Galactose oxidase, central domain/Kelch motif containing protein, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X1T8_LEIDO

TriTrypDb:

LdBPK_282300.1 , LdCL_280028100 , LDHU3_28.3130

Length:

834

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X1T8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X1T8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	234	238	PF00656	0.482
CLV_C14_Caspase3-7	642	646	PF00656	0.556
CLV_NRD_NRD_1	100	102	PF00675	0.637
CLV_NRD_NRD_1	103	105	PF00675	0.630
CLV_NRD_NRD_1	19	21	PF00675	0.540
CLV_NRD_NRD_1	500	502	PF00675	0.409
CLV_NRD_NRD_1	537	539	PF00675	0.542
CLV_NRD_NRD_1	772	774	PF00675	0.575
CLV_NRD_NRD_1	826	828	PF00675	0.582
CLV_NRD_NRD_1	97	99	PF00675	0.607
CLV_PCSK_FUR_1	98	102	PF00082	0.650
CLV_PCSK_KEX2_1	100	102	PF00082	0.643
CLV_PCSK_KEX2_1	103	105	PF00082	0.637
CLV_PCSK_KEX2_1	18	20	PF00082	0.530
CLV_PCSK_KEX2_1	500	502	PF00082	0.433
CLV_PCSK_KEX2_1	537	539	PF00082	0.723
CLV_PCSK_KEX2_1	762	764	PF00082	0.560
CLV_PCSK_KEX2_1	828	830	PF00082	0.597
CLV_PCSK_KEX2_1	97	99	PF00082	0.611
CLV_PCSK_PC1ET2_1	762	764	PF00082	0.564
CLV_PCSK_PC1ET2_1	828	830	PF00082	0.597
CLV_PCSK_PC7_1	824	830	PF00082	0.586
CLV_PCSK_SKI1_1	259	263	PF00082	0.578
CLV_PCSK_SKI1_1	269	273	PF00082	0.499
CLV_PCSK_SKI1_1	317	321	PF00082	0.498
CLV_PCSK_SKI1_1	44	48	PF00082	0.630
CLV_PCSK_SKI1_1	488	492	PF00082	0.325
CLV_PCSK_SKI1_1	500	504	PF00082	0.532
CLV_PCSK_SKI1_1	545	549	PF00082	0.704
CLV_PCSK_SKI1_1	591	595	PF00082	0.460
CLV_PCSK_SKI1_1	604	608	PF00082	0.469
CLV_PCSK_SKI1_1	714	718	PF00082	0.559
CLV_PCSK_SKI1_1	792	796	PF00082	0.451
CLV_Separin_Metazoa	84	88	PF03568	0.604
DEG_APCC_DBOX_1	316	324	PF00400	0.472
DEG_APCC_DBOX_1	411	419	PF00400	0.465
DEG_APCC_DBOX_1	470	478	PF00400	0.496
DEG_APCC_DBOX_1	590	598	PF00400	0.519
DEG_Nend_UBRbox_3	1	3	PF02207	0.583
DEG_SCF_FBW7_2	176	183	PF00400	0.532
DOC_CDC14_PxL_1	272	280	PF14671	0.520
DOC_CKS1_1	512	517	PF01111	0.573
DOC_CKS1_1	546	551	PF01111	0.563
DOC_CYCLIN_yCln2_LP_2	795	801	PF00134	0.428
DOC_MAPK_FxFP_2	47	50	PF00069	0.647
DOC_MAPK_gen_1	269	277	PF00069	0.547
DOC_MAPK_gen_1	483	492	PF00069	0.454
DOC_MAPK_gen_1	589	597	PF00069	0.530
DOC_MAPK_gen_1	762	769	PF00069	0.570
DOC_MAPK_HePTP_8	482	494	PF00069	0.496
DOC_MAPK_HePTP_8	759	771	PF00069	0.393
DOC_MAPK_MEF2A_6	270	279	PF00069	0.526
DOC_MAPK_MEF2A_6	485	494	PF00069	0.493
DOC_MAPK_MEF2A_6	659	666	PF00069	0.441
DOC_MAPK_MEF2A_6	762	771	PF00069	0.562
DOC_PP1_RVXF_1	200	206	PF00149	0.425
DOC_PP1_RVXF_1	618	625	PF00149	0.543
DOC_PP2B_LxvP_1	220	223	PF13499	0.587
DOC_PP2B_LxvP_1	236	239	PF13499	0.358
DOC_PP2B_LxvP_1	509	512	PF13499	0.643
DOC_PP4_FxxP_1	328	331	PF00568	0.605
DOC_PP4_FxxP_1	47	50	PF00568	0.647
DOC_USP7_MATH_1	271	275	PF00917	0.591
DOC_USP7_MATH_1	28	32	PF00917	0.584
DOC_USP7_MATH_1	373	377	PF00917	0.507
DOC_USP7_MATH_1	398	402	PF00917	0.472
DOC_USP7_MATH_1	587	591	PF00917	0.534
DOC_USP7_MATH_1	605	609	PF00917	0.587
DOC_USP7_MATH_1	670	674	PF00917	0.646
DOC_USP7_MATH_1	677	681	PF00917	0.732
DOC_USP7_MATH_1	781	785	PF00917	0.581
DOC_USP7_MATH_1	93	97	PF00917	0.610
DOC_WW_Pin1_4	134	139	PF00397	0.538
DOC_WW_Pin1_4	153	158	PF00397	0.485
DOC_WW_Pin1_4	176	181	PF00397	0.564
DOC_WW_Pin1_4	376	381	PF00397	0.453
DOC_WW_Pin1_4	384	389	PF00397	0.412
DOC_WW_Pin1_4	511	516	PF00397	0.574
DOC_WW_Pin1_4	545	550	PF00397	0.600
DOC_WW_Pin1_4	555	560	PF00397	0.630
DOC_WW_Pin1_4	63	68	PF00397	0.547
LIG_14-3-3_CanoR_1	103	112	PF00244	0.580
LIG_14-3-3_CanoR_1	202	212	PF00244	0.496
LIG_14-3-3_CanoR_1	213	223	PF00244	0.498
LIG_14-3-3_CanoR_1	362	367	PF00244	0.585
LIG_14-3-3_CanoR_1	381	387	PF00244	0.456
LIG_14-3-3_CanoR_1	447	453	PF00244	0.584
LIG_14-3-3_CanoR_1	501	511	PF00244	0.503
LIG_14-3-3_CanoR_1	52	58	PF00244	0.582
LIG_14-3-3_CanoR_1	538	544	PF00244	0.559
LIG_14-3-3_CanoR_1	648	654	PF00244	0.572
LIG_14-3-3_CanoR_1	751	757	PF00244	0.571
LIG_14-3-3_CanoR_1	780	786	PF00244	0.663
LIG_BIR_III_4	391	395	PF00653	0.472
LIG_BRCT_BRCA1_1	160	164	PF00533	0.516
LIG_BRCT_BRCA1_1	324	328	PF00533	0.618
LIG_deltaCOP1_diTrp_1	428	432	PF00928	0.546
LIG_eIF4E_1	417	423	PF01652	0.359
LIG_EVH1_2	444	448	PF00568	0.348
LIG_FHA_1	215	221	PF00498	0.584
LIG_FHA_1	503	509	PF00498	0.497
LIG_FHA_2	117	123	PF00498	0.603
LIG_FHA_2	232	238	PF00498	0.431
LIG_FHA_2	508	514	PF00498	0.527
LIG_FHA_2	640	646	PF00498	0.566
LIG_FHA_2	674	680	PF00498	0.658
LIG_FHA_2	79	85	PF00498	0.636
LIG_FXI_DFP_1	527	531	PF00024	0.482
LIG_Integrin_isoDGR_2	410	412	PF01839	0.489
LIG_LIR_Apic_2	325	331	PF02991	0.609
LIG_LIR_Gen_1	118	128	PF02991	0.582
LIG_LIR_Gen_1	400	409	PF02991	0.392
LIG_LIR_Gen_1	416	425	PF02991	0.505
LIG_LIR_Gen_1	607	614	PF02991	0.581
LIG_LIR_Gen_1	676	686	PF02991	0.584
LIG_LIR_Gen_1	689	699	PF02991	0.475
LIG_LIR_Gen_1	803	814	PF02991	0.666
LIG_LIR_Gen_1	820	830	PF02991	0.501
LIG_LIR_LC3C_4	289	292	PF02991	0.373
LIG_LIR_Nem_3	3	7	PF02991	0.562
LIG_LIR_Nem_3	365	370	PF02991	0.500
LIG_LIR_Nem_3	400	405	PF02991	0.387
LIG_LIR_Nem_3	416	420	PF02991	0.402
LIG_LIR_Nem_3	484	490	PF02991	0.452
LIG_LIR_Nem_3	607	613	PF02991	0.582
LIG_LIR_Nem_3	618	622	PF02991	0.437
LIG_LIR_Nem_3	676	681	PF02991	0.659
LIG_LIR_Nem_3	689	694	PF02991	0.434
LIG_LIR_Nem_3	803	809	PF02991	0.662
LIG_LIR_Nem_3	820	825	PF02991	0.490
LIG_NRBOX	111	117	PF00104	0.627
LIG_PCNA_yPIPBox_3	751	760	PF02747	0.410
LIG_Pex14_1	487	491	PF04695	0.493
LIG_PTAP_UEV_1	671	676	PF05743	0.561
LIG_REV1ctd_RIR_1	769	778	PF16727	0.543
LIG_SH2_CRK	691	695	PF00017	0.530
LIG_SH2_GRB2like	473	476	PF00017	0.493
LIG_SH2_SRC	417	420	PF00017	0.365
LIG_SH2_STAT3	145	148	PF00017	0.485
LIG_SH2_STAT5	145	148	PF00017	0.485
LIG_SH2_STAT5	243	246	PF00017	0.467
LIG_SH2_STAT5	367	370	PF00017	0.508
LIG_SH2_STAT5	404	407	PF00017	0.420
LIG_SH2_STAT5	417	420	PF00017	0.431
LIG_SH2_STAT5	473	476	PF00017	0.511
LIG_SH3_2	512	517	PF14604	0.583
LIG_SH3_3	135	141	PF00018	0.541
LIG_SH3_3	191	197	PF00018	0.440
LIG_SH3_3	487	493	PF00018	0.493
LIG_SH3_3	509	515	PF00018	0.588
LIG_SH3_3	556	562	PF00018	0.582
LIG_SH3_3	666	672	PF00018	0.634
LIG_SH3_3	700	706	PF00018	0.505
LIG_SUMO_SIM_par_1	273	283	PF11976	0.415
LIG_SUMO_SIM_par_1	478	484	PF11976	0.493
LIG_SUMO_SIM_par_1	507	514	PF11976	0.553
LIG_SUMO_SIM_par_1	724	731	PF11976	0.624
LIG_TRAF2_1	31	34	PF00917	0.651
LIG_TRAF2_1	53	56	PF00917	0.578
LIG_TYR_ITIM	415	420	PF00017	0.377
LIG_TYR_ITIM	46	51	PF00017	0.648
LIG_WRC_WIRS_1	399	404	PF05994	0.427
LIG_WW_3	222	226	PF00397	0.543
LIG_WW_3	444	448	PF00397	0.348
MOD_CDK_SPK_2	376	381	PF00069	0.426
MOD_CDK_SPxK_1	511	517	PF00069	0.515
MOD_CDK_SPxxK_3	545	552	PF00069	0.564
MOD_CK1_1	131	137	PF00069	0.510
MOD_CK1_1	198	204	PF00069	0.464
MOD_CK1_1	246	252	PF00069	0.571
MOD_CK1_1	302	308	PF00069	0.682
MOD_CK1_1	376	382	PF00069	0.510
MOD_CK1_1	61	67	PF00069	0.633
MOD_CK1_1	651	657	PF00069	0.568
MOD_CK1_1	673	679	PF00069	0.650
MOD_CK1_1	68	74	PF00069	0.592
MOD_CK1_1	684	690	PF00069	0.559
MOD_CK1_1	727	733	PF00069	0.622
MOD_CK1_1	754	760	PF00069	0.725
MOD_CK1_1	92	98	PF00069	0.711
MOD_CK2_1	116	122	PF00069	0.568
MOD_CK2_1	28	34	PF00069	0.637
MOD_CK2_1	413	419	PF00069	0.459
MOD_CK2_1	565	571	PF00069	0.681
MOD_CK2_1	78	84	PF00069	0.623
MOD_GlcNHglycan	13	16	PF01048	0.550
MOD_GlcNHglycan	183	187	PF01048	0.530
MOD_GlcNHglycan	205	208	PF01048	0.548
MOD_GlcNHglycan	304	307	PF01048	0.608
MOD_GlcNHglycan	356	359	PF01048	0.517
MOD_GlcNHglycan	375	378	PF01048	0.523
MOD_GlcNHglycan	520	523	PF01048	0.747
MOD_GlcNHglycan	552	555	PF01048	0.675
MOD_GlcNHglycan	607	610	PF01048	0.607
MOD_GlcNHglycan	637	640	PF01048	0.657
MOD_GlcNHglycan	672	675	PF01048	0.566
MOD_GlcNHglycan	70	73	PF01048	0.666
MOD_GlcNHglycan	799	802	PF01048	0.529
MOD_GlcNHglycan	91	94	PF01048	0.545
MOD_GSK3_1	103	110	PF00069	0.505
MOD_GSK3_1	127	134	PF00069	0.517
MOD_GSK3_1	158	165	PF00069	0.459
MOD_GSK3_1	172	179	PF00069	0.521
MOD_GSK3_1	255	262	PF00069	0.674
MOD_GSK3_1	302	309	PF00069	0.640
MOD_GSK3_1	338	345	PF00069	0.522
MOD_GSK3_1	362	369	PF00069	0.422
MOD_GSK3_1	426	433	PF00069	0.438
MOD_GSK3_1	507	514	PF00069	0.527
MOD_GSK3_1	550	557	PF00069	0.596
MOD_GSK3_1	57	64	PF00069	0.687
MOD_GSK3_1	583	590	PF00069	0.588
MOD_GSK3_1	635	642	PF00069	0.612
MOD_GSK3_1	647	654	PF00069	0.701
MOD_GSK3_1	673	680	PF00069	0.647
MOD_GSK3_1	730	737	PF00069	0.628
MOD_GSK3_1	747	754	PF00069	0.429
MOD_GSK3_1	804	811	PF00069	0.389
MOD_GSK3_1	85	92	PF00069	0.754
MOD_N-GLC_1	286	291	PF02516	0.345
MOD_N-GLC_1	302	307	PF02516	0.650
MOD_N-GLC_1	615	620	PF02516	0.478
MOD_N-GLC_1	684	689	PF02516	0.608
MOD_NEK2_1	115	120	PF00069	0.563
MOD_NEK2_1	158	163	PF00069	0.540
MOD_NEK2_1	203	208	PF00069	0.576
MOD_NEK2_1	214	219	PF00069	0.525
MOD_NEK2_1	260	265	PF00069	0.599
MOD_NEK2_1	286	291	PF00069	0.432
MOD_NEK2_1	301	306	PF00069	0.604
MOD_NEK2_1	310	315	PF00069	0.710
MOD_NEK2_1	349	354	PF00069	0.428
MOD_NEK2_1	397	402	PF00069	0.416
MOD_NEK2_1	448	453	PF00069	0.473
MOD_NEK2_1	550	555	PF00069	0.549
MOD_NEK2_1	681	686	PF00069	0.619
MOD_NEK2_1	734	739	PF00069	0.600
MOD_NEK2_1	747	752	PF00069	0.569
MOD_NEK2_2	306	311	PF00069	0.586
MOD_OFUCOSY	229	235	PF10250	0.352
MOD_PIKK_1	246	252	PF00454	0.486
MOD_PIKK_1	625	631	PF00454	0.621
MOD_PIKK_1	718	724	PF00454	0.533
MOD_PKA_1	103	109	PF00069	0.605
MOD_PKA_2	103	109	PF00069	0.533
MOD_PKA_2	51	57	PF00069	0.638
MOD_PKA_2	518	524	PF00069	0.531
MOD_PKA_2	583	589	PF00069	0.563
MOD_PKA_2	647	653	PF00069	0.676
MOD_PKA_2	804	810	PF00069	0.531
MOD_PKA_2	96	102	PF00069	0.604
MOD_PKB_1	101	109	PF00069	0.567
MOD_PKB_1	87	95	PF00069	0.542
MOD_Plk_1	255	261	PF00069	0.683
MOD_Plk_1	286	292	PF00069	0.423
MOD_Plk_1	531	537	PF00069	0.594
MOD_Plk_1	730	736	PF00069	0.629
MOD_Plk_1	741	747	PF00069	0.473
MOD_Plk_1	820	826	PF00069	0.571
MOD_Plk_2-3	413	419	PF00069	0.389
MOD_Plk_4	116	122	PF00069	0.564
MOD_Plk_4	195	201	PF00069	0.441
MOD_Plk_4	286	292	PF00069	0.465
MOD_Plk_4	349	355	PF00069	0.502
MOD_Plk_4	362	368	PF00069	0.483
MOD_Plk_4	413	419	PF00069	0.403
MOD_Plk_4	426	432	PF00069	0.400
MOD_Plk_4	450	456	PF00069	0.447
MOD_Plk_4	724	730	PF00069	0.620
MOD_Plk_4	741	747	PF00069	0.570
MOD_Plk_4	755	761	PF00069	0.564
MOD_Plk_4	781	787	PF00069	0.589
MOD_ProDKin_1	134	140	PF00069	0.534
MOD_ProDKin_1	153	159	PF00069	0.484
MOD_ProDKin_1	176	182	PF00069	0.567
MOD_ProDKin_1	376	382	PF00069	0.447
MOD_ProDKin_1	384	390	PF00069	0.414
MOD_ProDKin_1	511	517	PF00069	0.581
MOD_ProDKin_1	545	551	PF00069	0.603
MOD_ProDKin_1	555	561	PF00069	0.630
MOD_ProDKin_1	63	69	PF00069	0.547
MOD_SUMO_rev_2	32	41	PF00179	0.636
MOD_SUMO_rev_2	600	606	PF00179	0.549
TRG_DiLeu_BaEn_1	457	462	PF01217	0.493
TRG_ENDOCYTIC_2	121	124	PF00928	0.598
TRG_ENDOCYTIC_2	367	370	PF00928	0.508
TRG_ENDOCYTIC_2	417	420	PF00928	0.484
TRG_ENDOCYTIC_2	48	51	PF00928	0.648
TRG_ENDOCYTIC_2	691	694	PF00928	0.516
TRG_ENDOCYTIC_2	9	12	PF00928	0.581
TRG_ER_diArg_1	101	104	PF00400	0.618
TRG_ER_diArg_1	18	20	PF00400	0.588
TRG_ER_diArg_1	22	25	PF00400	0.626
TRG_ER_diArg_1	482	485	PF00400	0.472
TRG_ER_diArg_1	499	501	PF00400	0.613
TRG_ER_diArg_1	827	830	PF00400	0.595
TRG_ER_diArg_1	86	89	PF00400	0.687
TRG_ER_diArg_1	97	100	PF00400	0.629
TRG_NLS_MonoExtC_3	826	831	PF00514	0.592
TRG_NLS_MonoExtN_4	824	831	PF00514	0.588
TRG_Pf-PMV_PEXEL_1	317	322	PF00026	0.470
TRG_Pf-PMV_PEXEL_1	828	832	PF00026	0.600

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P734	Leptomonas seymouri	47%	97%
A0A0S4J0D9	Bodo saltans	24%	100%
A4HGR9	Leishmania braziliensis	80%	100%
E9B036	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
Q4Q850	Leishmania major	91%	100%