LeishMANIAdb
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GTP binding protein, putative

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:
GTP binding protein, putative
Gene product:
GTP binding protein, putative
Species:
Leishmania donovani
UniProt:
A0A3S7X0V3_LEIDO
TriTrypDb:
LdBPK_271730.1 , LdCL_270024500 , LDHU3_27.2670
Length:
372

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 0
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 no yes: 1, no: 10
NetGPI no yes: 0, no: 11
Cellular components
TermNameLevelCount
GO:0005737 cytoplasm 2 1
GO:0110165 cellular anatomical entity 1 1
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Expansion

Sequence features

A0A3S7X0V3
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X0V3

Function

Could not find GO biological_process term for this entry.
Molecular functions
TermNameLevelCount
GO:0000166 nucleotide binding 3 12
GO:0003824 catalytic activity 1 12
GO:0005488 binding 1 12
GO:0005524 ATP binding 5 12
GO:0005525 GTP binding 5 12
GO:0016462 pyrophosphatase activity 5 12
GO:0016787 hydrolase activity 2 12
GO:0016817 hydrolase activity, acting on acid anhydrides 3 12
GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 4 12
GO:0016887 ATP hydrolysis activity 7 12
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Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_NRD_NRD_1 11 13 PF00675 0.336
CLV_NRD_NRD_1 152 154 PF00675 0.400
CLV_PCSK_KEX2_1 10 12 PF00082 0.387
CLV_PCSK_KEX2_1 150 152 PF00082 0.422
CLV_PCSK_KEX2_1 170 172 PF00082 0.193
CLV_PCSK_PC1ET2_1 150 152 PF00082 0.474
CLV_PCSK_PC1ET2_1 170 172 PF00082 0.351
CLV_PCSK_SKI1_1 157 161 PF00082 0.531
CLV_PCSK_SKI1_1 196 200 PF00082 0.392
CLV_PCSK_SKI1_1 219 223 PF00082 0.483
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PD45 Leptomonas seymouri 81% 100%
A0A0N1PG70 Leptomonas seymouri 34% 95%
A0A0S4JQA1 Bodo saltans 32% 95%
A0A0S4JQX4 Bodo saltans 63% 100%
A0A1X0NR20 Trypanosomatidae 32% 94%
A0A1X0NSW3 Trypanosomatidae 64% 100%
A0A3R7MAR4 Trypanosoma rangeli 32% 94%
A0A3R7MNI8 Trypanosoma rangeli 67% 100%
A0A3S7X112 Leishmania donovani 35% 100%
A0JPJ7 Rattus norvegicus 35% 94%
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Download

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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS