Serine/threonine-protein phosphatase

Quick info Annotations Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

protein phosphatase 4 catalytic subunit, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X1Y0_LEIDO

TriTrypDb:

LdBPK_282870.1 , LdCL_280033800 , LDHU3_28.3860

Length:

307

Annotations

LeishMANIAdb annotations

A large collection of various protein phosphatases. Very highly expanded in kinetoplastids.

Annotations by Jardim et al.

Phosphatase, Serine/threonine- phosphatase

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	yes	yes: 6
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

Cellular components
Term	Name	Level	Count
GO:0005634	nucleus	5	1
GO:0005654	nucleoplasm	2	1
GO:0005737	cytoplasm	2	1
GO:0043226	organelle	2	1
GO:0043227	membrane-bounded organelle	3	1
GO:0043229	intracellular organelle	3	1
GO:0043231	intracellular membrane-bounded organelle	4	1
GO:0110165	cellular anatomical entity	1	1

Expansion

Sequence features

A0A3S7X1Y0

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X1Y0

Function

Biological processes
Term	Name	Level	Count
GO:0000724	double-strand break repair via homologous recombination	7	1
GO:0000725	recombinational repair	6	1
GO:0006139	nucleobase-containing compound metabolic process	3	1
GO:0006259	DNA metabolic process	4	1
GO:0006281	DNA repair	5	1
GO:0006302	double-strand break repair	6	1
GO:0006310	DNA recombination	5	1
GO:0006725	cellular aromatic compound metabolic process	3	1
GO:0006807	nitrogen compound metabolic process	2	1
GO:0006950	response to stress	2	1
GO:0006974	DNA damage response	4	1
GO:0008152	metabolic process	1	1
GO:0009987	cellular process	1	1
GO:0033554	cellular response to stress	3	1
GO:0034641	cellular nitrogen compound metabolic process	3	1
GO:0043170	macromolecule metabolic process	3	1
GO:0044237	cellular metabolic process	2	1
GO:0044238	primary metabolic process	2	1
GO:0044260	obsolete cellular macromolecule metabolic process	3	1
GO:0046483	heterocycle metabolic process	3	1
GO:0050896	response to stimulus	1	1
GO:0051716	cellular response to stimulus	2	1
GO:0071704	organic substance metabolic process	2	1
GO:0090304	nucleic acid metabolic process	4	1
GO:1901360	organic cyclic compound metabolic process	3	1

Molecular functions
Term	Name	Level	Count
GO:0003824	catalytic activity	1	11
GO:0004721	phosphoprotein phosphatase activity	3	11
GO:0004722	protein serine/threonine phosphatase activity	4	11
GO:0016787	hydrolase activity	2	11
GO:0016788	hydrolase activity, acting on ester bonds	3	11
GO:0016791	phosphatase activity	5	11
GO:0017018	myosin phosphatase activity	5	11
GO:0042578	phosphoric ester hydrolase activity	4	11
GO:0140096	catalytic activity, acting on a protein	2	11

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	129	131	PF00675	0.405
CLV_NRD_NRD_1	179	181	PF00675	0.405
CLV_PCSK_SKI1_1	116	120	PF00082	0.405
CLV_PCSK_SKI1_1	16	20	PF00082	0.478
CLV_PCSK_SKI1_1	244	248	PF00082	0.463
DEG_APCC_DBOX_1	225	233	PF00400	0.517
DOC_MAPK_gen_1	278	286	PF00069	0.582
DOC_MAPK_gen_1	99	108	PF00069	0.405
DOC_MAPK_RevD_3	167	181	PF00069	0.424
DOC_USP7_MATH_1	71	75	PF00917	0.407
DOC_WW_Pin1_4	163	168	PF00397	0.405
LIG_14-3-3_CanoR_1	105	109	PF00244	0.405
LIG_14-3-3_CanoR_1	116	125	PF00244	0.405
LIG_14-3-3_CanoR_1	139	148	PF00244	0.405
LIG_14-3-3_CanoR_1	226	232	PF00244	0.448
LIG_14-3-3_CanoR_1	84	90	PF00244	0.405
LIG_BIR_II_1	1	5	PF00653	0.540
LIG_BRCT_BRCA1_1	73	77	PF00533	0.424
LIG_EH1_1	86	94	PF00400	0.405
LIG_eIF4E_1	58	64	PF01652	0.494
LIG_EVH1_2	302	306	PF00568	0.574
LIG_FAT_LD_1	89	97	PF03623	0.405
LIG_FHA_1	288	294	PF00498	0.638
LIG_FHA_1	71	77	PF00498	0.405
LIG_FHA_1	89	95	PF00498	0.405
LIG_FHA_2	169	175	PF00498	0.424
LIG_LIR_Apic_2	192	198	PF02991	0.405
LIG_LIR_Apic_2	253	258	PF02991	0.415
LIG_LIR_Gen_1	142	153	PF02991	0.405
LIG_LIR_Gen_1	72	82	PF02991	0.405
LIG_LIR_Gen_1	83	94	PF02991	0.405
LIG_LIR_Nem_3	119	125	PF02991	0.405
LIG_LIR_Nem_3	126	132	PF02991	0.405
LIG_LIR_Nem_3	146	150	PF02991	0.405
LIG_LIR_Nem_3	41	47	PF02991	0.462
LIG_LIR_Nem_3	83	89	PF02991	0.396
LIG_NRBOX	91	97	PF00104	0.405
LIG_PCNA_yPIPBox_3	6	16	PF02747	0.472
LIG_PDZ_Class_2	302	307	PF00595	0.586
LIG_SH2_CRK	147	151	PF00017	0.405
LIG_SH2_CRK	44	48	PF00017	0.424
LIG_SH2_NCK_1	44	48	PF00017	0.424
LIG_SH2_SRC	44	47	PF00017	0.486
LIG_SH2_STAP1	125	129	PF00017	0.405
LIG_SH2_STAT5	260	263	PF00017	0.463
LIG_SH2_STAT5	285	288	PF00017	0.602
LIG_SH2_STAT5	75	78	PF00017	0.405
LIG_SH2_STAT5	81	84	PF00017	0.405
LIG_SUMO_SIM_anti_2	104	110	PF11976	0.405
LIG_SUMO_SIM_anti_2	90	97	PF11976	0.405
LIG_SUMO_SIM_par_1	269	275	PF11976	0.575
LIG_SUMO_SIM_par_1	59	65	PF11976	0.508
LIG_TYR_ITSM	40	47	PF00017	0.570
LIG_UBA3_1	60	66	PF00899	0.517
LIG_UBA3_1	92	99	PF00899	0.405
LIG_WW_1	302	305	PF00397	0.584
MOD_CK1_1	88	94	PF00069	0.405
MOD_CK2_1	168	174	PF00069	0.424
MOD_CK2_1	193	199	PF00069	0.478
MOD_CK2_1	266	272	PF00069	0.555
MOD_GlcNHglycan	255	258	PF01048	0.415
MOD_GSK3_1	112	119	PF00069	0.405
MOD_GSK3_1	242	249	PF00069	0.564
MOD_N-GLC_2	250	252	PF02516	0.429
MOD_N-GLC_2	259	261	PF02516	0.429
MOD_NEK2_1	246	251	PF00069	0.564
MOD_NEK2_2	242	247	PF00069	0.464
MOD_PIKK_1	116	122	PF00454	0.405
MOD_PIKK_1	204	210	PF00454	0.517
MOD_PKA_2	104	110	PF00069	0.405
MOD_Plk_1	71	77	PF00069	0.407
MOD_Plk_4	227	233	PF00069	0.456
MOD_Plk_4	242	248	PF00069	0.449
MOD_Plk_4	250	256	PF00069	0.400
MOD_Plk_4	266	272	PF00069	0.428
MOD_Plk_4	39	45	PF00069	0.566
MOD_Plk_4	71	77	PF00069	0.404
MOD_Plk_4	88	94	PF00069	0.329
MOD_ProDKin_1	163	169	PF00069	0.405
MOD_SUMO_rev_2	10	18	PF00179	0.587
TRG_DiLeu_BaEn_1	90	95	PF01217	0.405
TRG_ENDOCYTIC_2	147	150	PF00928	0.424
TRG_ENDOCYTIC_2	243	246	PF00928	0.438
TRG_ENDOCYTIC_2	44	47	PF00928	0.486
TRG_ENDOCYTIC_2	58	61	PF00928	0.414
TRG_ENDOCYTIC_2	75	78	PF00928	0.344
TRG_ENDOCYTIC_2	86	89	PF00928	0.373
TRG_NES_CRM1_1	168	179	PF08389	0.517
TRG_Pf-PMV_PEXEL_1	116	120	PF00026	0.405
TRG_Pf-PMV_PEXEL_1	16	20	PF00026	0.508

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P7S7	Leptomonas seymouri	42%	100%
A0A0N1HSR2	Leptomonas seymouri	38%	82%
A0A0N1I0V3	Leptomonas seymouri	41%	78%
A0A0N1IBK9	Leptomonas seymouri	61%	100%
A0A0N1ILH2	Leptomonas seymouri	30%	72%
A0A0N1P9X9	Leptomonas seymouri	96%	100%
A0A0N1PAV9	Leptomonas seymouri	46%	84%
A0A0N1PCC5	Leptomonas seymouri	56%	99%
A0A0N1PDK9	Leptomonas seymouri	59%	97%
A0A0S4IIW0	Bodo saltans	37%	78%
A0A0S4ILF8	Bodo saltans	60%	100%
A0A0S4J1J1	Bodo saltans	39%	79%
A0A0S4JDD1	Bodo saltans	40%	68%
A0A0S4JJ52	Bodo saltans	46%	81%
A0A0S4JJ96	Bodo saltans	40%	97%
A0A0S4JJH3	Bodo saltans	40%	98%
A0A0S4KGD7	Bodo saltans	61%	100%
A0A0S4KKU2	Bodo saltans	51%	100%
A0A0S4KLF4	Bodo saltans	23%	74%
A0A0S4KM73	Bodo saltans	41%	77%
A0A1X0NK88	Trypanosomatidae	45%	89%
A0A1X0NNN6	Trypanosomatidae	59%	92%
A0A1X0NS37	Trypanosomatidae	84%	100%
A0A1X0NS65	Trypanosomatidae	58%	100%
A0A1X0NUA6	Trypanosomatidae	36%	77%
A0A1X0NYR5	Trypanosomatidae	39%	100%
A0A1X0P6J3	Trypanosomatidae	40%	81%
A0A1X0P7H9	Trypanosomatidae	40%	69%
A0A1X0P7Q5	Trypanosomatidae	36%	79%
A0A1X0P982	Trypanosomatidae	39%	92%
A0A1X0P9R6	Trypanosomatidae	34%	68%
A0A1X0PA67	Trypanosomatidae	42%	100%
A0A1X0PAK9	Trypanosomatidae	40%	100%
A0A1X0PBJ2	Trypanosomatidae	51%	100%
A0A3Q8I8M6	Leishmania donovani	33%	71%
A0A3Q8IFB2	Leishmania donovani	40%	100%
A0A3Q8IH18	Leishmania donovani	60%	100%
A0A3Q8IHY7	Leishmania donovani	43%	100%
A0A3R7KQR6	Trypanosoma rangeli	59%	90%
A0A3R7M399	Trypanosoma rangeli	31%	71%
A0A3R7MBA3	Trypanosoma rangeli	38%	69%
A0A3R7MFZ7	Trypanosoma rangeli	40%	93%
A0A3R7MM48	Trypanosoma rangeli	38%	77%
A0A3R7N275	Trypanosoma rangeli	41%	100%
A0A3R7NP99	Trypanosoma rangeli	50%	100%
A0A3S5H6K2	Leishmania donovani	24%	100%
A0A3S5H6T9	Leishmania donovani	38%	100%
A0A3S5H7Q6	Leishmania donovani	46%	100%
A0A3S7WZ39	Leishmania donovani	58%	100%
A0A3S7X190	Leishmania donovani	41%	100%
A0A3S7X7I6	Leishmania donovani	40%	100%
A0A3S7X7J8	Leishmania donovani	41%	100%
A0A3S7X7K2	Leishmania donovani	39%	100%
A0A3S7X8K6	Leishmania donovani	56%	99%
A0A3S7XAY3	Leishmania donovani	30%	75%
A0A422N8P1	Trypanosoma rangeli	42%	100%
A0A422N9D5	Trypanosoma rangeli	35%	78%
A0A422NKG0	Trypanosoma rangeli	79%	100%
A0A422NPG1	Trypanosoma rangeli	44%	88%
A0A422NYN7	Trypanosoma rangeli	57%	100%
A0A422P483	Trypanosoma rangeli	36%	72%
A0C1E4	Paramecium tetraurelia	61%	100%
A0CCD2	Paramecium tetraurelia	62%	100%
A0CNL9	Paramecium tetraurelia	52%	97%
A0DJ90	Paramecium tetraurelia	64%	100%
A2X2G3	Oryza sativa subsp. indica	61%	100%
A2XN40	Oryza sativa subsp. indica	60%	100%
A2YEB4	Oryza sativa subsp. indica	61%	100%
A3C4N5	Oryza sativa subsp. japonica	60%	98%
A4H6S0	Leishmania braziliensis	27%	73%
A4H7Z3	Leishmania braziliensis	38%	100%
A4HAI7	Leishmania braziliensis	40%	100%
A4HAI8	Leishmania braziliensis	40%	100%
A4HAI9	Leishmania braziliensis	40%	100%
A4HAJ8	Leishmania braziliensis	40%	100%
A4HBE2	Leishmania braziliensis	55%	100%
A4HE75	Leishmania braziliensis	61%	98%
A4HGA9	Leishmania braziliensis	41%	100%
A4HGX0	Leishmania braziliensis	98%	100%
A4HJQ1	Leishmania braziliensis	45%	100%
A4HKU9	Leishmania braziliensis	60%	100%
A4HP65	Leishmania braziliensis	31%	100%
A4HV49	Leishmania infantum	24%	100%
A4HVT0	Leishmania infantum	33%	71%
A4HWC1	Leishmania infantum	38%	100%
A4I1H6	Leishmania infantum	58%	100%
A4I3E3	Leishmania infantum	41%	100%
A4I400	Leishmania infantum	100%	100%
A4I768	Leishmania infantum	46%	100%
A4I8C8	Leishmania infantum	60%	100%
A4I9P2	Leishmania infantum	41%	100%
A4IAJ0	Leishmania infantum	55%	100%
A4IDH0	Leishmania infantum	30%	100%
A6H772	Bos taurus	63%	100%
A8WGP3	Danio rerio	63%	99%
A8XE00	Caenorhabditis briggsae	61%	92%
A9JRC7	Danio rerio	62%	100%
C9ZJZ6	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	59%	95%
C9ZM48	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	72%
C9ZMF3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	45%	89%
C9ZN02	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	38%	94%
C9ZN06	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	42%	100%
C9ZWN3	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	45%	89%
C9ZX13	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	37%	71%
D0A358	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	34%	79%
D0A805	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	39%	100%
D0A970	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	80%	100%
D0AAU4	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	58%	100%
E9AHS8	Leishmania infantum	40%	100%
E9AHS9	Leishmania infantum	40%	100%
E9AHT0	Leishmania infantum	40%	100%
E9AHT1	Leishmania infantum	40%	100%
E9ANT1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	25%	73%
E9APH5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	35%	71%
E9AQ21	Leishmania mexicana (strain MHOM/GT/2001/U1103)	38%	100%
E9ASX3	Leishmania mexicana (strain MHOM/GT/2001/U1103)	29%	100%
E9AXL1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	58%	100%
E9AZN0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	41%	100%
E9B090	Leishmania mexicana (strain MHOM/GT/2001/U1103)	100%	100%
E9B262	Leishmania mexicana (strain MHOM/GT/2001/U1103)	46%	100%
E9B387	Leishmania mexicana (strain MHOM/GT/2001/U1103)	60%	100%
E9B4P8	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
E9B4P9	Leishmania mexicana (strain MHOM/GT/2001/U1103)	39%	100%
E9B4Q0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	39%	100%
E9B4Q1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
E9B4Q6	Leishmania mexicana (strain MHOM/GT/2001/U1103)	40%	100%
E9B5L4	Leishmania mexicana (strain MHOM/GT/2001/U1103)	55%	100%
G5EGK8	Caenorhabditis elegans	59%	97%
O00743	Homo sapiens	62%	100%
O02658	Caenorhabditis elegans	40%	100%
O04856	Nicotiana tabacum	44%	97%
O04857	Nicotiana tabacum	43%	99%
O04858	Nicotiana tabacum	44%	100%
O04860	Nicotiana tabacum	58%	98%
O04951	Arabidopsis thaliana	60%	100%
O15757	Dictyostelium discoideum	42%	96%
O74789	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	55%	88%
O76932	Drosophila melanogaster	62%	100%
O82733	Arabidopsis thaliana	44%	93%
O82734	Arabidopsis thaliana	44%	95%
P0C5D7	Oryza sativa subsp. indica	60%	97%
P11084	Oryctolagus cuniculus	63%	100%
P11493	Sus scrofa	60%	100%
P11611	Oryctolagus cuniculus	59%	99%
P11612	Drosophila melanogaster	41%	98%
P12982	Drosophila melanogaster	44%	100%
P13681	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	43%	94%
P20604	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	60%	99%
P20654	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	44%	95%
P22198	Zea mays	43%	97%
P23594	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	58%	83%
P23595	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	58%	81%
P23635	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	58%	99%
P23636	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	58%	95%
P23696	Drosophila melanogaster	58%	99%
P23733	Trypanosoma brucei brucei	44%	89%
P23734	Trypanosoma brucei brucei	45%	89%
P23777	Brassica napus	44%	100%
P23778	Brassica napus	59%	99%
P23880	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	44%	95%
P30366	Arabidopsis thaliana	44%	97%
P32345	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	56%	100%
P32598	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	45%	98%
P32838	Saccharomyces cerevisiae (strain ATCC 204508 / S288c)	53%	83%
P34350	Caenorhabditis elegans	29%	81%
P36614	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	58%	100%
P36873	Homo sapiens	46%	95%
P36874	Xenopus laevis	46%	95%
P48458	Caenorhabditis elegans	41%	84%
P48459	Caenorhabditis elegans	40%	68%
P48460	Caenorhabditis elegans	33%	68%
P48461	Drosophila melanogaster	44%	94%
P48462	Drosophila melanogaster	45%	93%
P48463	Gallus gallus	58%	99%
P48480	Acetabularia peniculus	45%	96%
P48481	Acetabularia peniculus	45%	96%
P48482	Arabidopsis thaliana	43%	98%
P48483	Arabidopsis thaliana	46%	95%
P48484	Arabidopsis thaliana	45%	96%
P48485	Arabidopsis thaliana	43%	98%
P48486	Arabidopsis thaliana	43%	95%
P48487	Brassica oleracea	43%	97%
P48488	Medicago sativa subsp. varia	46%	96%
P48489	Oryza sativa subsp. japonica	45%	95%
P48490	Phaseolus vulgaris	43%	98%
P48528	Arabidopsis thaliana	64%	100%
P48529	Arabidopsis thaliana	66%	100%
P48577	Acetabularia peniculus	57%	100%
P48578	Arabidopsis thaliana	59%	98%
P48579	Helianthus annuus	62%	100%
P48580	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	63%	94%
P48726	Paramecium tetraurelia	52%	97%
P48727	Caenorhabditis elegans	46%	92%
P49576	Paramecium tetraurelia	65%	100%
P60510	Homo sapiens	63%	100%
P61287	Bos taurus	46%	95%
P61292	Sus scrofa	46%	94%
P62136	Homo sapiens	46%	93%
P62137	Mus musculus	46%	93%
P62138	Rattus norvegicus	46%	93%
P62139	Oryctolagus cuniculus	46%	93%
P62140	Homo sapiens	46%	94%
P62141	Mus musculus	46%	94%
P62142	Rattus norvegicus	46%	94%
P62143	Oryctolagus cuniculus	46%	94%
P62207	Gallus gallus	46%	94%
P62714	Homo sapiens	59%	99%
P62715	Mus musculus	59%	99%
P62716	Rattus norvegicus	59%	99%
P63087	Mus musculus	46%	95%
P63088	Rattus norvegicus	46%	95%
P63330	Mus musculus	58%	99%
P63331	Rattus norvegicus	58%	99%
P67774	Bos taurus	58%	99%
P67775	Homo sapiens	58%	99%
P67776	Sus scrofa	58%	99%
P67777	Oryctolagus cuniculus	58%	99%
P91420	Caenorhabditis elegans	40%	100%
P97470	Mus musculus	63%	100%
Q05547	Drosophila melanogaster	45%	100%
Q06009	Medicago sativa	63%	98%
Q07098	Arabidopsis thaliana	60%	100%
Q07099	Arabidopsis thaliana	61%	100%
Q07100	Arabidopsis thaliana	60%	98%
Q09496	Caenorhabditis elegans	54%	93%
Q0DBD3	Oryza sativa subsp. japonica	61%	100%
Q0E2S4	Oryza sativa subsp. japonica	61%	100%
Q0P594	Bos taurus	59%	99%
Q10298	Schizosaccharomyces pombe (strain 972 / ATCC 24843)	53%	100%
Q10BT5	Oryza sativa subsp. japonica	60%	100%
Q27497	Caenorhabditis elegans	44%	93%
Q27884	Drosophila melanogaster	55%	100%
Q3SWW9	Bos taurus	46%	94%
Q3T0E7	Bos taurus	46%	93%
Q4Q1M5	Leishmania major	29%	100%
Q4Q2C2	Leishmania major	54%	100%
Q4Q3C0	Leishmania major	41%	100%
Q4Q3C5	Leishmania major	40%	100%
Q4Q3C6	Leishmania major	39%	100%
Q4Q3C7	Leishmania major	39%	100%
Q4Q3C8	Leishmania major	39%	100%
Q4Q4W8	Leishmania major	60%	100%
Q4Q5Z8	Leishmania major	46%	100%
Q4Q7Z5	Leishmania major	99%	100%
Q4Q8K1	Leishmania major	41%	100%
Q4Q9W1	Leishmania major	58%	100%
Q4QFG0	Leishmania major	38%	100%
Q4QG03	Leishmania major	34%	100%
Q4QGT8	Leishmania major	24%	100%
Q4WM22	Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)	61%	79%
Q54RD6	Dictyostelium discoideum	53%	98%
Q59KY8	Candida albicans (strain SC5314 / ATCC MYA-2876)	55%	98%
Q5A6B6	Candida albicans (strain SC5314 / ATCC MYA-2876)	54%	74%
Q5BJ92	Rattus norvegicus	62%	100%
Q5I085	Xenopus tropicalis	46%	94%
Q5R6K8	Pongo abelii	63%	100%
Q5R740	Pongo abelii	46%	94%
Q61JR3	Caenorhabditis briggsae	44%	93%
Q627N3	Caenorhabditis briggsae	46%	92%
Q64620	Rattus norvegicus	62%	100%
Q6BFF6	Paramecium tetraurelia	52%	97%
Q6CNT6	Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)	55%	100%
Q6FM81	Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)	56%	99%
Q6GQL2	Xenopus laevis	46%	94%
Q6IP91	Xenopus laevis	62%	100%
Q6NVU2	Xenopus tropicalis	46%	95%
Q6P861	Xenopus tropicalis	62%	100%
Q74ZR2	Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)	57%	99%
Q7SZ10	Xenopus laevis	46%	95%
Q8LSN3	Pisum sativum	58%	100%
Q8MJ46	Canis lupus familiaris	42%	95%
Q8MJ47	Canis lupus familiaris	46%	94%
Q8SRZ0	Encephalitozoon cuniculi (strain GB-M1)	43%	67%
Q8WMS6	Canis lupus familiaris	46%	93%
Q8X178	Blumeria hordei	62%	94%
Q9CQR6	Mus musculus	62%	100%
Q9FN02	Arabidopsis thaliana	38%	74%
Q9HFQ2	Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)	64%	93%
Q9LHE7	Arabidopsis thaliana	57%	100%
Q9M9W3	Arabidopsis thaliana	44%	97%
Q9SX52	Arabidopsis thaliana	57%	100%
Q9U9A3	Dictyostelium discoideum	59%	100%
Q9UW86	Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)	44%	100%
Q9XGH7	Nicotiana tabacum	59%	98%
Q9XTT8	Caenorhabditis elegans	61%	96%
Q9XW79	Caenorhabditis elegans	61%	92%
Q9XZE5	Dictyostelium discoideum	57%	100%
Q9Y0B7	Dictyostelium discoideum	64%	100%
Q9ZSE4	Hevea brasiliensis	60%	100%
V5AUW3	Trypanosoma cruzi	39%	93%
V5B3V2	Trypanosoma cruzi	43%	80%
V5B5K9	Trypanosoma cruzi	58%	92%
V5B8G5	Trypanosoma cruzi	59%	90%
V5BBR3	Trypanosoma cruzi	34%	78%
V5BGM0	Trypanosoma cruzi	38%	77%
V5BKU4	Trypanosoma cruzi	42%	100%
V5BQD7	Trypanosoma cruzi	34%	70%
V5D2G9	Trypanosoma cruzi	43%	87%
V5DAX7	Trypanosoma cruzi	43%	100%
V5DCW3	Trypanosoma cruzi	79%	100%
V5DIG8	Trypanosoma cruzi	36%	71%
V5DMS5	Trypanosoma cruzi	53%	100%