Hypothetical_protein_conserved

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein, conserved

Species:

Leishmania donovani

UniProt:

A0A3S7X0X1_LEIDO

TriTrypDb:

LdBPK_271930.1 , LdCL_270026500 , LDHU3_27.2910

Length:

251

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 4
NetGPI	no	yes: 0, no: 4

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X0X1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X0X1

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	200	204	PF00656	0.682
CLV_NRD_NRD_1	49	51	PF00675	0.657
CLV_PCSK_FUR_1	128	132	PF00082	0.668
CLV_PCSK_KEX2_1	130	132	PF00082	0.672
CLV_PCSK_KEX2_1	49	51	PF00082	0.657
CLV_PCSK_PC1ET2_1	130	132	PF00082	0.672
CLV_PCSK_SKI1_1	130	134	PF00082	0.604
CLV_PCSK_SKI1_1	50	54	PF00082	0.805
DEG_APCC_DBOX_1	163	171	PF00400	0.667
DOC_PP2B_LxvP_1	15	18	PF13499	0.747
DOC_USP7_MATH_1	178	182	PF00917	0.707
DOC_USP7_MATH_1	61	65	PF00917	0.757
DOC_USP7_MATH_1	89	93	PF00917	0.806
DOC_USP7_MATH_1	95	99	PF00917	0.646
DOC_WW_Pin1_4	206	211	PF00397	0.740
DOC_WW_Pin1_4	59	64	PF00397	0.781
DOC_WW_Pin1_4	77	82	PF00397	0.809
DOC_WW_Pin1_4	8	13	PF00397	0.813
LIG_14-3-3_CanoR_1	123	132	PF00244	0.506
LIG_14-3-3_CanoR_1	49	53	PF00244	0.668
LIG_APCC_ABBAyCdc20_2	49	55	PF00400	0.675
LIG_CtBP_PxDLS_1	18	22	PF00389	0.603
LIG_FHA_2	106	112	PF00498	0.647
LIG_HCF-1_HBM_1	219	222	PF13415	0.806
LIG_LIR_Apic_2	219	225	PF02991	0.804
LIG_PDZ_Class_1	246	251	PF00595	0.657
LIG_SH2_CRK	222	226	PF00017	0.808
LIG_SH2_CRK	74	78	PF00017	0.615
LIG_SH2_NCK_1	34	38	PF00017	0.641
LIG_SH2_SRC	34	37	PF00017	0.642
LIG_SH2_STAP1	149	153	PF00017	0.655
LIG_SH2_STAT3	115	118	PF00017	0.627
LIG_SH2_STAT5	115	118	PF00017	0.627
LIG_SH2_STAT5	230	233	PF00017	0.800
LIG_SH2_STAT5	30	33	PF00017	0.697
LIG_SH3_3	2	8	PF00018	0.636
LIG_SH3_3	226	232	PF00018	0.800
LIG_SH3_3	70	76	PF00018	0.810
LIG_SH3_3	88	94	PF00018	0.519
LIG_SUMO_SIM_par_1	75	80	PF11976	0.681
MOD_CDK_SPxxK_3	59	66	PF00069	0.827
MOD_CK1_1	20	26	PF00069	0.631
MOD_GlcNHglycan	145	148	PF01048	0.652
MOD_GlcNHglycan	222	225	PF01048	0.763
MOD_GlcNHglycan	239	242	PF01048	0.527
MOD_GlcNHglycan	85	89	PF01048	0.806
MOD_GlcNHglycan	91	94	PF01048	0.693
MOD_GlcNHglycan	97	100	PF01048	0.457
MOD_GSK3_1	172	179	PF00069	0.593
MOD_GSK3_1	233	240	PF00069	0.741
MOD_GSK3_1	55	62	PF00069	0.741
MOD_N-GLC_1	176	181	PF02516	0.687
MOD_N-GLC_1	41	46	PF02516	0.776
MOD_NEK2_1	41	46	PF00069	0.638
MOD_PIKK_1	61	67	PF00454	0.756
MOD_PKA_1	130	136	PF00069	0.670
MOD_PKA_2	130	136	PF00069	0.670
MOD_PKA_2	48	54	PF00069	0.672
MOD_Plk_1	140	146	PF00069	0.585
MOD_Plk_1	41	47	PF00069	0.713
MOD_Plk_2-3	105	111	PF00069	0.649
MOD_Plk_4	105	111	PF00069	0.594
MOD_Plk_4	180	186	PF00069	0.621
MOD_ProDKin_1	206	212	PF00069	0.739
MOD_ProDKin_1	59	65	PF00069	0.783
MOD_ProDKin_1	77	83	PF00069	0.808
MOD_ProDKin_1	8	14	PF00069	0.810
TRG_ENDOCYTIC_2	74	77	PF00928	0.614
TRG_ER_diArg_1	164	167	PF00400	0.666
TRG_Pf-PMV_PEXEL_1	158	163	PF00026	0.653

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A4I308	Leishmania infantum	99%	100%
E9ADI1	Leishmania major	87%	100%
E9AZA5	Leishmania mexicana (strain MHOM/GT/2001/U1103)	85%	100%