Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X184_LEIDO

TriTrypDb:

LdBPK_280340.1 , LdCL_280009100 , LDHU3_28.0530

Length:

456

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 3
NetGPI	no	yes: 0, no: 3

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X184

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X184

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	162	166	PF00656	0.753
CLV_C14_Caspase3-7	285	289	PF00656	0.701
CLV_C14_Caspase3-7	377	381	PF00656	0.712
CLV_MEL_PAP_1	395	401	PF00089	0.687
CLV_NRD_NRD_1	205	207	PF00675	0.731
CLV_NRD_NRD_1	278	280	PF00675	0.764
CLV_NRD_NRD_1	341	343	PF00675	0.655
CLV_NRD_NRD_1	54	56	PF00675	0.682
CLV_PCSK_KEX2_1	205	207	PF00082	0.731
CLV_PCSK_KEX2_1	278	280	PF00082	0.704
CLV_PCSK_KEX2_1	341	343	PF00082	0.655
CLV_PCSK_KEX2_1	54	56	PF00082	0.682
CLV_PCSK_SKI1_1	237	241	PF00082	0.565
CLV_PCSK_SKI1_1	257	261	PF00082	0.371
CLV_PCSK_SKI1_1	278	282	PF00082	0.720
CLV_PCSK_SKI1_1	307	311	PF00082	0.720
CLV_PCSK_SKI1_1	73	77	PF00082	0.676
DEG_COP1_1	161	172	PF00400	0.755
DEG_SPOP_SBC_1	297	301	PF00917	0.714
DOC_CDC14_PxL_1	238	246	PF14671	0.580
DOC_CKS1_1	169	174	PF01111	0.761
DOC_CYCLIN_RxL_1	205	216	PF00134	0.752
DOC_CYCLIN_yCln2_LP_2	222	228	PF00134	0.742
DOC_CYCLIN_yCln2_LP_2	27	33	PF00134	0.574
DOC_CYCLIN_yCln2_LP_2	309	315	PF00134	0.681
DOC_MAPK_gen_1	137	144	PF00069	0.661
DOC_MAPK_gen_1	205	212	PF00069	0.756
DOC_MAPK_gen_1	284	292	PF00069	0.702
DOC_MAPK_MEF2A_6	257	265	PF00069	0.650
DOC_MAPK_MEF2A_6	403	410	PF00069	0.678
DOC_PP1_RVXF_1	235	241	PF00149	0.566
DOC_PP2B_LxvP_1	155	158	PF13499	0.718
DOC_PP2B_LxvP_1	239	242	PF13499	0.640
DOC_PP2B_LxvP_1	27	30	PF13499	0.661
DOC_USP7_MATH_1	17	21	PF00917	0.568
DOC_USP7_MATH_1	199	203	PF00917	0.718
DOC_USP7_MATH_1	297	301	PF00917	0.714
DOC_USP7_MATH_1	35	39	PF00917	0.584
DOC_USP7_MATH_1	391	395	PF00917	0.669
DOC_WW_Pin1_4	168	173	PF00397	0.700
DOC_WW_Pin1_4	197	202	PF00397	0.756
DOC_WW_Pin1_4	59	64	PF00397	0.631
LIG_14-3-3_CanoR_1	137	143	PF00244	0.572
LIG_14-3-3_CanoR_1	208	213	PF00244	0.657
LIG_14-3-3_CanoR_1	257	262	PF00244	0.674
LIG_14-3-3_CanoR_1	295	303	PF00244	0.638
LIG_14-3-3_CanoR_1	358	367	PF00244	0.691
LIG_14-3-3_CanoR_1	54	64	PF00244	0.699
LIG_14-3-3_CanoR_1	67	77	PF00244	0.504
LIG_Actin_WH2_2	38	56	PF00022	0.666
LIG_Actin_WH2_2	86	102	PF00022	0.573
LIG_APCC_ABBA_1	21	26	PF00400	0.605
LIG_APCC_ABBAyCdc20_2	223	229	PF00400	0.741
LIG_BIR_II_1	1	5	PF00653	0.680
LIG_deltaCOP1_diTrp_1	129	138	PF00928	0.608
LIG_EH1_1	232	240	PF00400	0.660
LIG_eIF4E_1	227	233	PF01652	0.715
LIG_FHA_1	100	106	PF00498	0.620
LIG_FHA_1	244	250	PF00498	0.647
LIG_FHA_1	251	257	PF00498	0.608
LIG_FHA_1	258	264	PF00498	0.543
LIG_FHA_1	347	353	PF00498	0.546
LIG_FHA_1	46	52	PF00498	0.635
LIG_FHA_2	105	111	PF00498	0.646
LIG_FHA_2	300	306	PF00498	0.703
LIG_FHA_2	331	337	PF00498	0.571
LIG_GBD_Chelix_1	434	442	PF00786	0.678
LIG_LIR_Gen_1	22	31	PF02991	0.556
LIG_LIR_Gen_1	347	357	PF02991	0.547
LIG_LIR_Gen_1	412	421	PF02991	0.655
LIG_LIR_Nem_3	151	155	PF02991	0.654
LIG_LIR_Nem_3	22	27	PF02991	0.527
LIG_LIR_Nem_3	231	236	PF02991	0.676
LIG_LIR_Nem_3	412	416	PF02991	0.702
LIG_SH2_STAP1	213	217	PF00017	0.739
LIG_SH2_STAP1	245	249	PF00017	0.707
LIG_SH2_STAP1	348	352	PF00017	0.616
LIG_SH2_STAP1	445	449	PF00017	0.634
LIG_SH2_STAT3	227	230	PF00017	0.730
LIG_SH2_STAT5	227	230	PF00017	0.730
LIG_SH2_STAT5	245	248	PF00017	0.709
LIG_SH2_STAT5	348	351	PF00017	0.623
LIG_SH2_STAT5	77	80	PF00017	0.698
LIG_SH3_3	166	172	PF00018	0.631
LIG_SH3_3	321	327	PF00018	0.666
LIG_Sin3_3	252	259	PF02671	0.701
LIG_SUMO_SIM_anti_2	288	294	PF11976	0.691
LIG_SUMO_SIM_anti_2	407	412	PF11976	0.671
LIG_SUMO_SIM_anti_2	48	53	PF11976	0.637
LIG_SUMO_SIM_par_1	101	107	PF11976	0.622
LIG_SUMO_SIM_par_1	208	214	PF11976	0.753
LIG_SUMO_SIM_par_1	43	50	PF11976	0.655
LIG_TRAF2_1	394	397	PF00917	0.676
LIG_Vh1_VBS_1	352	370	PF01044	0.679
LIG_WRC_WIRS_1	410	415	PF05994	0.662
MOD_CK1_1	161	167	PF00069	0.742
MOD_CK1_1	299	305	PF00069	0.593
MOD_CK1_1	328	334	PF00069	0.715
MOD_CK1_1	7	13	PF00069	0.693
MOD_CK2_1	299	305	PF00069	0.622
MOD_CK2_1	37	43	PF00069	0.688
MOD_CK2_1	390	396	PF00069	0.707
MOD_CK2_1	55	61	PF00069	0.693
MOD_GlcNHglycan	181	184	PF01048	0.690
MOD_GlcNHglycan	197	200	PF01048	0.661
MOD_GlcNHglycan	214	218	PF01048	0.736
MOD_GlcNHglycan	37	40	PF01048	0.596
MOD_GlcNHglycan	377	380	PF01048	0.713
MOD_GlcNHglycan	431	434	PF01048	0.682
MOD_GlcNHglycan	93	96	PF01048	0.681
MOD_GSK3_1	195	202	PF00069	0.646
MOD_GSK3_1	213	220	PF00069	0.737
MOD_GSK3_1	299	306	PF00069	0.508
MOD_GSK3_1	33	40	PF00069	0.590
MOD_GSK3_1	55	62	PF00069	0.650
MOD_LATS_1	323	329	PF00433	0.682
MOD_N-GLC_1	7	12	PF02516	0.725
MOD_NEK2_1	128	133	PF00069	0.603
MOD_NEK2_1	138	143	PF00069	0.522
MOD_NEK2_1	303	308	PF00069	0.533
MOD_NEK2_1	6	11	PF00069	0.747
MOD_NEK2_1	66	71	PF00069	0.663
MOD_NEK2_1	91	96	PF00069	0.673
MOD_PIKK_1	217	223	PF00454	0.666
MOD_PKA_2	138	144	PF00069	0.626
MOD_PKA_2	268	274	PF00069	0.754
MOD_PKA_2	283	289	PF00069	0.664
MOD_PKA_2	66	72	PF00069	0.721
MOD_PKB_1	206	214	PF00069	0.753
MOD_Plk_1	128	134	PF00069	0.625
MOD_Plk_1	346	352	PF00069	0.547
MOD_Plk_2-3	104	110	PF00069	0.599
MOD_Plk_2-3	404	410	PF00069	0.673
MOD_Plk_4	128	134	PF00069	0.606
MOD_Plk_4	19	25	PF00069	0.539
MOD_Plk_4	199	205	PF00069	0.753
MOD_Plk_4	208	214	PF00069	0.618
MOD_Plk_4	37	43	PF00069	0.609
MOD_Plk_4	47	53	PF00069	0.485
MOD_Plk_4	73	79	PF00069	0.680
MOD_ProDKin_1	168	174	PF00069	0.700
MOD_ProDKin_1	197	203	PF00069	0.755
MOD_ProDKin_1	59	65	PF00069	0.635
MOD_SUMO_for_1	359	362	PF00179	0.651
MOD_SUMO_rev_2	299	309	PF00179	0.595
TRG_DiLeu_BaEn_1	305	310	PF01217	0.714
TRG_DiLeu_BaLyEn_6	70	75	PF01217	0.686
TRG_ENDOCYTIC_2	313	316	PF00928	0.632
TRG_ER_diArg_1	144	147	PF00400	0.570
TRG_ER_diArg_1	186	189	PF00400	0.749
TRG_ER_diArg_1	204	206	PF00400	0.548
TRG_ER_diArg_1	277	279	PF00400	0.705
TRG_ER_diArg_1	341	343	PF00400	0.655
TRG_ER_diArg_1	53	55	PF00400	0.674
TRG_NES_CRM1_1	231	243	PF08389	0.616
TRG_Pf-PMV_PEXEL_1	279	283	PF00026	0.760
TRG_Pf-PMV_PEXEL_1	341	346	PF00026	0.646

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1I4P0	Leptomonas seymouri	37%	99%
A4I3A6	Leishmania infantum	99%	100%