LeishMANIAdb
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Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7X1C6_LEIDO
TriTrypDb:
LdBPK_281140.1 , LdCL_280016000 , LDHU3_28.1390
Length:
408

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 6
NetGPI no yes: 0, no: 6
Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X1C6
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X1C6

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 195 197 PF00675 0.538
CLV_NRD_NRD_1 249 251 PF00675 0.395
CLV_NRD_NRD_1 332 334 PF00675 0.365
CLV_NRD_NRD_1 82 84 PF00675 0.586
CLV_PCSK_KEX2_1 195 197 PF00082 0.538
CLV_PCSK_KEX2_1 249 251 PF00082 0.395
CLV_PCSK_KEX2_1 331 333 PF00082 0.608
DEG_APCC_DBOX_1 180 188 PF00400 0.374
DEG_APCC_DBOX_1 82 90 PF00400 0.424
DEG_SPOP_SBC_1 134 138 PF00917 0.613
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Homologs

ProteinTaxonomySequence identityCoverage
A0A1X0NYD6 Trypanosomatidae 34% 83%
A4HGE9 Leishmania braziliensis 70% 100%
A4I3I0 Leishmania infantum 98% 100%
E9AZS2 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 100%
Q4Q8G2 Leishmania major 89% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS