LeishMANIAdb
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BTB/POZ_domain_containing_protein_putative/Pfam:P F02214

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
BTB/POZ_domain_containing_protein_putative/Pfam:P F02214
Gene product:
btb/poz domain containing protein, putative
Species:
Leishmania donovani
UniProt:
A0A3S7X191_LEIDO
TriTrypDb:
LdBPK_280740.1 , LdCL_280012000 , LDHU3_28.0910
Length:
475

Annotations

Annotations by Jardim et al.

Transporters, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 5
NetGPI no yes: 0, no: 5
Cellular components
Term Name Level Count
GO:0005634 nucleus 5 1
GO:0005737 cytoplasm 2 1
GO:0032838 plasma membrane bounded cell projection cytoplasm 4 1
GO:0043226 organelle 2 1
GO:0043227 membrane-bounded organelle 3 1
GO:0043229 intracellular organelle 3 1
GO:0043231 intracellular membrane-bounded organelle 4 1
GO:0097014 ciliary plasm 5 1
GO:0099568 cytoplasmic region 3 1
GO:0110165 cellular anatomical entity 1 1

Expansion

Sequence features

A0A3S7X191
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X191

Function

Biological processes
Term Name Level Count
GO:0009987 cellular process 1 6
GO:0016043 cellular component organization 3 6
GO:0022607 cellular component assembly 4 6
GO:0043933 protein-containing complex organization 4 6
GO:0051259 protein complex oligomerization 6 6
GO:0051260 protein homooligomerization 7 6
GO:0065003 protein-containing complex assembly 5 6
GO:0071840 cellular component organization or biogenesis 2 6
Could not find GO molecular_function term for this entry.

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_C14_Caspase3-7 31 35 PF00656 0.616
CLV_C14_Caspase3-7 413 417 PF00656 0.522
CLV_NRD_NRD_1 205 207 PF00675 0.415
CLV_PCSK_KEX2_1 130 132 PF00082 0.410
CLV_PCSK_KEX2_1 205 207 PF00082 0.415
CLV_PCSK_KEX2_1 7 9 PF00082 0.603
CLV_PCSK_PC1ET2_1 130 132 PF00082 0.410
CLV_PCSK_PC1ET2_1 7 9 PF00082 0.665
CLV_PCSK_SKI1_1 27 31 PF00082 0.717
CLV_Separin_Metazoa 218 222 PF03568 0.402
DEG_SPOP_SBC_1 285 289 PF00917 0.646
DOC_CKS1_1 351 356 PF01111 0.653
DOC_CYCLIN_RxL_1 297 307 PF00134 0.602
DOC_CYCLIN_yCln2_LP_2 266 272 PF00134 0.587
DOC_MAPK_DCC_7 436 446 PF00069 0.412
DOC_MAPK_gen_1 181 190 PF00069 0.347
DOC_MAPK_HePTP_8 233 245 PF00069 0.437
DOC_MAPK_MEF2A_6 184 192 PF00069 0.337
DOC_MAPK_MEF2A_6 236 245 PF00069 0.435
DOC_PP1_RVXF_1 242 248 PF00149 0.378
DOC_PP1_SILK_1 456 461 PF00149 0.412
DOC_PP2B_LxvP_1 135 138 PF13499 0.464
DOC_PP2B_LxvP_1 254 257 PF13499 0.615
DOC_PP2B_LxvP_1 266 269 PF13499 0.523
DOC_PP4_FxxP_1 247 250 PF00568 0.457
DOC_USP7_MATH_1 283 287 PF00917 0.588
DOC_USP7_MATH_1 290 294 PF00917 0.635
DOC_USP7_MATH_1 313 317 PF00917 0.629
DOC_USP7_MATH_1 330 334 PF00917 0.547
DOC_WW_Pin1_4 141 146 PF00397 0.447
DOC_WW_Pin1_4 276 281 PF00397 0.641
DOC_WW_Pin1_4 322 327 PF00397 0.647
DOC_WW_Pin1_4 346 351 PF00397 0.776
DOC_WW_Pin1_4 35 40 PF00397 0.588
DOC_WW_Pin1_4 359 364 PF00397 0.561
DOC_WW_Pin1_4 378 383 PF00397 0.626
DOC_WW_Pin1_4 397 402 PF00397 0.639
DOC_WW_Pin1_4 60 65 PF00397 0.299
LIG_14-3-3_CanoR_1 206 212 PF00244 0.375
LIG_14-3-3_CanoR_1 221 229 PF00244 0.390
LIG_BIR_III_4 467 471 PF00653 0.606
LIG_BRCT_BRCA1_1 324 328 PF00533 0.680
LIG_EVH1_2 442 446 PF00568 0.393
LIG_FHA_1 156 162 PF00498 0.391
LIG_FHA_1 165 171 PF00498 0.398
LIG_FHA_1 214 220 PF00498 0.387
LIG_FHA_1 240 246 PF00498 0.519
LIG_FHA_1 286 292 PF00498 0.637
LIG_FHA_1 459 465 PF00498 0.476
LIG_FHA_2 36 42 PF00498 0.554
LIG_LIR_Apic_2 246 250 PF02991 0.506
LIG_LIR_Gen_1 72 82 PF02991 0.461
LIG_LIR_Gen_1 93 102 PF02991 0.361
LIG_LIR_LC3C_4 112 116 PF02991 0.299
LIG_LIR_Nem_3 72 78 PF02991 0.340
LIG_LIR_Nem_3 93 98 PF02991 0.503
LIG_MYND_1 268 272 PF01753 0.588
LIG_REV1ctd_RIR_1 423 431 PF16727 0.398
LIG_SH2_CRK 105 109 PF00017 0.299
LIG_SH2_STAT3 235 238 PF00017 0.385
LIG_SH2_STAT5 101 104 PF00017 0.358
LIG_SH2_STAT5 213 216 PF00017 0.391
LIG_SH3_3 247 253 PF00018 0.531
LIG_SH3_3 266 272 PF00018 0.690
LIG_SH3_3 295 301 PF00018 0.569
LIG_SH3_3 351 357 PF00018 0.671
LIG_SH3_3 395 401 PF00018 0.583
LIG_SH3_3 406 412 PF00018 0.564
LIG_SH3_3 437 443 PF00018 0.425
LIG_SUMO_SIM_anti_2 112 120 PF11976 0.299
LIG_SUMO_SIM_anti_2 41 47 PF11976 0.299
LIG_SUMO_SIM_anti_2 454 463 PF11976 0.407
LIG_SUMO_SIM_par_1 112 120 PF11976 0.299
LIG_SUMO_SIM_par_1 302 307 PF11976 0.630
LIG_SUMO_SIM_par_1 406 411 PF11976 0.576
LIG_WRC_WIRS_1 422 427 PF05994 0.373
MOD_CDK_SPxxK_3 35 42 PF00069 0.561
MOD_CK1_1 286 292 PF00069 0.592
MOD_CK1_1 346 352 PF00069 0.660
MOD_CK1_1 362 368 PF00069 0.542
MOD_CK1_1 384 390 PF00069 0.624
MOD_CK1_1 454 460 PF00069 0.399
MOD_CK1_1 62 68 PF00069 0.299
MOD_CK2_1 234 240 PF00069 0.386
MOD_CK2_1 314 320 PF00069 0.600
MOD_Cter_Amidation 5 8 PF01082 0.681
MOD_GlcNHglycan 11 15 PF01048 0.677
MOD_GlcNHglycan 223 226 PF01048 0.512
MOD_GlcNHglycan 257 260 PF01048 0.598
MOD_GlcNHglycan 316 319 PF01048 0.654
MOD_GlcNHglycan 332 335 PF01048 0.546
MOD_GlcNHglycan 368 371 PF01048 0.690
MOD_GlcNHglycan 383 386 PF01048 0.679
MOD_GlcNHglycan 391 394 PF01048 0.603
MOD_GlcNHglycan 453 456 PF01048 0.392
MOD_GlcNHglycan 464 467 PF01048 0.473
MOD_GSK3_1 164 171 PF00069 0.394
MOD_GSK3_1 255 262 PF00069 0.624
MOD_GSK3_1 272 279 PF00069 0.604
MOD_GSK3_1 286 293 PF00069 0.525
MOD_GSK3_1 345 352 PF00069 0.635
MOD_GSK3_1 355 362 PF00069 0.641
MOD_GSK3_1 366 373 PF00069 0.709
MOD_GSK3_1 377 384 PF00069 0.600
MOD_GSK3_1 454 461 PF00069 0.452
MOD_GSK3_1 48 55 PF00069 0.299
MOD_GSK3_1 56 63 PF00069 0.299
MOD_N-GLC_1 283 288 PF02516 0.548
MOD_N-GLC_1 313 318 PF02516 0.740
MOD_NEK2_1 174 179 PF00069 0.342
MOD_NEK2_1 22 27 PF00069 0.518
MOD_NEK2_1 274 279 PF00069 0.650
MOD_NEK2_1 291 296 PF00069 0.710
MOD_NEK2_1 343 348 PF00069 0.662
MOD_NEK2_1 366 371 PF00069 0.691
MOD_NEK2_1 446 451 PF00069 0.376
MOD_NEK2_1 459 464 PF00069 0.423
MOD_NEK2_1 56 61 PF00069 0.299
MOD_NEK2_2 421 426 PF00069 0.373
MOD_PIKK_1 234 240 PF00454 0.386
MOD_PK_1 460 466 PF00069 0.438
MOD_PKA_2 22 28 PF00069 0.622
MOD_PKB_1 8 16 PF00069 0.670
MOD_Plk_1 239 245 PF00069 0.361
MOD_Plk_1 306 312 PF00069 0.642
MOD_Plk_1 415 421 PF00069 0.526
MOD_Plk_4 136 142 PF00069 0.481
MOD_Plk_4 174 180 PF00069 0.338
MOD_Plk_4 292 298 PF00069 0.638
MOD_Plk_4 421 427 PF00069 0.374
MOD_Plk_4 454 460 PF00069 0.399
MOD_Plk_4 62 68 PF00069 0.299
MOD_ProDKin_1 141 147 PF00069 0.441
MOD_ProDKin_1 276 282 PF00069 0.637
MOD_ProDKin_1 322 328 PF00069 0.651
MOD_ProDKin_1 346 352 PF00069 0.777
MOD_ProDKin_1 35 41 PF00069 0.573
MOD_ProDKin_1 359 365 PF00069 0.562
MOD_ProDKin_1 378 384 PF00069 0.626
MOD_ProDKin_1 397 403 PF00069 0.641
MOD_ProDKin_1 60 66 PF00069 0.299
MOD_SUMO_for_1 129 132 PF00179 0.395
TRG_DiLeu_BaLyEn_6 398 403 PF01217 0.638
TRG_ER_diArg_1 204 206 PF00400 0.374
TRG_ER_diArg_1 434 437 PF00400 0.409
TRG_Pf-PMV_PEXEL_1 341 345 PF00026 0.678

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N0P854 Leptomonas seymouri 60% 96%
A4I3E4 Leishmania infantum 100% 100%
E9AZN1 Leishmania mexicana (strain MHOM/GT/2001/U1103) 95% 100%
Q4Q8K0 Leishmania major 98% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS