Histone H1

Quick info Localization Expansion Sequence features Structure Function Putative motif mimicry Homologs Download

Quick info

Protein:

Histone H1

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3S7X0Q1_LEIDO

TriTrypDb:

LdCL_270017700

Length:

102

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 2
NetGPI	no	yes: 0, no: 2

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Cellular components
Term	Name	Level	Count
GO:0000786	nucleosome	3	3
GO:0032991	protein-containing complex	1	3
GO:0032993	protein-DNA complex	2	3
GO:0044815	DNA packaging complex	2	3

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Expansion

Sequence features

A0A3S7X0Q1

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X0Q1

Function

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Biological processes
Term	Name	Level	Count
GO:0006325	chromatin organization	4	3
GO:0006334	nucleosome assembly	7	3
GO:0006338	chromatin remodeling	5	3
GO:0009987	cellular process	1	3
GO:0016043	cellular component organization	3	3
GO:0022607	cellular component assembly	4	3
GO:0034728	nucleosome organization	6	3
GO:0043933	protein-containing complex organization	4	3
GO:0065003	protein-containing complex assembly	5	3
GO:0065004	protein-DNA complex assembly	6	3

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Molecular functions
Term	Name	Level	Count
GO:0003676	nucleic acid binding	3	3
GO:0003677	DNA binding	4	3
GO:0005198	structural molecule activity	1	3
GO:0005488	binding	1	3
GO:0030527	structural constituent of chromatin	2	3
GO:0097159	organic cyclic compound binding	2	3
GO:1901363	heterocyclic compound binding	2	3

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Putative motif mimicry

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Leishmania	From	To	Domain/Motif	Score
CLV_NRD_NRD_1	49	51	PF00675	0.637
CLV_PCSK_SKI1_1	51	55	PF00082	0.744
CLV_PCSK_SKI1_1	57	61	PF00082	0.668
CLV_PCSK_SKI1_1	65	69	PF00082	0.559
CLV_PCSK_SKI1_1	73	77	PF00082	0.524
CLV_PCSK_SKI1_1	81	85	PF00082	0.523
CLV_PCSK_SKI1_1	89	93	PF00082	0.511
DOC_CKS1_1	52	57	PF01111	0.743
DOC_USP7_UBL2_3	27	31	PF12436	0.735
DOC_USP7_UBL2_3	32	36	PF12436	0.663

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Homologs

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Protein	Taxonomy	Sequence identity	Coverage
A4I2S4	Leishmania infantum	98%	100%

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