LeishMANIAdb
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RAD50 DNA repair-like protein

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
RAD50 DNA repair-like protein
Gene product:
RAD50 DNA repair-like protein
Species:
Leishmania donovani
UniProt:
A0A3S7X1A7_LEIDO
TriTrypDb:
LdBPK_280560.1 , LdCL_280010300 , LDHU3_28.0680
Length:
1360

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 11
NetGPI no yes: 0, no: 11
Cellular components
Term Name Level Count
GO:0030870 Mre11 complex 3 10
GO:0032991 protein-containing complex 1 10
GO:0140513 nuclear protein-containing complex 2 10
GO:0000228 nuclear chromosome 6 1
GO:0000793 condensed chromosome 6 1
GO:0000794 condensed nuclear chromosome 7 1
GO:0005634 nucleus 5 1
GO:0005694 chromosome 5 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043228 non-membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0043232 intracellular non-membrane-bounded organelle 4 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A0A3S7X1A7
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

No structure information available for this entry

Related structures:

Function

Biological processes
Term Name Level Count
GO:0000723 telomere maintenance 5 10
GO:0006139 nucleobase-containing compound metabolic process 3 10
GO:0006259 DNA metabolic process 4 10
GO:0006281 DNA repair 5 10
GO:0006725 cellular aromatic compound metabolic process 3 10
GO:0006807 nitrogen compound metabolic process 2 10
GO:0006950 response to stress 2 10
GO:0006974 DNA damage response 4 10
GO:0006996 organelle organization 4 10
GO:0008152 metabolic process 1 10
GO:0009987 cellular process 1 10
GO:0016043 cellular component organization 3 10
GO:0032200 telomere organization 6 10
GO:0033554 cellular response to stress 3 10
GO:0034641 cellular nitrogen compound metabolic process 3 10
GO:0043170 macromolecule metabolic process 3 10
GO:0044237 cellular metabolic process 2 10
GO:0044238 primary metabolic process 2 10
GO:0044260 obsolete cellular macromolecule metabolic process 3 10
GO:0046483 heterocycle metabolic process 3 10
GO:0050896 response to stimulus 1 10
GO:0051276 chromosome organization 5 10
GO:0051716 cellular response to stimulus 2 10
GO:0071704 organic substance metabolic process 2 10
GO:0071840 cellular component organization or biogenesis 2 10
GO:0090304 nucleic acid metabolic process 4 10
GO:1901360 organic cyclic compound metabolic process 3 10
GO:0000722 telomere maintenance via recombination 6 1
GO:0006278 RNA-templated DNA biosynthetic process 6 1
GO:0006302 double-strand break repair 6 1
GO:0006310 DNA recombination 5 1
GO:0006312 mitotic recombination 6 1
GO:0007004 telomere maintenance via telomerase 7 1
GO:0009058 biosynthetic process 2 1
GO:0009059 macromolecule biosynthetic process 4 1
GO:0010833 telomere maintenance via telomere lengthening 6 1
GO:0018130 heterocycle biosynthetic process 4 1
GO:0019438 aromatic compound biosynthetic process 4 1
GO:0022402 cell cycle process 2 1
GO:0022414 reproductive process 1 1
GO:0032392 DNA geometric change 7 1
GO:0032508 DNA duplex unwinding 8 1
GO:0034654 nucleobase-containing compound biosynthetic process 4 1
GO:0044249 cellular biosynthetic process 3 1
GO:0044271 cellular nitrogen compound biosynthetic process 4 1
GO:0070192 chromosome organization involved in meiotic cell cycle 3 1
GO:0071103 DNA conformation change 6 1
GO:0071897 DNA biosynthetic process 5 1
GO:0090305 nucleic acid phosphodiester bond hydrolysis 5 1
GO:1901362 organic cyclic compound biosynthetic process 4 1
GO:1901576 organic substance biosynthetic process 3 1
GO:1903046 meiotic cell cycle process 2 1
Molecular functions
Term Name Level Count
GO:0000166 nucleotide binding 3 12
GO:0003824 catalytic activity 1 12
GO:0005488 binding 1 12
GO:0005524 ATP binding 5 12
GO:0008094 ATP-dependent activity, acting on DNA 2 10
GO:0016462 pyrophosphatase activity 5 10
GO:0016787 hydrolase activity 2 12
GO:0016817 hydrolase activity, acting on acid anhydrides 3 10
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 10
GO:0016887 ATP hydrolysis activity 7 10
GO:0017076 purine nucleotide binding 4 12
GO:0017111 ribonucleoside triphosphate phosphatase activity 6 10
GO:0030554 adenyl nucleotide binding 5 12
GO:0032553 ribonucleotide binding 3 12
GO:0032555 purine ribonucleotide binding 4 12
GO:0032559 adenyl ribonucleotide binding 5 12
GO:0035639 purine ribonucleoside triphosphate binding 4 12
GO:0036094 small molecule binding 2 12
GO:0043167 ion binding 2 12
GO:0043168 anion binding 3 12
GO:0043169 cation binding 3 12
GO:0046872 metal ion binding 4 12
GO:0097159 organic cyclic compound binding 2 12
GO:0097367 carbohydrate derivative binding 2 12
GO:0140097 catalytic activity, acting on DNA 3 10
GO:0140299 small molecule sensor activity 1 10
GO:0140612 DNA damage sensor activity 2 10
GO:0140640 catalytic activity, acting on a nucleic acid 2 10
GO:0140657 ATP-dependent activity 1 10
GO:0140664 ATP-dependent DNA damage sensor activity 3 10
GO:1901265 nucleoside phosphate binding 3 12
GO:1901363 heterocyclic compound binding 2 12
GO:0003676 nucleic acid binding 3 1
GO:0003677 DNA binding 4 1
GO:0003690 double-stranded DNA binding 5 1
GO:0003691 double-stranded telomeric DNA binding 6 1
GO:0003697 single-stranded DNA binding 5 1
GO:0042162 telomeric DNA binding 6 1
GO:0043047 single-stranded telomeric DNA binding 7 1
GO:0043565 sequence-specific DNA binding 5 1
GO:0051880 G-quadruplex DNA binding 5 1
GO:0098847 sequence-specific single stranded DNA binding 6 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 114 118 PF00656 0.474
CLV_C14_Caspase3-7 1295 1299 PF00656 0.503
CLV_NRD_NRD_1 1040 1042 PF00675 0.559
CLV_NRD_NRD_1 1049 1051 PF00675 0.547
CLV_NRD_NRD_1 1230 1232 PF00675 0.218
CLV_NRD_NRD_1 1307 1309 PF00675 0.362
CLV_NRD_NRD_1 204 206 PF00675 0.225
CLV_NRD_NRD_1 286 288 PF00675 0.574
CLV_NRD_NRD_1 291 293 PF00675 0.593
CLV_NRD_NRD_1 337 339 PF00675 0.468
CLV_NRD_NRD_1 453 455 PF00675 0.500
CLV_NRD_NRD_1 494 496 PF00675 0.612
CLV_NRD_NRD_1 635 637 PF00675 0.430
CLV_NRD_NRD_1 714 716 PF00675 0.443
CLV_NRD_NRD_1 824 826 PF00675 0.440
CLV_NRD_NRD_1 843 845 PF00675 0.407
CLV_NRD_NRD_1 905 907 PF00675 0.484
CLV_PCSK_KEX2_1 1049 1051 PF00082 0.571
CLV_PCSK_KEX2_1 1154 1156 PF00082 0.373
CLV_PCSK_KEX2_1 1230 1232 PF00082 0.207
CLV_PCSK_KEX2_1 1240 1242 PF00082 0.207
CLV_PCSK_KEX2_1 1307 1309 PF00082 0.362
CLV_PCSK_KEX2_1 177 179 PF00082 0.323
CLV_PCSK_KEX2_1 204 206 PF00082 0.215
CLV_PCSK_KEX2_1 286 288 PF00082 0.497
CLV_PCSK_KEX2_1 291 293 PF00082 0.507
CLV_PCSK_KEX2_1 328 330 PF00082 0.554
CLV_PCSK_KEX2_1 336 338 PF00082 0.459
CLV_PCSK_KEX2_1 452 454 PF00082 0.486
CLV_PCSK_KEX2_1 635 637 PF00082 0.467
CLV_PCSK_KEX2_1 672 674 PF00082 0.513
CLV_PCSK_KEX2_1 945 947 PF00082 0.649
CLV_PCSK_PC1ET2_1 1154 1156 PF00082 0.373
CLV_PCSK_PC1ET2_1 1240 1242 PF00082 0.212
CLV_PCSK_PC1ET2_1 177 179 PF00082 0.310
CLV_PCSK_PC1ET2_1 328 330 PF00082 0.570
CLV_PCSK_PC1ET2_1 672 674 PF00082 0.394
CLV_PCSK_PC1ET2_1 945 947 PF00082 0.623
CLV_PCSK_PC7_1 1236 1242 PF00082 0.207
CLV_PCSK_PC7_1 282 288 PF00082 0.509
CLV_PCSK_SKI1_1 1265 1269 PF00082 0.207
CLV_PCSK_SKI1_1 1308 1312 PF00082 0.304
CLV_PCSK_SKI1_1 174 178 PF00082 0.239
CLV_PCSK_SKI1_1 188 192 PF00082 0.232
CLV_PCSK_SKI1_1 205 209 PF00082 0.293
CLV_PCSK_SKI1_1 29 33 PF00082 0.230
CLV_PCSK_SKI1_1 453 457 PF00082 0.477
CLV_PCSK_SKI1_1 558 562 PF00082 0.385
CLV_PCSK_SKI1_1 596 600 PF00082 0.521
CLV_PCSK_SKI1_1 673 677 PF00082 0.439
CLV_PCSK_SKI1_1 85 89 PF00082 0.218
CLV_PCSK_SKI1_1 882 886 PF00082 0.594
CLV_PCSK_SKI1_1 977 981 PF00082 0.517
DEG_APCC_DBOX_1 258 266 PF00400 0.517
DEG_APCC_DBOX_1 470 478 PF00400 0.488
DEG_APCC_DBOX_1 557 565 PF00400 0.393
DEG_APCC_DBOX_1 672 680 PF00400 0.483
DEG_APCC_KENBOX_2 455 459 PF00400 0.392
DEG_COP1_1 137 147 PF00400 0.436
DEG_SPOP_SBC_1 130 134 PF00917 0.450
DOC_ANK_TNKS_1 494 501 PF00023 0.395
DOC_CYCLIN_RxL_1 604 614 PF00134 0.366
DOC_CYCLIN_RxL_1 958 968 PF00134 0.602
DOC_CYCLIN_RxL_1 985 993 PF00134 0.490
DOC_MAPK_gen_1 1154 1163 PF00069 0.367
DOC_MAPK_gen_1 1307 1318 PF00069 0.316
DOC_MAPK_gen_1 346 353 PF00069 0.511
DOC_MAPK_gen_1 471 479 PF00069 0.396
DOC_MAPK_gen_1 755 763 PF00069 0.478
DOC_MAPK_gen_1 985 994 PF00069 0.462
DOC_MAPK_MEF2A_6 1007 1016 PF00069 0.458
DOC_MAPK_MEF2A_6 1257 1266 PF00069 0.407
DOC_MAPK_MEF2A_6 473 481 PF00069 0.484
DOC_MAPK_MEF2A_6 746 754 PF00069 0.492
DOC_MAPK_MEF2A_6 81 88 PF00069 0.407
DOC_MAPK_MEF2A_6 985 994 PF00069 0.464
DOC_MAPK_NFAT4_5 81 89 PF00069 0.418
DOC_PP1_RVXF_1 108 114 PF00149 0.510
DOC_PP1_RVXF_1 83 89 PF00149 0.407
DOC_PP2B_LxvP_1 170 173 PF13499 0.414
DOC_PP2B_LxvP_1 992 995 PF13499 0.516
DOC_PP4_FxxP_1 27 30 PF00568 0.407
DOC_USP7_MATH_1 104 108 PF00917 0.458
DOC_USP7_MATH_1 1183 1187 PF00917 0.344
DOC_USP7_MATH_1 1229 1233 PF00917 0.440
DOC_USP7_MATH_1 296 300 PF00917 0.447
DOC_USP7_MATH_1 412 416 PF00917 0.465
DOC_USP7_MATH_1 576 580 PF00917 0.482
DOC_USP7_MATH_1 678 682 PF00917 0.504
DOC_USP7_MATH_1 702 706 PF00917 0.421
DOC_USP7_MATH_1 708 712 PF00917 0.436
DOC_USP7_MATH_1 740 744 PF00917 0.380
DOC_USP7_MATH_1 859 863 PF00917 0.641
DOC_USP7_MATH_1 951 955 PF00917 0.528
DOC_USP7_UBL2_3 1038 1042 PF12436 0.501
DOC_WW_Pin1_4 148 153 PF00397 0.432
DOC_WW_Pin1_4 720 725 PF00397 0.454
LIG_14-3-3_CanoR_1 1041 1045 PF00244 0.613
LIG_14-3-3_CanoR_1 1079 1085 PF00244 0.531
LIG_14-3-3_CanoR_1 110 120 PF00244 0.423
LIG_14-3-3_CanoR_1 1101 1106 PF00244 0.530
LIG_14-3-3_CanoR_1 1155 1161 PF00244 0.355
LIG_14-3-3_CanoR_1 1204 1208 PF00244 0.326
LIG_14-3-3_CanoR_1 1230 1234 PF00244 0.417
LIG_14-3-3_CanoR_1 1249 1259 PF00244 0.347
LIG_14-3-3_CanoR_1 136 144 PF00244 0.474
LIG_14-3-3_CanoR_1 309 319 PF00244 0.615
LIG_14-3-3_CanoR_1 635 639 PF00244 0.451
LIG_14-3-3_CanoR_1 882 890 PF00244 0.613
LIG_Actin_WH2_2 248 265 PF00022 0.510
LIG_Actin_WH2_2 805 822 PF00022 0.527
LIG_AP2alpha_1 180 184 PF02296 0.450
LIG_APCC_ABBA_1 652 657 PF00400 0.267
LIG_BIR_III_4 769 773 PF00653 0.368
LIG_BRCT_BRCA1_1 1268 1272 PF00533 0.407
LIG_BRCT_BRCA1_1 199 203 PF00533 0.456
LIG_Clathr_ClatBox_1 508 512 PF01394 0.483
LIG_DLG_GKlike_1 1101 1108 PF00625 0.378
LIG_FHA_1 1111 1117 PF00498 0.476
LIG_FHA_1 1163 1169 PF00498 0.342
LIG_FHA_1 1212 1218 PF00498 0.430
LIG_FHA_1 125 131 PF00498 0.418
LIG_FHA_1 1283 1289 PF00498 0.407
LIG_FHA_1 185 191 PF00498 0.407
LIG_FHA_1 30 36 PF00498 0.407
LIG_FHA_1 41 47 PF00498 0.407
LIG_FHA_1 626 632 PF00498 0.433
LIG_FHA_1 693 699 PF00498 0.467
LIG_FHA_1 814 820 PF00498 0.525
LIG_FHA_1 872 878 PF00498 0.529
LIG_FHA_2 1041 1047 PF00498 0.666
LIG_FHA_2 1105 1111 PF00498 0.445
LIG_FHA_2 1115 1121 PF00498 0.488
LIG_FHA_2 112 118 PF00498 0.474
LIG_FHA_2 1284 1290 PF00498 0.407
LIG_FHA_2 1317 1323 PF00498 0.278
LIG_FHA_2 262 268 PF00498 0.502
LIG_FHA_2 299 305 PF00498 0.539
LIG_FHA_2 42 48 PF00498 0.407
LIG_FHA_2 59 65 PF00498 0.407
LIG_FHA_2 734 740 PF00498 0.500
LIG_FHA_2 809 815 PF00498 0.460
LIG_FHA_2 937 943 PF00498 0.651
LIG_Integrin_isoDGR_2 280 282 PF01839 0.428
LIG_Integrin_RGD_1 1145 1147 PF01839 0.453
LIG_LIR_Gen_1 112 121 PF02991 0.429
LIG_LIR_Gen_1 1147 1156 PF02991 0.398
LIG_LIR_Gen_1 1158 1168 PF02991 0.300
LIG_LIR_Gen_1 1174 1184 PF02991 0.325
LIG_LIR_Gen_1 1344 1355 PF02991 0.292
LIG_LIR_Gen_1 653 662 PF02991 0.364
LIG_LIR_Gen_1 681 690 PF02991 0.368
LIG_LIR_Gen_1 739 747 PF02991 0.420
LIG_LIR_Gen_1 800 809 PF02991 0.432
LIG_LIR_Gen_1 862 871 PF02991 0.428
LIG_LIR_Nem_3 112 116 PF02991 0.453
LIG_LIR_Nem_3 1147 1152 PF02991 0.379
LIG_LIR_Nem_3 1158 1163 PF02991 0.350
LIG_LIR_Nem_3 1174 1180 PF02991 0.281
LIG_LIR_Nem_3 119 125 PF02991 0.422
LIG_LIR_Nem_3 1232 1238 PF02991 0.448
LIG_LIR_Nem_3 1334 1339 PF02991 0.324
LIG_LIR_Nem_3 1344 1350 PF02991 0.338
LIG_LIR_Nem_3 1352 1358 PF02991 0.310
LIG_LIR_Nem_3 653 658 PF02991 0.337
LIG_LIR_Nem_3 681 686 PF02991 0.374
LIG_LIR_Nem_3 739 744 PF02991 0.437
LIG_LIR_Nem_3 800 806 PF02991 0.431
LIG_LIR_Nem_3 862 866 PF02991 0.443
LIG_LYPXL_SIV_4 869 877 PF13949 0.513
LIG_NRBOX 301 307 PF00104 0.567
LIG_NRBOX 390 396 PF00104 0.529
LIG_PCNA_yPIPBox_3 1191 1203 PF02747 0.310
LIG_PDZ_Class_2 1355 1360 PF00595 0.272
LIG_Pex14_1 1203 1207 PF04695 0.309
LIG_Pex14_2 1355 1359 PF04695 0.253
LIG_Pex14_2 180 184 PF04695 0.407
LIG_RPA_C_Fungi 544 556 PF08784 0.338
LIG_RPA_C_Fungi 658 670 PF08784 0.336
LIG_RPA_C_Plants 966 977 PF08784 0.445
LIG_SH2_CRK 1235 1239 PF00017 0.286
LIG_SH2_GRB2like 1149 1152 PF00017 0.445
LIG_SH2_NCK_1 330 334 PF00017 0.447
LIG_SH2_NCK_1 870 874 PF00017 0.389
LIG_SH2_SRC 1149 1152 PF00017 0.445
LIG_SH2_SRC 655 658 PF00017 0.339
LIG_SH2_STAP1 330 334 PF00017 0.593
LIG_SH2_STAP1 655 659 PF00017 0.425
LIG_SH2_STAT5 1000 1003 PF00017 0.397
LIG_SH2_STAT5 1338 1341 PF00017 0.280
LIG_SH2_STAT5 189 192 PF00017 0.243
LIG_SH2_STAT5 379 382 PF00017 0.599
LIG_SH3_2 169 174 PF14604 0.258
LIG_SH3_3 166 172 PF00018 0.258
LIG_SH3_3 566 572 PF00018 0.488
LIG_SH3_3 66 72 PF00018 0.243
LIG_SUMO_SIM_anti_2 537 542 PF11976 0.430
LIG_SUMO_SIM_par_1 1213 1222 PF11976 0.447
LIG_SUMO_SIM_par_1 1277 1283 PF11976 0.243
LIG_SUMO_SIM_par_1 1314 1319 PF11976 0.280
LIG_SUMO_SIM_par_1 189 194 PF11976 0.258
LIG_SUMO_SIM_par_1 609 614 PF11976 0.428
LIG_SUMO_SIM_par_1 814 822 PF11976 0.464
LIG_TRAF2_1 1026 1029 PF00917 0.505
LIG_TRAF2_1 258 261 PF00917 0.290
LIG_TRAF2_1 264 267 PF00917 0.280
LIG_TRAF2_1 339 342 PF00917 0.542
LIG_TRAF2_1 490 493 PF00917 0.530
LIG_TRAF2_1 618 621 PF00917 0.464
LIG_TRAF2_1 690 693 PF00917 0.257
LIG_TRAF2_1 736 739 PF00917 0.449
LIG_TRAF2_1 862 865 PF00917 0.482
LIG_WRC_WIRS_1 12 17 PF05994 0.243
LIG_WRC_WIRS_1 709 714 PF05994 0.484
LIG_WRC_WIRS_1 99 104 PF05994 0.258
MOD_CK1_1 1083 1089 PF00069 0.531
MOD_CK1_1 1104 1110 PF00069 0.444
MOD_CK1_1 581 587 PF00069 0.412
MOD_CK1_1 625 631 PF00069 0.499
MOD_CK1_1 711 717 PF00069 0.553
MOD_CK2_1 1104 1110 PF00069 0.396
MOD_CK2_1 1114 1120 PF00069 0.374
MOD_CK2_1 1175 1181 PF00069 0.487
MOD_CK2_1 1216 1222 PF00069 0.537
MOD_CK2_1 1316 1322 PF00069 0.286
MOD_CK2_1 261 267 PF00069 0.281
MOD_CK2_1 41 47 PF00069 0.243
MOD_CK2_1 58 64 PF00069 0.276
MOD_CK2_1 624 630 PF00069 0.456
MOD_CK2_1 733 739 PF00069 0.437
MOD_CK2_1 808 814 PF00069 0.512
MOD_CK2_1 859 865 PF00069 0.513
MOD_CK2_1 915 921 PF00069 0.339
MOD_CK2_1 936 942 PF00069 0.672
MOD_GlcNHglycan 1020 1023 PF01048 0.544
MOD_GlcNHglycan 1050 1053 PF01048 0.580
MOD_GlcNHglycan 106 109 PF01048 0.387
MOD_GlcNHglycan 1177 1180 PF01048 0.391
MOD_GlcNHglycan 1252 1255 PF01048 0.243
MOD_GlcNHglycan 847 850 PF01048 0.692
MOD_GSK3_1 1110 1117 PF00069 0.472
MOD_GSK3_1 112 119 PF00069 0.184
MOD_GSK3_1 1162 1169 PF00069 0.468
MOD_GSK3_1 1203 1210 PF00069 0.325
MOD_GSK3_1 1218 1225 PF00069 0.531
MOD_GSK3_1 130 137 PF00069 0.303
MOD_GSK3_1 576 583 PF00069 0.444
MOD_GSK3_1 60 67 PF00069 0.274
MOD_GSK3_1 746 753 PF00069 0.448
MOD_GSK3_1 98 105 PF00069 0.250
MOD_N-GLC_1 514 519 PF02516 0.528
MOD_N-GLC_2 1003 1005 PF02516 0.430
MOD_N-GLC_2 51 53 PF02516 0.258
MOD_NEK2_1 102 107 PF00069 0.255
MOD_NEK2_1 116 121 PF00069 0.163
MOD_NEK2_1 184 189 PF00069 0.286
MOD_NEK2_1 308 313 PF00069 0.544
MOD_NEK2_1 580 585 PF00069 0.508
MOD_NEK2_1 808 813 PF00069 0.445
MOD_NEK2_1 819 824 PF00069 0.520
MOD_NEK2_1 86 91 PF00069 0.243
MOD_NEK2_1 990 995 PF00069 0.503
MOD_NEK2_2 678 683 PF00069 0.342
MOD_PIKK_1 296 302 PF00454 0.565
MOD_PIKK_1 501 507 PF00454 0.598
MOD_PIKK_1 587 593 PF00454 0.429
MOD_PIKK_1 839 845 PF00454 0.621
MOD_PK_1 746 752 PF00069 0.502
MOD_PKA_2 1016 1022 PF00069 0.561
MOD_PKA_2 1040 1046 PF00069 0.615
MOD_PKA_2 1048 1054 PF00069 0.529
MOD_PKA_2 109 115 PF00069 0.400
MOD_PKA_2 1156 1162 PF00069 0.353
MOD_PKA_2 1203 1209 PF00069 0.316
MOD_PKA_2 1229 1235 PF00069 0.258
MOD_PKA_2 1250 1256 PF00069 0.278
MOD_PKA_2 135 141 PF00069 0.337
MOD_PKA_2 308 314 PF00069 0.615
MOD_PKA_2 634 640 PF00069 0.579
MOD_PKA_2 819 825 PF00069 0.581
MOD_PKA_2 905 911 PF00069 0.372
MOD_PKB_1 195 203 PF00069 0.278
MOD_PKB_1 408 416 PF00069 0.471
MOD_Plk_1 1063 1069 PF00069 0.497
MOD_Plk_1 1077 1083 PF00069 0.415
MOD_Plk_1 116 122 PF00069 0.273
MOD_Plk_1 1166 1172 PF00069 0.457
MOD_Plk_1 1351 1357 PF00069 0.263
MOD_Plk_1 210 216 PF00069 0.317
MOD_Plk_1 387 393 PF00069 0.519
MOD_Plk_1 514 520 PF00069 0.502
MOD_Plk_1 813 819 PF00069 0.566
MOD_Plk_2-3 1211 1217 PF00069 0.403
MOD_Plk_2-3 1351 1357 PF00069 0.263
MOD_Plk_2-3 261 267 PF00069 0.357
MOD_Plk_4 1156 1162 PF00069 0.353
MOD_Plk_4 1258 1264 PF00069 0.248
MOD_Plk_4 210 216 PF00069 0.369
MOD_Plk_4 233 239 PF00069 0.359
MOD_Plk_4 29 35 PF00069 0.265
MOD_Plk_4 41 47 PF00069 0.323
MOD_Plk_4 64 70 PF00069 0.243
MOD_Plk_4 708 714 PF00069 0.535
MOD_Plk_4 746 752 PF00069 0.390
MOD_Plk_4 798 804 PF00069 0.387
MOD_Plk_4 996 1002 PF00069 0.470
MOD_ProDKin_1 148 154 PF00069 0.278
MOD_ProDKin_1 720 726 PF00069 0.457
MOD_SUMO_for_1 598 601 PF00179 0.406
MOD_SUMO_for_1 690 693 PF00179 0.311
MOD_SUMO_rev_2 67 75 PF00179 0.246
MOD_SUMO_rev_2 77 82 PF00179 0.249
MOD_SUMO_rev_2 900 909 PF00179 0.590
TRG_DiLeu_BaEn_2 63 69 PF01217 0.258
TRG_DiLeu_BaEn_4 601 607 PF01217 0.337
TRG_DiLeu_BaLyEn_6 390 395 PF01217 0.528
TRG_DiLeu_BaLyEn_6 82 87 PF01217 0.258
TRG_ENDOCYTIC_2 1149 1152 PF00928 0.378
TRG_ENDOCYTIC_2 1177 1180 PF00928 0.320
TRG_ENDOCYTIC_2 1235 1238 PF00928 0.286
TRG_ENDOCYTIC_2 655 658 PF00928 0.520
TRG_ENDOCYTIC_2 683 686 PF00928 0.350
TRG_ENDOCYTIC_2 741 744 PF00928 0.426
TRG_ENDOCYTIC_2 803 806 PF00928 0.383
TRG_ENDOCYTIC_2 863 866 PF00928 0.435
TRG_ER_diArg_1 1248 1251 PF00400 0.258
TRG_ER_diArg_1 203 205 PF00400 0.267
TRG_ER_diArg_1 290 292 PF00400 0.602
TRG_ER_diArg_1 336 338 PF00400 0.531
TRG_ER_diArg_1 451 454 PF00400 0.512
TRG_ER_diArg_1 758 761 PF00400 0.458
TRG_ER_diArg_1 938 941 PF00400 0.623
TRG_NES_CRM1_1 559 573 PF08389 0.471
TRG_Pf-PMV_PEXEL_1 1007 1011 PF00026 0.590
TRG_Pf-PMV_PEXEL_1 1294 1298 PF00026 0.243
TRG_Pf-PMV_PEXEL_1 1301 1305 PF00026 0.301
TRG_Pf-PMV_PEXEL_1 1326 1331 PF00026 0.311
TRG_Pf-PMV_PEXEL_1 205 209 PF00026 0.337
TRG_Pf-PMV_PEXEL_1 253 257 PF00026 0.438
TRG_Pf-PMV_PEXEL_1 369 373 PF00026 0.511
TRG_Pf-PMV_PEXEL_1 453 457 PF00026 0.544
TRG_Pf-PMV_PEXEL_1 506 510 PF00026 0.593
TRG_Pf-PMV_PEXEL_1 596 601 PF00026 0.383
TRG_Pf-PMV_PEXEL_1 609 614 PF00026 0.265
TRG_Pf-PMV_PEXEL_1 901 905 PF00026 0.623
TRG_Pf-PMV_PEXEL_1 928 932 PF00026 0.542
TRG_Pf-PMV_PEXEL_1 985 989 PF00026 0.534

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1I3D5 Leptomonas seymouri 70% 100%
A0A0S4JAY7 Bodo saltans 38% 100%
A0A1X0NYH4 Trypanosomatidae 47% 100%
A0A3R7N260 Trypanosoma rangeli 47% 100%
A4HG93 Leishmania braziliensis 84% 100%
A4I3C7 Leishmania infantum 100% 100%
D0A818 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 45% 100%
E9AZL4 Leishmania mexicana (strain MHOM/GT/2001/U1103) 93% 100%
P70388 Mus musculus 28% 100%
Q4Q8L7 Leishmania major 94% 100%
Q92878 Homo sapiens 28% 100%
V5BQC9 Trypanosoma cruzi 46% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS