LeishMANIAdb
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DNA topoisomerase

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
DNA topoisomerase
Gene product:
DNA topoisomerase III, putative
Species:
Leishmania donovani
UniProt:
A0A3S7X1K1_LEIDO
TriTrypDb:
LdBPK_281900.1 * , LdCL_280024000 , LDHU3_28.2510
Length:
867

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0005634 nucleus 5 1
GO:0005737 cytoplasm 2 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A0A3S7X1K1
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X1K1

Function

Biological processes
Term Name Level Count
GO:0006139 nucleobase-containing compound metabolic process 3 12
GO:0006259 DNA metabolic process 4 12
GO:0006265 DNA topological change 5 12
GO:0006725 cellular aromatic compound metabolic process 3 12
GO:0006807 nitrogen compound metabolic process 2 12
GO:0006996 organelle organization 4 12
GO:0008152 metabolic process 1 12
GO:0009987 cellular process 1 12
GO:0016043 cellular component organization 3 12
GO:0034641 cellular nitrogen compound metabolic process 3 12
GO:0043170 macromolecule metabolic process 3 12
GO:0044237 cellular metabolic process 2 12
GO:0044238 primary metabolic process 2 12
GO:0044260 obsolete cellular macromolecule metabolic process 3 12
GO:0046483 heterocycle metabolic process 3 12
GO:0051276 chromosome organization 5 12
GO:0071103 DNA conformation change 6 12
GO:0071704 organic substance metabolic process 2 12
GO:0071840 cellular component organization or biogenesis 2 12
GO:0090304 nucleic acid metabolic process 4 12
GO:1901360 organic cyclic compound metabolic process 3 12
Molecular functions
Term Name Level Count
GO:0003676 nucleic acid binding 3 12
GO:0003677 DNA binding 4 12
GO:0003824 catalytic activity 1 12
GO:0003916 DNA topoisomerase activity 3 12
GO:0003917 DNA topoisomerase type I (single strand cut, ATP-independent) activity 4 12
GO:0005488 binding 1 12
GO:0016853 isomerase activity 2 12
GO:0097159 organic cyclic compound binding 2 12
GO:0140097 catalytic activity, acting on DNA 3 12
GO:0140640 catalytic activity, acting on a nucleic acid 2 12
GO:1901363 heterocyclic compound binding 2 12

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 737 741 PF00656 0.387
CLV_NRD_NRD_1 129 131 PF00675 0.235
CLV_NRD_NRD_1 29 31 PF00675 0.277
CLV_NRD_NRD_1 805 807 PF00675 0.397
CLV_NRD_NRD_1 835 837 PF00675 0.522
CLV_PCSK_KEX2_1 129 131 PF00082 0.221
CLV_PCSK_KEX2_1 29 31 PF00082 0.235
CLV_PCSK_KEX2_1 835 837 PF00082 0.495
CLV_PCSK_SKI1_1 261 265 PF00082 0.300
CLV_PCSK_SKI1_1 272 276 PF00082 0.252
CLV_PCSK_SKI1_1 3 7 PF00082 0.260
CLV_PCSK_SKI1_1 416 420 PF00082 0.345
CLV_PCSK_SKI1_1 524 528 PF00082 0.390
CLV_PCSK_SKI1_1 585 589 PF00082 0.305
CLV_PCSK_SKI1_1 610 614 PF00082 0.340
CLV_PCSK_SKI1_1 620 624 PF00082 0.314
CLV_PCSK_SKI1_1 800 804 PF00082 0.504
DEG_APCC_DBOX_1 260 268 PF00400 0.390
DEG_APCC_DBOX_1 565 573 PF00400 0.339
DEG_SCF_FBW7_1 379 386 PF00400 0.390
DEG_SPOP_SBC_1 52 56 PF00917 0.421
DOC_ANK_TNKS_1 302 309 PF00023 0.266
DOC_CKS1_1 380 385 PF01111 0.245
DOC_MAPK_gen_1 269 279 PF00069 0.249
DOC_MAPK_gen_1 29 36 PF00069 0.413
DOC_MAPK_gen_1 416 426 PF00069 0.245
DOC_MAPK_gen_1 524 533 PF00069 0.374
DOC_MAPK_gen_1 585 593 PF00069 0.367
DOC_MAPK_HePTP_8 169 181 PF00069 0.260
DOC_MAPK_JIP1_4 527 533 PF00069 0.376
DOC_MAPK_MEF2A_6 172 181 PF00069 0.245
DOC_MAPK_MEF2A_6 272 281 PF00069 0.246
DOC_MAPK_MEF2A_6 419 426 PF00069 0.246
DOC_MAPK_MEF2A_6 527 535 PF00069 0.360
DOC_MAPK_MEF2A_6 540 548 PF00069 0.194
DOC_MAPK_MEF2A_6 763 770 PF00069 0.423
DOC_MAPK_NFAT4_5 172 180 PF00069 0.245
DOC_MAPK_RevD_3 792 807 PF00069 0.358
DOC_PP2B_LxvP_1 546 549 PF13499 0.245
DOC_PP4_FxxP_1 641 644 PF00568 0.370
DOC_PP4_FxxP_1 655 658 PF00568 0.249
DOC_PP4_FxxP_1 80 83 PF00568 0.421
DOC_PP4_FxxP_1 815 818 PF00568 0.336
DOC_USP7_MATH_1 236 240 PF00917 0.382
DOC_USP7_MATH_1 383 387 PF00917 0.390
DOC_USP7_MATH_1 651 655 PF00917 0.341
DOC_WW_Pin1_4 207 212 PF00397 0.245
DOC_WW_Pin1_4 379 384 PF00397 0.245
DOC_WW_Pin1_4 385 390 PF00397 0.245
DOC_WW_Pin1_4 409 414 PF00397 0.245
DOC_WW_Pin1_4 43 48 PF00397 0.507
DOC_WW_Pin1_4 818 823 PF00397 0.383
LIG_14-3-3_CanoR_1 322 328 PF00244 0.390
LIG_14-3-3_CanoR_1 515 521 PF00244 0.390
LIG_14-3-3_CanoR_1 776 785 PF00244 0.440
LIG_Actin_WH2_2 162 180 PF00022 0.260
LIG_APCC_ABBAyCdc20_2 251 257 PF00400 0.245
LIG_BRCT_BRCA1_1 60 64 PF00533 0.435
LIG_BRCT_BRCA1_1 745 749 PF00533 0.412
LIG_Clathr_ClatBox_1 244 248 PF01394 0.281
LIG_deltaCOP1_diTrp_1 248 255 PF00928 0.245
LIG_deltaCOP1_diTrp_1 395 400 PF00928 0.310
LIG_FHA_1 104 110 PF00498 0.461
LIG_FHA_1 208 214 PF00498 0.245
LIG_FHA_1 29 35 PF00498 0.514
LIG_FHA_1 292 298 PF00498 0.248
LIG_FHA_1 357 363 PF00498 0.390
LIG_FHA_1 421 427 PF00498 0.271
LIG_FHA_1 54 60 PF00498 0.410
LIG_FHA_1 638 644 PF00498 0.299
LIG_FHA_1 730 736 PF00498 0.314
LIG_FHA_1 79 85 PF00498 0.474
LIG_FHA_2 145 151 PF00498 0.460
LIG_FHA_2 484 490 PF00498 0.245
LIG_FHA_2 72 78 PF00498 0.421
LIG_FHA_2 778 784 PF00498 0.393
LIG_FHA_2 83 89 PF00498 0.421
LIG_GBD_Chelix_1 14 22 PF00786 0.210
LIG_LIR_Apic_2 638 644 PF02991 0.290
LIG_LIR_Apic_2 653 658 PF02991 0.333
LIG_LIR_Apic_2 77 83 PF02991 0.421
LIG_LIR_Gen_1 149 158 PF02991 0.364
LIG_LIR_Gen_1 440 450 PF02991 0.270
LIG_LIR_Gen_1 514 525 PF02991 0.260
LIG_LIR_Gen_1 578 587 PF02991 0.438
LIG_LIR_Gen_1 592 602 PF02991 0.340
LIG_LIR_Gen_1 660 669 PF02991 0.277
LIG_LIR_Nem_3 149 155 PF02991 0.320
LIG_LIR_Nem_3 229 235 PF02991 0.245
LIG_LIR_Nem_3 352 357 PF02991 0.319
LIG_LIR_Nem_3 395 400 PF02991 0.294
LIG_LIR_Nem_3 440 446 PF02991 0.276
LIG_LIR_Nem_3 46 52 PF02991 0.484
LIG_LIR_Nem_3 514 520 PF02991 0.309
LIG_LIR_Nem_3 578 584 PF02991 0.310
LIG_LIR_Nem_3 592 597 PF02991 0.356
LIG_LIR_Nem_3 601 605 PF02991 0.360
LIG_LIR_Nem_3 660 665 PF02991 0.309
LIG_LYPXL_SIV_4 635 643 PF13949 0.333
LIG_MYND_1 818 822 PF01753 0.383
LIG_NRP_CendR_1 866 867 PF00754 0.588
LIG_Pex14_2 139 143 PF04695 0.477
LIG_Pex14_2 580 584 PF04695 0.275
LIG_Pex14_2 60 64 PF04695 0.410
LIG_PTB_Apo_2 681 688 PF02174 0.317
LIG_REV1ctd_RIR_1 578 587 PF16727 0.290
LIG_SH2_CRK 517 521 PF00017 0.260
LIG_SH2_CRK 682 686 PF00017 0.322
LIG_SH2_NCK_1 682 686 PF00017 0.322
LIG_SH2_STAP1 575 579 PF00017 0.319
LIG_SH2_STAT5 190 193 PF00017 0.299
LIG_SH2_STAT5 311 314 PF00017 0.315
LIG_SH2_STAT5 320 323 PF00017 0.274
LIG_SH2_STAT5 324 327 PF00017 0.269
LIG_SH2_STAT5 357 360 PF00017 0.279
LIG_SH2_STAT5 39 42 PF00017 0.427
LIG_SH2_STAT5 402 405 PF00017 0.245
LIG_SH2_STAT5 484 487 PF00017 0.248
LIG_SH2_STAT5 49 52 PF00017 0.441
LIG_SH2_STAT5 517 520 PF00017 0.264
LIG_SH2_STAT5 558 561 PF00017 0.274
LIG_SH2_STAT5 621 624 PF00017 0.333
LIG_SH2_STAT5 633 636 PF00017 0.389
LIG_SH2_STAT5 734 737 PF00017 0.298
LIG_SH2_STAT5 778 781 PF00017 0.369
LIG_SH3_1 673 679 PF00018 0.287
LIG_SH3_2 380 385 PF14604 0.245
LIG_SH3_3 377 383 PF00018 0.245
LIG_SH3_3 435 441 PF00018 0.260
LIG_SH3_3 522 528 PF00018 0.304
LIG_SH3_3 673 679 PF00018 0.287
LIG_SUMO_SIM_anti_2 294 299 PF11976 0.245
LIG_SUMO_SIM_par_1 4 10 PF11976 0.258
LIG_TRAF2_1 147 150 PF00917 0.356
LIG_TRAF2_1 74 77 PF00917 0.421
LIG_TRAF2_1 780 783 PF00917 0.356
LIG_UBA3_1 263 272 PF00899 0.329
LIG_UBA3_1 430 436 PF00899 0.451
LIG_UBA3_1 490 496 PF00899 0.245
LIG_UBA3_1 535 540 PF00899 0.279
LIG_WRC_WIRS_1 652 657 PF05994 0.364
LIG_WW_1 481 484 PF00397 0.279
MOD_CDK_SPxK_1 379 385 PF00069 0.245
MOD_CDK_SPxxK_3 409 416 PF00069 0.245
MOD_CK1_1 144 150 PF00069 0.457
MOD_CK1_1 17 23 PF00069 0.529
MOD_CK1_1 201 207 PF00069 0.260
MOD_CK1_1 28 34 PF00069 0.488
MOD_CK1_1 282 288 PF00069 0.311
MOD_CK1_1 390 396 PF00069 0.186
MOD_CK1_1 483 489 PF00069 0.394
MOD_CK1_1 504 510 PF00069 0.375
MOD_CK1_1 603 609 PF00069 0.385
MOD_CK1_1 729 735 PF00069 0.322
MOD_CK2_1 10 16 PF00069 0.410
MOD_CK2_1 144 150 PF00069 0.462
MOD_CK2_1 311 317 PF00069 0.390
MOD_CK2_1 385 391 PF00069 0.304
MOD_CK2_1 550 556 PF00069 0.245
MOD_CK2_1 71 77 PF00069 0.421
MOD_CK2_1 777 783 PF00069 0.396
MOD_DYRK1A_RPxSP_1 385 389 PF00069 0.390
MOD_GlcNHglycan 143 146 PF01048 0.210
MOD_GlcNHglycan 269 272 PF01048 0.318
MOD_GlcNHglycan 385 388 PF01048 0.284
MOD_GlcNHglycan 391 395 PF01048 0.236
MOD_GlcNHglycan 433 436 PF01048 0.316
MOD_GlcNHglycan 602 605 PF01048 0.367
MOD_GlcNHglycan 88 92 PF01048 0.216
MOD_GSK3_1 10 17 PF00069 0.416
MOD_GSK3_1 163 170 PF00069 0.258
MOD_GSK3_1 181 188 PF00069 0.322
MOD_GSK3_1 287 294 PF00069 0.255
MOD_GSK3_1 323 330 PF00069 0.302
MOD_GSK3_1 379 386 PF00069 0.390
MOD_GSK3_1 463 470 PF00069 0.451
MOD_GSK3_1 476 483 PF00069 0.326
MOD_GSK3_1 58 65 PF00069 0.412
MOD_GSK3_1 705 712 PF00069 0.651
MOD_GSK3_1 722 729 PF00069 0.274
MOD_GSK3_1 739 746 PF00069 0.476
MOD_GSK3_1 78 85 PF00069 0.324
MOD_GSK3_1 87 94 PF00069 0.493
MOD_N-GLC_1 163 168 PF02516 0.258
MOD_N-GLC_1 23 28 PF02516 0.301
MOD_N-GLC_1 277 282 PF02516 0.310
MOD_N-GLC_1 349 354 PF02516 0.337
MOD_N-GLC_2 119 121 PF02516 0.210
MOD_N-GLC_2 762 764 PF02516 0.309
MOD_NEK2_1 14 19 PF00069 0.507
MOD_NEK2_1 198 203 PF00069 0.295
MOD_NEK2_1 255 260 PF00069 0.357
MOD_NEK2_1 407 412 PF00069 0.245
MOD_NEK2_1 417 422 PF00069 0.245
MOD_NEK2_1 431 436 PF00069 0.245
MOD_NEK2_1 50 55 PF00069 0.416
MOD_NEK2_1 550 555 PF00069 0.269
MOD_NEK2_1 598 603 PF00069 0.318
MOD_NEK2_2 651 656 PF00069 0.285
MOD_OFUCOSY 721 726 PF10250 0.330
MOD_OFUCOSY 736 743 PF10250 0.333
MOD_PIKK_1 476 482 PF00454 0.261
MOD_PIKK_1 63 69 PF00454 0.514
MOD_PKA_2 265 271 PF00069 0.413
MOD_PKA_2 28 34 PF00069 0.514
MOD_PKA_2 287 293 PF00069 0.259
MOD_Plk_1 198 204 PF00069 0.295
MOD_Plk_1 255 261 PF00069 0.390
MOD_Plk_1 277 283 PF00069 0.279
MOD_Plk_1 330 336 PF00069 0.245
MOD_Plk_1 349 355 PF00069 0.266
MOD_Plk_1 501 507 PF00069 0.245
MOD_Plk_1 637 643 PF00069 0.290
MOD_Plk_1 726 732 PF00069 0.445
MOD_Plk_2-3 10 16 PF00069 0.413
MOD_Plk_4 103 109 PF00069 0.421
MOD_Plk_4 134 140 PF00069 0.437
MOD_Plk_4 17 23 PF00069 0.559
MOD_Plk_4 198 204 PF00069 0.260
MOD_Plk_4 272 278 PF00069 0.280
MOD_Plk_4 349 355 PF00069 0.293
MOD_Plk_4 480 486 PF00069 0.390
MOD_Plk_4 798 804 PF00069 0.517
MOD_ProDKin_1 207 213 PF00069 0.245
MOD_ProDKin_1 379 385 PF00069 0.245
MOD_ProDKin_1 409 415 PF00069 0.245
MOD_ProDKin_1 43 49 PF00069 0.507
MOD_ProDKin_1 818 824 PF00069 0.380
MOD_SUMO_for_1 226 229 PF00179 0.245
MOD_SUMO_rev_2 174 179 PF00179 0.251
MOD_SUMO_rev_2 793 802 PF00179 0.337
TRG_DiLeu_BaLyEn_6 258 263 PF01217 0.260
TRG_DiLeu_BaLyEn_6 413 418 PF01217 0.310
TRG_ENDOCYTIC_2 195 198 PF00928 0.279
TRG_ENDOCYTIC_2 49 52 PF00928 0.449
TRG_ENDOCYTIC_2 517 520 PF00928 0.309
TRG_ENDOCYTIC_2 636 639 PF00928 0.313
TRG_ENDOCYTIC_2 652 655 PF00928 0.443
TRG_ER_diArg_1 128 130 PF00400 0.435
TRG_ER_diArg_1 251 254 PF00400 0.246
TRG_ER_diArg_1 286 289 PF00400 0.260
TRG_ER_diArg_1 29 32 PF00400 0.480
TRG_ER_diArg_1 551 554 PF00400 0.390
TRG_ER_diArg_1 827 830 PF00400 0.426
TRG_ER_diArg_1 834 836 PF00400 0.469
TRG_Pf-PMV_PEXEL_1 261 265 PF00026 0.248
TRG_Pf-PMV_PEXEL_1 95 100 PF00026 0.145

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0L0P6P7 Candida auris 35% 100%
A0A0N1I0P1 Leptomonas seymouri 88% 100%
A0A0N1PAL1 Leptomonas seymouri 35% 90%
A0A0S4J933 Bodo saltans 67% 99%
A0A0S4JI21 Bodo saltans 31% 89%
A0A1X0NSK9 Trypanosomatidae 74% 100%
A0A1X0P3I0 Trypanosomatidae 33% 93%
A0A3R7KDV1 Trypanosoma rangeli 33% 94%
A0A3S7WW83 Leishmania donovani 23% 100%
A0A3S7XB89 Leishmania donovani 33% 92%
A0A422NYW0 Trypanosoma rangeli 73% 100%
A0R5D9 Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) 25% 93%
A4HGN1 Leishmania braziliensis 92% 100%
A4HPI6 Leishmania braziliensis 32% 100%
A4I3Q5 Leishmania infantum 99% 100%
A4IDA8 Leishmania infantum 33% 100%
C7J0A2 Oryza sativa subsp. japonica 35% 93%
D0A8A5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 72% 100%
D0A8E9 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 32% 94%
E9AT98 Leishmania mexicana (strain MHOM/GT/2001/U1103) 33% 100%
E9AUX9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 23% 100%
E9AZZ7 Leishmania mexicana (strain MHOM/GT/2001/U1103) 98% 100%
F4ISQ7 Arabidopsis thaliana 48% 100%
O27661 Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) 27% 100%
O28469 Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) 28% 100%
O34204 Fervidobacterium islandicum 23% 100%
O51934 Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) 22% 79%
O58356 Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3) 25% 100%
O60126 Schizosaccharomyces pombe (strain 972 / ATCC 24843) 35% 100%
O61660 Caenorhabditis elegans 36% 100%
O67037 Aquifex aeolicus (strain VF5) 24% 76%
O69548 Mycobacterium leprae (strain TN) 26% 92%
O70157 Mus musculus 36% 86%
O83409 Treponema pallidum (strain Nichols) 21% 100%
O95985 Homo sapiens 49% 100%
O96651 Drosophila melanogaster 45% 99%
P0A621 Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) 25% 93%
P0C2W6 Staphylococcus aureus (strain bovine RF122 / ET3-1) 24% 100%
P13099 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 34% 100%
P14294 Escherichia coli (strain K12) 23% 100%
P34185 Synechococcus elongatus (strain PCC 7942 / FACHB-805) 24% 98%
P40687 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 23% 100%
P43704 Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) 24% 100%
P46799 Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) 23% 100%
P47368 Mycoplasma genitalium (strain ATCC 33530 / DSM 19775 / NCTC 10195 / G37) 22% 100%
P78032 Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1) 24% 100%
P9WG48 Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) 25% 93%
P9WG49 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 25% 93%
Q08582 Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) 22% 69%
Q0J0S6 Oryza sativa subsp. japonica 47% 100%
Q13472 Homo sapiens 35% 87%
Q2FEN5 Staphylococcus aureus (strain USA300) 24% 100%
Q2FW03 Staphylococcus aureus (strain NCTC 8325 / PS 47) 24% 100%
Q49ZH2 Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41) 22% 100%
Q4L8B8 Staphylococcus haemolyticus (strain JCSC1435) 23% 100%
Q4Q199 Leishmania major 33% 100%
Q4Q888 Leishmania major 98% 100%
Q4QCK3 Leishmania major 23% 100%
Q59046 Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) 25% 100%
Q5HDV4 Staphylococcus aureus (strain COL) 24% 100%
Q5HLZ4 Staphylococcus epidermidis (strain ATCC 35984 / RP62A) 22% 100%
Q5HPU2 Staphylococcus epidermidis (strain ATCC 35984 / RP62A) 24% 100%
Q5WAX6 Alkalihalobacillus clausii (strain KSM-K16) 23% 100%
Q6G767 Staphylococcus aureus (strain MSSA476) 24% 100%
Q6GEH9 Staphylococcus aureus (strain MRSA252) 24% 100%
Q7A075 Staphylococcus aureus (strain MW2) 24% 100%
Q7A455 Staphylococcus aureus (strain N315) 24% 100%
Q8CRF7 Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) 22% 100%
Q8CSU3 Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) 24% 100%
Q8T2T7 Dictyostelium discoideum 36% 100%
Q8Z6F5 Salmonella typhi 23% 100%
Q8ZXT5 Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2) 24% 71%
Q99S17 Staphylococcus aureus (strain Mu50 / ATCC 700699) 24% 100%
Q9CP53 Pasteurella multocida (strain Pm70) 23% 100%
Q9HM08 Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) 29% 100%
Q9KA23 Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) 25% 100%
Q9KQF5 Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) 23% 100%
Q9LVP1 Arabidopsis thaliana 36% 94%
Q9NG98 Drosophila melanogaster 36% 69%
Q9PHK2 Xylella fastidiosa (strain 9a5c) 22% 100%
Q9UYS8 Pyrococcus abyssi (strain GE5 / Orsay) 26% 100%
Q9UZ86 Pyrococcus abyssi (strain GE5 / Orsay) 22% 71%
Q9YB01 Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1) 26% 100%
Q9Z321 Mus musculus 49% 100%
V5AV88 Trypanosoma cruzi 74% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS