Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X1P6_LEIDO

TriTrypDb:

LdBPK_282150.1 , LdCL_280026600 , LDHU3_28.2930

Length:

550

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

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Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A0A3S7X1P6

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X1P6

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	408	412	PF00656	0.688
CLV_NRD_NRD_1	16	18	PF00675	0.594
CLV_NRD_NRD_1	204	206	PF00675	0.557
CLV_NRD_NRD_1	290	292	PF00675	0.516
CLV_PCSK_FUR_1	510	514	PF00082	0.481
CLV_PCSK_KEX2_1	16	18	PF00082	0.594
CLV_PCSK_KEX2_1	204	206	PF00082	0.596
CLV_PCSK_KEX2_1	244	246	PF00082	0.369
CLV_PCSK_KEX2_1	290	292	PF00082	0.516
CLV_PCSK_KEX2_1	318	320	PF00082	0.508

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IL93	Leptomonas seymouri	60%	100%
A0A1X0NQS9	Trypanosomatidae	35%	100%
A0A422NBH7	Trypanosoma rangeli	39%	100%
A4HGQ5	Leishmania braziliensis	76%	100%
A4I3S9	Leishmania infantum	99%	100%
D0A878	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	36%	100%
E9B021	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	100%
Q4Q865	Leishmania major	88%	100%
V5DCT5	Trypanosoma cruzi	37%	100%

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