Ca2+-ATPase N terminal autoinhibitory domain containing protein, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Ca2+-ATPase N terminal autoinhibitory domain containing protein, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X239_LEIDO

TriTrypDb:

LdBPK_290510.1 , LdCL_290009900 , LDHU3_29.0730

Length:

1196

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

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Cellular components
Term	Name	Level	Count
GO:0016020	membrane	2	6
GO:0110165	cellular anatomical entity	1	6

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Expansion

Sequence features

A0A3S7X239

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X239

Function

Could not find GO biological_process term for this entry.

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Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	6
GO:0005515	protein binding	2	6
GO:0005516	calmodulin binding	3	6

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	1024	1028	PF00656	0.633
CLV_C14_Caspase3-7	244	248	PF00656	0.636
CLV_C14_Caspase3-7	291	295	PF00656	0.783
CLV_C14_Caspase3-7	808	812	PF00656	0.482
CLV_NRD_NRD_1	373	375	PF00675	0.761
CLV_NRD_NRD_1	558	560	PF00675	0.444
CLV_NRD_NRD_1	599	601	PF00675	0.576
CLV_NRD_NRD_1	931	933	PF00675	0.670
CLV_NRD_NRD_1	934	936	PF00675	0.668
CLV_PCSK_FUR_1	371	375	PF00082	0.619

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PED6	Leptomonas seymouri	49%	87%
A4HH51	Leishmania braziliensis	74%	99%
A4I4A2	Leishmania infantum	100%	100%
E9ADQ1	Leishmania major	89%	99%
E9AM29	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	99%

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