Stress_responsive_A/B_Barrel_Domain_putative/Pfam:PF07876

Quick info Annotations Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

Stress responsive A/B Barrel Domain, putative

Species:

Leishmania donovani

UniProt:

A0A3S7X0I8_LEIDO

TriTrypDb:

LdBPK_270610.1 , LdCL_270012600 , LDHU3_27.0990

Length:

127

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 11
NetGPI	no	yes: 0, no: 11

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X0I8

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X0I8

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	69	73	PF00656	0.402
CLV_PCSK_KEX2_1	46	48	PF00082	0.357
CLV_PCSK_PC1ET2_1	46	48	PF00082	0.357
CLV_PCSK_PC7_1	42	48	PF00082	0.307
CLV_PCSK_SKI1_1	113	117	PF00082	0.460
CLV_PCSK_SKI1_1	42	46	PF00082	0.437
DEG_APCC_DBOX_1	41	49	PF00400	0.307
DEG_Nend_UBRbox_2	1	3	PF02207	0.706
DOC_ANK_TNKS_1	48	55	PF00023	0.337
DOC_CYCLIN_yCln2_LP_2	32	38	PF00134	0.357
DOC_MAPK_gen_1	110	120	PF00069	0.391
DOC_MAPK_gen_1	31	38	PF00069	0.357
DOC_WW_Pin1_4	1	6	PF00397	0.524
LIG_14-3-3_CanoR_1	113	118	PF00244	0.445
LIG_14-3-3_CanoR_1	47	53	PF00244	0.447
LIG_APCC_ABBAyCdc20_2	33	39	PF00400	0.282
LIG_FHA_1	76	82	PF00498	0.329
LIG_FHA_2	114	120	PF00498	0.371
LIG_LIR_Gen_1	119	127	PF02991	0.500
LIG_LIR_Nem_3	119	123	PF02991	0.371
LIG_NRBOX	40	46	PF00104	0.337
LIG_PDZ_Class_1	122	127	PF00595	0.521
LIG_SH2_STAT5	106	109	PF00017	0.336
LIG_SH2_STAT5	90	93	PF00017	0.367
LIG_TRAF2_1	8	11	PF00917	0.657
MOD_CK1_1	6	12	PF00069	0.572
MOD_CK1_1	67	73	PF00069	0.406
MOD_CK2_1	106	112	PF00069	0.371
MOD_GlcNHglycan	66	69	PF01048	0.442
MOD_GlcNHglycan	72	75	PF01048	0.407
MOD_GSK3_1	60	67	PF00069	0.434
MOD_N-GLC_1	6	11	PF02516	0.525
MOD_N-GLC_1	64	69	PF02516	0.347
MOD_NEK2_1	60	65	PF00069	0.351
MOD_NEK2_1	93	98	PF00069	0.470
MOD_PKA_2	48	54	PF00069	0.481
MOD_Plk_4	113	119	PF00069	0.331
MOD_ProDKin_1	1	7	PF00069	0.520
TRG_ENDOCYTIC_2	90	93	PF00928	0.400

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N0P783	Leptomonas seymouri	60%	99%
A0A0S4JU83	Bodo saltans	38%	100%
A0A1X0P411	Trypanosomatidae	44%	100%
A0A3R7NRY9	Trypanosoma rangeli	34%	100%
A4HFJ9	Leishmania braziliensis	78%	100%
E9AD52	Leishmania major	94%	100%
E9AHE7	Leishmania infantum	100%	100%
E9AYX7	Leishmania mexicana (strain MHOM/GT/2001/U1103)	89%	100%
V5AU50	Trypanosoma cruzi	42%	100%
V5DA48	Trypanosoma cruzi	36%	100%