Uncharacterized protein

Quick info Annotations Localization Phosphorylation Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X1K8_LEIDO

TriTrypDb:

LdBPK_281640.1 , LdCL_280021100 , LDHU3_28.2110

Length:

165

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Phosphorylation

Promastigote/Amastigote: 152

Expansion

Sequence features

A0A3S7X1K8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X1K8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	138	140	PF00675	0.633
CLV_NRD_NRD_1	160	162	PF00675	0.671
CLV_NRD_NRD_1	79	81	PF00675	0.641
CLV_PCSK_KEX2_1	138	140	PF00082	0.633
CLV_PCSK_KEX2_1	159	161	PF00082	0.634
CLV_PCSK_KEX2_1	79	81	PF00082	0.640
CLV_PCSK_SKI1_1	19	23	PF00082	0.573
DOC_MAPK_gen_1	159	165	PF00069	0.626
DOC_USP7_MATH_1	104	108	PF00917	0.535
DOC_USP7_MATH_1	17	21	PF00917	0.677
DOC_USP7_MATH_1	78	82	PF00917	0.655
DOC_USP7_MATH_1	92	96	PF00917	0.497
DOC_USP7_MATH_1	98	102	PF00917	0.555
LIG_14-3-3_CanoR_1	60	69	PF00244	0.632
LIG_14-3-3_CanoR_1	79	84	PF00244	0.510
LIG_BIR_II_1	1	5	PF00653	0.706
LIG_FHA_1	40	46	PF00498	0.557
LIG_LIR_Apic_2	107	111	PF02991	0.544
LIG_SH2_CRK	108	112	PF00017	0.548
LIG_TRAF2_1	119	122	PF00917	0.610
LIG_TRAF2_1	152	155	PF00917	0.625
MOD_CK1_1	15	21	PF00069	0.620
MOD_CK1_1	71	77	PF00069	0.609
MOD_CK2_1	117	123	PF00069	0.599
MOD_CK2_1	149	155	PF00069	0.670
MOD_CK2_1	38	44	PF00069	0.573
MOD_GlcNHglycan	100	103	PF01048	0.545
MOD_GlcNHglycan	15	18	PF01048	0.564
MOD_GlcNHglycan	19	22	PF01048	0.538
MOD_GlcNHglycan	62	65	PF01048	0.696
MOD_GlcNHglycan	70	73	PF01048	0.626
MOD_GlcNHglycan	74	77	PF01048	0.562
MOD_GlcNHglycan	81	84	PF01048	0.462
MOD_GlcNHglycan	87	90	PF01048	0.522
MOD_GlcNHglycan	96	99	PF01048	0.580
MOD_GSK3_1	13	20	PF00069	0.680
MOD_GSK3_1	149	156	PF00069	0.668
MOD_GSK3_1	67	74	PF00069	0.643
MOD_GSK3_1	79	86	PF00069	0.548
MOD_GSK3_1	94	101	PF00069	0.595
MOD_LATS_1	58	64	PF00433	0.629
MOD_N-GLC_1	67	72	PF02516	0.677
MOD_PIKK_1	125	131	PF00454	0.601
MOD_PKA_1	79	85	PF00069	0.588
MOD_PKA_2	78	84	PF00069	0.616
MOD_Plk_1	153	159	PF00069	0.674
MOD_Plk_2-3	149	155	PF00069	0.670
MOD_Plk_2-3	39	45	PF00069	0.641
TRG_ER_diArg_1	137	139	PF00400	0.632
TRG_ER_diArg_1	159	161	PF00400	0.634
TRG_ER_diArg_1	78	80	PF00400	0.637
TRG_Pf-PMV_PEXEL_1	138	142	PF00026	0.636

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1IIA3	Leptomonas seymouri	39%	100%
A4HGK4	Leishmania braziliensis	70%	99%
A4I3N0	Leishmania infantum	100%	100%
E9AZX1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	88%	99%
Q4Q8B4	Leishmania major	84%	96%