MOD_PKB_1	36	44	PF00069	0.774
MOD_ProDKin_1	22	28	PF00069	0.625
MOD_ProDKin_1	41	47	PF00069	0.766
MOD_ProDKin_1	5	11	PF00069	0.777
MOD_SUMO_rev_2	60	69	PF00179	0.574
TRG_ER_diArg_1	36	39	PF00400	0.739
TRG_ER_diArg_1	74	76	PF00400	0.746
TRG_NLS_Bipartite_1	4	19	PF00514	0.651
TRG_NLS_MonoExtN_4	13	19	PF00514	0.689

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I7X6	Leptomonas seymouri	49%	90%
E9AHI1	Leishmania infantum	100%	100%