RING-H2 zinc finger/Anaphase-promoting complex subunit 11 RING-H2 finger/Ring finger domain containing protein, putative

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

RING-H2 zinc finger, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X0M5_LEIDO

TriTrypDb:

LdBPK_271080.1 , LdCL_270017300 , LDHU3_27.1710

Length:

415

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 6
NetGPI	no	yes: 0, no: 6

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X0M5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X0M5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	3	7	PF00656	0.617
CLV_NRD_NRD_1	159	161	PF00675	0.617
CLV_NRD_NRD_1	162	164	PF00675	0.612
CLV_NRD_NRD_1	24	26	PF00675	0.621
CLV_NRD_NRD_1	402	404	PF00675	0.776
CLV_NRD_NRD_1	97	99	PF00675	0.656
CLV_PCSK_FUR_1	160	164	PF00082	0.529
CLV_PCSK_FUR_1	95	99	PF00082	0.660
CLV_PCSK_KEX2_1	159	161	PF00082	0.604
CLV_PCSK_KEX2_1	162	164	PF00082	0.599
CLV_PCSK_KEX2_1	24	26	PF00082	0.637
CLV_PCSK_KEX2_1	288	290	PF00082	0.470
CLV_PCSK_KEX2_1	402	404	PF00082	0.785
CLV_PCSK_KEX2_1	97	99	PF00082	0.656
CLV_PCSK_PC1ET2_1	288	290	PF00082	0.468
CLV_PCSK_PC7_1	284	290	PF00082	0.474
CLV_PCSK_SKI1_1	125	129	PF00082	0.630
CLV_PCSK_SKI1_1	75	79	PF00082	0.579
DEG_APCC_DBOX_1	247	255	PF00400	0.369
DEG_Nend_Nbox_1	1	3	PF02207	0.666
DEG_SPOP_SBC_1	181	185	PF00917	0.635
DEG_SPOP_SBC_1	330	334	PF00917	0.626
DOC_MAPK_gen_1	159	167	PF00069	0.595
DOC_MAPK_gen_1	24	34	PF00069	0.576
DOC_MAPK_gen_1	97	106	PF00069	0.610
DOC_MAPK_MEF2A_6	25	34	PF00069	0.574
DOC_PP2B_LxvP_1	195	198	PF13499	0.543
DOC_PP2B_LxvP_1	389	392	PF13499	0.680
DOC_PP4_FxxP_1	237	240	PF00568	0.369
DOC_USP7_MATH_1	139	143	PF00917	0.596
DOC_USP7_MATH_1	181	185	PF00917	0.537
DOC_USP7_MATH_1	198	202	PF00917	0.546
DOC_USP7_MATH_1	318	322	PF00917	0.506
DOC_USP7_MATH_1	330	334	PF00917	0.554
DOC_USP7_MATH_1	360	364	PF00917	0.580
DOC_USP7_MATH_1	394	398	PF00917	0.695
DOC_USP7_MATH_1	47	51	PF00917	0.539
DOC_USP7_MATH_1	63	67	PF00917	0.660
DOC_WW_Pin1_4	147	152	PF00397	0.591
DOC_WW_Pin1_4	182	187	PF00397	0.757
DOC_WW_Pin1_4	25	30	PF00397	0.473
DOC_WW_Pin1_4	326	331	PF00397	0.639
DOC_WW_Pin1_4	334	339	PF00397	0.637
DOC_WW_Pin1_4	367	372	PF00397	0.636
DOC_WW_Pin1_4	66	71	PF00397	0.685
DOC_WW_Pin1_4	7	12	PF00397	0.648
DOC_WW_Pin1_4	88	93	PF00397	0.619
LIG_14-3-3_CanoR_1	154	161	PF00244	0.598
LIG_14-3-3_CanoR_1	162	168	PF00244	0.627
LIG_14-3-3_CanoR_1	248	252	PF00244	0.304
LIG_14-3-3_CanoR_1	405	414	PF00244	0.626
LIG_14-3-3_CanoR_1	64	70	PF00244	0.655
LIG_14-3-3_CanoR_1	72	78	PF00244	0.580
LIG_14-3-3_CanoR_1	97	106	PF00244	0.611
LIG_CaM_IQ_9	349	364	PF13499	0.550
LIG_DLG_GKlike_1	163	171	PF00625	0.583
LIG_FHA_1	147	153	PF00498	0.601
LIG_FHA_1	166	172	PF00498	0.498
LIG_FHA_1	175	181	PF00498	0.576
LIG_FHA_1	21	27	PF00498	0.609
LIG_FHA_1	314	320	PF00498	0.482
LIG_FHA_1	339	345	PF00498	0.596
LIG_FHA_1	63	69	PF00498	0.579
LIG_FHA_2	77	83	PF00498	0.575
LIG_LIR_Nem_3	321	325	PF02991	0.532
LIG_MYND_1	189	193	PF01753	0.527
LIG_PTB_Apo_2	223	230	PF02174	0.369
LIG_SH2_GRB2like	222	225	PF00017	0.325
LIG_SH2_SRC	312	315	PF00017	0.459
LIG_SH2_STAP1	314	318	PF00017	0.474
LIG_SH2_STAT3	301	304	PF00017	0.446
LIG_SH2_STAT3	314	317	PF00017	0.385
LIG_SH2_STAT5	222	225	PF00017	0.410
LIG_SH2_STAT5	301	304	PF00017	0.425
LIG_SH3_3	133	139	PF00018	0.546
LIG_SH3_3	183	189	PF00018	0.589
LIG_SH3_3	190	196	PF00018	0.536
LIG_SH3_3	23	29	PF00018	0.552
LIG_SH3_3	373	379	PF00018	0.697
LIG_SH3_3	390	396	PF00018	0.768
LIG_TRAF2_1	176	179	PF00917	0.653
LIG_TRAF2_1	397	400	PF00917	0.644
LIG_TRAF2_1	79	82	PF00917	0.601
LIG_WRC_WIRS_1	319	324	PF05994	0.516
MOD_CAAXbox	412	415	PF01239	0.587
MOD_CDC14_SPxK_1	69	72	PF00782	0.585
MOD_CDK_SPxK_1	66	72	PF00069	0.593
MOD_CDK_SPxxK_3	147	154	PF00069	0.591
MOD_CDK_SPxxK_3	7	14	PF00069	0.597
MOD_CDK_SPxxK_3	88	95	PF00069	0.639
MOD_CK1_1	107	113	PF00069	0.666
MOD_CK1_1	15	21	PF00069	0.587
MOD_CK1_1	155	161	PF00069	0.617
MOD_CK1_1	166	172	PF00069	0.584
MOD_CK1_1	174	180	PF00069	0.496
MOD_CK1_1	184	190	PF00069	0.515
MOD_CK1_1	329	335	PF00069	0.625
MOD_CK1_1	387	393	PF00069	0.622
MOD_CK1_1	401	407	PF00069	0.797
MOD_CK1_1	55	61	PF00069	0.620
MOD_CK1_1	66	72	PF00069	0.643
MOD_CK1_1	7	13	PF00069	0.643
MOD_CK1_1	76	82	PF00069	0.566
MOD_CK2_1	197	203	PF00069	0.723
MOD_CK2_1	394	400	PF00069	0.641
MOD_CK2_1	76	82	PF00069	0.605
MOD_DYRK1A_RPxSP_1	25	29	PF00069	0.578
MOD_GlcNHglycan	132	135	PF01048	0.566
MOD_GlcNHglycan	141	144	PF01048	0.484
MOD_GlcNHglycan	203	207	PF01048	0.560
MOD_GlcNHglycan	326	329	PF01048	0.714
MOD_GlcNHglycan	362	365	PF01048	0.553
MOD_GlcNHglycan	43	46	PF01048	0.687
MOD_GlcNHglycan	58	61	PF01048	0.561
MOD_GlcNHglycan	6	10	PF01048	0.590
MOD_GlcNHglycan	65	68	PF01048	0.621
MOD_GSK3_1	1	8	PF00069	0.597
MOD_GSK3_1	102	109	PF00069	0.747
MOD_GSK3_1	161	168	PF00069	0.614
MOD_GSK3_1	170	177	PF00069	0.559
MOD_GSK3_1	180	187	PF00069	0.538
MOD_GSK3_1	198	205	PF00069	0.574
MOD_GSK3_1	324	331	PF00069	0.636
MOD_GSK3_1	334	341	PF00069	0.624
MOD_GSK3_1	394	401	PF00069	0.740
MOD_GSK3_1	48	55	PF00069	0.594
MOD_GSK3_1	62	69	PF00069	0.588
MOD_N-GLC_2	356	358	PF02516	0.628
MOD_NEK2_1	106	111	PF00069	0.669
MOD_NEK2_1	167	172	PF00069	0.616
MOD_NEK2_1	180	185	PF00069	0.556
MOD_NEK2_1	266	271	PF00069	0.565
MOD_NEK2_1	39	44	PF00069	0.560
MOD_NEK2_1	398	403	PF00069	0.588
MOD_NEK2_1	48	53	PF00069	0.600
MOD_NEK2_1	5	10	PF00069	0.549
MOD_NEK2_1	56	61	PF00069	0.752
MOD_NEK2_1	73	78	PF00069	0.501
MOD_NEK2_2	256	261	PF00069	0.441
MOD_PIKK_1	112	118	PF00454	0.644
MOD_PIKK_1	313	319	PF00454	0.485
MOD_PIKK_1	384	390	PF00454	0.668
MOD_PIKK_1	405	411	PF00454	0.570
MOD_PIKK_1	48	54	PF00454	0.600
MOD_PKA_1	97	103	PF00069	0.650
MOD_PKA_2	112	118	PF00069	0.659
MOD_PKA_2	161	167	PF00069	0.650
MOD_PKA_2	174	180	PF00069	0.535
MOD_PKA_2	247	253	PF00069	0.369
MOD_PKA_2	379	385	PF00069	0.626
MOD_PKA_2	401	407	PF00069	0.613
MOD_PKA_2	63	69	PF00069	0.629
MOD_PKA_2	97	103	PF00069	0.656
MOD_PKB_1	403	411	PF00069	0.572
MOD_PKB_1	95	103	PF00069	0.674
MOD_Plk_4	167	173	PF00069	0.609
MOD_Plk_4	73	79	PF00069	0.583
MOD_ProDKin_1	147	153	PF00069	0.589
MOD_ProDKin_1	182	188	PF00069	0.754
MOD_ProDKin_1	25	31	PF00069	0.474
MOD_ProDKin_1	326	332	PF00069	0.642
MOD_ProDKin_1	334	340	PF00069	0.639
MOD_ProDKin_1	367	373	PF00069	0.634
MOD_ProDKin_1	66	72	PF00069	0.686
MOD_ProDKin_1	7	13	PF00069	0.649
MOD_ProDKin_1	88	94	PF00069	0.621
TRG_ER_diArg_1	159	162	PF00400	0.571
TRG_ER_diArg_1	24	27	PF00400	0.621
TRG_ER_diArg_1	307	310	PF00400	0.417
TRG_ER_diArg_1	402	405	PF00400	0.770
TRG_ER_diArg_1	95	98	PF00400	0.657
TRG_Pf-PMV_PEXEL_1	261	265	PF00026	0.530

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1HZY3	Leptomonas seymouri	34%	88%
A4HFP6	Leishmania braziliensis	52%	100%
E9AD98	Leishmania major	86%	100%
E9AHF8	Leishmania infantum	100%	100%
E9AZ23	Leishmania mexicana (strain MHOM/GT/2001/U1103)	80%	98%