LeishMANIAdb
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Leishmanolysin

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Leishmanolysin
Gene product:
major surface protease gp63, putative
Species:
Leishmania donovani
UniProt:
A0A3S7X192_LEIDO
TriTrypDb:
LdBPK_280600.1 , LdCL_280010700 , LDHU3_28.0770
Length:
566

Annotations

LeishMANIAdb annotations

Publication identifier(s): 31356625
GPI-anchored cell surface protease. Broad-spectrum ectoenzyme involved in pathogenesis. Heavily expanded family in all parazitic species.. Localization: Cell surface (experimental)

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 2
Forrest at al. (procyclic) no yes: 4
Silverman et al. no yes: 0
Pissara et al. yes yes: 72
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 5
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 76, no: 32
NetGPI no yes: 0, no: 108
Cellular components
Term Name Level Count
GO:0016020 membrane 2 109
GO:0110165 cellular anatomical entity 1 109
GO:0005737 cytoplasm 2 6
GO:0018995 host cellular component 2 4
GO:0033643 host cell part 3 4
GO:0033646 host intracellular part 4 4
GO:0033647 host intracellular organelle 5 4
GO:0033648 host intracellular membrane-bounded organelle 6 4
GO:0042025 host cell nucleus 7 4

Expansion

Sequence features

A0A3S7X192
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X192

Function

Biological processes
Term Name Level Count
GO:0006508 proteolysis 4 109
GO:0006807 nitrogen compound metabolic process 2 109
GO:0007155 cell adhesion 2 109
GO:0008152 metabolic process 1 109
GO:0009987 cellular process 1 109
GO:0019538 protein metabolic process 3 109
GO:0043170 macromolecule metabolic process 3 109
GO:0044238 primary metabolic process 2 109
GO:0071704 organic substance metabolic process 2 109
GO:1901564 organonitrogen compound metabolic process 3 109
GO:0009966 regulation of signal transduction 4 4
GO:0010646 regulation of cell communication 4 4
GO:0010749 regulation of nitric oxide mediated signal transduction 6 4
GO:0023051 regulation of signaling 3 4
GO:0035821 modulation of process of another organism 2 4
GO:0044003 modulation by symbiont of host process 3 4
GO:0044068 modulation by symbiont of host cellular process 4 4
GO:0044081 modulation by symbiont of host nitric oxide-mediated signal transduction 5 4
GO:0044403 biological process involved in symbiotic interaction 2 4
GO:0044419 biological process involved in interspecies interaction between organisms 1 4
GO:0044501 modulation of signal transduction in another organism 3 4
GO:0048583 regulation of response to stimulus 3 4
GO:0050789 regulation of biological process 2 4
GO:0050794 regulation of cellular process 3 4
GO:0051701 biological process involved in interaction with host 3 4
GO:0052027 modulation by symbiont of host signal transduction pathway 4 4
GO:0065007 biological regulation 1 4
GO:0075130 modulation by symbiont of host protein kinase-mediated signal transduction 5 4
GO:1902531 regulation of intracellular signal transduction 5 4
Molecular functions
Term Name Level Count
GO:0003824 catalytic activity 1 109
GO:0004175 endopeptidase activity 4 109
GO:0004222 metalloendopeptidase activity 5 109
GO:0005488 binding 1 109
GO:0008233 peptidase activity 3 109
GO:0008237 metallopeptidase activity 4 109
GO:0016787 hydrolase activity 2 109
GO:0043167 ion binding 2 109
GO:0043169 cation binding 3 109
GO:0046872 metal ion binding 4 109
GO:0140096 catalytic activity, acting on a protein 2 109
GO:0008047 enzyme activator activity 3 4
GO:0008160 protein tyrosine phosphatase activator activity 6 4
GO:0019208 phosphatase regulator activity 3 4
GO:0019211 phosphatase activator activity 4 4
GO:0019888 protein phosphatase regulator activity 4 4
GO:0030234 enzyme regulator activity 2 4
GO:0072542 protein phosphatase activator activity 5 4
GO:0098772 molecular function regulator activity 1 4
GO:0140677 molecular function activator activity 2 4

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 29 33 PF00656 0.542
CLV_C14_Caspase3-7 374 378 PF00656 0.371
CLV_MEL_PAP_1 48 54 PF00089 0.455
CLV_NRD_NRD_1 2 4 PF00675 0.736
CLV_NRD_NRD_1 304 306 PF00675 0.498
CLV_NRD_NRD_1 386 388 PF00675 0.546
CLV_PCSK_KEX2_1 122 124 PF00082 0.633
CLV_PCSK_KEX2_1 2 4 PF00082 0.735
CLV_PCSK_KEX2_1 303 305 PF00082 0.496
CLV_PCSK_KEX2_1 386 388 PF00082 0.546
CLV_PCSK_PC1ET2_1 122 124 PF00082 0.632
CLV_PCSK_PC1ET2_1 303 305 PF00082 0.533
CLV_PCSK_SKI1_1 122 126 PF00082 0.589
CLV_PCSK_SKI1_1 219 223 PF00082 0.474
CLV_PCSK_SKI1_1 243 247 PF00082 0.574
CLV_PCSK_SKI1_1 3 7 PF00082 0.624
CLV_PCSK_SKI1_1 305 309 PF00082 0.548
CLV_PCSK_SKI1_1 391 395 PF00082 0.558
CLV_PCSK_SKI1_1 538 542 PF00082 0.534
DEG_APCC_DBOX_1 1 9 PF00400 0.617
DEG_APCC_DBOX_1 122 130 PF00400 0.265
DEG_Nend_UBRbox_1 1 4 PF02207 0.564
DOC_ANK_TNKS_1 492 499 PF00023 0.242
DOC_CKS1_1 453 458 PF01111 0.253
DOC_CYCLIN_RxL_1 119 127 PF00134 0.405
DOC_MAPK_gen_1 119 128 PF00069 0.424
DOC_MAPK_gen_1 2 10 PF00069 0.593
DOC_MAPK_HePTP_8 116 128 PF00069 0.249
DOC_MAPK_MEF2A_6 119 128 PF00069 0.455
DOC_MAPK_MEF2A_6 2 10 PF00069 0.523
DOC_MAPK_NFAT4_5 123 131 PF00069 0.251
DOC_PP2B_LxvP_1 128 131 PF13499 0.251
DOC_PP4_FxxP_1 165 168 PF00568 0.362
DOC_PP4_FxxP_1 408 411 PF00568 0.327
DOC_USP7_MATH_1 548 552 PF00917 0.628
DOC_WW_Pin1_4 150 155 PF00397 0.313
DOC_WW_Pin1_4 214 219 PF00397 0.403
DOC_WW_Pin1_4 258 263 PF00397 0.316
DOC_WW_Pin1_4 452 457 PF00397 0.461
DOC_WW_Pin1_4 504 509 PF00397 0.379
LIG_14-3-3_CanoR_1 108 117 PF00244 0.366
LIG_14-3-3_CanoR_1 2 6 PF00244 0.695
LIG_14-3-3_CanoR_1 208 212 PF00244 0.256
LIG_14-3-3_CanoR_1 304 312 PF00244 0.320
LIG_14-3-3_CanoR_1 391 401 PF00244 0.366
LIG_14-3-3_CanoR_1 51 55 PF00244 0.685
LIG_14-3-3_CanoR_1 538 545 PF00244 0.652
LIG_14-3-3_CanoR_1 549 559 PF00244 0.746
LIG_APCC_ABBA_1 134 139 PF00400 0.347
LIG_APCC_ABBA_1 80 85 PF00400 0.296
LIG_APCC_ABBAyCdc20_2 79 85 PF00400 0.296
LIG_BRCT_BRCA1_1 506 510 PF00533 0.420
LIG_BRCT_BRCA1_2 506 512 PF00533 0.267
LIG_FHA_1 225 231 PF00498 0.465
LIG_FHA_1 240 246 PF00498 0.387
LIG_FHA_1 363 369 PF00498 0.363
LIG_FHA_1 436 442 PF00498 0.324
LIG_FHA_1 498 504 PF00498 0.345
LIG_FHA_1 551 557 PF00498 0.665
LIG_FHA_1 60 66 PF00498 0.558
LIG_FHA_1 82 88 PF00498 0.375
LIG_FHA_1 9 15 PF00498 0.536
LIG_GBD_Chelix_1 555 563 PF00786 0.780
LIG_Integrin_isoDGR_2 206 208 PF01839 0.556
LIG_LIR_Gen_1 11 19 PF02991 0.550
LIG_LIR_Gen_1 403 413 PF02991 0.405
LIG_LIR_Gen_1 519 528 PF02991 0.416
LIG_LIR_Gen_1 534 540 PF02991 0.504
LIG_LIR_Nem_3 11 15 PF02991 0.548
LIG_LIR_Nem_3 178 184 PF02991 0.397
LIG_LIR_Nem_3 403 408 PF02991 0.404
LIG_LIR_Nem_3 421 425 PF02991 0.306
LIG_LIR_Nem_3 519 523 PF02991 0.396
LIG_LIR_Nem_3 531 536 PF02991 0.456
LIG_LIR_Nem_3 72 78 PF02991 0.321
LIG_MAD2 123 131 PF02301 0.427
LIG_NRBOX 124 130 PF00104 0.251
LIG_SH2_CRK 321 325 PF00017 0.368
LIG_SH2_CRK 536 540 PF00017 0.344
LIG_SH2_NCK_1 339 343 PF00017 0.296
LIG_SH2_STAP1 536 540 PF00017 0.334
LIG_SH2_STAT5 220 223 PF00017 0.365
LIG_SH2_STAT5 404 407 PF00017 0.378
LIG_SH3_3 148 154 PF00018 0.275
LIG_SH3_3 373 379 PF00018 0.258
LIG_SH3_3 450 456 PF00018 0.465
LIG_SH3_3 55 61 PF00018 0.752
LIG_SUMO_SIM_anti_2 50 56 PF11976 0.570
LIG_WRC_WIRS_1 254 259 PF05994 0.467
MOD_CDK_SPK_2 214 219 PF00069 0.433
MOD_CDK_SPxxK_3 150 157 PF00069 0.399
MOD_CDK_SPxxK_3 260 267 PF00069 0.299
MOD_CK1_1 322 328 PF00069 0.367
MOD_CK1_1 381 387 PF00069 0.390
MOD_CK1_1 396 402 PF00069 0.376
MOD_CK1_1 504 510 PF00069 0.408
MOD_CK1_1 519 525 PF00069 0.388
MOD_CK1_1 53 59 PF00069 0.733
MOD_CK1_1 88 94 PF00069 0.474
MOD_CK1_1 97 103 PF00069 0.254
MOD_CK2_1 163 169 PF00069 0.370
MOD_CK2_1 528 534 PF00069 0.412
MOD_CK2_1 53 59 PF00069 0.446
MOD_GlcNHglycan 111 114 PF01048 0.601
MOD_GlcNHglycan 131 134 PF01048 0.577
MOD_GlcNHglycan 185 188 PF01048 0.485
MOD_GlcNHglycan 190 193 PF01048 0.500
MOD_GlcNHglycan 267 270 PF01048 0.586
MOD_GlcNHglycan 305 308 PF01048 0.572
MOD_GlcNHglycan 315 318 PF01048 0.553
MOD_GlcNHglycan 321 324 PF01048 0.570
MOD_GlcNHglycan 462 466 PF01048 0.548
MOD_GlcNHglycan 479 482 PF01048 0.566
MOD_GlcNHglycan 489 492 PF01048 0.632
MOD_GlcNHglycan 96 99 PF01048 0.608
MOD_GSK3_1 183 190 PF00069 0.359
MOD_GSK3_1 392 399 PF00069 0.397
MOD_GSK3_1 457 464 PF00069 0.378
MOD_GSK3_1 497 504 PF00069 0.370
MOD_GSK3_1 534 541 PF00069 0.493
MOD_GSK3_1 543 550 PF00069 0.561
MOD_GSK3_1 81 88 PF00069 0.385
MOD_LATS_1 301 307 PF00433 0.324
MOD_N-GLC_1 501 506 PF02516 0.651
MOD_N-GLC_1 528 533 PF02516 0.566
MOD_N-GLC_1 88 93 PF02516 0.529
MOD_NEK2_1 1 6 PF00069 0.583
MOD_NEK2_1 183 188 PF00069 0.328
MOD_NEK2_1 239 244 PF00069 0.402
MOD_NEK2_1 329 334 PF00069 0.283
MOD_NEK2_1 441 446 PF00069 0.302
MOD_NEK2_1 47 52 PF00069 0.530
MOD_PIKK_1 280 286 PF00454 0.420
MOD_PIKK_1 363 369 PF00454 0.422
MOD_PIKK_1 88 94 PF00454 0.251
MOD_PK_1 157 163 PF00069 0.242
MOD_PKA_1 157 163 PF00069 0.242
MOD_PKA_1 303 309 PF00069 0.324
MOD_PKA_2 1 7 PF00069 0.659
MOD_PKA_2 100 106 PF00069 0.448
MOD_PKA_2 107 113 PF00069 0.456
MOD_PKA_2 207 213 PF00069 0.341
MOD_PKA_2 303 309 PF00069 0.326
MOD_PKA_2 50 56 PF00069 0.582
MOD_PKA_2 548 554 PF00069 0.798
MOD_Plk_1 429 435 PF00069 0.369
MOD_Plk_1 461 467 PF00069 0.395
MOD_Plk_1 501 507 PF00069 0.428
MOD_Plk_1 528 534 PF00069 0.404
MOD_Plk_1 541 547 PF00069 0.503
MOD_Plk_4 190 196 PF00069 0.385
MOD_Plk_4 400 406 PF00069 0.415
MOD_Plk_4 441 447 PF00069 0.302
MOD_Plk_4 50 56 PF00069 0.609
MOD_Plk_4 528 534 PF00069 0.366
MOD_ProDKin_1 150 156 PF00069 0.313
MOD_ProDKin_1 214 220 PF00069 0.403
MOD_ProDKin_1 258 264 PF00069 0.316
MOD_ProDKin_1 452 458 PF00069 0.461
MOD_ProDKin_1 504 510 PF00069 0.379
MOD_SUMO_for_1 307 310 PF00179 0.348
MOD_SUMO_for_1 340 343 PF00179 0.249
MOD_SUMO_rev_2 115 124 PF00179 0.320
TRG_DiLeu_BaEn_1 535 540 PF01217 0.332
TRG_DiLeu_LyEn_5 535 540 PF01217 0.332
TRG_ENDOCYTIC_2 321 324 PF00928 0.345
TRG_ENDOCYTIC_2 446 449 PF00928 0.441
TRG_ENDOCYTIC_2 520 523 PF00928 0.366
TRG_ENDOCYTIC_2 536 539 PF00928 0.502
TRG_ER_diArg_1 1 3 PF00400 0.749
TRG_Pf-PMV_PEXEL_1 123 127 PF00026 0.532
TRG_Pf-PMV_PEXEL_1 538 542 PF00026 0.373

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IL11 Leptomonas seymouri 41% 86%
A0A0S4IS53 Bodo saltans 39% 100%
A0A0S4IUT6 Bodo saltans 30% 69%
A0A0S4IUU1 Bodo saltans 30% 86%
A0A0S4IYM3 Bodo saltans 31% 78%
A0A1B0GTW7 Homo sapiens 25% 72%
A0A1D5NSK0 Danio rerio 25% 91%
A0A1X0NDG7 Trypanosomatidae 31% 87%
A0A1X0NDJ3 Trypanosomatidae 28% 78%
A0A1X0NDK2 Trypanosomatidae 32% 98%
A0A1X0NDK7 Trypanosomatidae 30% 79%
A0A1X0NDK9 Trypanosomatidae 29% 100%
A0A1X0NDM7 Trypanosomatidae 29% 88%
A0A1X0NDU8 Trypanosomatidae 28% 85%
A0A1X0NE71 Trypanosomatidae 29% 100%
A0A1X0NER9 Trypanosomatidae 33% 88%
A0A1X0NET7 Trypanosomatidae 32% 100%
A0A1X0NEX7 Trypanosomatidae 34% 86%
A0A1X0NEZ6 Trypanosomatidae 31% 87%
A0A1X0NF32 Trypanosomatidae 28% 100%
A0A1X0NF41 Trypanosomatidae 30% 92%
A0A1X0NFJ0 Trypanosomatidae 31% 100%
A0A1X0NFK3 Trypanosomatidae 29% 84%
A0A1X0NFU4 Trypanosomatidae 29% 69%
A0A1X0NFZ9 Trypanosomatidae 31% 100%
A0A1X0NG20 Trypanosomatidae 30% 91%
A0A1X0NGN3 Trypanosomatidae 37% 100%
A0A1X0NGP3 Trypanosomatidae 30% 66%
A0A1X0NGY3 Trypanosomatidae 28% 74%
A0A1X0NGZ3 Trypanosomatidae 30% 94%
A0A1X0NHP6 Trypanosomatidae 30% 100%
A0A1X0NHQ6 Trypanosomatidae 31% 100%
A0A1X0NI74 Trypanosomatidae 28% 76%
A0A1X0NII4 Trypanosomatidae 27% 67%
A0A1X0NIZ3 Trypanosomatidae 31% 100%
A0A1X0NJS3 Trypanosomatidae 30% 87%
A0A1X0NK66 Trypanosomatidae 30% 86%
A0A1X0NKJ8 Trypanosomatidae 29% 76%
A0A1X0NKW9 Trypanosomatidae 32% 100%
A0A1X0NME2 Trypanosomatidae 32% 90%
A0A1X0NMK3 Trypanosomatidae 27% 100%
A0A1X0NMK7 Trypanosomatidae 37% 100%
A0A1X0NMV0 Trypanosomatidae 29% 77%
A0A1X0NN43 Trypanosomatidae 31% 79%
A0A1X0NNK8 Trypanosomatidae 31% 86%
A0A1X0NPW0 Trypanosomatidae 29% 88%
A0A1X0NQJ5 Trypanosomatidae 33% 100%
A0A1X0NQM4 Trypanosomatidae 32% 100%
A0A1X0NQN3 Trypanosomatidae 36% 100%
A0A1X0NQU4 Trypanosomatidae 35% 88%
A0A1X0NQW6 Trypanosomatidae 30% 99%
A0A1X0NRF3 Trypanosomatidae 29% 84%
A0A1X0NRY8 Trypanosomatidae 35% 100%
A0A1X0NTJ1 Trypanosomatidae 31% 100%
A0A1X0NU16 Trypanosomatidae 38% 94%
A0A1X0NUR2 Trypanosomatidae 31% 77%
A0A1X0NV28 Trypanosomatidae 40% 96%
A0A1X0NVC3 Trypanosomatidae 30% 83%
A0A1X0NVE0 Trypanosomatidae 30% 72%
A0A1X0NW07 Trypanosomatidae 29% 90%
A0A1X0NX94 Trypanosomatidae 30% 87%
A0A1X0NX98 Trypanosomatidae 29% 71%
A0A1X0NXB6 Trypanosomatidae 31% 80%
A0A1X0NXH6 Trypanosomatidae 31% 77%
A0A1X0NXQ4 Trypanosomatidae 32% 83%
A0A1X0NXR7 Trypanosomatidae 33% 75%
A0A1X0NY94 Trypanosomatidae 39% 100%
A0A1X0NYE3 Trypanosomatidae 31% 91%
A0A1X0NYE7 Trypanosomatidae 32% 100%
A0A1X0NYN2 Trypanosomatidae 35% 100%
A0A1X0NYN4 Trypanosomatidae 29% 79%
A0A1X0NYS5 Trypanosomatidae 37% 94%
A0A1X0NYZ2 Trypanosomatidae 37% 100%
A0A1X0NZ46 Trypanosomatidae 32% 97%
A0A1X0NZ63 Trypanosomatidae 30% 89%
A0A1X0NZN6 Trypanosomatidae 31% 87%
A0A1X0P055 Trypanosomatidae 35% 96%
A0A1X0P0C4 Trypanosomatidae 30% 100%
A0A1X0P154 Trypanosomatidae 32% 94%
A0A1X0P331 Trypanosomatidae 35% 99%
A0A1X0P3K0 Trypanosomatidae 27% 78%
A0A1X0P3S2 Trypanosomatidae 30% 100%
A0A1X0P4L8 Trypanosomatidae 28% 100%
A0A1X0P4Y5 Trypanosomatidae 28% 88%
A0A1X0P544 Trypanosomatidae 29% 88%
A0A1X0P5J0 Trypanosomatidae 31% 83%
A0A1X0P7R3 Trypanosomatidae 39% 100%
A0A1X0P8B4 Trypanosomatidae 30% 100%
A0A1X0P9Z4 Trypanosomatidae 34% 100%
A0A1X0PB04 Trypanosomatidae 31% 100%
A0A3Q8I8N3 Leishmania donovani 37% 100%
A0A3Q8I8P8 Leishmania donovani 36% 100%
A0A3Q8I8S6 Leishmania donovani 38% 100%
A0A3Q8I8S9 Leishmania donovani 36% 100%
A0A3Q8IAZ8 Leishmania donovani 37% 100%
A0A3Q8IC35 Leishmania donovani 37% 100%
A0A3Q8IC44 Leishmania donovani 36% 100%
A0A3Q8IH61 Leishmania donovani 36% 100%
A0A3Q8IIN4 Leishmania donovani 41% 100%
A0A3R7JT49 Trypanosoma rangeli 36% 67%
A0A3R7JTB6 Trypanosoma rangeli 34% 81%
A0A3R7JUS0 Trypanosoma rangeli 36% 100%
A0A3R7JV87 Trypanosoma rangeli 35% 100%
A0A3R7K7T9 Trypanosoma rangeli 36% 94%
A0A3R7K9S1 Trypanosoma rangeli 35% 100%
A0A3R7KLR6 Trypanosoma rangeli 32% 88%
A0A3R7KMY2 Trypanosoma rangeli 36% 85%
A0A3R7LFC4 Trypanosoma rangeli 37% 84%
A0A3R7LFZ4 Trypanosoma rangeli 41% 100%
A0A3R7LWG1 Trypanosoma rangeli 36% 100%
A0A3R7LX11 Trypanosoma rangeli 36% 100%
A0A3R7M1R8 Trypanosoma rangeli 34% 98%
A0A3R7M574 Trypanosoma rangeli 35% 88%
A0A3R7M5K4 Trypanosoma rangeli 38% 100%
A0A3R7M7N6 Trypanosoma rangeli 35% 82%
A0A3R7MTS2 Trypanosoma rangeli 42% 100%
A0A3R7MW36 Trypanosoma rangeli 35% 100%
A0A3R7MXF4 Trypanosoma rangeli 41% 92%
A0A3R7N1W7 Trypanosoma rangeli 35% 97%
A0A3R7N289 Trypanosoma rangeli 35% 78%
A0A3R7N7I3 Trypanosoma rangeli 44% 100%
A0A3R7NTI8 Trypanosoma rangeli 34% 99%
A0A3R7R2J4 Trypanosoma rangeli 36% 88%
A0A3R7R5R1 Trypanosoma rangeli 35% 94%
A0A3R7R818 Trypanosoma rangeli 36% 100%
A0A3S5H6G0 Leishmania donovani 36% 100%
A0A3S5IQY2 Trypanosoma rangeli 40% 100%
A0A3S7WR43 Leishmania donovani 37% 100%
A0A3S7WR46 Leishmania donovani 38% 100%
A0A3S7WR60 Leishmania donovani 37% 100%
A0A422MRQ6 Trypanosoma rangeli 35% 76%
A0A422MTA9 Trypanosoma rangeli 34% 78%
A0A422MU95 Trypanosoma rangeli 36% 99%
A0A422MVF5 Trypanosoma rangeli 37% 100%
A0A422MVS3 Trypanosoma rangeli 36% 100%
A0A422MW99 Trypanosoma rangeli 35% 76%
A0A422MZ47 Trypanosoma rangeli 38% 100%
A0A422MZG4 Trypanosoma rangeli 37% 96%
A0A422N361 Trypanosoma rangeli 36% 100%
A0A422N7Q6 Trypanosoma rangeli 36% 87%
A0A422NDS2 Trypanosoma rangeli 35% 97%
A0A422NDT3 Trypanosoma rangeli 32% 99%
A0A422NP82 Trypanosoma rangeli 40% 99%
A4H626 Leishmania braziliensis 37% 100%
A4H627 Leishmania braziliensis 38% 100%
A4H629 Leishmania braziliensis 39% 100%
A4H630 Leishmania braziliensis 39% 100%
A4H631 Leishmania braziliensis 39% 100%
A4H632 Leishmania braziliensis 38% 100%
A4H633 Leishmania braziliensis 38% 100%
A4H634 Leishmania braziliensis 39% 100%
A4H635 Leishmania braziliensis 39% 100%
A4H636 Leishmania braziliensis 38% 100%
A4H637 Leishmania braziliensis 38% 100%
A4H638 Leishmania braziliensis 38% 100%
A4H639 Leishmania braziliensis 37% 100%
A4H640 Leishmania braziliensis 39% 100%
A4H6D3 Leishmania braziliensis 35% 100%
A4H6D5 Leishmania braziliensis 37% 80%
A4H6D7 Leishmania braziliensis 37% 100%
A4H6D8 Leishmania braziliensis 37% 100%
A4H6D9 Leishmania braziliensis 37% 100%
A4H6E0 Leishmania braziliensis 37% 80%
A4H6E1 Leishmania braziliensis 36% 100%
A4H6E2 Leishmania braziliensis 34% 100%
A4H6E3 Leishmania braziliensis 38% 100%
A4H6E4 Leishmania braziliensis 38% 100%
A4H6E5 Leishmania braziliensis 40% 100%
A4HJI2 Leishmania braziliensis 40% 100%
A4HUF6 Leishmania infantum 37% 100%
A4HUF8 Leishmania infantum 38% 100%
A4HUF9 Leishmania infantum 36% 100%
A4HUG0 Leishmania infantum 36% 100%
A4I6X5 Leishmania infantum 41% 100%
C9ZUT5 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 39% 97%
D0A1R8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 33% 96%
D0A7S8 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 31% 84%
D0A855 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 39% 92%
E9AHH5 Leishmania infantum 99% 100%
E9AN53 Leishmania mexicana (strain MHOM/GT/2001/U1103) 38% 100%
E9AN54 Leishmania mexicana (strain MHOM/GT/2001/U1103) 35% 100%
E9AN55 Leishmania mexicana (strain MHOM/GT/2001/U1103) 36% 100%
E9AN56 Leishmania mexicana (strain MHOM/GT/2001/U1103) 39% 100%
E9AN57 Leishmania mexicana (strain MHOM/GT/2001/U1103) 36% 100%
E9AZL8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 82% 100%
E9B1Z9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 40% 100%
O62446 Caenorhabditis elegans 24% 85%
P08148 Leishmania major 39% 94%
P15706 Leishmania chagasi 36% 94%
P23223 Leishmania donovani 38% 96%
P43150 Leishmania mexicana 39% 88%
Q00689 Leishmania guyanensis 38% 91%
Q06031 Crithidia fasciculata 35% 87%
Q27673 Leishmania amazonensis 38% 95%
Q29AK2 Drosophila pseudoobscura pseudoobscura 25% 83%
Q4Q662 Leishmania major 42% 100%
Q4Q8L3 Leishmania major 84% 100%
Q4QHG9 Leishmania major 39% 100%
Q4QHH0 Leishmania major 38% 100%
Q4QHH1 Leishmania major 39% 100%
Q4QHH2 Leishmania major 39% 100%
Q61YG1 Caenorhabditis briggsae 24% 85%
Q6LA77 Leishmania infantum 36% 100%
Q8BMN4 Mus musculus 28% 83%
Q8MNZ1 Leishmania tropica 36% 86%
Q96KR4 Homo sapiens 24% 86%
Q9VH19 Drosophila melanogaster 23% 83%
V5A303 Trypanosoma cruzi 41% 100%
V5A359 Trypanosoma cruzi 40% 100%
V5A488 Trypanosoma cruzi 34% 70%
V5AII7 Trypanosoma cruzi 39% 100%
V5AMH8 Trypanosoma cruzi 35% 100%
V5AN34 Trypanosoma cruzi 42% 100%
V5APQ4 Trypanosoma cruzi 34% 71%
V5AX72 Trypanosoma cruzi 35% 77%
V5B5M0 Trypanosoma cruzi 35% 77%
V5B9W5 Trypanosoma cruzi 30% 84%
V5BAL3 Trypanosoma cruzi 39% 100%
V5BAN1 Trypanosoma cruzi 36% 72%
V5BD39 Trypanosoma cruzi 43% 100%
V5BLT3 Trypanosoma cruzi 32% 90%
V5CI97 Trypanosoma cruzi 33% 89%
V5CIA7 Trypanosoma cruzi 34% 100%
V5D358 Trypanosoma cruzi 35% 67%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS