LeishMANIAdb
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Uncharacterized protein

Quick info Annotations Function or PPIs Localization Expansion Sequence features Structure Putative motif mimicry Homologs Download

Quick info

Protein:
Uncharacterized protein
Gene product:
hypothetical protein, conserved
Species:
Leishmania donovani
UniProt:
A0A3S7X0B8_LEIDO
TriTrypDb:
LdBPK_270070.1 , LdCL_270005600 , LDHU3_27.0090
Length:
313

Annotations

Annotations by Jardim et al.

Uncharacterized Protein, Uncharacterized

Localization

Secreted promastigote
Source Evidence on protein Close homologs
Cuervo et al. no yes: 0
Hassani et al. no yes: 0
Forrest at al. (metacyclic) no yes: 0
Forrest at al. (procyclic) no yes: 0
Silverman et al. no yes: 0
Pissara et al. no yes: 5
Secreted amastigote
Source Evidence on protein Close homologs
Pires et al. no yes: 0
Exosome
Source Evidence on protein Close homologs
Silverman et al. no yes: 0
Glycosome
Source Evidence on protein Close homologs
Jamdhade et al. no yes: 0
Predictions
Source Evidence on protein Close homologs
DeepLoc
SignalP6 yes yes: 10, no: 0
NetGPI no yes: 0, no: 10
Cellular components
TermNameLevelCount
GO:0016020 membrane 2 7
GO:0110165 cellular anatomical entity 1 7
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Expansion

Sequence features

A0A3S7X0B8
Sequence
MSA
Disorder
Secondary
Topology
Domains
SignalP
GPI
Phosphorylations
ELMs

Structure

Predicted structure by AlphaFold2

Related structures:

AlphaFold database: A0A3S7X0B8

Putative motif mimicry

LeishmaniaFromToDomain/MotifScore
CLV_C14_Caspase3-7 137 141 PF00656 0.368
CLV_C14_Caspase3-7 226 230 PF00656 0.414
CLV_C14_Caspase3-7 294 298 PF00656 0.663
CLV_NRD_NRD_1 210 212 PF00675 0.676
CLV_NRD_NRD_1 213 215 PF00675 0.682
CLV_NRD_NRD_1 244 246 PF00675 0.526
CLV_PCSK_FUR_1 211 215 PF00082 0.671
CLV_PCSK_KEX2_1 194 196 PF00082 0.723
CLV_PCSK_KEX2_1 208 210 PF00082 0.634
CLV_PCSK_KEX2_1 212 214 PF00082 0.658
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Homologs

ProteinTaxonomySequence identityCoverage
A0A0N1PD93 Leptomonas seymouri 51% 100%
A0A1X0NLP1 Trypanosomatidae 28% 100%
A0A3R7RDJ4 Trypanosoma rangeli 26% 100%
A4HFC6 Leishmania braziliensis 72% 99%
A4I2K3 Leishmania infantum 100% 100%
C9ZKU3 Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972) 24% 100%
E9ACY4 Leishmania major 90% 100%
E9AYQ9 Leishmania mexicana (strain MHOM/GT/2001/U1103) 88% 100%
V5BKS2 Trypanosoma cruzi 28% 100%
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LeishMANIAdb - Server version: v0.0.2. - Database version: v0.0.1. - ChangeLog - © 2022-2025 Protein Bioinformatics Research Group, Institute of Enzymology, RCNS