Oxidoreductase-like protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

oxidoreductase-like protein

Species:

Leishmania donovani

UniProt:

A0A3S7X1C4_LEIDO

TriTrypDb:

LdBPK_281030.1 , LdCL_280014900 , LDHU3_28.1240

Length:

973

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 10
NetGPI	no	yes: 0, no: 10

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Cellular components
Term	Name	Level	Count
GO:0005654	nucleoplasm	2	1
GO:0005737	cytoplasm	2	1
GO:0110165	cellular anatomical entity	1	1

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Expansion

Sequence features

A0A3S7X1C4

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X1C4

Putative motif mimicry

Show entries


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	191	195	PF00656	0.692
CLV_C14_Caspase3-7	287	291	PF00656	0.711
CLV_C14_Caspase3-7	466	470	PF00656	0.673
CLV_C14_Caspase3-7	942	946	PF00656	0.366
CLV_NRD_NRD_1	117	119	PF00675	0.546
CLV_NRD_NRD_1	131	133	PF00675	0.568
CLV_NRD_NRD_1	495	497	PF00675	0.394
CLV_NRD_NRD_1	9	11	PF00675	0.791
CLV_NRD_NRD_1	931	933	PF00675	0.459
CLV_NRD_NRD_1	96	98	PF00675	0.576

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P863	Leptomonas seymouri	69%	97%
A0A1X0NZS2	Trypanosomatidae	55%	100%
A0A3R7KME7	Trypanosoma rangeli	52%	100%
A4HGD8	Leishmania braziliensis	81%	99%
A4I3H1	Leishmania infantum	100%	100%
D0A7W5	Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972)	49%	100%
E9AZR0	Leishmania mexicana (strain MHOM/GT/2001/U1103)	90%	98%
Q4Q8H3	Leishmania major	93%	100%
V5BG64	Trypanosoma cruzi	55%	100%

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