Uncharacterized protein

Quick info Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:

Gene product:

hypothetical protein

Species:

Leishmania donovani

UniProt:

A0A3S7X0G5_LEIDO

TriTrypDb:

LdCL_270010900 , LDHU3_27.0780

Length:

989

Localization

Secreted promastigote


Source	Evidence on protein	Close homologs
Cuervo et al.	no	yes: 0
Hassani et al.	no	yes: 0
Forrest at al. (metacyclic)	no	yes: 0
Forrest at al. (procyclic)	no	yes: 0
Silverman et al.	no	yes: 0
Pissara et al.	no	yes: 0

Secreted amastigote


Source	Evidence on protein	Close homologs
Pires et al.	no	yes: 0

Exosome


Source	Evidence on protein	Close homologs
Silverman et al.	no	yes: 0

Glycosome


Source	Evidence on protein	Close homologs
Jamdhade et al.	no	yes: 0

Predictions


Source	Evidence on protein	Close homologs
DeepLoc
SignalP6	no	yes: 0, no: 7
NetGPI	no	yes: 0, no: 7

Could not find GO cellular_component term for this entry.

Expansion

Sequence features

A0A3S7X0G5

Sequence

MSA

Disorder

Secondary

Topology

Domains

SignalP

GPI

Phosphorylations

ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X0G5

Putative motif mimicry


Leishmania	From	To	Domain/Motif	Score
CLV_C14_Caspase3-7	4	8	PF00656	0.789
CLV_NRD_NRD_1	326	328	PF00675	0.629
CLV_NRD_NRD_1	343	345	PF00675	0.458
CLV_NRD_NRD_1	360	362	PF00675	0.467
CLV_NRD_NRD_1	417	419	PF00675	0.611
CLV_NRD_NRD_1	436	438	PF00675	0.716
CLV_NRD_NRD_1	505	507	PF00675	0.561
CLV_NRD_NRD_1	561	563	PF00675	0.560
CLV_NRD_NRD_1	716	718	PF00675	0.595
CLV_NRD_NRD_1	724	726	PF00675	0.510
CLV_NRD_NRD_1	729	731	PF00675	0.480
CLV_NRD_NRD_1	752	754	PF00675	0.608
CLV_NRD_NRD_1	776	778	PF00675	0.571
CLV_NRD_NRD_1	885	887	PF00675	0.777
CLV_NRD_NRD_1	983	985	PF00675	0.623
CLV_PCSK_FUR_1	324	328	PF00082	0.629
CLV_PCSK_FUR_1	341	345	PF00082	0.646
CLV_PCSK_FUR_1	699	703	PF00082	0.779
CLV_PCSK_FUR_1	714	718	PF00082	0.415
CLV_PCSK_KEX2_1	324	326	PF00082	0.613
CLV_PCSK_KEX2_1	343	345	PF00082	0.454
CLV_PCSK_KEX2_1	360	362	PF00082	0.640
CLV_PCSK_KEX2_1	417	419	PF00082	0.611
CLV_PCSK_KEX2_1	435	437	PF00082	0.744
CLV_PCSK_KEX2_1	505	507	PF00082	0.649
CLV_PCSK_KEX2_1	563	565	PF00082	0.520
CLV_PCSK_KEX2_1	678	680	PF00082	0.695
CLV_PCSK_KEX2_1	701	703	PF00082	0.683
CLV_PCSK_KEX2_1	716	718	PF00082	0.460
CLV_PCSK_KEX2_1	731	733	PF00082	0.458
CLV_PCSK_KEX2_1	75	77	PF00082	0.672
CLV_PCSK_KEX2_1	752	754	PF00082	0.574
CLV_PCSK_KEX2_1	776	778	PF00082	0.571
CLV_PCSK_KEX2_1	885	887	PF00082	0.772
CLV_PCSK_KEX2_1	983	985	PF00082	0.621
CLV_PCSK_PC1ET2_1	563	565	PF00082	0.630
CLV_PCSK_PC1ET2_1	678	680	PF00082	0.704
CLV_PCSK_PC1ET2_1	701	703	PF00082	0.683
CLV_PCSK_PC1ET2_1	731	733	PF00082	0.622
CLV_PCSK_PC1ET2_1	75	77	PF00082	0.603
CLV_PCSK_PC7_1	979	985	PF00082	0.620
CLV_PCSK_SKI1_1	303	307	PF00082	0.584
CLV_PCSK_SKI1_1	383	387	PF00082	0.593
CLV_PCSK_SKI1_1	401	405	PF00082	0.576
CLV_PCSK_SKI1_1	417	421	PF00082	0.455
CLV_PCSK_SKI1_1	422	426	PF00082	0.560
CLV_PCSK_SKI1_1	571	575	PF00082	0.485
CLV_PCSK_SKI1_1	606	610	PF00082	0.615
CLV_PCSK_SKI1_1	813	817	PF00082	0.634
CLV_PCSK_SKI1_1	971	975	PF00082	0.542
DEG_APCC_DBOX_1	605	613	PF00400	0.604
DEG_SCF_FBW7_1	650	655	PF00400	0.603
DEG_SCF_FBW7_1	852	857	PF00400	0.563
DEG_SPOP_SBC_1	77	81	PF00917	0.755
DEG_SPOP_SBC_1	824	828	PF00917	0.664
DOC_CKS1_1	131	136	PF01111	0.586
DOC_CKS1_1	190	195	PF01111	0.784
DOC_CYCLIN_RxL_1	380	389	PF00134	0.721
DOC_CYCLIN_RxL_1	809	820	PF00134	0.690
DOC_CYCLIN_yCln2_LP_2	261	267	PF00134	0.581
DOC_MAPK_gen_1	303	312	PF00069	0.584
DOC_MAPK_gen_1	548	558	PF00069	0.566
DOC_MAPK_gen_1	966	975	PF00069	0.585
DOC_MAPK_MEF2A_6	760	767	PF00069	0.641
DOC_PP4_FxxP_1	25	28	PF00568	0.664
DOC_USP7_MATH_1	104	108	PF00917	0.787
DOC_USP7_MATH_1	157	161	PF00917	0.685
DOC_USP7_MATH_1	165	169	PF00917	0.659
DOC_USP7_MATH_1	172	176	PF00917	0.570
DOC_USP7_MATH_1	181	185	PF00917	0.515
DOC_USP7_MATH_1	227	231	PF00917	0.737
DOC_USP7_MATH_1	284	288	PF00917	0.697
DOC_USP7_MATH_1	478	482	PF00917	0.723
DOC_USP7_MATH_1	52	56	PF00917	0.769
DOC_USP7_MATH_1	652	656	PF00917	0.564
DOC_USP7_MATH_1	766	770	PF00917	0.712
DOC_USP7_MATH_1	77	81	PF00917	0.805
DOC_USP7_MATH_1	792	796	PF00917	0.632
DOC_USP7_MATH_1	798	802	PF00917	0.668
DOC_USP7_MATH_1	854	858	PF00917	0.593
DOC_USP7_MATH_1	872	876	PF00917	0.481
DOC_USP7_MATH_1	902	906	PF00917	0.829
DOC_USP7_MATH_1	933	937	PF00917	0.712
DOC_USP7_MATH_1	940	944	PF00917	0.695
DOC_USP7_UBL2_3	6	10	PF12436	0.700
DOC_WW_Pin1_4	11	16	PF00397	0.731
DOC_WW_Pin1_4	130	135	PF00397	0.611
DOC_WW_Pin1_4	140	145	PF00397	0.753
DOC_WW_Pin1_4	163	168	PF00397	0.709
DOC_WW_Pin1_4	173	178	PF00397	0.721
DOC_WW_Pin1_4	186	191	PF00397	0.717
DOC_WW_Pin1_4	196	201	PF00397	0.744
DOC_WW_Pin1_4	333	338	PF00397	0.602
DOC_WW_Pin1_4	396	401	PF00397	0.680
DOC_WW_Pin1_4	436	441	PF00397	0.653
DOC_WW_Pin1_4	45	50	PF00397	0.809
DOC_WW_Pin1_4	5	10	PF00397	0.831
DOC_WW_Pin1_4	648	653	PF00397	0.632
DOC_WW_Pin1_4	690	695	PF00397	0.652
DOC_WW_Pin1_4	83	88	PF00397	0.831
DOC_WW_Pin1_4	838	843	PF00397	0.808
DOC_WW_Pin1_4	850	855	PF00397	0.628
DOC_WW_Pin1_4	860	865	PF00397	0.674
DOC_WW_Pin1_4	959	964	PF00397	0.595
DOC_WW_Pin1_4	98	103	PF00397	0.791
LIG_14-3-3_CanoR_1	183	193	PF00244	0.742
LIG_14-3-3_CanoR_1	262	268	PF00244	0.756
LIG_14-3-3_CanoR_1	343	349	PF00244	0.608
LIG_14-3-3_CanoR_1	383	388	PF00244	0.597
LIG_14-3-3_CanoR_1	401	407	PF00244	0.570
LIG_14-3-3_CanoR_1	594	598	PF00244	0.553
LIG_14-3-3_CanoR_1	629	638	PF00244	0.544
LIG_14-3-3_CanoR_1	669	677	PF00244	0.731
LIG_14-3-3_CanoR_1	818	825	PF00244	0.727
LIG_14-3-3_CanoR_1	911	917	PF00244	0.759
LIG_BIR_III_2	482	486	PF00653	0.554
LIG_BRCT_BRCA1_1	167	171	PF00533	0.705
LIG_BRCT_BRCA1_1	378	382	PF00533	0.683
LIG_CtBP_PxDLS_1	951	955	PF00389	0.609
LIG_eIF4E_1	569	575	PF01652	0.571
LIG_FHA_1	141	147	PF00498	0.737
LIG_FHA_1	32	38	PF00498	0.766
LIG_FHA_1	387	393	PF00498	0.660
LIG_FHA_1	497	503	PF00498	0.678
LIG_FHA_1	762	768	PF00498	0.611
LIG_FHA_1	818	824	PF00498	0.601
LIG_FHA_2	410	416	PF00498	0.585
LIG_FHA_2	511	517	PF00498	0.486
LIG_FHA_2	631	637	PF00498	0.590
LIG_FHA_2	768	774	PF00498	0.625
LIG_FHA_2	79	85	PF00498	0.751
LIG_FHA_2	960	966	PF00498	0.651
LIG_KLC1_Yacidic_2	294	298	PF13176	0.702
LIG_LIR_Apic_2	24	28	PF02991	0.579
LIG_LIR_Gen_1	106	117	PF02991	0.520
LIG_LIR_Gen_1	404	414	PF02991	0.561
LIG_LIR_Gen_1	634	645	PF02991	0.446
LIG_LIR_Nem_3	106	112	PF02991	0.526
LIG_LIR_Nem_3	379	385	PF02991	0.600
LIG_LIR_Nem_3	404	410	PF02991	0.565
LIG_LIR_Nem_3	568	573	PF02991	0.480
LIG_LIR_Nem_3	634	640	PF02991	0.453
LIG_RPA_C_Fungi	871	883	PF08784	0.556
LIG_SH2_CRK	570	574	PF00017	0.497
LIG_SH2_NCK_1	411	415	PF00017	0.606
LIG_SH2_SRC	296	299	PF00017	0.560
LIG_SH2_STAP1	244	248	PF00017	0.696
LIG_SH2_STAP1	338	342	PF00017	0.584
LIG_SH2_STAP1	479	483	PF00017	0.701
LIG_SH2_STAT3	745	748	PF00017	0.744
LIG_SH2_STAT5	130	133	PF00017	0.586
LIG_SH2_STAT5	296	299	PF00017	0.614
LIG_SH2_STAT5	411	414	PF00017	0.656
LIG_SH2_STAT5	644	647	PF00017	0.490
LIG_SH2_STAT5	745	748	PF00017	0.744
LIG_SH2_STAT5	779	782	PF00017	0.528
LIG_SH3_1	235	241	PF00018	0.567
LIG_SH3_1	327	333	PF00018	0.599
LIG_SH3_1	659	665	PF00018	0.604
LIG_SH3_1	885	891	PF00018	0.734
LIG_SH3_2	147	152	PF14604	0.671
LIG_SH3_2	888	893	PF14604	0.740
LIG_SH3_3	128	134	PF00018	0.585
LIG_SH3_3	141	147	PF00018	0.765
LIG_SH3_3	187	193	PF00018	0.737
LIG_SH3_3	235	241	PF00018	0.567
LIG_SH3_3	327	333	PF00018	0.599
LIG_SH3_3	43	49	PF00018	0.735
LIG_SH3_3	659	665	PF00018	0.600
LIG_SH3_3	760	766	PF00018	0.566
LIG_SH3_3	885	891	PF00018	0.734
LIG_SH3_3	914	920	PF00018	0.663
LIG_SUMO_SIM_anti_2	636	642	PF11976	0.487
LIG_SUMO_SIM_par_1	383	389	PF11976	0.646
LIG_SUMO_SIM_par_1	498	504	PF11976	0.721
LIG_TRAF2_1	315	318	PF00917	0.588
LIG_WW_3	661	665	PF00397	0.523
MOD_CDC14_SPxK_1	439	442	PF00782	0.684
MOD_CDK_SPK_2	396	401	PF00069	0.680
MOD_CDK_SPK_2	5	10	PF00069	0.743
MOD_CDK_SPxK_1	436	442	PF00069	0.623
MOD_CDK_SPxxK_3	838	845	PF00069	0.809
MOD_CDK_SPxxK_3	959	966	PF00069	0.626
MOD_CK1_1	107	113	PF00069	0.729
MOD_CK1_1	14	20	PF00069	0.735
MOD_CK1_1	160	166	PF00069	0.776
MOD_CK1_1	184	190	PF00069	0.732
MOD_CK1_1	501	507	PF00069	0.578
MOD_CK1_1	673	679	PF00069	0.767
MOD_CK1_1	689	695	PF00069	0.590
MOD_CK1_1	769	775	PF00069	0.672
MOD_CK1_1	863	869	PF00069	0.683
MOD_CK1_1	936	942	PF00069	0.727
MOD_CK2_1	250	256	PF00069	0.662
MOD_CK2_1	409	415	PF00069	0.584
MOD_CK2_1	510	516	PF00069	0.483
MOD_CK2_1	610	616	PF00069	0.445
MOD_CK2_1	630	636	PF00069	0.563
MOD_CK2_1	767	773	PF00069	0.633
MOD_CK2_1	78	84	PF00069	0.751
MOD_CK2_1	824	830	PF00069	0.719
MOD_CK2_1	950	956	PF00069	0.678
MOD_CK2_1	958	964	PF00069	0.663
MOD_Cter_Amidation	72	75	PF01082	0.744
MOD_Cter_Amidation	883	886	PF01082	0.739
MOD_DYRK1A_RPxSP_1	838	842	PF00069	0.739
MOD_GlcNHglycan	135	138	PF01048	0.658
MOD_GlcNHglycan	159	162	PF01048	0.730
MOD_GlcNHglycan	245	248	PF01048	0.634
MOD_GlcNHglycan	274	277	PF01048	0.767
MOD_GlcNHglycan	462	465	PF01048	0.662
MOD_GlcNHglycan	513	516	PF01048	0.690
MOD_GlcNHglycan	612	615	PF01048	0.428
MOD_GlcNHglycan	654	657	PF01048	0.528
MOD_GlcNHglycan	672	675	PF01048	0.551
MOD_GlcNHglycan	681	684	PF01048	0.702
MOD_GlcNHglycan	688	691	PF01048	0.578
MOD_GlcNHglycan	780	783	PF01048	0.603
MOD_GlcNHglycan	800	803	PF01048	0.692
MOD_GlcNHglycan	833	836	PF01048	0.760
MOD_GlcNHglycan	856	859	PF01048	0.811
MOD_GlcNHglycan	870	873	PF01048	0.640
MOD_GlcNHglycan	878	881	PF01048	0.768
MOD_GlcNHglycan	905	908	PF01048	0.785
MOD_GlcNHglycan	914	917	PF01048	0.816
MOD_GlcNHglycan	936	939	PF01048	0.790
MOD_GlcNHglycan	984	987	PF01048	0.717
MOD_GSK3_1	129	136	PF00069	0.790
MOD_GSK3_1	156	163	PF00069	0.778
MOD_GSK3_1	182	189	PF00069	0.626
MOD_GSK3_1	213	220	PF00069	0.722
MOD_GSK3_1	223	230	PF00069	0.636
MOD_GSK3_1	239	246	PF00069	0.754
MOD_GSK3_1	26	33	PF00069	0.645
MOD_GSK3_1	272	279	PF00069	0.642
MOD_GSK3_1	456	463	PF00069	0.638
MOD_GSK3_1	648	655	PF00069	0.612
MOD_GSK3_1	686	693	PF00069	0.696
MOD_GSK3_1	792	799	PF00069	0.679
MOD_GSK3_1	825	832	PF00069	0.723
MOD_GSK3_1	850	857	PF00069	0.730
MOD_GSK3_1	868	875	PF00069	0.675
MOD_GSK3_1	903	910	PF00069	0.603
MOD_GSK3_1	936	943	PF00069	0.620
MOD_GSK3_1	94	101	PF00069	0.797
MOD_N-GLC_1	805	810	PF02516	0.723
MOD_N-GLC_2	59	61	PF02516	0.826
MOD_NEK2_1	201	206	PF00069	0.686
MOD_NEK2_1	31	36	PF00069	0.704
MOD_NEK2_1	784	789	PF00069	0.490
MOD_NEK2_1	805	810	PF00069	0.685
MOD_NEK2_2	402	407	PF00069	0.642
MOD_PIKK_1	213	219	PF00454	0.729
MOD_PIKK_1	26	32	PF00454	0.706
MOD_PIKK_1	266	272	PF00454	0.687
MOD_PIKK_1	725	731	PF00454	0.661
MOD_PKA_1	367	373	PF00069	0.567
MOD_PKA_1	725	731	PF00069	0.573
MOD_PKA_2	182	188	PF00069	0.783
MOD_PKA_2	31	37	PF00069	0.742
MOD_PKA_2	593	599	PF00069	0.554
MOD_PKA_2	767	773	PF00069	0.693
MOD_PKA_2	817	823	PF00069	0.681
MOD_PKA_2	933	939	PF00069	0.621
MOD_PKA_2	940	946	PF00069	0.565
MOD_PKA_2	982	988	PF00069	0.662
MOD_PKB_1	829	837	PF00069	0.830
MOD_Plk_1	743	749	PF00069	0.741
MOD_Plk_1	761	767	PF00069	0.421
MOD_Plk_1	872	878	PF00069	0.547
MOD_Plk_1	94	100	PF00069	0.761
MOD_Plk_2-3	409	415	PF00069	0.548
MOD_Plk_2-3	950	956	PF00069	0.660
MOD_Plk_4	239	245	PF00069	0.616
MOD_Plk_4	402	408	PF00069	0.690
MOD_Plk_4	792	798	PF00069	0.572
MOD_Plk_4	950	956	PF00069	0.655
MOD_ProDKin_1	130	136	PF00069	0.612
MOD_ProDKin_1	140	146	PF00069	0.754
MOD_ProDKin_1	163	169	PF00069	0.678
MOD_ProDKin_1	173	179	PF00069	0.719
MOD_ProDKin_1	186	192	PF00069	0.716
MOD_ProDKin_1	196	202	PF00069	0.742
MOD_ProDKin_1	333	339	PF00069	0.595
MOD_ProDKin_1	396	402	PF00069	0.674
MOD_ProDKin_1	436	442	PF00069	0.650
MOD_ProDKin_1	45	51	PF00069	0.805
MOD_ProDKin_1	5	11	PF00069	0.830
MOD_ProDKin_1	648	654	PF00069	0.639
MOD_ProDKin_1	690	696	PF00069	0.651
MOD_ProDKin_1	83	89	PF00069	0.832
MOD_ProDKin_1	838	844	PF00069	0.809
MOD_ProDKin_1	850	856	PF00069	0.626
MOD_ProDKin_1	860	866	PF00069	0.674
MOD_ProDKin_1	959	965	PF00069	0.592
MOD_ProDKin_1	98	104	PF00069	0.790
MOD_SUMO_for_1	538	541	PF00179	0.663
MOD_SUMO_for_1	700	703	PF00179	0.704
MOD_SUMO_rev_2	421	426	PF00179	0.571
MOD_SUMO_rev_2	557	565	PF00179	0.612
TRG_DiLeu_BaEn_1	616	621	PF01217	0.517
TRG_DiLeu_BaEn_1	950	955	PF01217	0.661
TRG_DiLeu_BaLyEn_6	750	755	PF01217	0.620
TRG_ENDOCYTIC_2	109	112	PF00928	0.516
TRG_ENDOCYTIC_2	570	573	PF00928	0.507
TRG_ER_diArg_1	324	327	PF00400	0.623
TRG_ER_diArg_1	341	344	PF00400	0.489
TRG_ER_diArg_1	359	361	PF00400	0.536
TRG_ER_diArg_1	435	437	PF00400	0.779
TRG_ER_diArg_1	505	507	PF00400	0.561
TRG_ER_diArg_1	562	565	PF00400	0.542
TRG_ER_diArg_1	713	716	PF00400	0.621
TRG_ER_diArg_1	751	753	PF00400	0.613
TRG_ER_diArg_1	775	777	PF00400	0.576
TRG_ER_diArg_1	966	969	PF00400	0.680
TRG_NLS_Bipartite_1	716	734	PF00514	0.422
TRG_Pf-PMV_PEXEL_1	579	583	PF00026	0.511
TRG_Pf-PMV_PEXEL_1	732	736	PF00026	0.570

Homologs


Protein	Taxonomy	Sequence identity	Coverage
A0A0N1PC69	Leptomonas seymouri	47%	95%
A0A1X0P481	Trypanosomatidae	28%	100%
A4HFI6	Leishmania braziliensis	68%	99%
E9AD37	Leishmania major	88%	100%
E9AHD0	Leishmania infantum	99%	100%
E9AYW1	Leishmania mexicana (strain MHOM/GT/2001/U1103)	82%	96%