LeishMANIAdb
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Ribosomal protein L11, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
Ribosomal protein L11, putative
Gene product:
ribosomal protein L11, putative
Species:
Leishmania donovani
UniProt:
A0A3S7X0Z8_LEIDO
TriTrypDb:
LdBPK_272140.1 , LdCL_270028700 , LDHU3_27.3260
Length:
345

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 0, no: 12
NetGPI no yes: 0, no: 12
Cellular components
Term Name Level Count
GO:0005840 ribosome 5 12
GO:0032991 protein-containing complex 1 13
GO:0043226 organelle 2 12
GO:0043228 non-membrane-bounded organelle 3 12
GO:0043229 intracellular organelle 3 12
GO:0043232 intracellular non-membrane-bounded organelle 4 12
GO:0110165 cellular anatomical entity 1 13
GO:1990904 ribonucleoprotein complex 2 13
GO:0000315 organellar large ribosomal subunit 5 1
GO:0005737 cytoplasm 2 1
GO:0005762 mitochondrial large ribosomal subunit 3 1
GO:0015934 large ribosomal subunit 4 1
GO:0044391 ribosomal subunit 3 1
GO:0098798 mitochondrial protein-containing complex 2 1

Expansion

Sequence features

A0A3S7X0Z8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X0Z8

PDB structure(s): 7aih_E , 7am2_E , 7ane_E

Function

Biological processes
Term Name Level Count
GO:0006412 translation 4 13
GO:0006518 peptide metabolic process 4 13
GO:0006807 nitrogen compound metabolic process 2 13
GO:0008152 metabolic process 1 13
GO:0009058 biosynthetic process 2 13
GO:0009059 macromolecule biosynthetic process 4 13
GO:0009987 cellular process 1 13
GO:0019538 protein metabolic process 3 13
GO:0034641 cellular nitrogen compound metabolic process 3 13
GO:0034645 obsolete cellular macromolecule biosynthetic process 4 13
GO:0043043 peptide biosynthetic process 5 13
GO:0043170 macromolecule metabolic process 3 13
GO:0043603 amide metabolic process 3 13
GO:0043604 amide biosynthetic process 4 13
GO:0044237 cellular metabolic process 2 13
GO:0044238 primary metabolic process 2 13
GO:0044249 cellular biosynthetic process 3 13
GO:0044260 obsolete cellular macromolecule metabolic process 3 13
GO:0044271 cellular nitrogen compound biosynthetic process 4 13
GO:0071704 organic substance metabolic process 2 13
GO:1901564 organonitrogen compound metabolic process 3 13
GO:1901566 organonitrogen compound biosynthetic process 4 13
GO:1901576 organic substance biosynthetic process 3 13
Molecular functions
Term Name Level Count
GO:0003735 structural constituent of ribosome 2 13
GO:0005198 structural molecule activity 1 13
GO:0003676 nucleic acid binding 3 1
GO:0003723 RNA binding 4 1
GO:0005488 binding 1 1
GO:0019843 rRNA binding 5 1
GO:0070180 large ribosomal subunit rRNA binding 6 1
GO:0097159 organic cyclic compound binding 2 1
GO:1901363 heterocyclic compound binding 2 1

Putative motif mimicry

Leishmania From To Domain/Motif Score
CLV_NRD_NRD_1 129 131 PF00675 0.323
CLV_NRD_NRD_1 178 180 PF00675 0.323
CLV_NRD_NRD_1 185 187 PF00675 0.323
CLV_NRD_NRD_1 217 219 PF00675 0.538
CLV_NRD_NRD_1 289 291 PF00675 0.456
CLV_NRD_NRD_1 3 5 PF00675 0.602
CLV_PCSK_FUR_1 130 134 PF00082 0.323
CLV_PCSK_FUR_1 176 180 PF00082 0.323
CLV_PCSK_KEX2_1 132 134 PF00082 0.323
CLV_PCSK_KEX2_1 178 180 PF00082 0.323
CLV_PCSK_KEX2_1 185 187 PF00082 0.323
CLV_PCSK_KEX2_1 289 291 PF00082 0.456
CLV_PCSK_KEX2_1 3 5 PF00082 0.602
CLV_PCSK_PC1ET2_1 132 134 PF00082 0.323
CLV_PCSK_PC7_1 285 291 PF00082 0.451
CLV_PCSK_SKI1_1 203 207 PF00082 0.470
CLV_PCSK_SKI1_1 275 279 PF00082 0.626
CLV_PCSK_SKI1_1 299 303 PF00082 0.436
CLV_PCSK_SKI1_1 307 311 PF00082 0.415
CLV_PCSK_SKI1_1 339 343 PF00082 0.674
CLV_PCSK_SKI1_1 36 40 PF00082 0.411
CLV_PCSK_SKI1_1 47 51 PF00082 0.412
CLV_PCSK_SKI1_1 61 65 PF00082 0.323
CLV_PCSK_SKI1_1 8 12 PF00082 0.661
DEG_Nend_Nbox_1 1 3 PF02207 0.574
DOC_CYCLIN_RxL_1 270 282 PF00134 0.596
DOC_CYCLIN_yClb5_NLxxxL_5 259 268 PF00134 0.522
DOC_MAPK_gen_1 11 19 PF00069 0.535
DOC_MAPK_gen_1 185 191 PF00069 0.323
DOC_MAPK_MEF2A_6 167 175 PF00069 0.450
DOC_MAPK_MEF2A_6 95 104 PF00069 0.323
DOC_MAPK_NFAT4_5 95 103 PF00069 0.450
DOC_PP1_RVXF_1 305 311 PF00149 0.458
DOC_PP4_FxxP_1 26 29 PF00568 0.572
DOC_PP4_FxxP_1 39 42 PF00568 0.408
DOC_SPAK_OSR1_1 54 58 PF12202 0.323
DOC_USP7_UBL2_3 11 15 PF12436 0.628
DOC_USP7_UBL2_3 74 78 PF12436 0.323
DOC_USP7_UBL2_3 91 95 PF12436 0.323
DOC_WW_Pin1_4 197 202 PF00397 0.479
DOC_WW_Pin1_4 299 304 PF00397 0.473
DOC_WW_Pin1_4 340 345 PF00397 0.729
LIG_14-3-3_CanoR_1 13 18 PF00244 0.495
LIG_14-3-3_CanoR_1 3 10 PF00244 0.599
LIG_APCC_ABBA_1 104 109 PF00400 0.323
LIG_APCC_ABBAyCdc20_2 103 109 PF00400 0.323
LIG_BRCT_BRCA1_1 110 114 PF00533 0.391
LIG_BRCT_BRCA1_1 22 26 PF00533 0.578
LIG_BRCT_BRCA1_1 332 336 PF00533 0.440
LIG_CtBP_PxDLS_1 303 307 PF00389 0.458
LIG_FHA_1 134 140 PF00498 0.342
LIG_FHA_1 14 20 PF00498 0.515
LIG_FHA_2 251 257 PF00498 0.575
LIG_FHA_2 300 306 PF00498 0.427
LIG_LIR_Apic_2 23 29 PF02991 0.573
LIG_LIR_Apic_2 37 42 PF02991 0.410
LIG_LIR_Gen_1 71 80 PF02991 0.317
LIG_LIR_Nem_3 121 126 PF02991 0.323
LIG_LIR_Nem_3 164 168 PF02991 0.348
LIG_LIR_Nem_3 169 173 PF02991 0.304
LIG_LIR_Nem_3 71 75 PF02991 0.317
LIG_LYPXL_yS_3 170 173 PF13949 0.336
LIG_Pex14_2 82 86 PF04695 0.323
LIG_PTB_Apo_2 49 56 PF02174 0.394
LIG_REV1ctd_RIR_1 53 62 PF16727 0.323
LIG_SH2_GRB2like 291 294 PF00017 0.444
LIG_SH2_SRC 155 158 PF00017 0.323
LIG_SH2_STAT5 107 110 PF00017 0.335
LIG_SH2_STAT5 112 115 PF00017 0.383
LIG_SH2_STAT5 145 148 PF00017 0.336
LIG_SH2_STAT5 210 213 PF00017 0.550
LIG_SH2_STAT5 291 294 PF00017 0.444
LIG_SH2_STAT5 9 12 PF00017 0.721
LIG_SH3_2 42 47 PF14604 0.417
LIG_SH3_3 165 171 PF00018 0.336
LIG_SH3_3 39 45 PF00018 0.412
LIG_SH3_4 91 98 PF00018 0.323
LIG_SUMO_SIM_anti_2 96 102 PF11976 0.336
LIG_TRAF2_1 302 305 PF00917 0.464
LIG_TYR_ITIM 168 173 PF00017 0.450
LIG_TYR_ITIM 223 228 PF00017 0.499
LIG_UBA3_1 125 132 PF00899 0.336
LIG_UBA3_1 264 270 PF00899 0.507
MOD_CDC14_SPxK_1 200 203 PF00782 0.464
MOD_CDK_SPxK_1 197 203 PF00069 0.465
MOD_CK2_1 250 256 PF00069 0.573
MOD_CK2_1 299 305 PF00069 0.435
MOD_GlcNHglycan 234 237 PF01048 0.545
MOD_GlcNHglycan 4 7 PF01048 0.686
MOD_GSK3_1 193 200 PF00069 0.441
MOD_GSK3_1 269 276 PF00069 0.430
MOD_GSK3_1 335 342 PF00069 0.470
MOD_N-GLC_1 324 329 PF02516 0.580
MOD_N-GLC_2 144 146 PF02516 0.472
MOD_NEK2_1 108 113 PF00069 0.323
MOD_NEK2_1 2 7 PF00069 0.660
MOD_NEK2_1 250 255 PF00069 0.585
MOD_NEK2_1 268 273 PF00069 0.472
MOD_NEK2_2 193 198 PF00069 0.475
MOD_PIKK_1 250 256 PF00454 0.525
MOD_PIKK_1 330 336 PF00454 0.646
MOD_PKA_2 2 8 PF00069 0.651
MOD_Plk_1 108 114 PF00069 0.323
MOD_Plk_4 108 114 PF00069 0.336
MOD_Plk_4 273 279 PF00069 0.500
MOD_ProDKin_1 197 203 PF00069 0.485
MOD_ProDKin_1 299 305 PF00069 0.471
MOD_SUMO_rev_2 28 35 PF00179 0.565
TRG_DiLeu_LyEn_5 234 239 PF01217 0.503
TRG_ENDOCYTIC_2 148 151 PF00928 0.333
TRG_ENDOCYTIC_2 170 173 PF00928 0.327
TRG_ENDOCYTIC_2 225 228 PF00928 0.450
TRG_ER_diArg_1 175 178 PF00400 0.327
TRG_ER_diArg_1 185 187 PF00400 0.315
TRG_ER_diArg_1 2 4 PF00400 0.588
TRG_ER_diArg_1 289 291 PF00400 0.480
TRG_NLS_MonoCore_2 129 134 PF00514 0.323
TRG_NLS_MonoExtC_3 129 135 PF00514 0.323
TRG_NLS_MonoExtN_4 127 134 PF00514 0.323

Homologs

Protein Taxonomy Sequence identity Coverage
A0A0N1IMB3 Leptomonas seymouri 84% 100%
A0A0S4IQP6 Bodo saltans 63% 100%
A0A1X0NR49 Trypanosomatidae 71% 100%
A0A3R7NDU6 Trypanosoma rangeli 72% 100%
A4HFZ9 Leishmania braziliensis 93% 100%
A4I318 Leishmania infantum 99% 100%
C9ZJH2 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 70% 100%
C9ZJI7 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 70% 100%
E9ACT9 Leishmania major 97% 100%
E9AZC8 Leishmania mexicana (strain MHOM/GT/2001/U1103) 97% 100%
V5AS82 Trypanosoma cruzi 72% 100%

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS