LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7X247_LEIDO
TriTrypDb:
LdBPK_290440.1 , LdCL_290009200 , LDHU3_29.0590
Length:
564

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. yes yes: 18
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 10
NetGPI no yes: 0, no: 10
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X247
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X247

PDB structure(s): 7ane_ag

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 106 110 PF00656 0.493
CLV_C14_Caspase3-7 420 424 PF00656 0.577
CLV_NRD_NRD_1 24 26 PF00675 0.464
CLV_NRD_NRD_1 296 298 PF00675 0.410
CLV_NRD_NRD_1 368 370 PF00675 0.402
CLV_NRD_NRD_1 395 397 PF00675 0.421
CLV_NRD_NRD_1 51 53 PF00675 0.445
CLV_NRD_NRD_1 520 522 PF00675 0.502
CLV_NRD_NRD_1 532 534 PF00675 0.516
CLV_NRD_NRD_1 537 539 PF00675 0.508
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N0P7G0 Leptomonas seymouri 82% 100%
A0A1X0NZI0 Trypanosomatidae 64% 98%
A0A3R7NNT1 Trypanosoma rangeli 65% 97%
A4HH44 Leishmania braziliensis 93% 100%
A4I497 Leishmania infantum 100% 100%
C9ZKN3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 64% 97%
E9ADP4 Leishmania major 98% 100%
E9AM36 Leishmania mexicana (strain MHOM/GT/2001/U1103) 97% 100%
V5DLE3 Trypanosoma cruzi 64% 97%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS