Meiotic cell cortex C-terminal pleckstrin homology, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Download

Quick info

Protein:

Gene product:

Meiotic cell cortex C-terminal pleckstrin homology, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X0Z7_LEIDO

TriTrypDb:

LdBPK_272200.1 , LdCL_270029400 , LDHU3_27.3340

Length:

571

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 1
NetGPI	no	yes: 0, no: 1

Cellular components
Term	Name	Level	Count
GO:0005737	cytoplasm	2	2
GO:0005938	cell cortex	3	2
GO:0110165	cellular anatomical entity	1	2

Expansion

Sequence features

A0A3S7X0Z7

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X0Z7

Function

Biological processes
Term	Name	Level	Count
GO:0009987	cellular process	1	2
GO:0032065	maintenance of protein location in cell cortex	4	2
GO:0032507	maintenance of protein location in cell	3	2
GO:0045185	maintenance of protein location	3	2
GO:0051179	localization	1	2
GO:0051235	maintenance of location	2	2
GO:0051651	maintenance of location in cell	2	2

Molecular functions
Term	Name	Level	Count
GO:0005488	binding	1	2
GO:0005543	phospholipid binding	3	2
GO:0008289	lipid binding	2	2

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	462	466	PF00656	0.199
CLV_NRD_NRD_1	100	102	PF00675	0.542
CLV_NRD_NRD_1	152	154	PF00675	0.534
CLV_NRD_NRD_1	18	20	PF00675	0.410
CLV_NRD_NRD_1	196	198	PF00675	0.496
CLV_NRD_NRD_1	273	275	PF00675	0.528
CLV_NRD_NRD_1	284	286	PF00675	0.533
CLV_NRD_NRD_1	338	340	PF00675	0.545
CLV_NRD_NRD_1	344	346	PF00675	0.531
CLV_NRD_NRD_1	360	362	PF00675	0.529
CLV_NRD_NRD_1	364	366	PF00675	0.532
CLV_NRD_NRD_1	428	430	PF00675	0.503
CLV_NRD_NRD_1	469	471	PF00675	0.199
CLV_NRD_NRD_1	52	54	PF00675	0.542
CLV_NRD_NRD_1	529	531	PF00675	0.199
CLV_PCSK_FUR_1	16	20	PF00082	0.403
CLV_PCSK_FUR_1	268	272	PF00082	0.517
CLV_PCSK_FUR_1	358	362	PF00082	0.530
CLV_PCSK_KEX2_1	100	102	PF00082	0.542
CLV_PCSK_KEX2_1	151	153	PF00082	0.527
CLV_PCSK_KEX2_1	16	18	PF00082	0.396
CLV_PCSK_KEX2_1	270	272	PF00082	0.517
CLV_PCSK_KEX2_1	284	286	PF00082	0.533
CLV_PCSK_KEX2_1	338	340	PF00082	0.545
CLV_PCSK_KEX2_1	343	345	PF00082	0.531
CLV_PCSK_KEX2_1	360	362	PF00082	0.529
CLV_PCSK_KEX2_1	364	366	PF00082	0.532
CLV_PCSK_KEX2_1	469	471	PF00082	0.199
CLV_PCSK_KEX2_1	51	53	PF00082	0.549
CLV_PCSK_KEX2_1	531	533	PF00082	0.199
CLV_PCSK_PC1ET2_1	270	272	PF00082	0.517
CLV_PCSK_PC1ET2_1	51	53	PF00082	0.549
CLV_PCSK_PC1ET2_1	531	533	PF00082	0.199
CLV_PCSK_PC7_1	280	286	PF00082	0.531
CLV_PCSK_PC7_1	339	345	PF00082	0.535
CLV_PCSK_PC7_1	360	366	PF00082	0.531
CLV_PCSK_SKI1_1	123	127	PF00082	0.517
CLV_PCSK_SKI1_1	19	23	PF00082	0.437
CLV_PCSK_SKI1_1	531	535	PF00082	0.199
CLV_PCSK_SKI1_1	565	569	PF00082	0.375
DEG_Nend_UBRbox_2	1	3	PF02207	0.435
DEG_SPOP_SBC_1	79	83	PF00917	0.510
DOC_CKS1_1	143	148	PF01111	0.516
DOC_CKS1_1	46	51	PF01111	0.516
DOC_CYCLIN_RxL_1	529	539	PF00134	0.199
DOC_CYCLIN_yCln2_LP_2	179	185	PF00134	0.481
DOC_MAPK_gen_1	426	435	PF00069	0.496
DOC_MAPK_gen_1	530	536	PF00069	0.199
DOC_MAPK_MEF2A_6	426	435	PF00069	0.496
DOC_PP2B_LxvP_1	183	186	PF13499	0.469
DOC_PP2B_LxvP_1	187	190	PF13499	0.494
DOC_PP2B_LxvP_1	433	436	PF13499	0.478
DOC_PP2B_LxvP_1	77	80	PF13499	0.509
DOC_PP4_FxxP_1	132	135	PF00568	0.481
DOC_PP4_FxxP_1	25	28	PF00568	0.518
DOC_PP4_MxPP_1	42	45	PF00568	0.506
DOC_USP7_MATH_1	359	363	PF00917	0.528
DOC_USP7_MATH_1	393	397	PF00917	0.509
DOC_USP7_MATH_1	65	69	PF00917	0.515
DOC_USP7_MATH_1	91	95	PF00917	0.523
DOC_USP7_UBL2_3	459	463	PF12436	0.199
DOC_WW_Pin1_4	116	121	PF00397	0.521
DOC_WW_Pin1_4	131	136	PF00397	0.489
DOC_WW_Pin1_4	142	147	PF00397	0.515
DOC_WW_Pin1_4	156	161	PF00397	0.506
DOC_WW_Pin1_4	241	246	PF00397	0.501
DOC_WW_Pin1_4	327	332	PF00397	0.522
DOC_WW_Pin1_4	388	393	PF00397	0.512
DOC_WW_Pin1_4	40	45	PF00397	0.507
DOC_WW_Pin1_4	414	419	PF00397	0.513
DOC_WW_Pin1_4	61	66	PF00397	0.527
DOC_WW_Pin1_4	80	85	PF00397	0.498
DOC_WW_Pin1_4	87	92	PF00397	0.520
LIG_14-3-3_CanoR_1	100	105	PF00244	0.530
LIG_14-3-3_CanoR_1	106	115	PF00244	0.525
LIG_14-3-3_CanoR_1	151	156	PF00244	0.522
LIG_14-3-3_CanoR_1	176	182	PF00244	0.498
LIG_14-3-3_CanoR_1	191	196	PF00244	0.494
LIG_14-3-3_CanoR_1	403	413	PF00244	0.519
LIG_14-3-3_CanoR_1	445	449	PF00244	0.293
LIG_14-3-3_CanoR_1	66	74	PF00244	0.519
LIG_AP2alpha_2	155	157	PF02296	0.515
LIG_BIR_III_4	37	41	PF00653	0.509
LIG_BRCT_BRCA1_1	166	170	PF00533	0.503
LIG_deltaCOP1_diTrp_1	212	217	PF00928	0.494
LIG_deltaCOP1_diTrp_1	455	460	PF00928	0.199
LIG_DLG_GKlike_1	137	145	PF00625	0.510
LIG_FHA_1	178	184	PF00498	0.489
LIG_FHA_1	251	257	PF00498	0.518
LIG_FHA_1	430	436	PF00498	0.488
LIG_FHA_1	439	445	PF00498	0.370
LIG_FHA_1	519	525	PF00498	0.199
LIG_FHA_2	22	28	PF00498	0.499
LIG_FHA_2	230	236	PF00498	0.502
LIG_FHA_2	444	450	PF00498	0.295
LIG_FHA_2	504	510	PF00498	0.199
LIG_FHA_2	544	550	PF00498	0.199
LIG_LIR_Apic_2	140	146	PF02991	0.513
LIG_LIR_Apic_2	154	160	PF02991	0.515
LIG_LIR_Apic_2	24	28	PF02991	0.515
LIG_LIR_Apic_2	375	380	PF02991	0.494
LIG_LIR_Gen_1	476	486	PF02991	0.199
LIG_LIR_Gen_1	521	527	PF02991	0.199
LIG_LIR_Gen_1	545	555	PF02991	0.199
LIG_LIR_Nem_3	476	482	PF02991	0.199
LIG_LIR_Nem_3	484	489	PF02991	0.199
LIG_LIR_Nem_3	521	526	PF02991	0.199
LIG_LIR_Nem_3	545	551	PF02991	0.199
LIG_PALB2_WD40_1	543	551	PF16756	0.199
LIG_Pex14_1	213	217	PF04695	0.495
LIG_PTB_Apo_2	487	494	PF02174	0.199
LIG_SH2_CRK	143	147	PF00017	0.516
LIG_SH2_CRK	377	381	PF00017	0.493
LIG_SH2_NCK_1	143	147	PF00017	0.516
LIG_SH2_PTP2	523	526	PF00017	0.199
LIG_SH2_SRC	377	380	PF00017	0.490
LIG_SH2_STAT5	188	191	PF00017	0.494
LIG_SH2_STAT5	479	482	PF00017	0.199
LIG_SH2_STAT5	523	526	PF00017	0.199
LIG_SH3_2	199	204	PF14604	0.489
LIG_SH3_3	179	185	PF00018	0.481
LIG_SH3_3	193	199	PF00018	0.492
LIG_SH3_3	26	32	PF00018	0.508
LIG_SH3_3	311	317	PF00018	0.510
LIG_SH3_3	323	329	PF00018	0.529
LIG_SH3_3	38	44	PF00018	0.506
LIG_SH3_3	389	395	PF00018	0.508
LIG_SUMO_SIM_par_1	523	529	PF11976	0.199
LIG_WRC_WIRS_1	22	27	PF05994	0.497
LIG_WW_1	185	188	PF00397	0.484
LIG_WW_2	44	47	PF00397	0.500
MOD_CDC14_SPxK_1	134	137	PF00782	0.488
MOD_CDK_SPK_2	327	332	PF00069	0.522
MOD_CDK_SPK_2	414	419	PF00069	0.513
MOD_CDK_SPK_2	61	66	PF00069	0.527
MOD_CDK_SPxK_1	131	137	PF00069	0.491
MOD_CDK_SPxK_1	45	51	PF00069	0.514
MOD_CDK_SPxxK_3	116	123	PF00069	0.519
MOD_CDK_SPxxK_3	45	52	PF00069	0.519
MOD_CK1_1	164	170	PF00069	0.503
MOD_CK1_1	273	279	PF00069	0.534
MOD_CK1_1	391	397	PF00069	0.507
MOD_CK1_1	402	408	PF00069	0.524
MOD_CK1_1	447	453	PF00069	0.199
MOD_CK1_1	56	62	PF00069	0.537
MOD_CK2_1	21	27	PF00069	0.489
MOD_CK2_1	443	449	PF00069	0.307
MOD_CK2_1	481	487	PF00069	0.199
MOD_CK2_1	509	515	PF00069	0.199
MOD_CK2_1	543	549	PF00069	0.199
MOD_Cter_Amidation	362	365	PF01082	0.531
MOD_GlcNHglycan	108	111	PF01048	0.529
MOD_GlcNHglycan	147	150	PF01048	0.517
MOD_GlcNHglycan	163	166	PF01048	0.505
MOD_GlcNHglycan	290	293	PF01048	0.535
MOD_GlcNHglycan	323	326	PF01048	0.533
MOD_GlcNHglycan	361	364	PF01048	0.529
MOD_GlcNHglycan	385	388	PF01048	0.515
MOD_GlcNHglycan	408	411	PF01048	0.523
MOD_GlcNHglycan	67	70	PF01048	0.518
MOD_GSK3_1	137	144	PF00069	0.509
MOD_GSK3_1	147	154	PF00069	0.523
MOD_GSK3_1	164	171	PF00069	0.504
MOD_GSK3_1	221	228	PF00069	0.493
MOD_GSK3_1	234	241	PF00069	0.502
MOD_GSK3_1	246	253	PF00069	0.523
MOD_GSK3_1	284	291	PF00069	0.534
MOD_GSK3_1	394	401	PF00069	0.524
MOD_GSK3_1	402	409	PF00069	0.524
MOD_GSK3_1	414	421	PF00069	0.516
MOD_GSK3_1	443	450	PF00069	0.303
MOD_GSK3_1	459	466	PF00069	0.199
MOD_GSK3_1	481	488	PF00069	0.199
MOD_GSK3_1	504	511	PF00069	0.199
MOD_GSK3_1	52	59	PF00069	0.537
MOD_GSK3_1	61	68	PF00069	0.524
MOD_GSK3_1	87	94	PF00069	0.521
MOD_NEK2_1	141	146	PF00069	0.515
MOD_NEK2_1	246	251	PF00069	0.522
MOD_NEK2_1	481	486	PF00069	0.199
MOD_NEK2_1	493	498	PF00069	0.199
MOD_NEK2_1	526	531	PF00069	0.199
MOD_NEK2_1	86	91	PF00069	0.520
MOD_PIKK_1	246	252	PF00454	0.522
MOD_PIKK_1	254	260	PF00454	0.519
MOD_PIKK_1	394	400	PF00454	0.523
MOD_PIKK_1	56	62	PF00454	0.537
MOD_PK_1	100	106	PF00069	0.531
MOD_PK_1	191	197	PF00069	0.497
MOD_PK_1	463	469	PF00069	0.199
MOD_PKA_1	100	106	PF00069	0.531
MOD_PKA_1	151	157	PF00069	0.523
MOD_PKA_1	270	276	PF00069	0.524
MOD_PKA_1	284	290	PF00069	0.535
MOD_PKA_1	429	435	PF00069	0.497
MOD_PKA_1	52	58	PF00069	0.538
MOD_PKA_2	100	106	PF00069	0.531
MOD_PKA_2	151	157	PF00069	0.523
MOD_PKA_2	177	183	PF00069	0.496
MOD_PKA_2	250	256	PF00069	0.520
MOD_PKA_2	270	276	PF00069	0.524
MOD_PKA_2	283	289	PF00069	0.534
MOD_PKA_2	359	365	PF00069	0.530
MOD_PKA_2	402	408	PF00069	0.524
MOD_PKA_2	418	424	PF00069	0.510
MOD_PKA_2	444	450	PF00069	0.295
MOD_PKA_2	52	58	PF00069	0.538
MOD_PKA_2	65	71	PF00069	0.515
MOD_PKB_1	234	242	PF00069	0.503
MOD_PKB_1	371	379	PF00069	0.504
MOD_Plk_1	508	514	PF00069	0.199
MOD_Plk_2-3	509	515	PF00069	0.199
MOD_Plk_4	475	481	PF00069	0.199
MOD_Plk_4	518	524	PF00069	0.199
MOD_Plk_4	543	549	PF00069	0.199
MOD_ProDKin_1	116	122	PF00069	0.518
MOD_ProDKin_1	131	137	PF00069	0.491
MOD_ProDKin_1	142	148	PF00069	0.515
MOD_ProDKin_1	156	162	PF00069	0.499
MOD_ProDKin_1	241	247	PF00069	0.503
MOD_ProDKin_1	327	333	PF00069	0.524
MOD_ProDKin_1	388	394	PF00069	0.513
MOD_ProDKin_1	40	46	PF00069	0.508
MOD_ProDKin_1	414	420	PF00069	0.514
MOD_ProDKin_1	61	67	PF00069	0.527
MOD_ProDKin_1	80	86	PF00069	0.503
MOD_ProDKin_1	87	93	PF00069	0.522
TRG_DiLeu_BaLyEn_6	112	117	PF01217	0.522
TRG_ENDOCYTIC_2	479	482	PF00928	0.199
TRG_ENDOCYTIC_2	522	525	PF00928	0.199
TRG_ER_diArg_1	105	108	PF00400	0.526
TRG_ER_diArg_1	151	153	PF00400	0.527
TRG_ER_diArg_1	16	19	PF00400	0.399
TRG_ER_diArg_1	176	179	PF00400	0.503
TRG_ER_diArg_1	343	345	PF00400	0.531
TRG_ER_diArg_1	358	361	PF00400	0.532
TRG_ER_diArg_1	364	367	PF00400	0.532
TRG_ER_diArg_1	469	471	PF00400	0.199
TRG_ER_diArg_1	530	533	PF00400	0.199
TRG_NLS_MonoExtN_4	271	278	PF00514	0.530
TRG_NLS_MonoExtN_4	49	55	PF00514	0.535